"Zinc Fingers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.
- Zinc Fingers
- Finger, Zinc
- Fingers, Zinc
- Zinc Finger
- Zinc Finger Motifs
- Motif, Zinc Finger
- Motifs, Zinc Finger
- Zinc Finger Motif
Below are MeSH descriptors whose meaning is more general than "Zinc Fingers".
Below are MeSH descriptors whose meaning is more specific than "Zinc Fingers".
This graph shows the total number of publications written about "Zinc Fingers" by people in the URMC Research Network by year, and whether "Zinc Fingers" was a major or minor topic of these publication.