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5-Aminolevulinate Synthetase

"5-Aminolevulinate Synthetase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37.


publications
This graph shows the total number of publications written about "5-Aminolevulinate Synthetase" by people in the URMC Research Network by year, and whether "5-Aminolevulinate Synthetase" was a major or minor topic of these publication.