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Proto-Oncogene Proteins c-bcr

"Proto-Oncogene Proteins c-bcr" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
Proto-oncogene protein bcr is a serine-threonine kinase that functions as a negative regulator of CELL PROLIFERATION and NEOPLASTIC CELL TRANSFORMATION. It is commonly fused with cellular abl protein to form BCR-ABL FUSION PROTEINS in PHILADELPHIA CHROMOSOME positive LEUKEMIA patients.


publications
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-bcr" by people in the URMC Research Network by year, and whether "Proto-Oncogene Proteins c-bcr" was a major or minor topic of these publication.