GTP-Binding Protein gamma Subunits
This graph shows the total number of publications written about "GTP-Binding Protein gamma Subunits" by people in the URMC Research Network by year, and whether "GTP-Binding Protein gamma Subunits" was a major or minor topic of these publication.
Below are the most recent publications written about "GTP-Binding Protein gamma Subunits" by people in Profiles.
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Lin Y, Smrcka AV. Understanding molecular recognition by G protein ß? subunits on the path to pharmacological targeting. Mol Pharmacol. 2011 Oct; 80(4):551-7.
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Seneviratne AM, Burroughs M, Giralt E, Smrcka AV. Direct-reversible binding of small molecules to G protein ß? subunits. Biochim Biophys Acta. 2011 Sep; 1814(9):1210-8.
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Park MS, Smrcka AV, Stern HA. Conformational flexibility and binding interactions of the G protein ß? heterodimer. Proteins. 2011 Feb; 79(2):518-27.
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Dessal AL, Prades R, Giralt E, Smrcka AV. Rational design of a selective covalent modifier of G protein ß? subunits. Mol Pharmacol. 2011 Jan; 79(1):24-33.
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Casey LM, Pistner AR, Belmonte SL, Migdalovich D, Stolpnik O, Nwakanma FE, Vorobiof G, Dunaevsky O, Matavel A, Lopes CM, Smrcka AV, Blaxall BC. Small molecule disruption of G beta gamma signaling inhibits the progression of heart failure. Circ Res. 2010 Aug 20; 107(4):532-9.
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Aistrup GL, Villuendas R, Ng J, Gilchrist A, Lynch TW, Gordon D, Cokic I, Mottl S, Zhou R, Dean DA, Wasserstrom JA, Goldberger JJ, Kadish AH, Arora R. Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation. Cardiovasc Res. 2009 Aug 1; 83(3):481-92.
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Smrcka AV. G protein betagamma subunits: central mediators of G protein-coupled receptor signaling. Cell Mol Life Sci. 2008 Jul; 65(14):2191-214.
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Smrcka AV, Lehmann DM, Dessal AL. G protein betagamma subunits as targets for small molecule therapeutic development. Comb Chem High Throughput Screen. 2008 Jun; 11(5):382-95.
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Lehmann DM, Seneviratne AM, Smrcka AV. Small molecule disruption of G protein beta gamma subunit signaling inhibits neutrophil chemotaxis and inflammation. Mol Pharmacol. 2008 Feb; 73(2):410-8.
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Yuan C, Sato M, Lanier SM, Smrcka AV. Signaling by a non-dissociated complex of G Protein betagamma and alpha subunits stimulated by a receptor-independent activator of G protein signaling, AGS8. J Biol Chem. 2007 Jul 6; 282(27):19938-47.