"Huntington Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
- Huntington Disease
- Huntington Chorea
- Chorea, Huntington
- Huntington's Disease
- Huntington Chronic Progressive Hereditary Chorea
- Progressive Chorea, Hereditary, Chronic (Huntington)
- Chronic Progressive Hereditary Chorea (Huntington)
- Chorea, Chronic Progressive Hereditary (Huntington)
- Huntington's Chorea
- Chorea, Huntington's
- Progressive Chorea, Chronic Hereditary (Huntington)
Juvenile Huntington Disease
- Juvenile Huntington Disease
- Juvenile-Onset Huntington Disease
- Juvenile Onset Huntington Disease
- Huntington Disease, Juvenile-Onset
- Huntington Disease, Juvenile Onset
- Huntington Disease, Juvenile
Below are MeSH descriptors whose meaning is more general than "Huntington Disease".
Below are MeSH descriptors whose meaning is more specific than "Huntington Disease".
This graph shows the total number of publications written about "Huntington Disease" by people in the URMC Research Network by year, and whether "Huntington Disease" was a major or minor topic of these publication.