URMC Research Network

Find People
Keyword
Last Name
 
More Search Options

Platelet Glycoprotein GPIIb-IIIa Complex

"Platelet Glycoprotein GPIIb-IIIa Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. It is an integrin complex containing INTEGRIN ALPHAIIB and INTEGRIN BETA3 which recognizes the arginine-glycine-aspartic acid (RGD) sequence present on several adhesive proteins. As such, it is a receptor for FIBRINOGEN; VON WILLEBRAND FACTOR; FIBRONECTIN; VITRONECTIN; and THROMBOSPONDINS. A deficiency of GPIIb-IIIa results in GLANZMANN THROMBASTHENIA.


publications
This graph shows the total number of publications written about "Platelet Glycoprotein GPIIb-IIIa Complex" by people in the URMC Research Network by year, and whether "Platelet Glycoprotein GPIIb-IIIa Complex" was a major or minor topic of these publication.