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Proto-Oncogene Proteins c-abl

"Proto-Oncogene Proteins c-abl" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.


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This graph shows the total number of publications written about "Proto-Oncogene Proteins c-abl" by people in the URMC Research Network by year, and whether "Proto-Oncogene Proteins c-abl" was a major or minor topic of these publication.
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