Amyotrophic Lateral Sclerosis
"Amyotrophic Lateral Sclerosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
|Amyotrophic Lateral Sclerosis
- Amyotrophic Lateral Sclerosis
- Lateral Scleroses, Amyotrophic
- Sclerosis, Amyotrophic Lateral
- Gehrig's Disease
- Gehrig Disease
- Gehrigs Disease
- Lou Gehrig Disease
- Lou-Gehrigs Disease
- Disease, Lou-Gehrigs
- Motor Neuron Disease, Amyotrophic Lateral Sclerosis
- ALS (Amyotrophic Lateral Sclerosis)
- Lou Gehrig's Disease
Amyotrophic Lateral Sclerosis, Guam Form
- Amyotrophic Lateral Sclerosis, Guam Form
- Amyotrophic Lateral Sclerosis-Parkinsonism-dementia Complex 1
- Amyotrophic Lateral Sclerosis Parkinsonism dementia Complex 1
- Amyotrophic lateral sclerosis, Parkinsonism-Dementia complex of Guam
- Amyotrophic lateral sclerosis, Parkinsonism Dementia complex of Guam
- Guam Disease
- Disease, Guam
- Guam Form of Amyotrophic Lateral Sclerosis
Below are MeSH descriptors whose meaning is more general than "Amyotrophic Lateral Sclerosis".
Below are MeSH descriptors whose meaning is more specific than "Amyotrophic Lateral Sclerosis".
This graph shows the total number of publications written about "Amyotrophic Lateral Sclerosis" by people in the URMC Research Network by year, and whether "Amyotrophic Lateral Sclerosis" was a major or minor topic of these publication.