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Tissue Inhibitor of Metalloproteinase-2

"Tissue Inhibitor of Metalloproteinase-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21-kDa nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase A by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of TIMP-2 has been shown to inhibit invasive and metastatic activity of tumor cells and decrease tumor growth in vivo.


publications
This graph shows the total number of publications written about "Tissue Inhibitor of Metalloproteinase-2" by people in the URMC Research Network by year, and whether "Tissue Inhibitor of Metalloproteinase-2" was a major or minor topic of these publication.