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Marilyn Brown

TitleProfessor of Clinical
InstitutionSchool of Medicine and Dentistry
DepartmentPediatrics
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 667
Rochester NY 14642
 
 Awards And Honors
2004     Ruth A Lawrence Faculty Service Award  | University of Rochester
2005     Rochester Academy of Medicine Award of Merit  | University of Rochester
2007 - 2013Best Doctors in America
2010     Cambridge Who's Who
2013     Albert Kaiser Medal of the Rochester Academy of Medicine
 
 Overview
Dr. Brown's primary research interest is Parenteral Nutrition.

Prokinetic agents in the treatment of gastroesophageal reflux in premature infants with Abhay Bhatt MD, Robert Sinkin MD, and Ronnie Guillet MD, 1998.

Limited Access Protocol for the Use of Oral Cisapride in the Treatment of Pediatric Patients with Refractory Gastroesophageal Reflux Disease and other Gastrointestinal Motility Disorders with Thomas M Rossi MD, 1999-2009.

3rd Generation Low Profile Balloon Gastrostomy Tube Insertion, Removal and Performance Study with Ross Products Division of Abbott Laboratories. Marilyn R. Brown with TM Rossi, TL Miller and RE Quiros 2001-2.

An open label, randomized, multiple dose, parallel multicenter study of Axid (Nizatidine) in the treatment of gastroesophageal reflux symptoms in pediatric subjects age 5days –18 years. Reliant Pharmaceuticals. Tracie L.Miller, Marilyn R. Brown. 2001.

Phase 3 double-masked, placebo-controlled study of alicaforsen (ISIS 2302), an Antisense Inhibitor of ICAM-1, for the treatment of patients with active Crohn's disease. ISIS Pharmaceuticals. Tracie L.Miller, Marilyn R. Brown, 2002.

A Phase II, Multi-Center, Open-Label Long-Term Study of the Safety Tolerability and Effectiveness of Intravenous antergren (natalizumab) in Adolescent Crohn's Disease. ELAN Pharmaceuticals. Tracie L. Miller, Brown MR. Completed 2005.

Pathways of differentiation of blood mononuclear cells in children with inflammatory bowel disease with Christopher Ritchlin, Juan Villalona, Cary Qualia, Marilyn R. Brown,Thomas Rossi, Koorosh Kooros and Natalie Sikka. IRB approved 05, several patients studied.

Brown MR, Nicchitta, J. Healthy habit goals for elevated body mass index: A program for the PCP. Tested in three Pediatric offices. Review done, Summer 2006.

Duration of pancreatic enzyme elevation in acute pancreatitis. Cary Qualia, Thomas Rossi, Brown MR, Asad Ullah. IRB approval 3/07

Specificity of the polyclonal antibody test system for human elastase-1 in stool in Cystic Fibrosis. Villalona J, Qualia C, Brown MR, Ren CL, Rossi T,. Data collection completed 3/07. Dr. Villalona writing up.

Eosinophilic Esophagitis in children: A retrospective review. Villalona, J, Brown MR, Rossi, TR, Katzman,P, Mathur, J. Finished in spring 06, waiting for Juan Villalona to finish the manuscript.

Evaluation of esophageal mucosa for filaggrin expression in patients with eosinophilic esophagitis. Qualia, C, Brown MR, Lisa Beck, Rossi, TR. Letter to Journal of Allergy and Clinical Immunology by Dr. Beck.

Review of Bravo pH studies in the Golisano Children's Hospital @ Strong Pediatric GI practice. Wahaj Zaidi, Thomas Rossi, Marilyn R. Brown. Poster In progress.

A phase 3, multi-center, randomized study to evaluate the safety, efficacy and pharmokinetics of the Human Anti-TNF Monoclonal antibody Adalimumab in pediatric subjects with moderate to severe Crohn's disease. Abbott Laboratories. Marilyn R. Brown. 2007-2009.

Hepatic portal eosinophilia in an adolescent girl taking tacrolimus after liver transplantation. Rene P. Myers, Anne B.Fender, Marilyn R. Brown, Charlotte K Ryan. Submitted to Pediatric Transplantation, August 2007, rejected

Choledochal cysts in children: Experience in New Delhi, India. Deepak Sobti, Devendra Gupta, Marilyn R. Brown. Poster presentation at Annual Poster Session of the Department of Pediatrics, October 2007.

Microarray analysis of peripheral blood and tissues of patients with immunemediated inflammatory diseases. Christopher Ritchlin, Edward Schwartz and others. IRB approval 6/07.

2007-present Co-Investigator, Autism Treatment Network: University of Rochester
ATN-INV-07-16. Principal investigator, Susan Hyman, MD. (Total direct costs: $150,000/yr x 3 yrs)

Koorosh Kooros, Heidi Connelly, Susan Hyman, Marilyn R. Brown. Sleep Studies with gastroesophageal reflux studies in children with autism spectrum disorder, 2010.

 
 Selected Publications
List All   |   Timeline
  1. Mallah HS, Brown MR, Rossi TM, Block RC. Parenteral fish oil-associated burr cell anemia. J Pediatr. 2010 Feb; 156(2):324-6.e1.
    View in: PubMed
  2. Qualia CM, Baldwin CD, Rossi TM, Wang H, Brown MR. Pediatric gastroenterology fellows, class of 2007: how well are they prepared for the future? J Pediatr Gastroenterol Nutr. 2008 Sep; 47(3):327-33.
    View in: PubMed
  3. Qualia CM, Katzman PJ, Brown MR, Kooros K. A report of two children with Helicobacter heilmannii gastritis and review of the literature. Pediatr Dev Pathol. 2007 Sep-Oct; 10(5):391-4.
    View in: PubMed
  4. Qualia CM, Brown MR, Leung AK, Robson WL, Janner D, Zouros A, McClure C, Wycliffe N, Barron S. Index of suspicion. Pediatr Rev. 2007 May; 28(5):193-8.
    View in: PubMed
  5. Qualia CM, Brown MR, Ryan CK, Rossi TM. Oral Mucosal Neuromas Leading to the Diagnosis of Multiple Endocrine Neoplasia Type 2B in a Child With Intestinal Pseudo-obstruction. Gastroenterol Hepatol (N Y). 2007 Mar; 3(3):208-11.
    View in: PubMed
  6. Teitelbaum DH, Tracy TF, Aouthmany MM, Llanos A, Brown MB, Yu S, Brown MR, Shulman RJ, Hirschl RB, Derusso PA, Cox J, Dahlgren J, Groner JI, Strouse PJ. Use of cholecystokinin-octapeptide for the prevention of parenteral nutrition-associated cholestasis. Pediatrics. 2005 May; 115(5):1332-40.
    View in: PubMed
  7. Korones DN, Brown MR, Palis J. "Liver function tests" are not always tests of liver function. Am J Hematol. 2001 Jan; 66(1):46-8.
    View in: PubMed
  8. Siafakas CG, Ryan CK, Brown MR, Miller TL. Multiple esophageal rings: an association with eosinophilic esophagitis: case report and review of the literature. Am J Gastroenterol. 2000 Jun; 95(6):1572-5.
    View in: PubMed
  9. Siafakas CG, Brown MR, Miller TL. Neonatal pancreatitis associated with familial lipoprotein lipase deficiency. J Pediatr Gastroenterol Nutr. 1999 Jul; 29(1):95-8.
    View in: PubMed
  10. Siafakas CG, Miller TL, Brown MR. Image of the month. Esophageal and rectosigmoid ulcers. Gastroenterology. 1998 Dec; 115(6):1316, 1616.
    View in: PubMed
  11. Riepenhoff-Talty M, Gouvea V, Evans MJ, Svensson L, Hoffenberg E, Sokol RJ, Uhnoo I, Greenberg SJ, Schäkel K, Zhaori G, Fitzgerald J, Chong S, el-Yousef M, Nemeth A, Brown M, Piccoli D, Hyams J, Ruffin D, Rossi T. Detection of group C rotavirus in infants with extrahepatic biliary atresia. J Infect Dis. 1996 Jul; 174(1):8-15.
    View in: PubMed
  12. Nakada SY, Brown MR, Rabinowitz R. Wilson's disease presenting as symptomatic urolithiasis: a case report and review of the literature. J Urol. 1994 Sep; 152(3):978-9.
    View in: PubMed
  13. Goldstein B, Brown MR, Hulbert WC, Rabinowitz R. Hyperammonemic encephalopathy secondary to diphtheroid urinary tract infection in a patient with prune belly syndrome. Crit Care Med. 1991 Apr; 19(4):578-86.
    View in: PubMed
  14. Alonso EM, Zdunek TM, Brown MR, Yousefzadeh DK, Whitington PF. Fibroinflammatory tumor of the liver causing biliary cirrhosis in an infant. J Pediatr Gastroenterol Nutr. 1991 Feb; 12(2):283-7.
    View in: PubMed
  15. Brown MR, Thunberg BJ, Golub L, Maniscalco WM, Cox C, Shapiro DL. Decreased cholestasis with enteral instead of intravenous protein in the very low-birth-weight infant. J Pediatr Gastroenterol Nutr. 1989 Jul; 9(1):21-7.
    View in: PubMed
  16. Forbes GB, Brown MR. Energy need for weight maintenance in human beings: effect of body size and composition. J Am Diet Assoc. 1989 Apr; 89(4):499-502.
    View in: PubMed
  17. Forbes GB, Brown MR, Welle SL, Underwood LE. Hormonal response to overfeeding. Am J Clin Nutr. 1989 Apr; 49(4):608-11.
    View in: PubMed
  18. Pearson RD, Swenson I, Schenk EA, Klish WJ, Brown MR. Fatal multisystem disease with immune enteropathy heralded by juvenile rheumatoid arthritis. J Pediatr Gastroenterol Nutr. 1989 Feb; 8(2):259-65.
    View in: PubMed
  19. Cohen HJ, Brown MR, Hamilton D, Lyons-Patterson J, Avissar N, Liegey P. Glutathione peroxidase and selenium deficiency in patients receiving home parenteral nutrition: time course for development of deficiency and repletion of enzyme activity in plasma and blood cells. Am J Clin Nutr. 1989 Jan; 49(1):132-9.
    View in: PubMed
  20. Forbes GB, Brown MR, Griffiths HJ. Arm muscle plus bone area: anthropometry and CAT scan compared. Am J Clin Nutr. 1988 Jun; 47(6):929-31.
    View in: PubMed
  21. Forbes GB, Brown MR, Welle SL, Lipinski BA. Deliberate overfeeding in women and men: energy cost and composition of the weight gain. Br J Nutr. 1986 Jul; 56(1):1-9.
    View in: PubMed
  22. Brown MR, Cohen HJ, Lyons JM, Curtis TW, Thunberg B, Cochran WJ, Klish WJ. Proximal muscle weakness and selenium deficiency associated with long term parenteral nutrition. Am J Clin Nutr. 1986 Apr; 43(4):549-54.
    View in: PubMed
  23. Cochran WJ, Klish WJ, Brown MR, Lyons JM, Curtis T. Chylous ascites in infants and children: a case report and literature review. J Pediatr Gastroenterol Nutr. 1985 Aug; 4(4):668-73.
    View in: PubMed
  24. Weinberg RJ, Tipton G, Klish WJ, Brown MR. Effect of breast-feeding on morbidity in rotavirus gastroenteritis. Pediatrics. 1984 Aug; 74(2):250-3.
    View in: PubMed
  25. Putnam TC, Lawrence RA, Wood BP, Campbell MA, Emmens RW, Brown MR, Klish WJ. Esophageal function after repair of esophageal atresia. Surg Gynecol Obstet. 1984 Apr; 158(4):344-8.
    View in: PubMed
  26. Brown MR, Klish WJ, Hollander J, Campbell MA, Forbes GB. A high protein, low calorie liquid diet in the treatment of very obese adolescents: long-term effect on lean body mass. Am J Clin Nutr. 1983 Jul; 38(1):20-31.
    View in: PubMed
  27. Patton ML, Brown MR, Lewis A, Baran DT. Body weight and its effect on immunoreactive parathyroid hormone levels. Miner Electrolyte Metab. 1983; 9(3):151-3.
    View in: PubMed
  28. Weinberg RJ, Klish WJ, Brown MR, Smalley JR, Emmens RW. Hepatic abscess as a complication of Crohn's disease. J Pediatr Gastroenterol Nutr. 1983; 2(1):171-4.
    View in: PubMed
  29. Weinberg RJ, Klish WJ, Smalley JR, Brown MR, Putnam TC. Acquired distal aganglionosis of the colon. J Pediatr. 1982 Sep; 101(3):406-9.
    View in: PubMed
  30. Smalley JR, Klish WJ, Brown MR, Campbell MA. Chronic diarrhea associated with campylobacter. Clin Pediatr (Phila). 1982 Apr; 21(4):220.
    View in: PubMed
  31. Smalley JR, Klish WJ, Campbell MA, Brown MR. Use of psyllium in the management of chronic nonspecific diarrhea of childhood. J Pediatr Gastroenterol Nutr. 1982; 1(3):361-3.
    View in: PubMed
  32. Brown MR, Gordon A, Campbell MA, Chey WY. Milk meal in children; gastrin response. N Y State J Med. 1980 Oct; 80(11):1681-3.
    View in: PubMed
  33. Enck RE, Betts RF, Brown MR, Miller G. Viral serology (hepatitis B virus, cytomegalovirus, Epstein-Barr virus) and abnormal liver function tests in transfused patients with hereditary hemorrhagic diseases. Transfusion. 1979 Jan-Feb; 19(1):32-8.
    View in: PubMed
  34. Brown MR, Putnam TC. Cholestasis associated with central intravenous nutrition in infants. N Y State J Med. 1978 Jan; 78(1):27-30.
    View in: PubMed
  35. Failure of specific immunotherapy in fulminant type B hepatitis. Ann Intern Med. 1977 Mar; 86(3):272-7.
    View in: PubMed
  36. Mangla JC, Kim YM, Brown MR, Schwob D, Hanson SE. Liver tests, HB-Ag and HB-Ab in asymptomatic drug addicts. Am J Gastroenterol. 1976 Feb; 65(2):121-6.
    View in: PubMed
  37. Brown MR, Lillibridge CB. When to think of celiac disease: the classical features of gluten sensitive enteropathy are absent. Clin Pediatr (Phila). 1975 Jan; 14(1):76-82.
    View in: PubMed
  38. Lillibridge CB, Brown MR, Hall JG. The electron microscopic appearance of presecreted gastric mucus in cystic fibrosis. Pediatrics. 1974 Jun; 53(6):913-9.
    View in: PubMed

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