Louis Constine
| Title | Professor |
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| Institution | School of Medicine and Dentistry |
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| Department | Radiation Oncology |
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| Address | University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 647
Rochester NY 14642
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| 1969 |
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| Beta Kappa | | 1969 |
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| Graduation with Distinction | | 1983 |
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| Teddy Award | | 1983 |
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| 1986 | Junior Faculty Fellowship Award | | 1997 |
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| Philip Rubin-Mayer Mitchell Teaching Award | | 2001 |
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| Jacob Gitelman Award | | 2001 |
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| Philip Rubin-Mayer Mitchell Teaching Award | | 2004 |
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| Ring of Fire Award | | 2005 |
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| Philip Rubin-Mayer Mitchell Teaching Award | | 2007 |
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| America's Top Doctors for Cancer | America's Best Doctors | | 2007 |
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| 2008 | Best Doctor | BestDoctors.com | | 2008 |
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| Fellow of the American Society for Therapeutic Radiology and Oncology (FASTRO) | | 2008 |
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| Make a Difference Award | Melissa's Living Legacy Teen Cancer Foundation | | 2010 |
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| Merit Award: PDQ Pediatric Treatment Editorial Board | National Institutes of Health | | 2011 |
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| Educator of the Year | Association of Residents in Radiation Oncology |
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Padovani L, André N, Constine LS, Muracciole X. Neurocognitive function after radiotherapy for paediatric brain tumours. Nat Rev Neurol. 2012 Sep 11; 8(10):578-88.
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Youn P, Li H, Milano MT, Stovall M, Constine LS, Travis LB. Long-term survival among Hodgkin's lymphoma patients with gastrointestinal cancer: a population-based study. Ann Oncol. 2013 Jan; 24(1):202-8.
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Henderson TO, Rajaraman P, Stovall M, Constine LS, Olive A, Smith SA, Mertens A, Meadows A, Neglia JP, Hammond S, Whitton J, Inskip PD, Robison LL, Diller L. Risk factors associated with secondary sarcomas in childhood cancer survivors: a report from the childhood cancer survivor study. Int J Radiat Oncol Biol Phys. 2012 Sep 1; 84(1):224-30.
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Voss SD, Chen L, Constine LS, Chauvenet A, Fitzgerald TJ, Kaste SC, Slovis T, Schwartz CL. Surveillance Computed Tomography Imaging and Detection of Relapse in Intermediate- and Advanced-Stage Pediatric Hodgkin's Lymphoma: A Report From the Children's Oncology Group. J Clin Oncol. 2012 Jul 20; 30(21):2635-40.
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Henderson TO, Oeffinger KC, Whitton J, Leisenring W, Neglia J, Meadows A, Crotty C, Rubin DT, Diller L, Inskip P, Smith SA, Stovall M, Constine LS, Hammond S, Armstrong GT, Robison LL, Nathan PC. Secondary gastrointestinal cancer in childhood cancer survivors: a cohort study. Ann Intern Med. 2012 Jun 5; 156(11):757-66.
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Kenney LB, Cohen LE, Shnorhavorian M, Metzger ML, Lockart B, Hijiya N, Duffey-Lind E, Constine L, Green D, Meacham L. Male Reproductive Health After Childhood, Adolescent, and Young Adult Cancers: A Report From the Children's Oncology Group. J Clin Oncol. 2012 Sep 20; 30(27):3408-16.
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Biswas T, Culakova E, Friedberg JW, Kelly JL, Dhakal S, Liesveld J, Phillips GL, Constine LS. Involved field radiation therapy following high dose chemotherapy and autologous stem cell transplant benefits local control and survival in refractory or recurrent Hodgkin lymphoma. Radiother Oncol. 2012 Jun; 103(3):367-72.
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Lipshultz SE, Landy DC, Lopez-Mitnik G, Lipsitz SR, Hinkle AS, Constine LS, French CA, Rovitelli AM, Proukou C, Adams MJ, Miller TL. Cardiovascular status of childhood cancer survivors exposed and unexposed to cardiotoxic therapy. J Clin Oncol. 2012 Apr 1; 30(10):1050-7.
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Travis LB, Ng AK, Allan JM, Pui CH, Kennedy AR, Xu XG, Purdy JA, Applegate K, Yahalom J, Constine LS, Gilbert ES, Boice JD. Second malignant neoplasms and cardiovascular disease following radiotherapy. J Natl Cancer Inst. 2012 Mar 7; 104(5):357-70.
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Landy DC, Miller TL, Lopez-Mitnik G, Lipsitz SR, Hinkle AS, Constine LS, French CA, Rovitelli AM, Adams MJ, Lipshultz SE. Aggregating traditional cardiovascular disease risk factors to assess the cardiometabolic health of childhood cancer survivors: An analysis from the Cardiac Risk Factors in Childhood Cancer Survivors Study. Am Heart J. 2012 Feb; 163(2):295-301.e2.
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Milano MT, Li H, Constine LS, Travis LB. Variables affecting survival after second primary lung cancer: A population-based study of 187 Hodgkin's lymphoma patients. J Thorac Dis. 2012 Feb; 4(1):22-9.
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Chawla S, Korones DN, Milano MT, Hussain A, Hussien AR, Muhs AG, Mangla M, Silberstein H, Ekholm S, Constine LS. Spurious progression in pediatric brain tumors. J Neurooncol. 2012 May; 107(3):651-7.
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Ban-Hoefen M, Kelly JL, Bernstein SH, Liesveld J, Constine L, Becker M, Milner L, Phillips G, Friedberg JW. High-dose therapy and autologous stem cell transplant for transformed non-Hodgkin lymphoma in the rituximab era. Leuk Lymphoma. 2012 May; 53(5):830-5.
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Keller SF, Kelly JL, Sensenig E, Andreozzi J, Oliva J, Rich L, Constine L, Becker M, Phillips G, Liesveld J, Fisher RI, Bernstein SH, Friedberg JW. Late Relapses following High-Dose Autologous Stem Cell Transplantation (HD-ASCT) for Hodgkin's Lymphoma (HL) in the ABVD Therapeutic Era. Biol Blood Marrow Transplant. 2012 Apr; 18(4):640-7.
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Bredlau AL, Constine LS, Silberstein HJ, Milano MT, Korones DN. Incidental brain lesions in children: to treat or not to treat? J Neurooncol. 2012 Feb; 106(3):589-94.
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Milano MT, Li H, Constine LS, Travis LB. Survival after second primary lung cancer: A population-based study of 187 Hodgkin lymphoma patients. Cancer. 2011 Dec 15; 117(24):5538-47.
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Elkin EB, Klem ML, Gonzales AM, Ishill NM, Hodgson D, Ng AK, Marks LB, Weidhaas J, Freedman GM, Miller RC, Constine LS, Myrehaug S, Yahalom J. Characteristics and outcomes of breast cancer in women with and without a history of radiation for Hodgkin's lymphoma: a multi-institutional, matched cohort study. J Clin Oncol. 2011 Jun 20; 29(18):2466-73.
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Das P, Ng A, Constine LS, Advani R, Flowers C, Friedberg J, Hodgson DC, Schwartz CL, Wilder RB, Wilson LD, Yunes MJ. ACR Appropriateness Criteria® on Hodgkin's lymphoma-unfavorable clinical stage I and II. J Am Coll Radiol. 2011 May; 8(5):302-8.
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Dhakal S, Corbin KS, Milano MT, Philip A, Sahasrabudhe D, Jones C, Constine LS. Stereotactic body radiotherapy for pulmonary metastases from soft-tissue sarcomas: excellent local lesion control and improved patient survival. Int J Radiat Oncol Biol Phys. 2012 Feb 1; 82(2):940-5.
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Phillips GL, Bernstein SH, Liesveld JL, Abboud CN, Becker MW, Constine LS, Ifthikharuddin JJ, Loughner JE, Milner LA, Vesole DH, Friedberg JW. A Phase I trial: dose escalation of melphalan in the "BEAM" regimen using amifostine cytoprotection. Biol Blood Marrow Transplant. 2011 Jul; 17(7):1033-42.
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Adams MJ, Shore RE, Dozier A, Lipshultz SE, Schwartz RG, Constine LS, Pearson TA, Stovall M, Thevenet-Morrison K, Fisher SG. Thyroid cancer risk 40+ years after irradiation for an enlarged thymus: an update of the Hempelmann cohort. Radiat Res. 2010 Dec; 174(6):753-62.
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Milano MT, Li H, Gail MH, Constine LS, Travis LB. Long-term survival among patients with Hodgkin's lymphoma who developed breast cancer: a population-based study. J Clin Oncol. 2010 Dec 1; 28(34):5088-96.
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Dhakal S, Chen J, McCance S, Rosier R, O'Keefe R, Constine LS. Bone density changes after radiation for extremity sarcomas: exploring the etiology of pathologic fractures. Int J Radiat Oncol Biol Phys. 2011 Jul 15; 80(4):1158-63.
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Miller TL, Lipsitz SR, Lopez-Mitnik G, Hinkle AS, Constine LS, Adams MJ, French C, Proukou C, Rovitelli A, Lipshultz SE. Characteristics and determinants of adiposity in pediatric cancer survivors. Cancer Epidemiol Biomarkers Prev. 2010 Aug; 19(8):2013-22.
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Travis LB, Beard C, Allan JM, Dahl AA, Feldman DR, Oldenburg J, Daugaard G, Kelly JL, Dolan ME, Hannigan R, Constine LS, Oeffinger KC, Okunieff P, Armstrong G, Wiljer D, Miller RC, Gietema JA, van Leeuwen FE, Williams JP, Nichols CR, Einhorn LH, Fossa SD. Testicular cancer survivorship: research strategies and recommendations. J Natl Cancer Inst. 2010 Aug 4; 102(15):1114-30.
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Ng A, Constine LS, Advani R, Das P, Flowers C, Friedberg J, Hodgson DC, Schwartz CL, Wilder RB, Wilson LD, Yunes MJ. ACR Appropriateness Criteria: follow-up of Hodgkin's lymphoma. Curr Probl Cancer. 2010 May-Jun; 34(3):211-27.
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Fitzgerald TJ, Bishop-Jodoin M, Cicchetti MG, Hanusik R, Kessel S, Laurie F, McCarten KM, Moni J, Pieters RS, Rosen N, Ulin K, Urie M, Chauvenet AR, Constine LS, Deye J, Vikram B, Friedman D, Marcus RB, Mendenhall NP, Williams JL, Purdy J, Saltz J, Schwartz CL, White KS, Wolden S. Quality of radiotherapy reporting in randomized controlled trials of Hodgkin's lymphoma and non-Hodgkin's lymphoma: in regard to Bekelman and Yahalom (Int J Radiat Oncol Biol Phys 2009;73:492-498). Int J Radiat Oncol Biol Phys. 2010 May 1; 77(1):315-6.
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Henderson TO, Amsterdam A, Bhatia S, Hudson MM, Meadows AT, Neglia JP, Diller LR, Constine LS, Smith RA, Mahoney MC, Morris EA, Montgomery LL, Landier W, Smith SM, Robison LL, Oeffinger KC. Systematic review: surveillance for breast cancer in women treated with chest radiation for childhood, adolescent, or young adult cancer. Ann Intern Med. 2010 Apr 6; 152(7):444-55; W144-54.
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Marks LB, Yorke ED, Jackson A, Ten Haken RK, Constine LS, Eisbruch A, Bentzen SM, Nam J, Deasy JO. Use of normal tissue complication probability models in the clinic. Int J Radiat Oncol Biol Phys. 2010 Mar 1; 76(3 Suppl):S10-9.
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Deasy JO, Bentzen SM, Jackson A, Ten Haken RK, Yorke ED, Constine LS, Sharma A, Marks LB. Improving normal tissue complication probability models: the need to adopt a "data-pooling" culture. Int J Radiat Oncol Biol Phys. 2010 Mar 1; 76(3 Suppl):S151-4.
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Darby SC, Cutter DJ, Boerma M, Constine LS, Fajardo LF, Kodama K, Mabuchi K, Marks LB, Mettler FA, Pierce LJ, Trott KR, Yeh ET, Shore RE. Radiation-related heart disease: current knowledge and future prospects. Int J Radiat Oncol Biol Phys. 2010 Mar 1; 76(3):656-65.
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Jackson A, Marks LB, Bentzen SM, Eisbruch A, Yorke ED, Ten Haken RK, Constine LS, Deasy JO. The lessons of QUANTEC: recommendations for reporting and gathering data on dose-volume dependencies of treatment outcome. Int J Radiat Oncol Biol Phys. 2010 Mar 1; 76(3 Suppl):S155-60.
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Bentzen SM, Constine LS, Deasy JO, Eisbruch A, Jackson A, Marks LB, Ten Haken RK, Yorke ED. Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): an introduction to the scientific issues. Int J Radiat Oncol Biol Phys. 2010 Mar 1; 76(3 Suppl):S3-9.
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Gagliardi G, Constine LS, Moiseenko V, Correa C, Pierce LJ, Allen AM, Marks LB. Radiation dose-volume effects in the heart. Int J Radiat Oncol Biol Phys. 2010 Mar 1; 76(3 Suppl):S77-85.
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Constine LS. Introduction: The ageless quest to understand aging, but with a malignant twist. Semin Radiat Oncol. 2010 Jan; 20(1):1-2.
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Rubin P, Williams JP, Devesa SS, Travis LB, Constine LS. Cancer genesis across the age spectrum: associations with tissue development, maintenance, and senescence. Semin Radiat Oncol. 2010 Jan; 20(1):3-11.
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Krasin MJ, Constine LS, Friedman DL, Marks LB. Radiation-related treatment effects across the age spectrum: differences and similarities or what the old and young can learn from each other. Semin Radiat Oncol. 2010 Jan; 20(1):21-9.
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Paulino AC, Constine LS, Rubin P, Williams JP. Normal tissue development, homeostasis, senescence, and the sensitivity to radiation injury across the age spectrum. Semin Radiat Oncol. 2010 Jan; 20(1):12-20.
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Adams MJ, Dozier A, Shore RE, Lipshultz SE, Schwartz RG, Constine LS, Pearson TA, Stovall M, Winters P, Fisher SG. Breast cancer risk 55+ years after irradiation for an enlarged thymus and its implications for early childhood medical irradiation today. Cancer Epidemiol Biomarkers Prev. 2010 Jan; 19(1):48-58.
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Okunieff P, Kachnic LA, Constine LS, Fuller CD, Gaspar LE, Hayes DF, Hooks J, Ling C, Meyskens FL, Philip PA, Raben D, Smalley SR, Swanson GP, Teicher BA, Thomas CR, Vikram B, Zelefsky MJ, Baker LH. Report from the Radiation Therapy Committee of the Southwest Oncology Group (SWOG): Research Objectives Workshop 2008. Clin Cancer Res. 2009 Sep 15; 15(18):5663-70.
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Biswas T, Dhakal S, Chen R, Hyrien O, Bernstein S, Friedberg JW, Fisher RI, Liesveld J, Phillips G, Constine LS. Involved field radiation after autologous stem cell transplant for diffuse large B-cell lymphoma in the rituximab era. Int J Radiat Oncol Biol Phys. 2010 May 1; 77(1):79-85.
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Schwartz CL, Constine LS, Villaluna D, London WB, Hutchison RE, Sposto R, Lipshultz SE, Turner CS, deAlarcon PA, Chauvenet A. A risk-adapted, response-based approach using ABVE-PC for children and adolescents with intermediate- and high-risk Hodgkin lymphoma: the results of P9425. Blood. 2009 Sep 3; 114(10):2051-9.
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Bhatia S, Constine LS. Late morbidity after successful treatment of children with cancer. Cancer J. 2009 May-Jun; 15(3):174-80.
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Dhakal S, Biswas T, Liesveld JL, Friedberg JW, Phillips GL, Constine LS. Patterns and timing of initial relapse in patients subsequently undergoing transplantation for Hodgkin's lymphoma. Int J Radiat Oncol Biol Phys. 2009 Sep 1; 75(1):188-92.
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Milano MT, Constine LS, Okunieff P. Normal tissue toxicity after small field hypofractionated stereotactic body radiation. Radiat Oncol. 2008; 3:36.
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Das P, Ng A, Constine LS, Hodgson DC, Mendenhall NP, Morris DE, Yunes MJ, Chauvenet AR, Hudson MM, Winter JN. ACR Appropriateness Criteria on Hodgkin's lymphoma: favorable prognosis stage I and II. J Am Coll Radiol. 2008 Oct; 5(10):1054-66.
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Constine LS, Tarbell N, Hudson MM, Schwartz C, Fisher SG, Muhs AG, Basu SK, Kun LE, Ng A, Mauch P, Sandhu A, Culakova E, Lyman G, Mendenhall N. Subsequent malignancies in children treated for Hodgkin's disease: associations with gender and radiation dose. Int J Radiat Oncol Biol Phys. 2008 Sep 1; 72(1):24-33.
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Basu SK, Schwartz C, Fisher SG, Hudson MM, Tarbell N, Muhs A, Marcus KJ, Mendenhall N, Mauch P, Kun LE, Constine LS. Unilateral and bilateral breast cancer in women surviving pediatric Hodgkin's disease. Int J Radiat Oncol Biol Phys. 2008 Sep 1; 72(1):34-40.
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Constine LS. Cured of Hodgkin lymphoma, but suffering a broken heart. Leuk Lymphoma. 2008 Aug; 49(8):1433-5.
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Corbin K, Fisher S, Sahasrabudhe D, Pandya K, Brasacchio R, Constine LS. Five tumors over six years in eighth decade of life. Cancer Invest. 2008 Jul; 26(6):634-7.
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Bylund KC, Giampoli E, Singh D, Doerr T, Sahasrabudhe D, Liesveld J, Constine LS. Soft tissue sarcoma in the setting of chronic cutaneous graft versus host disease after allogenic bone marrow transplantation. Cancer Invest. 2008 Jul; 26(6):638-41.
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Hodgson DC, Hudson MM, Constine LS. Pediatric hodgkin lymphoma: maximizing efficacy and minimizing toxicity. Semin Radiat Oncol. 2007 Jul; 17(3):230-42.
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Adams MJ, Constine LS, Lipshultz SE. Late effects of therapy for Hodgkin's lymphoma. Curr Hematol Malig Rep. 2007 Jul; 2(3):143-50.
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Milano MT, Constine LS, Okunieff P. Normal tissue tolerance dose metrics for radiation therapy of major organs. Semin Radiat Oncol. 2007 Apr; 17(2):131-40.
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Tebbi CK, London WB, Friedman D, Villaluna D, De Alarcon PA, Constine LS, Mendenhall NP, Sposto R, Chauvenet A, Schwartz CL. Dexrazoxane-associated risk for acute myeloid leukemia/myelodysplastic syndrome and other secondary malignancies in pediatric Hodgkin's disease. J Clin Oncol. 2007 Feb 10; 25(5):493-500.
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Alvarez JA, Scully RE, Miller TL, Armstrong FD, Constine LS, Friedman DL, Lipshultz SE. Long-term effects of treatments for childhood cancers. Curr Opin Pediatr. 2007 Feb; 19(1):23-31.
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Deeg HJ, Friedman D, Bohr VA, Constine L, Jones IM, Sigurdson A, Socié G, Van Zant G, Wei Q, Martin P. Transplantation and aging. Biol Blood Marrow Transplant. 2006 Sep; 12(9):893-8.
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Carey Sampson M, Katz A, Constine LS. Stereotactic body radiation therapy for extracranial oligometastases: does the sword have a double edge? Semin Radiat Oncol. 2006 Apr; 16(2):67-76.
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Friedman DL, Constine LS. Late effects of treatment for Hodgkin lymphoma. J Natl Compr Canc Netw. 2006 Mar; 4(3):249-57.
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Mauch P, Ng A, Aleman B, Carde P, Constine L, Diehl V, Dinshaw K, Gospodarowicz M, Hancock S, Hodgson D, Hoppe R, Liang R, Loeffler M, Specht L, Travis LB, Wirth A, Yahalom J. Report from the Rockefellar Foundation Sponsored International Workshop on reducing mortality and improving quality of life in long-term survivors of Hodgkin's disease: July 9-16, 2003, Bellagio, Italy. Eur J Haematol Suppl. 2005 Jul; (66):68-76.
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Landier W, Bhatia S, Eshelman DA, Forte KJ, Sweeney T, Hester AL, Darling J, Armstrong FD, Blatt J, Constine LS, Freeman CR, Friedman DL, Green DM, Marina N, Meadows AT, Neglia JP, Oeffinger KC, Robison LL, Ruccione KS, Sklar CA, Hudson MM. Development of risk-based guidelines for pediatric cancer survivors: the Children's Oncology Group Long-Term Follow-Up Guidelines from the Children's Oncology Group Late Effects Committee and Nursing Discipline. J Clin Oncol. 2004 Dec 15; 22(24):4979-90.
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Hinkle AS, Proukou C, French CA, Kozlowski AM, Constine LS, Lipsitz SR, Miller TL, Lipshultz SE. A clinic-based, comprehensive care model for studying late effects in long-term survivors of pediatric illnesses. Pediatrics. 2004 Apr; 113(4 Suppl):1141-5.
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Adams MJ, Lipshultz SE, Schwartz C, Fajardo LF, Coen V, Constine LS. Radiation-associated cardiovascular disease: manifestations and management. Semin Radiat Oncol. 2003 Jul; 13(3):346-56.
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Korones DN, Padowski J, Factor BA, Constine LS. Do children with optic pathway tumors have an increased frequency of other central nervous system tumors? Neuro Oncol. 2003 Apr; 5(2):116-20.
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Adams MJ, Hardenbergh PH, Constine LS, Lipshultz SE. Radiation-associated cardiovascular disease. Crit Rev Oncol Hematol. 2003 Jan; 45(1):55-75.
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Pateder DB, Sheu TJ, O'Keefe RJ, Puzas JE, Schwarz EM, Constine LS, Okunieff P, Rosier RN. Role of pentoxifylline in preventing radiation damage to epiphyseal growth plate chondrocytes. Radiat Res. 2002 Jan; 157(1):62-8.
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Pateder DB, Eliseev RA, O'Keefe RJ, Schwarz EM, Okunieff P, Constine LS, Puzas JE, Rosier RN. The role of autocrine growth factors in radiation damage to the epiphyseal growth plate. Radiat Res. 2001 Jun; 155(6):847-57.
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Korones DN, Butterfield R, Meyers SP, Constine LS. The role of surveillance magnetic resonance imaging (MRI) scanning in detecting recurrent brain tumors in asymptomatic children. J Neurooncol. 2001 May; 53(1):33-8.
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Sandhu A, Constine LS, O'Mara RE, Hinkle A, Muhs AG, Woolf PD. Subclinical thyroid disease after radiation therapy detected by radionuclide scanning. Int J Radiat Oncol Biol Phys. 2000 Aug 1; 48(1):181-8.
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Constine LS, Wolkov HB, Yahalom J, Mauch PM, Deming RL, Dosoretz DE, Elman AJ, Hoppe RT, Pistenmaa DA, Prosnitz LR, Chauvenet A, Connors JM, Glick JH, Leibel S. Pediatric Hodgkin's disease. American College of Radiology. ACR Appropriateness Criteria. Radiology. 2000 Jun; 215 Suppl:1225-56.
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Deming RL, Constine LS, Elman AJ, Hoppe RT, Mauch PM, Dosoretz DE, Pistenmaa DA, Prosnitz LR, Wolkov HB, Yahalom J, Chauvenet A, Connors JM, Glick JH, Leibel S. Follow-up of Hodgkin's disease. American College of Radiology. ACR Appropriateness Criteria. Radiology. 2000 Jun; 215 Suppl:1269-79.
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Wolkov HB, Elman AJ, Hoppe RT, Pistenmaa DA, Mauch PM, Constine LS, Deming RL, Dosoretz DE, Prosnitz LR, Yahalom J, Chauvenet A, Connors JM, Glick JH, Leibel S. Staging evaluation for patients with Hodgkin's disease. American College of Radiology. ACR Appropriateness Criteria. Radiology. 2000 Jun; 215 Suppl:1207-23.
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Prosnitz LR, Connors JM, Deming RL, Yahalom J, Mauch PM, Constine LS, Dosoretz DE, Elman AJ, Hoppe RT, Pistenmaa DA, Wolkov HB, Chauvenet A, Glick JH, Leibel S. Stage III and IV Hodgkin's disease treatment guidelines. American College of Radiology. ACR Appropriateness Criteria. Radiology. 2000 Jun; 215 Suppl:1257-68.
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Duerst RE, Horan JT, Liesveld JL, Abboud CN, Zwetsch LM, Senf ES, Constine LS, Raubertas RF, Passarell JA, DiPersio JF. Allogeneic bone marrow transplantation for children with acute leukemia: cytoreduction with fractionated total body irradiation, high-dose etoposide and cyclophosphamide. Bone Marrow Transplant. 2000 Mar; 25(5):489-94.
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Liesveld J, Duerst R, Rapoport A, Constine L, Abboud C, Packman C, Wedow L, Zwetsch L, McKenna B, Linder T, Silverman W, Swift S, Rowe J, DiPersio J. Continuous infusion cyclosporine and nifedipine to day +100 with short methotrexate and steroids as GVHD prophylaxis in unrelated donor transplants. Bone Marrow Transplant. 1999 Sep; 24(5):511-6.
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Rubin P, Constine LS. In response to Brock, IJROBP 43:473-474, 1999. Int J Radiat Oncol Biol Phys. 1999 Aug 1; 45(1):246-7.
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Rapoport AP, Miller Watelet LF, Linder T, Eberly S, Raubertas RF, Lipp J, Duerst R, Abboud CN, Constine L, Andrews J, Etter MA, Spear L, Powley E, Packman CH, Rowe JM, Schwertschlag U, Bedrosian C, Liesveld JL. Analysis of factors that correlate with mucositis in recipients of autologous and allogeneic stem-cell transplants. J Clin Oncol. 1999 Aug; 17(8):2446-53.
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Okunieff P, Barrett AJ, Phang SE, Li A, Constine LS, Williams JP, Rubin P, Wang X, Wu T, Chen Y, Ding I. Circulating basic fibroblast growth factor declines during Cy/TBI bone marrow transplantation. Bone Marrow Transplant. 1999 Jun; 23(11):1117-21.
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Korones DN, Meyers SP, Rubio A, Torres C, Constine LS. A 4-year-old girl with a ventriculoperitoneal shunt metastasis of a central nervous system atypical teratoid/rhabdoid tumor. Med Pediatr Oncol. 1999 May; 32(5):389-91.
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Okunieff P, Wang X, Rubin P, Finkelstein JN, Constine LS, Ding I. Radiation-induced changes in bone perfusion and angiogenesis. Int J Radiat Oncol Biol Phys. 1998 Nov 1; 42(4):885-9.
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Lancet JE, Rapoport AP, Brasacchio R, Eberly S, Raubertas RF, Linder T, Muhs A, Duerst RE, Abboud CN, Packman CH, DiPersio JF, Constine LS, Rowe JM, Liesveld JL. Autotransplantation for relapsed or refractory Hodgkin's disease: long-term follow-up and analysis of prognostic factors. Bone Marrow Transplant. 1998 Aug; 22(3):265-71.
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Rapoport AP, Constine LS, Packman CH, Rosier RN, O'Keefe R, Hicks DG, Rubin SJ, Rowe JM. Treatment of multifocal lymphoma of bone with intensified ProMACE-CytaBOM chemotherapy and involved field radiotherapy. Am J Hematol. 1998 May; 58(1):1-7.
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Karayalcin G, Behm FG, Gieser PW, Kung F, Weiner M, Tebbi CK, Ferree C, Marcus R, Constine L, Mendenhall NP, Chauvenet A, Murphy SB. Lymphocyte predominant Hodgkin disease: clinico-pathologic features and results of treatment--the Pediatric Oncology Group experience. Med Pediatr Oncol. 1997 Dec; 29(6):519-25.
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Constine LS, Schwartz RG, Savage DE, King V, Muhs A. Cardiac function, perfusion, and morbidity in irradiated long-term survivors of Hodgkin's disease. Int J Radiat Oncol Biol Phys. 1997 Nov 1; 39(4):897-906.
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Rapoport AP, Lifton R, Constine LS, Duerst RE, Abboud CN, Liesveld JL, Packman CH, Eberly S, Raubertas RF, Martin BA, Flesher WR, Kouides PA, DiPersio JF, Rowe JM. Autotransplantation for relapsed or refractory non-Hodgkin's lymphoma (NHL): long-term follow-up and analysis of prognostic factors. Bone Marrow Transplant. 1997 May; 19(9):883-90.
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Bieri S, Sklar C, Constine L, Bernier J. [Late effects of radiotherapy on the neuroendocrine system]. Cancer Radiother. 1997; 1(6):706-16.
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King V, Constine LS, Clark D, Schwartz RG, Muhs AG, Henzler M, Hutson A, Rubin P. Symptomatic coronary artery disease after mantle irradiation for Hodgkin's disease. Int J Radiat Oncol Biol Phys. 1996 Nov 1; 36(4):881-9.
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Constine LS, Rapoport AP. Hodgkin's disease, bone marrow transplantation, and involved field radiation therapy: coming full circle from 1902 to 1996. Int J Radiat Oncol Biol Phys. 1996 Aug 1; 36(1):253-5.
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Simpson JR, Scott CB, Rotman M, Curran WJ, Constine LS, Fischbach AJ, Asbell SO. Race and prognosis of brain tumor patients entering multicenter clinical trials. A report from the Radiation Therapy Oncology Group. Am J Clin Oncol. 1996 Apr; 19(2):114-20.
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Constine LS, Marcus RB, Halperin EC. The future of therapy for childhood rhabdomyosarcoma: clues from molecular biology. Int J Radiat Oncol Biol Phys. 1995 Jul 15; 32(4):1245-9; discussion 1263.
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Rubin P, Constine LS, Fajardo LF, Phillips TL, Wasserman TH. EORTC Late Effects Working Group. Overview of late effects normal tissues (LENT) scoring system. Radiother Oncol. 1995 Apr; 35(1):9-10.
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Rubin P, Constine LS, Fajardo LF, Phillips TL, Wasserman TH. RTOG Late Effects Working Group. Overview. Late Effects of Normal Tissues (LENT) scoring system. Int J Radiat Oncol Biol Phys. 1995 Mar 30; 31(5):1041-2.
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Hancock SL, McDougall IR, Constine LS. Thyroid abnormalities after therapeutic external radiation. Int J Radiat Oncol Biol Phys. 1995 Mar 30; 31(5):1165-70.
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Mauch P, Constine L, Greenberger J, Knospe W, Sullivan J, Liesveld JL, Deeg HJ. Hematopoietic stem cell compartment: acute and late effects of radiation therapy and chemotherapy. Int J Radiat Oncol Biol Phys. 1995 Mar 30; 31(5):1319-39.
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Sklar CA, Constine LS. Chronic neuroendocrinological sequelae of radiation therapy. Int J Radiat Oncol Biol Phys. 1995 Mar 30; 31(5):1113-21.
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Stewart JR, Fajardo LF, Gillette SM, Constine LS. Radiation injury to the heart. Int J Radiat Oncol Biol Phys. 1995 Mar 30; 31(5):1205-11.
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Constine LS. What else don't we know about the late effects of radiation in patients treated for head and neck cancer? Int J Radiat Oncol Biol Phys. 1995 Jan 15; 31(2):427-9.
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Schwartz CL, Hobbie WL, Truesdell S, Constine LC, Clark EB. Corrected QT interval prolongation in anthracycline-treated survivors of childhood cancer. J Clin Oncol. 1993 Oct; 11(10):1906-10.
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Nelson DF, Curran WJ, Scott C, Nelson JS, Weinstein AS, Ahmad K, Constine LS, Murray K, Powlis WD, Mohiuddin M, et al. Hyperfractionated radiation therapy and bis-chlorethyl nitrosourea in the treatment of malignant glioma--possible advantage observed at 72.0 Gy in 1.2 Gy B.I.D. fractions: report of the Radiation Therapy Oncology Group Protocol 8302. Int J Radiat Oncol Biol Phys. 1993 Jan 15; 25(2):193-207.
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Constine LS, Woolf PD, Cann D, Mick G, McCormick K, Raubertas RF, Rubin P. Hypothalamic-pituitary dysfunction after radiation for brain tumors. N Engl J Med. 1993 Jan 14; 328(2):87-94.
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Hays DM, Fryer CJ, Pringle KC, Collins RD, Hutchinson RJ, O'Neill JA, Constine LS, Heller RM, Davis PC, Nachman J, et al. An evaluation of abdominal staging procedures performed in pediatric patients with advanced Hodgkin's disease: a report from the Childrens Cancer Study Group. J Pediatr Surg. 1992 Sep; 27(9):1175-80.
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Karasek K, Constine LS, Rosier R. Sarcoma therapy: functional outcome and relationship to treatment parameters. Int J Radiat Oncol Biol Phys. 1992; 24(4):651-6.
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Constine LS, Donaldson SS. Pediatric radiation oncology--subspecialty training? Int J Radiat Oncol Biol Phys. 1992; 24(5):881-4.
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Kun LE, Constine LS. Medulloblastoma--caution regarding new treatment approaches. Int J Radiat Oncol Biol Phys. 1991 Apr; 20(4):897-9.
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Constine LS, Harwell S, Keng P, Lee F, Rubin P, Siemann D. Interleukin 1 alpha stimulates hemopoiesis but not tumor cell proliferation and protects mice from lethal total body irradiation. Int J Radiat Oncol Biol Phys. 1991 Mar; 20(3):447-56.
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Constine LS. Late effects of radiation therapy. Pediatrician. 1991; 18(1):37-48.
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Fryer CJ, Hutchinson RJ, Krailo M, Collins RD, Constine LS, Hays DM, Heller RM, Davis PC, Nachman J, O'Brien RT, et al. Efficacy and toxicity of 12 courses of ABVD chemotherapy followed by low-dose regional radiation in advanced Hodgkin's disease in children: a report from the Children's Cancer Study Group. J Clin Oncol. 1990 Dec; 8(12):1971-80.
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Savage DE, Constine LS, Schwartz RG, Rubin P. Radiation effects on left ventricular function and myocardial perfusion in long term survivors of Hodgkin's disease. Int J Radiat Oncol Biol Phys. 1990 Sep; 19(3):721-7.
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Bleyer WA, Fallavollita J, Robison L, Balsom W, Meadows A, Heyn R, Sitarz A, Ortega J, Miller D, Constine L, et al. Influence of age, sex, and concurrent intrathecal methotrexate therapy on intellectual function after cranial irradiation during childhood: a report from the Children's Cancer Study Group. Pediatr Hematol Oncol. 1990; 7(4):329-38.
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Constine LS, Randall SH, Rubin P, McDonald J. Craniopharyngiomas: fluctuation in cyst size following surgery and radiation therapy. Neurosurgery. 1989 Jan; 24(1):53-9.
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Rubin P, Whitaker JN, Ceckler TL, Nelson D, Gregory PK, Baggs RB, Constine LS, Herman PK. Myelin basic protein and magnetic resonance imaging for diagnosing radiation myelopathy. Int J Radiat Oncol Biol Phys. 1988 Dec; 15(6):1371-81.
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Constine LS, Konski A, Ekholm S, McDonald S, Rubin P. Adverse effects of brain irradiation correlated with MR and CT imaging. Int J Radiat Oncol Biol Phys. 1988 Aug; 15(2):319-30.
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Rubin P, Constine LS, Van Ess JD. Scoring of late toxic effects--interaction of two modalities. NCI Monogr. 1988; (6):9-18.
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Constine LS, Rubin P, Woolf PD, Doane K, Lush CM. Hyperprolactinemia and hypothyroidism following cytotoxic therapy for central nervous system malignancies. J Clin Oncol. 1987 Nov; 5(11):1841-51.
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Constine LS, Rubin P, Gregory P. The differential protection by WR2721 of skin versus growing cartilage following irradiation in weanling rats. Radiat Res. 1987 Apr; 110(1):61-71.
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Constine LS, Zagars G, Rubin P, Kligerman M. Protection by WR-2721 of human bone marrow function following irradiation. Int J Radiat Oncol Biol Phys. 1986 Aug; 12(8):1505-8.
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Rubin P, Constine L, Bennett JM. Hodgkin's disease. IIB or not to be--using irradiation alone or in combination with chemotherapy? That is the question! J Clin Oncol. 1986 Apr; 4(4):455-7.
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Frantz CN, Duerst RE, Ryan DH, Constine LS, Gelsomino N, Rust L, Gregory P. A monoclonal anti-neuroblastoma antibody that discriminates between human nonhematopoietic and hematopoietic cell types. Hybridoma. 1986; 5(4):297-306.
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Rubin P, Salazar O, Zagars G, Constine LS, Keys H, Poulter CA, Van Ess JD. Systemic hemibody irradiation for overt and occult metastases. Cancer. 1985 May 1; 55(9 Suppl):2210-21.
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Frantz CN, Duerst RE, Ryan DH, Gelsomino NL, Constine LS, Gregory PK. Anti-neuroblastoma monoclonal antibodies which do not bind to bone marrow cells. Prog Clin Biol Res. 1985; 175:485-99.
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Nakissa N, Constine LS, Rubin P, Strohl R. Birth defects in three common pediatric malignancies; Wilms' tumor, neuroblastoma and Ewing's sarcoma. Oncology. 1985; 42(6):358-63.
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Rubin P, Constine LS, Scarantino CW. The paradoxes in patterns and mechanism of bone marrow regeneration after irradiation. 2. Total body irradiation. Radiother Oncol. 1984 Oct; 2(3):227-33.
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Keng PC, Rubin P, Constine LS, Frantz C, Nakissa N, Gregory P. Characterization of the biophysical properties of human tumor and bone marrow cells as a preliminary step to the use of centrifugal elutriation in autologous bone marrow transplantation. Int J Radiat Oncol Biol Phys. 1984 Oct; 10(10):1913-22.
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Scarantino CW, Rubin P, Constine LS. The paradoxes in patterns and mechanism of bone marrow regeneration after irradiation. 1. Different volumes and doses. Radiother Oncol. 1984 Oct; 2(3):215-25.
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Constine LS, Donaldson SS, McDougall IR, Cox RS, Link MP, Kaplan HS. Thyroid dysfunction after radiotherapy in children with Hodgkin's disease. Cancer. 1984 Feb 15; 53(4):878-83.
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Coleman CN, Lee WW, Constine LS, Brown JM. The development of an oral prodrug, SR-2545, of the 2-nitroimidazole radiosensitizer SR-2508. Int J Radiat Oncol Biol Phys. 1982 Mar-Apr; 8(3-4):431-4.
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Constine LS, McDougall IR. Radiation therapy for Hodgkin's disease followed by hypothyroidism and then Graves' hyperthyroidism. Clin Nucl Med. 1982 Feb; 7(2):69-70.
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Rubin P, Van Houtte P, Constine L. Radiation sensitivity and organ tolerances in pediatric oncology: a new hypothesis. Front Radiat Ther Oncol. 1981; 16:62-82.
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Silverman S, Constine L, Harvey W, Grahame R. Survey of joint mobility and in vivo skin elasticity in London schoolchildren. Ann Rheum Dis. 1975 Apr; 34(2):177-80.
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Silverman S, Constine L, Harvey W, Grahame R. Proceedings: Survey of joint mobility and in vivo skin elasticity in London school children. Ann Rheum Dis. 1973 Nov; 32(6):588.
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