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Drag Anders

TitleProfessor Emeritus
InstitutionSchool of Medicine and Dentistry
DepartmentPharmacology and Physiology
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 711
Rochester NY 14642
Other Positions
TitleProfessor Emeritus
InstitutionSchool of Medicine and Dentistry
DepartmentAnesthesiology

TitleProfessor Emeritus
InstitutionSchool of Medicine and Dentistry
DepartmentEnvironmental Medicine

 
 Awards And Honors
1986 - 1996MERIT Awardee, National Institute of Environmental Health Sciences
1999     Bernard B. Brodie Award in Drug Metabolism, American Society for Pharmacology and Experimental Therapeutics
2002     Symposium on "Bioactivation of Foreign Compounds Challenges for the Future." Held in honor of Professor Drag Anders. Hosted by the Center for Molecular Toxicology, Vanderbilt University, Nashville, TN
2003     Merit Award, Society of Toxicology
 
 Selected Publications
List All   |   Timeline
  1. Anders MW. Exploiting endobiotic metabolic pathways to target xenobiotic antioxidants to mitochondria. Mitochondrion. 2013 Sep; 13(5):454-63.
    View in: PubMed
  2. Lange T, Ullrich S, Müller I, Nentwich MF, Stübke K, Feldhaus S, Knies C, Hellwinkel OJ, Vessella RL, Abramjuk C, Anders M, Schröder-Schwarz J, Schlomm T, Huland H, Sauter G, Schumacher U. Human prostate cancer in a clinically relevant xenograft mouse model: identification of ß(1,6)-branched oligosaccharides as a marker of tumor progression. Clin Cancer Res. 2012 Mar 1; 18(5):1364-73.
    View in: PubMed
  3. Board PG, Anders MW. Glutathione transferase zeta: discovery, polymorphic variants, catalysis, inactivation, and properties of Gstz1-/- mice. Drug Metab Rev. 2011 May; 43(2):215-25.
    View in: PubMed
  4. Anders MW. Putting bioactivation reactions to work: Targeting antioxidants to mitochondria. Chem Biol Interact. 2011 Jun 30; 192(1-2):8-13.
    View in: PubMed
  5. Anders MW, Andersen ME, Clewell HJ, Gargas ML, Guengerich FP, Reitz RH. Comment on M.V. Evans and J.C. Caldwell: evaluation of two different metabolic hypotheses for dichloromethane toxicity using physiologically based pharmacokinetic modeling of in vivo gas uptake data exposure in female B6C3F1 mice, Toxicol. Appl. Pharmacol., 244, 280-290, 2010. Toxicol Appl Pharmacol. 2010 Oct 1; 248(1):63-4; author reply 65-7.
    View in: PubMed
  6. Roser KS, Brookes PS, Wojtovich AP, Olson LP, Shojaie J, Parton RL, Anders MW. Mitochondrial biotransformation of omega-(phenoxy)alkanoic acids, 3-(phenoxy)acrylic acids, and omega-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: a prodrug strategy for targeting cytoprotective antioxidants to mitochondria. Bioorg Med Chem. 2010 Feb 15; 18(4):1441-8.
    View in: PubMed
  7. Board PG, Coggan M, Cappello J, Zhou H, Oakley AJ, Anders MW. S-(4-Nitrophenacyl)glutathione is a specific substrate for glutathione transferase omega 1-1. Anal Biochem. 2008 Mar 1; 374(1):25-30.
    View in: PubMed
  8. Anders MW. Chemical toxicology of reactive intermediates formed by the glutathione-dependent bioactivation of halogen-containing compounds. Chem Res Toxicol. 2008 Jan; 21(1):145-59.
    View in: PubMed
  9. Board PG, Anders MW. Glutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones. Chem Res Toxicol. 2007 Jan; 20(1):149-54.
    View in: PubMed
  10. Xu L, Krenitsky DM, Seacat AM, Butenhoff JL, Tephly TR, Anders MW. N-glucuronidation of perfluorooctanesulfonamide by human, rat, dog, and monkey liver microsomes and by expressed rat and human UDP-glucuronosyltransferases. Drug Metab Dispos. 2006 Aug; 34(8):1406-10.
    View in: PubMed
  11. Fang YY, Kashkarov U, Anders MW, Board PG. Polymorphisms in the human glutathione transferase zeta promoter. Pharmacogenet Genomics. 2006 May; 16(5):307-13.
    View in: PubMed
  12. Starr TB, Matanoski G, Anders MW, Andersen ME. Workshop overview: reassessment of the cancer risk of dichloromethane in humans. Toxicol Sci. 2006 May; 91(1):20-8.
    View in: PubMed
  13. Anders MW, Robotham JL, Sheu SS. Mitochondria: new drug targets for oxidative stress-induced diseases. Expert Opin Drug Metab Toxicol. 2006 Feb; 2(1):71-9.
    View in: PubMed
  14. Lacher MD, Tiirikainen MI, Saunier EF, Christian C, Anders M, Oft M, Balmain A, Akhurst RJ, Korn WM. Transforming growth factor-beta receptor inhibition enhances adenoviral infectability of carcinoma cells via up-regulation of Coxsackie and Adenovirus Receptor in conjunction with reversal of epithelial-mesenchymal transition. Cancer Res. 2006 Feb 1; 66(3):1648-57.
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  15. Sheu SS, Nauduri D, Anders MW. Targeting antioxidants to mitochondria: a new therapeutic direction. Biochim Biophys Acta. 2006 Feb; 1762(2):256-65.
    View in: PubMed
  16. Blackburn AC, Matthaei KI, Lim C, Taylor MC, Cappello JY, Hayes JD, Anders MW, Board PG. Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways. Mol Pharmacol. 2006 Feb; 69(2):650-7.
    View in: PubMed
  17. Anders MW. Formation and toxicity of anesthetic degradation products. Annu Rev Pharmacol Toxicol. 2005; 45:147-76.
    View in: PubMed
  18. Board PG, Anders MW. Human glutathione transferase zeta. Methods Enzymol. 2005; 401:61-77.
    View in: PubMed
  19. Anders MW. Glutathione-dependent bioactivation of haloalkanes and haloalkenes. Drug Metab Rev. 2004 Oct; 36(3-4):583-94.
    View in: PubMed
  20. Brookes PS, Yoon Y, Robotham JL, Anders MW, Sheu SS. Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am J Physiol Cell Physiol. 2004 Oct; 287(4):C817-33.
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  21. Lim CE, Matthaei KI, Blackburn AC, Davis RP, Dahlstrom JE, Koina ME, Anders MW, Board PG. Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class glutathione transferases. Am J Pathol. 2004 Aug; 165(2):679-93.
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  22. Xu L, Krenitsky DM, Seacat AM, Butenhoff JL, Anders MW. Biotransformation of N-ethyl-N-(2-hydroxyethyl)perfluorooctanesulfonamide by rat liver microsomes, cytosol, and slices and by expressed rat and human cytochromes P450. Chem Res Toxicol. 2004 Jun; 17(6):767-75.
    View in: PubMed
  23. Anderson WB, Board PG, Anders MW. Glutathione transferase zeta-catalyzed bioactivation of dichloroacetic acid: reaction of glyoxylate with amino acid nucleophiles. Chem Res Toxicol. 2004 May; 17(5):650-62.
    View in: PubMed
  24. Lantum HB, Iyer RA, Anders MW. Acivicin-induced alterations in renal and hepatic glutathione concentrations and in gamma-glutamyltransferase activities. Biochem Pharmacol. 2004 Apr 1; 67(7):1421-6.
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  25. Board PG, Taylor MC, Coggan M, Parker MW, Lantum HB, Anders MW. Clarification of the role of key active site residues of glutathione transferase zeta/maleylacetoacetate isomerase by a new spectrophotometric technique. Biochem J. 2003 Sep 15; 374(Pt 3):731-7.
    View in: PubMed
  26. Lantum HB, Cornejo J, Pierce RH, Anders MW. Perturbation of maleylacetoacetic acid metabolism in rats with dichloroacetic Acid-induced glutathione transferase zeta deficiency. Toxicol Sci. 2003 Jul; 74(1):192-202.
    View in: PubMed
  27. Anders M, Christian C, McMahon M, McCormick F, Korn WM. Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells. Cancer Res. 2003 May 1; 63(9):2088-95.
    View in: PubMed
  28. Jolivette LJ, Anders MW. Computational and experimental studies on the distribution of addition and substitution products of the microsomal glutathione transferase 1-catalyzed conjugation of glutathione with fluoroalkenes. Chem Res Toxicol. 2003 Feb; 16(2):137-44.
    View in: PubMed
  29. Lantum HB, Baggs RB, Krenitsky DM, Anders MW. Nephrotoxicity of chlorofluoroacetic acid in rats. Toxicol Sci. 2002 Dec; 70(2):261-8.
    View in: PubMed
  30. Anderson WB, Liebler DC, Board PG, Anders MW. Mass spectral characterization of dichloroacetic acid-modified human glutathione transferase zeta. Chem Res Toxicol. 2002 Nov; 15(11):1387-97.
    View in: PubMed
  31. Cooper AJ, Bruschi SA, Anders MW. Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism. Biochem Pharmacol. 2002 Aug 15; 64(4):553-64.
    View in: PubMed
  32. Jolivette LJ, Anders MW. Structure-activity relationship for the biotransformation of haloalkenes by rat liver microsomal glutathione transferase 1. Chem Res Toxicol. 2002 Aug; 15(8):1036-41.
    View in: PubMed
  33. Lantum HB, Board PG, Anders MW. Kinetics of the biotransformation of maleylacetone and chlorofluoroacetic acid by polymorphic variants of human glutathione transferase zeta (hGSTZ1-1). Chem Res Toxicol. 2002 Jul; 15(7):957-63.
    View in: PubMed
  34. Enomoto A, Wempe MF, Tsuchida H, Shin HJ, Cha SH, Anzai N, Goto A, Sakamoto A, Niwa T, Kanai Y, Anders MW, Endou H. Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition. J Biol Chem. 2002 Sep 27; 277(39):36262-71.
    View in: PubMed
  35. Lantum HB, Baggs RB, Krenitsky DM, Board PG, Anders MW. Immunohistochemical localization and activity of glutathione transferase zeta (GSTZ1-1) in rat tissues. Drug Metab Dispos. 2002 Jun; 30(6):616-25.
    View in: PubMed
  36. Bayer T, Amberg A, Bertermann R, Rusch GM, Anders MW, Dekant W. Biotransformation of 1,1,1,3,3-Pentafluoropropane (HFC-245fa). Chem Res Toxicol. 2002 May; 15(5):723-33.
    View in: PubMed
  37. Tong Z, Anders MW. Reactive intermediate formation from the 2-(Fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A)-derived cysteine S-conjugate S-[2-(Fluoromethoxy)-1,1,3,3,3-pentafluoropropyl]-L-cysteine in pyridoxal model systems. Chem Res Toxicol. 2002 May; 15(5):623-8.
    View in: PubMed
  38. Lantum HB, Liebler DC, Board PG, Anders MW. Alkylation and inactivation of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone. Chem Res Toxicol. 2002 May; 15(5):707-16.
    View in: PubMed
  39. Uchino H, Kanai Y, Kim DK, Wempe MF, Chairoungdua A, Morimoto E, Anders MW, Endou H. Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition. Mol Pharmacol. 2002 Apr; 61(4):729-37.
    View in: PubMed
  40. Blackburn AC, Coggan M, Tzeng HF, Lantum H, Polekhina G, Parker MW, Anders MW, Board PG. GSTZ1d: a new allele of glutathione transferase zeta and maleylacetoacetate isomerase. Pharmacogenetics. 2001 Nov; 11(8):671-8.
    View in: PubMed
  41. Pombrio JM, Giangreco A, Li L, Wempe MF, Anders MW, Sweet DH, Pritchard JB, Ballatori N. Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1. Mol Pharmacol. 2001 Nov; 60(5):1091-9.
    View in: PubMed
  42. DeCory HH, Piech-Dumas KM, Sheu SS, Federoff HJ, Anders MW. Efflux of glutathione conjugate of monochlorobimane from striatal and cortical neurons. Drug Metab Dispos. 2001 Oct; 29(10):1256-62.
    View in: PubMed
  43. Board PG, Chelvanayagam G, Jermiin LS, Tetlow N, Tzeng HF, Anders MW, Blackburn AC. Identification of novel glutathione transferases and polymorphic variants by expressed sequence tag database analysis. Drug Metab Dispos. 2001 Apr; 29(4 Pt 2):544-7.
    View in: PubMed
  44. Chen Y, Cai J, Anders MW, Stevens JL, Jones DP. Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis. Toxicol Appl Pharmacol. 2001 Feb 1; 170(3):172-80.
    View in: PubMed
  45. Lantum HB, Board PG, Anders MW. Inactivation of polymorphic variants of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone. Adv Exp Med Biol. 2001; 500:339-42.
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  46. Anders MW. Formation and fate of reactive intermediates of haloalkanes, haloalkenes, and alpha-haloacids. Adv Exp Med Biol. 2001; 500:113-20.
    View in: PubMed
  47. Luu NC, Iyer RA, Anders MW, Ridge DP. Bioactivation mechanisms of haloalkene cysteine S-conjugates modeled by gas-phase, ion-molecule reactions. Chem Res Toxicol. 2000 Jul; 13(7):610-5.
    View in: PubMed
  48. Uttamsingh V, Baggs RB, Krenitsky DM, Anders MW. Immunohistochemical localization of the acylases that catalyze the deacetylation of N-acetyl-L-cysteine and haloalkene-derived mercapturates. Drug Metab Dispos. 2000 Jun; 28(6):625-32.
    View in: PubMed
  49. Tzeng HF, Blackburn AC, Board PG, Anders MW. Polymorphism- and species-dependent inactivation of glutathione transferase zeta by dichloroacetate. Chem Res Toxicol. 2000 Apr; 13(4):231-6.
    View in: PubMed
  50. Kraus T, Uttamsingh V, Anders MW, Wolf S. Porcine kidney microsomal cysteine S-conjugate N-acetyltransferase-catalyzed N-acetylation of haloalkene-derived cysteine S-conjugates. Drug Metab Dispos. 2000 Apr; 28(4):440-5.
    View in: PubMed
  51. Blackburn AC, Tzeng HF, Anders MW, Board PG. Discovery of a functional polymorphism in human glutathione transferase zeta by expressed sequence tag database analysis. Pharmacogenetics. 2000 Feb; 10(1):49-57.
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  52. Morrow PE, Witschi H, Vore M, Hakkinen PE, MacGregor J, MacGregor J, Anders MW, Willhite C. Profiles in toxicology. Harold Carpenter Hodge (1904-1990). Toxicol Sci. 2000 Feb; 53(2):157-8.
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  53. Anderson WB, Board PG, Gargano B, Anders MW. Inactivation of glutathione transferase zeta by dichloroacetic acid and other fluorine-lacking alpha-haloalkanoic acids. Chem Res Toxicol. 1999 Dec; 12(12):1144-9.
    View in: PubMed
  54. Uttamsingh V, Anders MW. Acylase-catalyzed deacetylation of haloalkene-derived mercapturates. Chem Res Toxicol. 1999 Oct; 12(10):937-42.
    View in: PubMed
  55. Wempe MF, Anderson WB, Tzeng HF, Board PG, Anders MW. Glutathione transferase zeta-catalyzed biotransformation of deuterated dihaloacetic acids. Biochem Biophys Res Commun. 1999 Aug 11; 261(3):779-83.
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  56. Tu Z, Anders MW. Identification of an important cysteine residue in human glutamate-cysteine ligase catalytic subunit by site-directed mutagenesis. Biochem J. 1998 Dec 15; 336 ( Pt 3):675-80.
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  57. Tong Z, Board PG, Anders MW. Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other alpha-haloacids. Chem Res Toxicol. 1998 Nov; 11(11):1332-8.
    View in: PubMed
  58. Uttamsingh V, Iyer RA, Baggs RB, Anders MW. Fate and toxicity of 2-(fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A)-derived mercapturates in male, Fischer 344 rats. Anesthesiology. 1998 Nov; 89(5):1174-83.
    View in: PubMed
  59. Tong Z, Utell MJ, Morrow PE, Rusch GM, Anders MW. Metabolism of 1,1-dichloro-1-fluoroethane (HCFC-141b) in human volunteers. Drug Metab Dispos. 1998 Jul; 26(7):711-3.
    View in: PubMed
  60. Uttamsingh V, Keller DA, Anders MW. Acylase I-catalyzed deacetylation of N-acetyl-L-cysteine and S-alkyl-N-acetyl-L-cysteines. Chem Res Toxicol. 1998 Jul; 11(7):800-9.
    View in: PubMed
  61. Jolivette LJ, Kende AS, Anders MW. Thietanium ion formation from the food mutagen 2-chloro-4-(methylthio)butanoic acid. Chem Res Toxicol. 1998 Jul; 11(7):794-9.
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  62. Tu Z, Anders MW. Expression and characterization of human glutamate-cysteine ligase. Arch Biochem Biophys. 1998 Jun 15; 354(2):247-54.
    View in: PubMed
  63. Tong Z, Board PG, Anders MW. Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid. Biochem J. 1998 Apr 15; 331 ( Pt 2):371-4.
    View in: PubMed
  64. Tu Z, Anders MW. Up-regulation of glutamate-cysteine ligase gene expression by butylated hydroxytoluene is mediated by transcription factor AP-1. Biochem Biophys Res Commun. 1998 Mar 27; 244(3):801-5.
    View in: PubMed
  65. Iyer RA, Frink EJ, Ebert TJ, Anders MW. Cysteine conjugate beta-lyase-dependent metabolism of compound A (2-[fluoromethoxy]-1,1,3,3,3-pentafluoro-1-propene) in human subjects anesthetized with sevoflurane and in rats given compound A. Anesthesiology. 1998 Mar; 88(3):611-8.
    View in: PubMed
  66. Baker-Malcolm JF, Haeffner-Gormley L, Wang L, Anders MW, Thorpe C. Elimination reactions in the medium-chain acyl-CoA dehydrogenase: bioactivation of cytotoxic 4-thiaalkanoic acids. Biochemistry. 1998 Feb 3; 37(5):1383-93.
    View in: PubMed
  67. Anders MW, Dekant W. Glutathione-dependent bioactivation of haloalkenes. Annu Rev Pharmacol Toxicol. 1998; 38:501-37.
    View in: PubMed
  68. Iyer RA, Baggs RB, Anders MW. Nephrotoxicity of the glutathione and cysteine S-conjugates of the sevoflurane degradation product 2-(fluoromethoxy)-1,1,3,3, 3-pentafluoro-1-propene (Compound A) in male Fischer 344 rats. J Pharmacol Exp Ther. 1997 Dec; 283(3):1544-51.
    View in: PubMed
  69. Anders MW, Dekant W. Liver abnormalities and hydrochlorofluorocarbons. Lancet. 1997 Oct 25; 350(9086):1249; author reply 1249-50.
    View in: PubMed
  70. Tu Z, Anders MW. Enhancement of gene expression by transcription factor AP-1 is dependent on orientation of AP-1 element. Biochem Biophys Res Commun. 1997 Sep 18; 238(2):285-8.
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  71. Otieno MA, Anders MW. Cysteine S-conjugates activate transcription factor NF-kappa B in cultured renal epithelial cells. Am J Physiol. 1997 Jul; 273(1 Pt 2):F136-43.
    View in: PubMed
  72. Iyer RA, Anders MW. Cysteine conjugate beta-lyase-dependent biotransformation of the cysteine S-conjugates of the sevoflurane degradation product 2-(fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A). Chem Res Toxicol. 1997 Jul; 10(7):811-9.
    View in: PubMed
  73. Otieno MA, Anders MW. Stable transfection of LLC-PK1 cells with human microsomal glutathione S-transferase gene increases haloalkene glutathione S-conjugate formation and cytotoxicity. Biochem Biophys Res Commun. 1997 May 19; 234(2):481-4.
    View in: PubMed
  74. Otieno MA, Baggs RB, Hayes JD, Anders MW. Immunolocalization of microsomal glutathione S-transferase in rat tissues. Drug Metab Dispos. 1997 Jan; 25(1):12-20.
    View in: PubMed
  75. Loizou GD, Tran CL, Anders MW. Physiologically based pharmacokinetic analysis of the concentration-dependent metabolism of halothane. Xenobiotica. 1997 Jan; 27(1):87-99.
    View in: PubMed
  76. Iyer RA, Anders MW. Cysteine conjugate beta-lyase-dependent biotransformation of the cysteine S-conjugates of the sevoflurane degradation product compound A in human, nonhuman primate, and rat kidney cytosol and mitochondria. Anesthesiology. 1996 Dec; 85(6):1454-61.
    View in: PubMed
  77. Hashmi M, Gräf S, Braun M, Anders MW. Enantioselective depletion of mitochondrial glutathione concentrations by (S)- and (R)-3-hydroxy-4-pentenoate. Chem Res Toxicol. 1996 Mar; 9(2):361-4.
    View in: PubMed
  78. Shimoji M, Aniya Y, Anders MW. Preferential proteolysis and activation of oxidatively modified liver microsomal glutathione S-transferase of rat. Biol Pharm Bull. 1996 Feb; 19(2):209-13.
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  79. Lock EA, Sani Y, Moore RB, Finkelstein MB, Anders MW, Seawright AA. Bone marrow and renal injury associated with haloalkene cysteine conjugates in calves. Arch Toxicol. 1996; 70(10):607-19.
    View in: PubMed
  80. Yin H, Crowder RJ, Jones JP, Anders MW. Reaction of trifluoroacetaldehyde with amino acids, nucleotides, lipid nucleophiles, and their analogs. Chem Res Toxicol. 1996 Jan-Feb; 9(1):140-6.
    View in: PubMed
  81. Finkelstein MB, Dekant W, Anders MW. Cysteine conjugate beta-lyase-catalyzed bioactivation of bromine-containing cysteine S-conjugates: stoichiometry and formation of 2,2-difluoro-3-halothiiranes. Chem Res Toxicol. 1996 Jan-Feb; 9(1):227-31.
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  82. Anders MW, Yin H, Jones JP. Application of computational chemistry in the study of biologically reactive intermediates. Adv Exp Med Biol. 1996; 387:347-53.
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  83. Yin H, Anders MW, Jones JP. Metabolism of 1,2-dichloro-1-fluoroethane and 1-fluoro-1,2,2-trichloroethane: electronic factors govern the regioselectivity of cytochrome P450-dependent oxidation. Chem Res Toxicol. 1996 Jan-Feb; 9(1):50-7.
    View in: PubMed
  84. Yin H, Anders MW, Korzekwa KR, Higgins L, Thummel KE, Kharasch ED, Jones JP. Designing safer chemicals: predicting the rates of metabolism of halogenated alkanes. Proc Natl Acad Sci U S A. 1995 Nov 21; 92(24):11076-80.
    View in: PubMed
  85. Zhang TL, Wang L, Hashmi M, Anders MW, Thorpe C, Ridge DP. Fourier-transform ion cyclotron resonance mass spectrometric evidence for the formation of alpha-chloroenethiolates and thioketenes from chloroalkene-derived, cytotoxic 4-thiaalkanoates. Chem Res Toxicol. 1995 Oct-Nov; 8(7):907-10.
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  86. Loizou GD, Anders MW. Gas-uptake pharmacokinetics and metabolism of 2-chloro-1,1,1,2-tetrafluoroethane (HCFC-124) in the rat, mouse, and hamster. Drug Metab Dispos. 1995 Aug; 23(8):875-80.
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  87. Anders MW. Mitochondrial bioactivation of cysteine S-conjugates and 4-thiaalkanoates: implications for mitochondrial dysfunction and mitochondrial diseases. Biochim Biophys Acta. 1995 May 24; 1271(1):51-7.
    View in: PubMed
  88. Fitzsimmons ME, Thorpe C, Anders MW. Medium-chain acyl-CoA dehydrogenase- and enoyl-CoA hydratase-dependent bioactivation of 5,6-dichloro-4-thia-5-hexenoyl-CoA. Biochemistry. 1995 Apr 4; 34(13):4276-86.
    View in: PubMed
  89. Yin H, Jones JP, Anders MW. Metabolism of 1-fluoro-1,1,2-trichloroethane, 1,2-dichloro-1,1-difluoroethane, and 1,1,1-trifluoro-2-chloroethane. Chem Res Toxicol. 1995 Mar; 8(2):262-8.
    View in: PubMed
  90. Finkelstein MB, Patel NJ, Anders MW. Metabolism of [14C]- and [35S]S-(1,2-dichlorovinyl)-L-cysteine in the male Fischer 344 rat. Drug Metab Dispos. 1995 Jan; 23(1):124-8.
    View in: PubMed
  91. Tanaka E, Anders MW. Biosynthesis of S-(2-chloro-1,1,2-trifluoroethyl)glutathione in rat and human hepatocytes and in Hep G2 cells. Drug Metab Dispos. 1995 Jan; 23(1):48-54.
    View in: PubMed
  92. Heyn H, Bankmann YG, Anders MW. Tissue distribution and stereoselectivity of remacemide-glycine hydrolase. Drug Metab Dispos. 1994 Nov-Dec; 22(6):973-4.
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  93. Birner G, Richling C, Henschler D, Anders MW, Dekant W. Metabolism of tetrachloroethene in rats: identification of N epsilon-(dichloroacetyl)-L-lysine and N epsilon-(trichloroacetyl)-L-lysine as protein adducts. Chem Res Toxicol. 1994 Nov-Dec; 7(6):724-32.
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  94. Fitzsimmons ME, Baggs RB, Anders MW. Nephrotoxicity and hepatotoxicity of 5,6-dichloro-4-thia-5-hexenoic acid: evidence for fatty acid beta-oxidation-dependent bioactivation. J Pharmacol Exp Ther. 1994 Oct; 271(1):515-23.
    View in: PubMed
  95. Loizou GD, Urban G, Dekant W, Anders MW. Gas-uptake pharmacokinetics of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123). Drug Metab Dispos. 1994 Jul-Aug; 22(4):511-7.
    View in: PubMed
  96. Heyn H, McCarthy DJ, Curry SH, Eisman MS, Anders MW. Brain uptake and biotransformation of remacemide hydrochloride, a novel anticonvulsant. Drug Metab Dispos. 1994 May-Jun; 22(3):443-6.
    View in: PubMed
  97. Hashmi M, Dechert S, Dekant W, Anders MW. Bioactivation of [13C]dichloromethane in mouse, rat, and human liver cytosol: 13C nuclear magnetic resonance spectroscopic studies. Chem Res Toxicol. 1994 May-Jun; 7(3):291-6.
    View in: PubMed
  98. Finkelstein MB, Vamvakas S, Bittner D, Anders MW. Structure-mutagenicity and structure-cytotoxicity studies on bromine-containing cysteine S-conjugates and related compounds. Chem Res Toxicol. 1994 Mar-Apr; 7(2):157-63.
    View in: PubMed
  99. Dekant W, Vamvakas S, Anders MW. Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: cysteine conjugate beta-lyase pathway. Adv Pharmacol. 1994; 27:115-62.
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  100. Anders MW, Dekant W. Aminoacylases. Adv Pharmacol. 1994; 27:431-48.
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  101. Patel N, Birner G, Dekant W, Anders MW. Glutathione-dependent biosynthesis and bioactivation of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine, the glutathione and cysteine S-conjugates of dichloroacetylene, in rat tissues and subcellular fractions. Drug Metab Dispos. 1994 Jan-Feb; 22(1):143-7.
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  102. Vamvakas S, Anders MW. Bioconversion of prodrugs by conjugate-processing enzymes. Adv Pharmacol. 1994; 27:479-99.
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  103. Fitzsimmons ME, Anders MW. Fatty acid beta-oxidation-dependent bioactivation of halogenated thiaalkanoic acids in isolated rat hepatocytes. Chem Res Toxicol. 1993 Sep-Oct; 6(5):662-8.
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  104. Yin H, Jones JP, Anders MW. Slow-binding inhibition of carboxylesterase and other serine hydrolases by chlorodifluoroacetaldehyde. Chem Res Toxicol. 1993 Sep-Oct; 6(5):630-4.
    View in: PubMed
  105. Loizou GD, Anders MW. Gas-uptake pharmacokinetics and biotransformation of 1,1-dichloro-1-fluoroethane (HCFC-141b). Drug Metab Dispos. 1993 Jul-Aug; 21(4):634-9.
    View in: PubMed
  106. Patel NJ, Fullone JS, Anders MW. Brain uptake of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine, the glutathione and cysteine S-conjugates of the neurotoxin dichloroacetylene. Brain Res Mol Brain Res. 1993 Jan; 17(1-2):53-8.
    View in: PubMed
  107. Shan X, Jones DP, Hashmi M, Anders MW. Selective depletion of mitochondrial glutathione concentrations by (R,S)-3-hydroxy-4-pentenoate potentiates oxidative cell death. Chem Res Toxicol. 1993 Jan-Feb; 6(1):75-81.
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  108. Vamvakas S, Bittner D, Dekant W, Anders MW. Events that precede and that follow S-(1,2-dichlorovinyl)-L-cysteine-induced release of mitochondrial Ca2+ and their association with cytotoxicity to renal cells. Biochem Pharmacol. 1992 Sep 25; 44(6):1131-8.
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  109. Anders MW, Dekant W, Vamvakas S. Glutathione-dependent toxicity. Xenobiotica. 1992 Sep-Oct; 22(9-10):1135-45.
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  110. Harris JW, Jones JP, Martin JL, LaRosa AC, Olson MJ, Pohl LR, Anders MW. Pentahaloethane-based chlorofluorocarbon substitutes and halothane: correlation of in vivo hepatic protein trifluoroacetylation and urinary trifluoroacetic acid excretion with calculated enthalpies of activation. Chem Res Toxicol. 1992 Sep-Oct; 5(5):720-5.
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  111. Simmons TW, Anders MW, Ballatori N. L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine transport in rat liver canalicular membrane vesicles: potential reabsorption mechanisms for biliary metabolites of glutathione and its S-conjugates. J Pharmacol Exp Ther. 1992 Sep; 262(3):1182-8.
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  112. Harris JW, Fitzsimmons ME, Anders MW. Synthesis of [2-3H-ethyl]S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine and its use in covalent-binding studies. Anal Biochem. 1992 Aug 1; 204(2):300-4.
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  113. Aniya Y, Anders MW. Activation of rat liver microsomal glutathione S-transferase by hydrogen peroxide: role for protein-dimer formation. Arch Biochem Biophys. 1992 Aug 1; 296(2):611-6.
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  114. Finkelstein MB, Baggs RB, Anders MW. Nephrotoxicity of the glutathione and cysteine conjugates of 2-bromo-2-chloro-1,1-difluoroethene. J Pharmacol Exp Ther. 1992 Jun; 261(3):1248-52.
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  115. Hashmi M, Vamvakas S, Anders MW. Bioactivation mechanism of S-(3-oxopropyl)-N-acetyl-L-cysteine, the mercapturic acid of acrolein. Chem Res Toxicol. 1992 May-Jun; 5(3):360-5.
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  116. Park SB, Osterloh JD, Vamvakas S, Hashmi M, Anders MW, Cashman JR. Flavin-containing monooxygenase-dependent stereoselective S-oxygenation and cytotoxicity of cysteine S-conjugates and mercapturates. Chem Res Toxicol. 1992 Mar-Apr; 5(2):193-201.
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  117. Olson JA, Moon RC, Anders MW, Fenselau C, Shane B. Enhancement of biological activity by conjugation reactions. J Nutr. 1992 Mar; 122(3 Suppl):615-24.
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  118. Harris JW, Dekant W, Anders MW. In vivo detection and characterization of protein adducts resulting from bioactivation of haloethene cysteine S-conjugates by 19F NMR: chlorotrifluoroethene and tetrafluoroethene. Chem Res Toxicol. 1992 Jan-Feb; 5(1):34-41.
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  119. Anders MW. Metabolism and toxicity of hydrochlorofluorocarbons: current knowledge and needs for the future. Environ Health Perspect. 1991 Dec; 96:185-91.
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  120. Hargus SJ, Anders MW. Immunochemical detection of covalently modified kidney proteins in S-(1,1,2,2-tetrafluoroethyl)-L-cysteine-treated rats. Biochem Pharmacol. 1991 Oct 24; 42(10):R17-20.
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  121. Hashmi M, Anders MW. Enzymatic reaction of beta-N-methylaminoalanine with L-amino acid oxidase. Biochim Biophys Acta. 1991 May 24; 1074(1):36-9.
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  122. Gietl Y, Vamvakas S, Anders MW. Intestinal absorption of S-(pentachlorobutadienyl)glutathione and S-(pentachlorobutadienyl)-L-cysteine, the glutathione and cysteine S-conjugates of hexachlorobuta-1,3-diene. Drug Metab Dispos. 1991 May-Jun; 19(3):703-7.
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  123. Harris JW, Anders MW. In vivo metabolism of the hydrochlorofluorocarbon 1,1-dichloro-1-fluoroethane (HCFC-141b). Biochem Pharmacol. 1991 May 1; 41(9):R13-6.
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  124. Harris JW, Anders MW. Metabolism of the hydrochlorofluorocarbon 1,2-dichloro-1,1-difluoroethane. Chem Res Toxicol. 1991 Mar-Apr; 4(2):180-6.
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  125. Harris JW, Pohl LR, Martin JL, Anders MW. Tissue acylation by the chlorofluorocarbon substitute 2,2-dichloro-1,1,1-trifluoroethane. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1407-10.
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  126. Hargus SJ, Fitzsimmons ME, Aniya Y, Anders MW. Stereochemistry of the microsomal glutathione S-transferase catalyzed addition of glutathione to chlorotrifluoroethene. Biochemistry. 1991 Jan 22; 30(3):717-21.
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  127. Fitzsimmons ME, Anders MW. Fatty acid beta-oxidation-dependent bioactivation of 5,6-dichloro-4-thia-5-hexenoate and analogs in isolated rat hepatocytes. Adv Exp Med Biol. 1991; 283:281-4.
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  128. Hargus SJ, Fitzsimmons ME, Anders MW. Stereochemistry of the microsomal glutathione S-transferase-catalyzed addition of glutathione to chlorotrifluoroethene in isolated rat hepatocytes. Adv Exp Med Biol. 1991; 283:289-93.
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  129. Harris JW, Anders MW. The use of 19F NMR in the study of protein alkylation by fluorinated reactive intermediates. Adv Exp Med Biol. 1991; 283:735-8.
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  130. Vamvakas S, Anders MW. Formation of reactive intermediates by phase II enzymes: glutathione-dependent bioactivation reactions. Adv Exp Med Biol. 1991; 283:13-24.
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  131. Gietl YS, Anders MW. Biosynthesis and biliary excretion of S-conjugates of hexachlorobuta-1,3-diene in the perfused rat liver. Drug Metab Dispos. 1991 Jan-Feb; 19(1):274-7.
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  132. Monks TJ, Anders MW, Dekant W, Stevens JL, Lau SS, van Bladeren PJ. Glutathione conjugate mediated toxicities. Toxicol Appl Pharmacol. 1990 Oct; 106(1):1-19.
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  133. Vamvakas S, Sharma VK, Sheu SS, Anders MW. Perturbations of intracellular calcium distribution in kidney cells by nephrotoxic haloalkenyl cysteine S-conjugates. Mol Pharmacol. 1990 Oct; 38(4):455-61.
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  134. Vamvakas S, Anders MW. Perturbation of calcium homeostasis as a link between acute cell injury and carcinogenesis in the kidney. Toxicol Lett. 1990 Sep; 53(1-2):115-20.
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  135. Dekant W, Vamvakas S, Anders MW. Biosynthesis, bioactivation, and mutagenicity of S-conjugates. Toxicol Lett. 1990 Sep; 53(1-2):53-8.
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  136. Dekant W, Vamvakas S, Anders MW. Bioactivation of hexachlorobutadiene by glutathione conjugation. Food Chem Toxicol. 1990 Apr; 28(4):285-93.
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  137. Lash LH, Elfarra AA, Rakiewicz-Nemeth D, Anders MW. Bioactivation mechanism of cytotoxic homocysteine S-conjugates. Arch Biochem Biophys. 1990 Feb 1; 276(2):322-30.
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  138. Cooper AJ, Anders MW. Glutamine transaminase K and cysteine conjugate beta-lyase. Ann N Y Acad Sci. 1990; 585:118-27.
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  139. Anders MW. Glutathione-dependent bioactivation of xenobiotics: implications for mutagenicity and carcinogenicity. Princess Takamatsu Symp. 1990; 21:89-99.
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  140. Lash LH, Nelson RM, Van Dyke RA, Anders MW. Purification and characterization of human kidney cytosolic cysteine conjugate beta-lyase activity. Drug Metab Dispos. 1990 Jan-Feb; 18(1):50-4.
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  141. Cooper AJ, Hollander MM, Anders MW. Formation of highly reactive vinylglyoxylate (2-oxo-3-butenoate) from amino acids with good leaving groups in the gamma-position. Toxicological implications and therapeutic potential. Biochem Pharmacol. 1989 Nov 15; 38(22):3895-901.
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  142. Webster KD, Anders MW. Bioactivation mechanism of L-thiomorpholine-3-carboxylic acid. Arch Biochem Biophys. 1989 Sep; 273(2):562-71.
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  143. Aniya Y, Anders MW. Regulation of rat liver microsomal glutathione S-transferase activity by thiol/disulfide exchange. Arch Biochem Biophys. 1989 Apr; 270(1):330-4.
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  144. Banki K, Anders MW. Inhibition of rat kidney mitochondrial DNA, RNA and protein synthesis by halogenated cysteine S-conjugates. Carcinogenesis. 1989 Apr; 10(4):767-72.
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  145. Vamvakas S, Dekant W, Anders MW. Mutagenicity of benzyl S-haloalkyl and S-haloalkenyl sulfides in the Ames-test. Biochem Pharmacol. 1989 Mar 15; 38(6):935-9.
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  146. Aniya Y, Anders MW. Activation of rat liver microsomal glutathione S-transferase by reduced oxygen species. J Biol Chem. 1989 Feb 5; 264(4):1998-2002.
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  147. Lash LH, Anders MW. Uptake of nephrotoxic S-conjugates by isolated rat renal proximal tubular cells. J Pharmacol Exp Ther. 1989 Feb; 248(2):531-7.
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  148. Dekant W, Vamvakas S, Anders MW. Bioactivation of nephrotoxic haloalkenes by glutathione conjugation: formation of toxic and mutagenic intermediates by cysteine conjugate beta-lyase. Drug Metab Rev. 1989; 20(1):43-83.
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  149. Dekant W, Vamvakas S, Henschler D, Anders MW. Enzymatic conjugation of hexachloro-1,3-butadiene with glutathione. Formation of 1-(glutathion-S-yl)-1,2,3,4,4-pentachlorobuta-1,3-diene and 1,4-bis(glutathion-S-yl)-1,2,3,4-tetrachlorobuta-1,3-diene. Drug Metab Dispos. 1988 Sep-Oct; 16(5):701-6.
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  150. Vamvakas S, Elfarra AA, Dekant W, Henschler D, Anders MW. Mutagenicity of amino acid and glutathione S-conjugates in the Ames test. Mutat Res. 1988 Sep; 206(1):83-90.
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  151. Dekant W, Berthold K, Vamvakas S, Henschler D, Anders MW. Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2,2-trichlorovinyl)-L-cysteine formed by cysteine conjugate beta-lyase. Chem Res Toxicol. 1988 May-Jun; 1(3):175-8.
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  152. Aniya Y, McLenithan JC, Anders MW. Isozyme selective arylation of cytosolic glutathione S-transferase by [14C]bromobenzene metabolites. Biochem Pharmacol. 1988 Jan 15; 37(2):251-7.
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  153. Veltman JC, Dekant W, Guengerich FP, Anders MW. Cytotoxicity and bioactivation mechanism of benzyl 2-chloro-1,1,2-trifluoroethyl sulfide and benzyl 1,2,3,4,4-pentachlorobuta-1,3-dienyl sulfide. Chem Res Toxicol. 1988 Jan-Feb; 1(1):35-40.
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  154. Anders MW, Lash L, Dekant W, Elfarra AA, Dohn DR. Biosynthesis and biotransformation of glutathione S-conjugates to toxic metabolites. Crit Rev Toxicol. 1988; 18(4):311-41.
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  155. Dekant W, Lash LH, Anders MW. Bioactivation mechanism of the cytotoxic and nephrotoxic S-conjugate S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine. Proc Natl Acad Sci U S A. 1987 Nov; 84(21):7443-7.
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  156. Veltman JC, Anders MW. Cytotoxicity of N,N-bis(2-chloroethyl)-N-nitrosourea in hypoxic rat hepatocytes. Cancer Res. 1987 Oct 1; 47(19):5087-91.
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  157. Lash LH, Anders MW. Mechanism of S-(1,2-dichlorovinyl)-L-cysteine- and S-(1,2-dichlorovinyl)-L-homocysteine-induced renal mitochondrial toxicity. Mol Pharmacol. 1987 Oct; 32(4):549-56.
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  158. Webb WW, Elfarra AA, Webster KD, Thom RE, Anders MW. Role for an episulfonium ion in S-(2-chloroethyl)-DL-cysteine-induced cytotoxicity and its reaction with glutathione. Biochemistry. 1987 Jun 2; 26(11):3017-23.
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  159. Elfarra AA, Lash LH, Anders MW. Alpha-ketoacids stimulate rat renal cysteine conjugate beta-lyase activity and potentiate the cytotoxicity of S-(1,2-dichlorovinyl)-L-cysteine. Mol Pharmacol. 1987 Feb; 31(2):208-12.
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  160. Anders MW, Elfarra AA, Lash LH. Cellular effects of reactive intermediates: nephrotoxicity of S-conjugates of amino acids. Arch Toxicol. 1987; 60(1-3):103-8.
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  161. Lash LH, Elfarra AA, Anders MW. S-(1,2-dichlorovinyl)-L-homocysteine-induced cytotoxicity in isolated rat kidney cells. Arch Biochem Biophys. 1986 Dec; 251(2):432-9.
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  162. Lash LH, Anders MW. Cytotoxicity of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine in isolated rat kidney cells. J Biol Chem. 1986 Oct 5; 261(28):13076-81.
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  163. Banki K, Elfarra AA, Lash LH, Anders MW. Metabolism of S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine to hydrogen sulfide and the role of hydrogen sulfide in S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine-induced mitochondrial toxicity. Biochem Biophys Res Commun. 1986 Jul 31; 138(2):707-13.
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  164. Kelner MJ, McLenithan JC, Anders MW. Thiol stimulation of the cytochrome P-450-dependent reduction of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) to 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD). Biochem Pharmacol. 1986 Jun 1; 35(11):1805-7.
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  165. Lash LH, Elfarra AA, Anders MW. Renal cysteine conjugate beta-lyase. Bioactivation of nephrotoxic cysteine S-conjugates in mitochondrial outer membrane. J Biol Chem. 1986 May 5; 261(13):5930-5.
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  166. Elfarra AA, Lash LH, Anders MW. Metabolic activation and detoxication of nephrotoxic cysteine and homocysteine S-conjugates. Proc Natl Acad Sci U S A. 1986 Apr; 83(8):2667-71.
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  167. Elfarra AA, Jakobson I, Anders MW. Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity. Biochem Pharmacol. 1986 Jan 15; 35(2):283-8.
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  168. Anders MW, Lash LH, Elfarra AA. Nephrotoxic amino acid and glutathione S-conjugates: formation and renal activation. Adv Exp Med Biol. 1986; 197:443-55.
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  169. Webb WW, Anders MW. Coupling of ATP synthesis to reversal of rat liver microsomal Ca2+-ATPase. Biochemistry. 1985 Dec 17; 24(26):7741-5.
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  170. Aniya Y, Anders MW. Alteration of hepatic glutathione S-transferases and release into serum after treatment with bromobenzene, carbon tetrachloride, or N-nitrosodimethylamine. Biochem Pharmacol. 1985 Dec 15; 34(24):4239-44.
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  171. Dohn DR, Leininger JR, Lash LH, Quebbemann AJ, Anders MW. Nephrotoxicity of S-(2-chloro-1,1,2-trifluoroethyl)glutathione and S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine, the glutathione and cysteine conjugates of chlorotrifluoroethene. J Pharmacol Exp Ther. 1985 Dec; 235(3):851-7.
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  172. Kitada M, McLenithan JC, Anders MW. Purification and characterization of S-phenacylglutathione reductase from rat liver. J Biol Chem. 1985 Sep 25; 260(21):11749-54.
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  173. Dohn DR, Quebbemann AJ, Borch RF, Anders MW. Enzymatic reaction of chlorotrifluoroethene with glutathione: 19F NMR evidence for stereochemical control of the reaction. Biochemistry. 1985 Sep 10; 24(19):5137-43.
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  174. English JC, Anders MW. Evidence for the metabolism of N-nitrosodimethylamine and carbon tetrachloride by a common isozyme of cytochrome P-450. Drug Metab Dispos. 1985 Jul-Aug; 13(4):449-52.
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  175. Elfarra AA, Baggs RB, Anders MW. Structure-nephrotoxicity relationships of S-(2-chloroethyl)-DL-cysteine and analogs: role for an episulfonium ion. J Pharmacol Exp Ther. 1985 May; 233(2):512-6.
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  176. Aniya Y, Anders MW. Chloroform-induced alteration of glutathione S-transferase activity. Biochem Pharmacol. 1985 Jan 15; 34(2):249-55.
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  177. Anders MW, Jakobson I. Biotransformation of halogenated solvents. Scand J Work Environ Health. 1985; 11 Suppl 1:23-32.
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  178. Elfarra AA, Anders MW. Renal processing of glutathione conjugates. Role in nephrotoxicity. Biochem Pharmacol. 1984 Dec 1; 33(23):3729-32.
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  179. Anders MW, Sunram JM, Wilkinson CF. Mechanism of the metabolism of 1,3-benzodioxoles to carbon monoxide. Biochem Pharmacol. 1984 Feb 15; 33(4):577-80.
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  180. Dohn DR, Anders MW. The enzymatic reaction of chlorotrifluoroethylene with glutathione. Biochem Biophys Res Commun. 1982 Dec 31; 109(4):1339-45.
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  181. Brundin A, Ratnayake JH, Sunram JM, Anders MW. Glutathione-dependent reductive dehalogenation of 2,2',4'-trichloroacetophenone to 2',4'-dichloroacetophenone. Biochem Pharmacol. 1982 Dec 1; 31(23):3885-90.
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  182. Shen ES, Garry VF, Anders MW. Effect of hypoxia on carbon tetrachloride hepatotoxicity. Biochem Pharmacol. 1982 Dec 1; 31(23):3787-93.
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  183. Diamond GL, Anders MW, Tremaine LM, Quebbemann AJ. Salicylate enhancement of renal glucuronide conjugation and tubular excretory transfer of phenols. Drug Metab Dispos. 1982 Nov-Dec; 10(6):573-8.
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  184. Anders MW. Bioactivation of halogenated hydrocarbons. J Toxicol Clin Toxicol. 1982 Aug; 19(6-7):699-706.
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  185. Anders MW, Sunram JM. Transplacental passage of dichloromethane and carbon monoxide. Toxicol Lett. 1982 Aug; 12(4):231-4.
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  186. Livesey JC, Anders MW, Langvardt PW, Putzig CL, Reitz RH. Stereochemistry of the glutathione-dependent biotransformation of vicinal-dihaloalkanes to alkenes. Drug Metab Dispos. 1982 May-Jun; 10(3):201-4.
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  187. Harris RN, Ratnayake JH, Garry VF, Anders MW. Interactive hepatotoxicity of chloroform and carbon tetrachloride. Toxicol Appl Pharmacol. 1982 Apr; 63(2):281-91.
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  188. Dohn DR, Anders MW. Assay of cysteine conjugate beta-lyase activity with S-(2-benzothiazolyl)cysteine as the substrate. Anal Biochem. 1982 Mar 1; 120(2):379-86.
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  189. Swanson AR, Anders MW. Gas chromatographic-mass spectrometric analysis of [13C]carbon monoxide. J Chromatogr. 1982 Jan 1; 234(1):268.
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  190. Harris RN, Anders MW. 2-Propanol treatment induces selectively the metabolism of carbon tetrachloride to phosgene. Implications for carbon tetrachloride hepatotoxicity. Drug Metab Dispos. 1981 Nov-Dec; 9(6):551-6.
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  191. Stevens JL, Anders MW. Metabolism of haloforms to carbon monoxide. IV. studies on the reaction mechanism in vivo. Chem Biol Interact. 1981 Nov; 37(3):365-74.
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  192. Stevens JL, Anders MW. Effect of cysteine, diethyl maleate, and phenobarbital treatments on the hepatotoxicity of [1H]chloroform. Chem Biol Interact. 1981 Oct; 37(1-2):207-17.
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  193. Harris RN, Anders MW. Phosgene: a possible role in the potentiation of carbon tetrachloride hepatotoxicity by 2-propanol. Life Sci. 1981 Aug 3; 29(5):503-7.
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  194. Anders MW, Ratnayake JH, Hanna PE, Fuchs JA. Thioredoxin-dependent sulfoxide reduction by rat renal cytosol. Drug Metab Dispos. 1981 Jul-Aug; 9(4):307-10.
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  195. Kubic VL, Anders MW. Mechanism of the microsomal reduction of carbon tetrachloride and halothane. Chem Biol Interact. 1981 Mar 1; 34(2):201-7.
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  196. Ratnayake JH, Hanna PE, Anders MW, Duggan DE. Sulfoxide reduction. In vitro reduction of sulindac by rat hepatic cytosolic enzymes. Drug Metab Dispos. 1981 Mar-Apr; 9(2):85-7.
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  197. Anders MW, Harris RN. Effect of 2-propanol treatment on carbon tetrachloride metabolism and toxicity. Adv Exp Med Biol. 1981; 136 Pt A:591-602.
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  198. Anders MW, Ratnayake JH, Hanna PE, Fuchs JA. Involvement of thioredoxin in sulfoxide reduction by mammalian tissues. Biochem Biophys Res Commun. 1980 Dec 16; 97(3):846-51.
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  199. Harris RN, Anders MW. Effect of fasting, diethyl maleate, and alcohols on carbon tetrachloride-induced hepatotoxicity. Toxicol Appl Pharmacol. 1980 Nov; 56(2):191-8.
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  200. Ahmed AE, Kubic VL, Stevens JL, Anders MW. Halogenated methanes: metabolism and toxicity. Fed Proc. 1980 Nov; 39(13):3150-5.
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  201. Anders MW. Metabolism of drugs by the kidney. Kidney Int. 1980 Nov; 18(5):636-47.
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  202. Stevens JL, Ratnayake JH, Anders MW. Metabolism of dihalomethanes to carbon monoxide. IV. Studies in isolated rat hepatocytes. Toxicol Appl Pharmacol. 1980 Sep 30; 55(3):484-9.
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  203. Kubic VL, Anders MW. Metabolism of carbon tetrachloride to phosgene. Life Sci. 1980 Jun 23; 26(25):2151-5.
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  204. Yu LS, Wilkinson CF, Anders MW. Generation of carbon monoxide during the microsomal metabolism of methylenedioxyphenyl compounds. Biochem Pharmacol. 1980 Apr 15; 29(8):1113-22.
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  205. Repine JE, Eaton JW, Anders MW, Hoidal JR, Fox RB. Generation of hydroxyl radical by enzymes, chemicals, and human phagocytes in vitro. Detection with the anti-inflammatory agent, dimethyl sulfoxide. J Clin Invest. 1979 Dec; 64(6):1642-51.
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  206. Stevens JL, Anders MW. Metabolism of haloforms to carbon monoxide--III. Studies on the mechanism of the reaction. Biochem Pharmacol. 1979 Nov 1; 28(21):3189-94.
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  207. Anders MW, Gander JE. Acetone enhancement of cumene hydroperoxide supported microsomal aniline hydroxylation. Life Sci. 1979 Sep 17; 25(12):1085-9.
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  208. Livesey JC, Anders MW. In vitro metabolism of 1,2-dihaloethanes to ethylene. Drug Metab Dispos. 1979 Jul-Aug; 7(4):199-203.
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  209. Geisler C, Swanson AR, Zieve L, Anders MW. Phthalate interference in gas-chromatographic determination of long-chain fatty acids in plasma. Clin Chem. 1979 Feb; 25(2):308-10.
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  210. Hanson SK, Anders MW, Montgomery MR. Oxygen metabolism in rabbit bone marrow and liver. Biochem Biophys Res Commun. 1978 Nov 29; 85(2):783-7.
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  211. Anders MW, Stevens JL, Sprague RW, Shaath Z, Ahmed AE. Metabolism of haloforms to carbon monoxide. II. In vivo studies. Drug Metab Dispos. 1978 Sep-Oct; 6(5):556-60.
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  212. Merriman RL, Swanson A, Anders MW, Sladek NE. Microdetermination of caffeine in blood by gas chromatography--mass spectrometry. J Chromatogr. 1978 Jul 1; 146(1):85-90.
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  213. Gammans RE, Sehon RD, Anders MW, Hanna PE. Microsomal N-hydroxylation of trans-4'-alkoxy-4-acetamidostilbenes. Drug Metab Dispos. 1978 May-Jun; 6(3):226-31.
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  214. Anders MW. Inhibition and enhancement of microsomal drug metabolism by diethyl maleate. Biochem Pharmacol. 1978 Apr 1; 27(7):1098-101.
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  215. Lindstrom TD, Anders MW. Effect of agents known to alter carbon tetrachloride hepatotoxicity and cytochrome P-450 levels on carbon tetrachloride-stimulated lipid peroxidation and ethane expiration in the intact rat. Biochem Pharmacol. 1978 Feb 15; 27(4):563-7.
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  216. Lindstrom TD, Anders MW, Remmer H. Effect of phenobarbital and diethyl maleate on carbon tetrachloride toxicity in isolated rat hepatocytes. Exp Mol Pathol. 1978 Feb; 28(1):48-57.
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  217. Ahmed AE, Anders MW. Metabolism of dihalomethanes to formaldehyde and inorganic halide--II. Studies on the mechanism of the reaction. Biochem Pharmacol. 1978; 27(16):2021-5.
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  218. Kubic VL, Anders MW. Metabolism of dihalomethanes to carbon monoxide--III. Studies on the mechanism of the reaction. Biochem Pharmacol. 1978; 27(19):2349-55.
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  219. Rolewicz TF, Mirkin BL, Cooper MJ, Anders MW. Metabolic disposition of cephalothin and deacetylcephalothin in children and adults: comparison of high-performance liquid chromatographic and microbial assay procedures. Clin Pharmacol Ther. 1977 Dec; 22(6):928-35.
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  220. Anders MW, Kubic VL, Ahmed AE. Metabolism of halogenated methanes and macromolecular binding. J Environ Pathol Toxicol. 1977 Nov-Dec; 1(2):117-24.
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  221. Lindstrom TD, Anders MW. Effect of cycloheximide and actinomycin D on carbon tetrachloride hepatotoxicity. Toxicol Appl Pharmacol. 1977 Oct; 42(1):167-73.
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  222. Cooper MJ, Mirkin BL, Anders MW. A rapid micromethod for the high-performance liquid chromatographic determination of theophylline in human serum. J Chromatogr. 1977 May 1; 143(3):324-6.
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  223. Gammans RE, Sehon RD, Anders MW, Hanna PE. Microsomal N-hydroxylation of trans-4'-halo-4-acetamidostilbenes. Drug Metab Dispos. 1977 May-Jun; 5(3):310-6.
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  224. Ahmed AE, Kubic VL, Anders MW. Metabolism of haloforms to carbon monoxide. I. In vitro studies. Drug Metab Dispos. 1977 Mar-Apr; 5(2):198-204.
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  225. Montgomery MR, Wier GT, Zieve FJ, Anders MW. Human intoxication following inhalation exposure to synthetic jet lubricating oil. Clin Toxicol. 1977; 11(4):423-6.
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  226. Ahmed AE, Anders MW. Metabolism of dihalomethanes to formaldehyde and inorganic halide. I. In vitro studies. Drug Metab Dispos. 1976 Jul-Aug; 4(4):357-61.
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  227. Cooper MJ, Sinaiko AR, Anders MW, Mirkin BL. High pressure liquid chromatographic determination of hydrochlorothiazide in human serum and urine. Anal Chem. 1976 Jul; 48(8):1110-1.
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  228. Cooper MJ, Anders MW. High pressure liquid chromatography of fatty acids and lipids. J Chromatogr Sci. 1975 Sep; 13(9):407-11.
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  229. Kubic VL, Anders MW. Metabolism of dihalomethanes to carbon monoxide. II. In vitro studies. Drug Metab Dispos. 1975 Mar-Apr; 3(2):104-12.
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  230. Cooper MJ, anders MW. Gas chromatographic microdetermination of acetanilide in blood. J Chromatogr. 1975 Jan 29; 104(1):215-6.
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  231. Cooper MJ, Anders MW. Metabolic and pharmacodynamic interactions of enantiomers of propoxyphene and methorphan. Life Sci. 1974 Nov 1; 15(9):1665-72.
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  232. Cooper MJ, Anders MW. Determination of long chain fatty acids as 2-naphthacyl esters by high pressure liquid chromatography and mass spectrometry. Anal Chem. 1974 Oct; 46(12):1849-52.
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  233. Hanna PE, Grund VR, Anders MW. Conformationally restricted analogs of histamine H1 receptor antagonists. 2-Phenyl- and 2-benzyl-1,2,3,4-tetrahydro-4-dimethylaminoisoquinoline. J Med Chem. 1974 Sep; 17(9):1020-3.
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  234. Maines MD, Anders MW, Muller-Eberhard U. Studies on heme transfer from microsomal hemoproteins to heme-binding plasma proteins. Mol Pharmacol. 1974 Mar; 10(2):204-13.
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  235. Kubic VL, Anders MW, Engel RR, Barlow CH, Caughey WS. Metabolism of dihalomethanes to carbon monoxide. I. In vivo studies. Drug Metab Dispos. 1974 Jan-Feb; 2(1):53-7.
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  236. Maines MD, Anders MW. Characterization of the heme of cytochrome P-450 using gas chromatography-mass spectrometry. Arch Biochem Biophys. 1973 Nov; 159(1):201-5.
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  237. Rao GH, Anders MW. Aflatoxin detection by high-speed liquid chromatography and mass spectrometry. J Chromatogr. 1973 Sep 26; 84(2):402-6.
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  238. Cooper MJ, Anders MW, Mirkin BL. Ion-pair extraction and high-speed liquid chromatography of cephalothin and deacetylcephalothin in human serum and urine. Drug Metab Dispos. 1973 Sep-Oct; 1(5):659-62.
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  239. Dunham EW, Anders MW. High-speed liquid chromatographic analysis of prostaglandins in rat kidney. Prostaglandins. 1973 Jul; 4(1):85-92.
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  240. Anders MW, Cooper MJ, Takemori AE. Kinetics of microsomal metabolism and binding of enantiomerically related substrates. Drug Metab Dispos. 1973 Jul-Aug; 1(4):642-4.
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  241. Maylin GA, Cooper MJ, Anders MW. Effect of phenobarbital treatment of the sterochemistry of the in vitro metabolism of ethylbenzene. J Med Chem. 1973 Jun; 16(6):606-10.
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  242. Quebbemann AJ, Anders MW. Renal tubular conjugation and excretion of phenol and p-nitrophenol in the chicken: differing mechanisms of renal transfer. J Pharmacol Exp Ther. 1973 Mar; 184(3):695-708.
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  243. Maines MD, Anders MW. Reconstitution of carbon monoxide-binding particles after removal of heme by serum albumin. Mol Pharmacol. 1973 Mar; 9(2):219-28.
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  244. Gundu Rao HR, Anders MW. Inhibition of microsomal drug metabolism by anticholinesterase insecticides. Bull Environ Contam Toxicol. 1973 Jan; 9(1):4-9.
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  245. Maines MD, Anders MW. The possible implication of heme transfer from cytochrome P-420 to albumin in the metabolism of cytochrome P-450. Drug Metab Dispos. 1973 Jan-Feb; 1(1):293-8.
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  246. Anders MW. Effect of phenobarbital and 3-methylcholanthrene administration on the in vitro enhancement of microsomal aromatic hydroxylation. Arch Biochem Biophys. 1972 Dec; 153(2):502-7.
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  247. Anders MW, Latorre JP. High-speed liquid chromatography of glucuronide and sulfate conjugates. J Chromatogr. 1971 Mar 3; 55(2):409-13.
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  248. Anders MW. Enhancement and inhibition of drug metabolism. Annu Rev Pharmacol. 1971; 11:37-56.
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  249. Anders MW, Latorre JP. High-speed ion exchange chromatography of barbiturates, diphenylhydantoin, and their hydroxylated metabolites. Anal Chem. 1970 Oct; 42(12):1430-2.
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  250. Furner RL, McCarthy JS, Stitzel RE, Anders MW. Stereoselective metabolism of the enantiomers of hexobarbital. J Pharmacol Exp Ther. 1969 Oct; 169(2):153-8.
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  251. Anders MW. Stimulation in vitro of microsomal aniline hydroxylation by 2,2'-bipyridine. Biochem Pharmacol. 1969 Oct; 18(10):2561-5.
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  252. Anders MW. Inhibition of microsomal drug metabolism by methylenedioxybenzenes. Biochem Pharmacol. 1968 Nov; 17(11):2367-70.
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  253. Anders MW. Acetone enhancement of microsomal aniline para-hydroxylase activity. Arch Biochem Biophys. 1968 Jul; 126(1):269-75.
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  254. Anders MW, Mannering GJ. Application of gas chromatography to toxicology. Prog Chem Toxicol. 1967; 3:121-218.
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  255. Anders MW. Rapid micromethod for gas chromatographic determination of blood barbiturates. Anal Chem. 1966 Dec; 38(13):1945-7.
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  256. Stitzel RE, Anders MW, Mannering GJ. Inhibition of drug metabolism. 3. Inhibition of hexobarbital metabolism in the intact rat and in the isolated perfused liver by 2-diethylaminoethyl 2,2-diphenylvalerate HC1 (SKF 525-A) and its N-deethylated derivatives. Mol Pharmacol. 1966 Jul; 2(4):335-40.
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  257. Anders MW, Mannering GJ. Inhibition of drug metabolism. I. Kinetics of the inhibition of the N-demethylation of ethylmorphine by 2-diethylaminoethyl 2,2-diphenylvalerate HC1 (SKF 525-A) and related compounds. Mol Pharmacol. 1966 Jul; 2(4):319-27.
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  258. Anders MW, Alvares AP, Mannering GJ. Inhibition of drug metabolism. II. Metabolism of 2-diethylaminoethyl 2,2-diphenylvalerate HC1 (SKF 525-A). Mol Pharmacol. 1966 Jul; 2(4):328-34.
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  259. Anders MW, Mannering GJ. Inhibition of drug metabolism. IV. Induction of drug metabolism by 2-diethylaminoethyl 2,2-diphenylvalerate HC1 (SKF 525-A) and 2,4-dichloro-6-phenylphenoxyethylamine HBr (Lilly 18947) and the effect of induction on the inhibitory properties of SKF 525-A type compounds. Mol Pharmacol. 1966 Jul; 2(4):341-6.
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