URMC Research Network

Find People
Keyword
Last Name
 
More Search Options

Hongyu Miao

TitleAssistant Professor
InstitutionSchool of Medicine and Dentistry
DepartmentBiostatistics and Computational Biology
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 630
Rochester NY 14642
 
 Awards And Honors
      David P. Byar Young Investigator Travel Award  | Biometrics, American Statistical Association
      Provost's Multidisciplinary Award  | University of Rochester
 
 Overview
Quantitative analysis methods, computing techniques and their biological applications have always been of the greatest passion in my work. Currently, a number of biological problems in immunology research interest me, including treatment and vaccination against HIV and influenza infection. To solve these important problems, I have been actively developing a variety of bioinformatics, modeling and data mining methodologies. In the field of computational biology, I specialize in systems immunology, structural bioinformatics and multi-scale complex networks; in the field of statistics, I specialized in parameter estimation of dynamic systems, image analysis, and data mining on manifold; and in the field of mathematical modeling, I specialize in differential equation, stochastic process and probabilistic model.

 
 Selected Publications
List All   |   Timeline
  1. Sanchez-Lockhart M, Rojas AV, Fettis MM, Bauserman R, Higa TR, Miao H, Waugh RE, Miller J. T cell receptor signaling can directly enhance the avidity of CD28 ligand binding. PLoS One. 2014; 9(2):e89263.
    View in: PubMed
  2. Seckler JM, Leioatts N, Miao H, Grossfield A. The interplay of structure and dynamics: Insights from a survey of HIV-1 reverse transcriptase crystal structures. Proteins. 2013 Oct; 81(10):1792-801.
    View in: PubMed
  3. Wang J, Zhang L, Jing C, Ye G, Wu H, Miao H, Wu Y, Zhou X. Multi-scale agent-based modeling on melanoma and its related angiogenesis analysis. Theor Biol Med Model. 2013; 10:41.
    View in: PubMed
  4. Xiao Y, Miao H, Tang S, Wu H. Modeling antiretroviral drug responses for HIV-1 infected patients using differential equation models. Adv Drug Deliv Rev. 2013 Jun 30; 65(7):940-53.
    View in: PubMed
  5. Li X, Miao H, Henn A, Topham DJ, Wu H, Zand MS, Mosmann TR. Ki-67 expression reveals strong, transient influenza specific CD4 T cell responses after adult vaccination. Vaccine. 2012 Jun 29; 30(31):4581-4.
    View in: PubMed
  6. Henn AD, Laski M, Yang H, Welle S, Qiu X, Miao H, Barry CT, Wu H, Zand MS. Functionally Distinct Subpopulations of CpG-Activated Memory B Cells. Sci Rep. 2012; 2:345.
    View in: PubMed
  7. Wu H, Kumar A, Miao H, Holden-Wiltse J, Mosmann TR, Livingstone AM, Belz GT, Perelson AS, Zand MS, Topham DJ. Modeling of influenza-specific CD8+ T cells during the primary response indicates that the spleen is a major source of effectors. J Immunol. 2011 Nov 1; 187(9):4474-82.
    View in: PubMed
  8. Miao H, Jin X, Perelson AS, Wu H. Evaluation of multitype mathematical models for CFSE-labeling experiment data. Bull Math Biol. 2012 Feb; 74(2):300-26.
    View in: PubMed
  9. Miao H, Hollenbaugh JA, Zand MS, Holden-Wiltse J, Mosmann TR, Perelson AS, Wu H, Topham DJ. Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virus. J Virol. 2010 Jul; 84(13):6687-98.
    View in: PubMed
  10. Lee HY, Topham DJ, Park SY, Hollenbaugh J, Treanor J, Mosmann TR, Jin X, Ward BM, Miao H, Holden-Wiltse J, Perelson AS, Zand M, Wu H. Simulation and prediction of the adaptive immune response to influenza A virus infection. J Virol. 2009 Jul; 83(14):7151-65.
    View in: PubMed
  11. Miao H, Gracewski SM, Dalecki D. Ultrasonic excitation of a bubble inside a deformable tube: implications for ultrasonically induced hemorrhage. J Acoust Soc Am. 2008 Oct; 124(4):2374-84.
    View in: PubMed
  12. Miao H, Dykes C, Demeter LM, Cavenaugh J, Park SY, Perelson AS, Wu H. Modeling and estimation of kinetic parameters and replicative fitness of HIV-1 from flow-cytometry-based growth competition experiments. Bull Math Biol. 2008 Aug; 70(6):1749-71.
    View in: PubMed
  13. Miao H, Dykes C, Demeter LM, Wu H. Differential equation modeling of HIV viral fitness experiments: model identification, model selection, and multimodel inference. Biometrics. 2009 Mar; 65(1):292-300.
    View in: PubMed
  14. Wu H, Zhu H, Miao H, Perelson AS. Parameter identifiability and estimation of HIV/AIDS dynamic models. Bull Math Biol. 2008 Apr; 70(3):785-99.
    View in: PubMed
  15. Gracewski SM, Miao H, Dalecki D. Ultrasonic excitation of a bubble near a rigid or deformable sphere: implications for ultrasonically induced hemolysis. J Acoust Soc Am. 2005 Mar; 117(3 Pt 1):1440-7.
    View in: PubMed

Visualizations


Miao's Networks

Concepts
_
Co-Authors
_
Similar People
_
Same Department