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Tatiana Pasternak

TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentNeurobiology and Anatomy
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 603
Rochester NY 14642
Other Positions
TitleProfessor
InstitutionUniversity of Rochester, River Campus
DepartmentBrain/Cognitive Sciences RC

TitleProfessor
InstitutionUniversity of Rochester, River Campus
DepartmentCenter for Visual Science A&S

 
 Overview
My current research is focused on the mechanisms underlying processing and storage of visual motion information in primate cortex. In our studies we combine single cell recordings, microstimulation, reversible inactivation with psychophysical measures of visual performance. We have shown that neurons in visual cortical area MT, strongly associated with processing of visual motion, also participate in the storage and the retrieval/comparison operations required by working memory tasks.

 
 Selected Publications
  • Hussar CR, Pasternak T. Common rules guide comparisons of speed and direction of motion in the dorsolateral prefrontal cortex. J Neurosci. 2013 Jan 16; 33(3):972-86.
    View in: PubMed
  • Hussar CR, Pasternak T. Memory-guided sensory comparisons in the prefrontal cortex: contribution of putative pyramidal cells and interneurons. J Neurosci. 2012 Feb 22; 32(8):2747-61.
    View in: PubMed
  • Lui LL, Pasternak T. Representation of comparison signals in cortical area MT during a delayed direction discrimination task. J Neurophysiol. 2011 Sep; 106(3):1260-73.
    View in: PubMed
  • Hussar C, Pasternak T. Trial-to-trial variability of the prefrontal neurons reveals the nature of their engagement in a motion discrimination task. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21842-7.
    View in: PubMed
  • Hussar CR, Pasternak T. Flexibility of sensory representations in prefrontal cortex depends on cell type. Neuron. 2009 Dec 10; 64(5):730-43.
    View in: PubMed
  • Zaksas D, Pasternak T. Directional signals in the prefrontal cortex and in area MT during a working memory for visual motion task. J Neurosci. 2006 Nov 8; 26(45):11726-42.
    View in: PubMed
  • Zaksas D, Pasternak T. Area MT neurons respond to visual motion distant from their receptive fields. J Neurophysiol. 2005 Dec; 94(6):4156-67.
    View in: PubMed
  • Pasternak T, Greenlee MW. Working memory in primate sensory systems. Nat Rev Neurosci. 2005 Feb; 6(2):97-107.
    View in: PubMed
  • Huxlin KR, Pasternak T. Training-induced recovery of visual motion perception after extrastriate cortical damage in the adult cat. Cereb Cortex. 2004 Jan; 14(1):81-90.
    View in: PubMed
  • Bisley JW, Zaksas D, Droll JA, Pasternak T. Activity of neurons in cortical area MT during a memory for motion task. J Neurophysiol. 2004 Jan; 91(1):286-300.
    View in: PubMed
  • Pasternak T, Zaksas D. Stimulus specificity and temporal dynamics of working memory for visual motion. J Neurophysiol. 2003 Oct; 90(4):2757-62.
    View in: PubMed
  • Zaksas D, Bisley JW, Pasternak T. Motion information is spatially localized in a visual working-memory task. J Neurophysiol. 2001 Aug; 86(2):912-21.
    View in: PubMed
  • Huxlin KR, Pasternak T. Long-term neurochemical changes after visual cortical lesions in the adult cat. J Comp Neurol. 2001 Jan 8; 429(2):221-41.
    View in: PubMed
  • Bisley JW, Zaksas D, Pasternak T. Microstimulation of cortical area MT affects performance on a visual working memory task. J Neurophysiol. 2001 Jan; 85(1):187-96.
    View in: PubMed
  • Bisley JW, Pasternak T. The multiple roles of visual cortical areas MT/MST in remembering the direction of visual motion. Cereb Cortex. 2000 Nov; 10(11):1053-65.
    View in: PubMed
  • Reynolds JH, Pasternak T, Desimone R. Attention increases sensitivity of V4 neurons. Neuron. 2000 Jun; 26(3):703-14.
    View in: PubMed
  • Rudolph K, Pasternak T. Transient and permanent deficits in motion perception after lesions of cortical areas MT and MST in the macaque monkey. Cereb Cortex. 1999 Jan-Feb; 9(1):90-100.
    View in: PubMed
  • Rudolph KK, Pasternak T. Lesions in cat lateral suprasylvian cortex affect the perception of complex motion. Cereb Cortex. 1996 Nov-Dec; 6(6):814-22.
    View in: PubMed
  • Pasternak T, Tompkins J, Olson CR. The role of striate cortex in visual function of the cat. J Neurosci. 1995 Mar; 15(3 Pt 1):1940-50.
    View in: PubMed
  • Rudolph KK, Ferrera VP, Pasternak T. A reduction in the number of directionally selective neurons extends the spatial limit for global motion perception. Vision Res. 1994 Dec; 34(24):3241-51.
    View in: PubMed
  • Pasternak T, Merigan WH. Motion perception following lesions of the superior temporal sulcus in the monkey. Cereb Cortex. 1994 May-Jun; 4(3):247-59.
    View in: PubMed
  • Pasternak T, Maunsell JH. Spatiotemporal sensitivity following lesions of area 18 in the cat. J Neurosci. 1992 Nov; 12(11):4521-9.
    View in: PubMed
  • Pasternak T, Horn K. Spatial vision of the cat: variation with eccentricity. Vis Neurosci. 1991 Feb; 6(2):151-8.
    View in: PubMed
  • Pasternak T, Albano JE, Harvitt DM. The role of directionally selective neurons in the perception of global motion. J Neurosci. 1990 Sep; 10(9):3079-86.
    View in: PubMed
  • Pasternak T, Horn KM, Maunsell JH. Deficits in speed discrimination following lesions of the lateral suprasylvian cortex in the cat. Vis Neurosci. 1989 Oct; 3(4):365-75.
    View in: PubMed
  • Riley NM, Hodos W, Pasternak T. Effects of serial lesions of telencephalic components of the visual system in pigeons. Vis Neurosci. 1988; 1(4):387-94.
    View in: PubMed
  • Pasternak T. Discrimination of differences in speed and flicker rate depends on directionally selective mechanisms. Vision Res. 1987; 27(11):1881-90.
    View in: PubMed
  • Pasternak T, Leinen LJ. Pattern and motion vision in cats with selective loss of cortical directional selectivity. J Neurosci. 1986 Apr; 6(4):938-45.
    View in: PubMed
  • Pasternak T. The role of cortical directional selectivity in detection of motion and flicker. Vision Res. 1986; 26(8):1187-94.
    View in: PubMed
  • Pasternak T, Flood DG, Eskin TA, Merigan WH. Selective damage to large cells in the cat retinogeniculate pathway by 2,5-hexanedione. J Neurosci. 1985 Jun; 5(6):1641-52.
    View in: PubMed
  • Pasternak T, Merigan WH. Effects of stimulus speed on direction discriminations. Vision Res. 1984; 24(10):1349-55.
    View in: PubMed
  • Pasternak T, Merigan WH, Flood DG, Zehl D. The role of area centralis in the spatial vision of the cat. Vision Res. 1983; 23(12):1409-16.
    View in: PubMed
  • Pasternak T, Movshon JA, Merigan WH. Creation of direction selectivity in adult strobe-reared cats. Nature. 1981 Aug 27; 292(5826):834-6.
    View in: PubMed
  • Pasternak T, Merigan WH, Movshon JA. Motion mechanisms in strobe-reared cats: psychophysical and electrophysical measures. Acta Psychol (Amst). 1981 Aug; 48(1-3):321-32.
    View in: PubMed
  • Pasternak T, Merigan WH. The luminance dependence of spatial vision in the cat. Vision Res. 1981; 21(9):1333-9.
    View in: PubMed
  • Pasternak T, Merigan WH. Abnormal visual resolution of cats reared in stroboscopic illumination. Nature. 1979 Jul 26; 280(5720):313-4.
    View in: PubMed
  • Pasternak T, Hodos W. Intensity difference thresholds after lesions of the visual Wulst in pigeons. J Comp Physiol Psychol. 1977 Jun; 91(3):485-97.
    View in: PubMed

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