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Soumyaroop Bhattacharya

TitleSenior Associate
InstitutionSchool of Medicine and Dentistry
DepartmentPediatrics
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 651
Rochester NY 14642
 
 Awards And Honors
      Travel Fellowship  | International Society of Computational Biology
      Best E-Poster  | Association of Pathology Informatics
      Graduate Research Grant Award  | University of Massachusetts
      National Talent Search Scholarship  | NCERT
 
 Overview
Soumyaroop Bhattacharya is a Senior Associate in Neonatology Division of Pediatrics Department. His research interests include gene expression analysis of lung development and diseases, involving biomarker discovery and algorithm development for data analysis, and he is currently leading multiple projects on Genom-wide expression profiling studies on lung diseases and development. He is also collaborating with investigators in numerous other bioinformatics studies.
Mr. Bhattacharya has also been involved in development and maintainence 'The Lung Transcriptome' (http://lungtranscriptome.bwh.harvard.edu), a web resource for pulmonary genomics, which provides expression microarray databases and analytical tools to the lung research community.

 
 Selected Publications
List All   |   Timeline
  1. Bhattacharya S, Mariani TJ. Systems biology approaches to identify developmental bases for lung diseases. Pediatr Res. 2013 Apr; 73(4 Pt 2):514-22.
    View in: PubMed
  2. Bhattacharya S, Go D, Krenitsky DL, Huyck HL, Solleti SK, Lunger VA, Metlay L, Srisuma S, Wert SE, Mariani TJ, Pryhuber GS. Genome-wide transcriptional profiling reveals connective tissue mast cell accumulation in bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2012 Aug 15; 186(4):349-58.
    View in: PubMed
  3. Brehm JM, Hagiwara K, Tesfaigzi Y, Bruse S, Mariani TJ, Bhattacharya S, Boutaoui N, Ziniti JP, Soto-Quiros ME, Avila L, Cho MH, Himes B, Litonjua AA, Jacobson F, Bakke P, Gulsvik A, Anderson WH, Lomas DA, Forno E, Datta S, Silverman EK, Celedón JC. Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. Thorax. 2011 Dec; 66(12):1085-90.
    View in: PubMed
  4. Bhattacharya S, Tyagi S, Srisuma S, Demeo DL, Shapiro SD, Bueno R, Silverman EK, Reilly JJ, Mariani TJ. Peripheral blood gene expression profiles in COPD subjects. J Clin Bioinforma. 2011; 1(1):12.
    View in: PubMed
  5. Hersh CP, Silverman EK, Gascon J, Bhattacharya S, Klanderman BJ, Litonjua AA, Lefebvre V, Sparrow D, Reilly JJ, Anderson WH, Lomas DA, Mariani TJ. SOX5 is a candidate gene for chronic obstructive pulmonary disease susceptibility and is necessary for lung development. Am J Respir Crit Care Med. 2011 Jun 1; 183(11):1482-9.
    View in: PubMed
  6. Srisuma S, Bhattacharya S, Simon DM, Solleti SK, Tyagi S, Starcher B, Mariani TJ. Fibroblast growth factor receptors control epithelial-mesenchymal interactions necessary for alveolar elastogenesis. Am J Respir Crit Care Med. 2010 Apr 15; 181(8):838-50.
    View in: PubMed
  7. Kho AT, Bhattacharya S, Tantisira KG, Carey VJ, Gaedigk R, Leeder JS, Kohane IS, Weiss ST, Mariani TJ. Transcriptomic analysis of human lung development. Am J Respir Crit Care Med. 2010 Jan 1; 181(1):54-63.
    View in: PubMed
  8. DeMeo DL, Mariani T, Bhattacharya S, Srisuma S, Lange C, Litonjua A, Bueno R, Pillai SG, Lomas DA, Sparrow D, Shapiro SD, Criner GJ, Kim HP, Chen Z, Choi AM, Reilly J, Silverman EK. Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am J Hum Genet. 2009 Oct; 85(4):493-502.
    View in: PubMed
  9. Bhattacharya S, Mariani TJ. Array of hope: expression profiling identifies disease biomarkers and mechanism. Biochem Soc Trans. 2009 Aug; 37(Pt 4):855-62.
    View in: PubMed
  10. Du R, Tantisira K, Carey V, Bhattacharya S, Metje S, Kho AT, Klanderman BJ, Gaedigk R, Lazarus R, Mariani TJ, Leeder JS, Weiss ST. Platform dependence of inference on gene-wise and gene-set involvement in human lung development. BMC Bioinformatics. 2009; 10:189.
    View in: PubMed
  11. Bhattacharya S, Srisuma S, Demeo DL, Shapiro SD, Bueno R, Silverman EK, Reilly JJ, Mariani TJ. Molecular biomarkers for quantitative and discrete COPD phenotypes. Am J Respir Cell Mol Biol. 2009 Mar; 40(3):359-67.
    View in: PubMed
  12. Kho AT, Bhattacharya S, Mecham BH, Hong J, Kohane IS, Mariani TJ. Expression profiles of the mouse lung identify a molecular signature of time-to-birth. Am J Respir Cell Mol Biol. 2009 Jan; 40(1):47-57.
    View in: PubMed
  13. Craig FE, Johnson LR, Harvey SA, Nalesnik MA, Luo JH, Bhattacharya SD, Swerdlow SH. Gene expression profiling of Epstein-Barr virus-positive and -negative monomorphic B-cell posttransplant lymphoproliferative disorders. Diagn Mol Pathol. 2007 Sep; 16(3):158-68.
    View in: PubMed
  14. MacDonald TJ, Pollack IF, Okada H, Bhattacharya S, Lyons-Weiler J. Progression-associated genes in astrocytoma identified by novel microarray gene expression data reanalysis. Methods Mol Biol. 2007; 377:203-22.
    View in: PubMed
  15. Bhattacharya S, Srisuma S, Demeo DL, Reilly JJ, Bueno R, Silverman EK, Mariani TJ. Microarray data-based prioritization of chronic obstructive pulmonary disease susceptibility genes. Proc Am Thorac Soc. 2006 Aug; 3(6):472.
    View in: PubMed
  16. Simon DM, Arikan MC, Srisuma S, Bhattacharya S, Andalcio T, Shapiro SD, Mariani TJ. Epithelial cell PPARgamma is an endogenous regulator of normal lung maturation and maintenance. Proc Am Thorac Soc. 2006 Aug; 3(6):510-1.
    View in: PubMed
  17. Simon DM, Arikan MC, Srisuma S, Bhattacharya S, Tsai LW, Ingenito EP, Gonzalez F, Shapiro SD, Mariani TJ. Epithelial cell PPAR[gamma] contributes to normal lung maturation. FASEB J. 2006 Jul; 20(9):1507-9.
    View in: PubMed
  18. Bhattacharya S, Mariani TJ. Transformation of expression intensities across generations of Affymetrix microarrays using sequence matching and regression modeling. Nucleic Acids Res. 2005; 33(18):e157.
    View in: PubMed
  19. Lyons-Weiler J, Patel S, Bhattacharya S. A classification-based machine learning approach for the analysis of genome-wide expression data. Genome Res. 2003 Mar; 13(3):503-12.
    View in: PubMed
  20. Bhattacharya S, Long D, Lyons-Weiler J. Overcoming confounded controls in the analysis of gene expression data from microarray experiments. Appl Bioinformatics. 2003; 2(4):197-208.
    View in: PubMed

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