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Webster Pilcher

TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentNeurosurgery
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 670
Rochester NY 14642
Other Positions
TitleChairman
InstitutionSchool of Medicine and Dentistry
DepartmentNeurosurgery

 
 Awards And Honors
1983     Alpha Omega Alpha, Honorary Medical Society  | University of Rochester School of Medicine
1986     Resident Research Award  | URMC Department of Surgery
1987     Upjohn Surgical Research Award
2008     Merit Award  | Rochester Academy of Medicine
 
 Selected Publications
  • Johnson MD, O'Connell M, Facik M, Maurer P, Jahromi B, Pilcher W. Cerebrospinal fluid stimulates leptomeningeal and meningioma cell proliferation and activation of STAT3. J Neurooncol. 2012 Mar; 107(1):121-31.
    View in: PubMed
  • Whitehead A, Pilcher W, Champlin D, Nacci D. Common mechanism underlies repeated evolution of extreme pollution tolerance. Proc Biol Sci. 2012 Feb 7; 279(1728):427-33.
    View in: PubMed
  • Johnson MD, O'Connell M, Pilcher W. Lopinavir inhibits meningioma cell proliferation by Akt independent mechanism. J Neurooncol. 2011 Feb; 101(3):441-8.
    View in: PubMed
  • Johnson MD, O'Connell MJ, Pilcher W, Reeder JE. Fibroblast growth factor receptor-3 expression in meningiomas with stimulation of proliferation by the phosphoinositide 3 kinase-Akt pathway. J Neurosurg. 2010 May; 112(5):934-9.
    View in: PubMed
  • Johnson MD, O'Connell MJ, Vito F, Pilcher W. Bone morphogenetic protein 4 and its receptors are expressed in the leptomeninges and meningiomas and signal via the Smad pathway. J Neuropathol Exp Neurol. 2009 Nov; 68(11):1177-83.
    View in: PubMed
  • Biswas T, Okunieff P, Schell MC, Smudzin T, Pilcher WH, Bakos RS, Vates GE, Walter KA, Wensel A, Korones DN, Milano MT. Stereotactic radiosurgery for glioblastoma: retrospective analysis. Radiat Oncol. 2009; 4:11.
    View in: PubMed
  • Oberheim NA, Takano T, Han X, He W, Lin JH, Wang F, Xu Q, Wyatt JD, Pilcher W, Ojemann JG, Ransom BR, Goldman SA, Nedergaard M. Uniquely hominid features of adult human astrocytes. J Neurosci. 2009 Mar 11; 29(10):3276-87.
    View in: PubMed
  • Sim FJ, Lang JK, Ali TA, Roy NS, Vates GE, Pilcher WH, Goldman SA. Statin treatment of adult human glial progenitors induces PPAR gamma-mediated oligodendrocytic differentiation. Glia. 2008 Jul; 56(9):954-62.
    View in: PubMed
  • Johnson VE, Huang JH, Pilcher WH. Special cases: mechanical ventilation of neurosurgical patients. Crit Care Clin. 2007 Apr; 23(2):275-90, x.
    View in: PubMed
  • Sim FJ, Lang JK, Waldau B, Roy NS, Schwartz TE, Pilcher WH, Chandross KJ, Natesan S, Merrill JE, Goldman SA, Goldmanm SA. Complementary patterns of gene expression by human oligodendrocyte progenitors and their environment predict determinants of progenitor maintenance and differentiation. Ann Neurol. 2006 May; 59(5):763-79.
    View in: PubMed
  • Okunieff P, Schell MC, Ruo R, Hale ER, O'Dell WG, Pilcher W. Long-term management of patients with multiple brain metastases after shaped beam radiosurgery. Case report and review of the literature. J Neurosurg. 2004 Nov; 101 Suppl 3:406-12.
    View in: PubMed
  • Hiwatashi A, Danielson B, Moritani T, Bakos RS, Rodenhause TG, Pilcher WH, Westesson PL. Axial loading during MR imaging can influence treatment decision for symptomatic spinal stenosis. AJNR Am J Neuroradiol. 2004 Feb; 25(2):170-4.
    View in: PubMed
  • Lynd-Balta E, Pilcher WH, Joseph SA. AMPA receptor alterations precede mossy fiber sprouting in young children with temporal lobe epilepsy. Neuroscience. 2004; 126(1):105-14.
    View in: PubMed
  • Stroup E, Langfitt J, Berg M, McDermott M, Pilcher W, Como P. Predicting verbal memory decline following anterior temporal lobectomy (ATL). Neurology. 2003 Apr 22; 60(8):1266-73.
    View in: PubMed
  • Yoshiura T, Shrier DA, Pilcher WH, Saunders CA. Case report: Hemispheric juvenile pilocytic astrocytoma with extreme exophytic growth. Clin Radiol. 2001 May; 56(5):427-30.
    View in: PubMed
  • Qian J, Rubio A, Powers JM, Rosenblum MK, Pilcher WH, Shrier DA, Stein BM, Ito M, Iannucci A. Fibro-osseous lesions of the central nervous system: report of four cases and literature review. Am J Surg Pathol. 1999 Oct; 23(10):1270-5.
    View in: PubMed
  • Shrier DA, Melville D, Millet D, Qian J, Millet D, Nelson C, Pilcher W, Powers JM. Fibro-osseous lesions involving the brain: MRI. Neuroradiology. 1999 Jan; 41(1):18-21.
    View in: PubMed
  • Yoshiura T, Shrier DA, Pilcher WH, Rubio A. Cervical spinal meningioma with unusual MR contrast enhancement. AJNR Am J Neuroradiol. 1998 Jun-Jul; 19(6):1040-2.
    View in: PubMed
  • McBride MC, Bronstein KS, Bennett B, Erba G, Pilcher W, Berg MJ. Failure of standard magnetic resonance imaging in patients with refractory temporal lobe epilepsy. Arch Neurol. 1998 Mar; 55(3):346-8.
    View in: PubMed
  • Mullins KJ, Rubio A, Myers SP, Korones DN, Pilcher WH. Malignant ependymomas in a patient with Turcot's syndrome: case report and management guidelines. Surg Neurol. 1998 Mar; 49(3):290-4.
    View in: PubMed
  • Song J, Combs CK, Pilcher WH, Song LY, Utal AK, Coleman PD. Low initial tau phosphorylation in human brain biopsy samples. Neurobiol Aging. 1997 Sep-Oct; 18(5):475-81.
    View in: PubMed
  • Torres CF, Korones DN, Pilcher W. Multiple ependymomas in a patient with Turcot's syndrome. Med Pediatr Oncol. 1997 Jan; 28(1):59-61.
    View in: PubMed
  • Pilcher WH, Langfitt J. Analysis of outcome: temporal lobe resection. Clin Neurosurg. 1997; 44:401-21.
    View in: PubMed
  • Lynd-Balta E, Pilcher WH, Joseph SA. Adrenocorticotropic hormone immunoreactivity in the hippocampal formation of temporal lobe epilepsy patients. Epilepsia. 1996 Nov; 37(11):1081-7.
    View in: PubMed
  • Lynd-Balta E, Pilcher WH, Joseph SA. Distribution of AMPA receptor subunits in the hippocampal formation of temporal lobe epilepsy patients. Neuroscience. 1996 May; 72(1):15-29.
    View in: PubMed
  • Valanne L, Ketonen L, Barsotti J, Peterson P, Pilcher W. Posttraumatic nonfunctioning arm. J Child Neurol. 1995 Jan; 10(1):30-1.
    View in: PubMed
  • Shady JA, Bland LI, Kazee AM, Pilcher WH. Osteoma of the frontoethmoidal sinus with secondary brain abscess and intracranial mucocele: case report. Neurosurgery. 1994 May; 34(5):920-3; discussion 923.
    View in: PubMed
  • Prasad AV, Pilcher WH, Joseph SA. Nuclear factor-kappa B in rat brain: enhanced DNA-binding activity following convulsant-induced seizures. Neurosci Lett. 1994 Mar 28; 170(1):145-8.
    View in: PubMed
  • Pilcher WH, Silbergeld DL, Berger MS, Ojemann GA. Intraoperative electrocorticography during tumor resection: impact on seizure outcome in patients with gangliogliomas. J Neurosurg. 1993 Jun; 78(6):891-902.
    View in: PubMed
  • Pilcher WH, Rusyniak WG. Complications of epilepsy surgery. Neurosurg Clin N Am. 1993 Apr; 4(2):311-25.
    View in: PubMed
  • Radley MG, McDonald JV, Pilcher WH, Wilbur DC. Late solitary cerebral metastases from renal cell carcinoma: report of two cases. Surg Neurol. 1993 Mar; 39(3):230-4.
    View in: PubMed
  • Rusyniak WG, Ireland PD, Radley MG, Pilcher WH, Okawara SH. Ultrasonographic and electrophysiological adjuncts to surgery within the brain stem: technical note. Neurosurgery. 1992 Oct; 31(4):798-800; discussion 800-1.
    View in: PubMed
  • Rusyniak WG, Peterson PC, Okawara SH, Pilcher WH, George ED. Acute subdural hematoma after aneurysmal rupture; evacuation with aneurysmal clipping after emergent infusion computed tomography: case report. Neurosurgery. 1992 Jul; 31(1):129-31; discussion 131-2.
    View in: PubMed
  • Vossler DG, Wilkus RJ, Pilcher WH, Farwell JR. Epilepsy in schizencephaly: abnormal cortical organization studied by somatosensory evoked potentials. Epilepsia. 1992 May-Jun; 33(3):487-94.
    View in: PubMed
  • Pilcher WH, Locharernkul C, Primrose D, Ojemann LM, Ojemann GA. Update in epilepsy. Part III: Surgical therapy of intractable epilepsy. N Y State J Med. 1992 Mar; 92(3):92-6.
    View in: PubMed
  • Primrose D, Locharernkul C, Pilcher WH, Ojemann LM, Ojemann GA. Special considerations in the treatment of epilepsy. N Y State J Med. 1992 Feb; 92(2):53-6.
    View in: PubMed
  • Locharernkul C, Primrose D, Pilcher WH, Ojemann LM, Ojemann GA. Update in epilepsy. Part I: Diagnosis and treatment of epilepsy. N Y State J Med. 1992 Jan; 92(1):14-7.
    View in: PubMed
  • LeRoux PD, Berger MS, Haglund MM, Pilcher WH, Ojemann GA. Resection of intrinsic tumors from nondominant face motor cortex using stimulation mapping: report of two cases. Surg Neurol. 1991 Jul; 36(1):44-8.
    View in: PubMed
  • Joseph SA, Pilcher WH, Knigge KM, Abood LG, Michael GJ. Arginine vasopressin-anti-idiotypic immunostaining of human brain cells. J Neuroendocrinol. 1990 Oct 1; 2(5):659-65.
    View in: PubMed
  • Pilcher WH, Joseph SA, McDonald JV. Immunocytochemical localization of pro-opiomelanocortin neurons in human brain areas subserving stimulation analgesia. J Neurosurg. 1988 Apr; 68(4):621-9.
    View in: PubMed
  • Pilcher WH, Joseph SA. Differential sensitivity of hypothalamic and medullary opiocortin and tyrosine hydroxylase neurons to the neurotoxic effects of monosodium glutamate (MSG). Peptides. 1986 Sep-Oct; 7(5):783-9.
    View in: PubMed
  • Almqvist PM, Knigge KM, Kuenzig M, Joseph SA, Pilcher WH, Schwartz SI. Pulmonary platelet trapping induced by beta-endorphin injection in the cerebrospinal fluid in dogs. Surgery. 1985 Aug; 98(2):344-9.
    View in: PubMed
  • Joseph SA, Pilcher WH, Knigge KM. Anatomy of the corticotropin-releasing factor and opiomelanocortin systems of the brain. Fed Proc. 1985 Jan; 44(1 Pt 1):100-7.
    View in: PubMed
  • Warren PH, Pilcher W, Coopersmith R. Stressors produce a concurrent decrease and increase in reflex amplitude in rats treated with naloxone. Life Sci. 1984 Sep 24; 35(13):1409-14.
    View in: PubMed
  • Pilcher WH, Joseph SA. Co-localization of CRF-ir perikarya and ACTH-ir fibers in rat brain. Brain Res. 1984 May 7; 299(1):91-102.
    View in: PubMed
  • Joseph SA, Pilcher WH, Bennett-Clarke C. Immunocytochemical localization of ACTH perikarya in nucleus tractus solitarius: evidence for a second opiocortin neuronal system. Neurosci Lett. 1983 Aug 8; 38(3):221-5.
    View in: PubMed
  • Romagnano MA, Chafel TL, Pilcher WH, Joseph SA. The distribution of enkephalin in the mediobasal hypothalamus of the mouse brain: effects of neonatal administration of MSG. Brain Res. 1982 Mar 25; 236(2):497-504.
    View in: PubMed
  • Romagnano MA, Pilcher WH, Bennett-Clarke C, Chafel TL, Joseph SA. Distribution of somatostatin in the mouse brain: effects of neonatal MSG treatment. Brain Res. 1982 Feb 25; 234(2):387-98.
    View in: PubMed

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