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Danielle Benoit

TitleAssistant Professor
InstitutionUniversity of Rochester, River Campus
DepartmentBiomedical Engineering
AddressUniversity of Rochester
500 Joseph C. Wilson Blvd.
Box 270168
Rochester NY 14611
Other Positions
TitleAssistant Professor
InstitutionUniversity of Rochester Medical Center
DepartmentCenter for Musculoskeletal Research

 
 Selected Publications
  • Benoit DS, Boutin ME. Controlling Mesenchymal Stem Cell Gene Expression Using Polymer-Mediated Delivery of siRNA. Biomacromolecules. 2012 Nov 12; 13(11):3841-9.
    View in: PubMed
  • Arany S, Xu Q, Hernady E, Benoit DS, Dewhurst S, Ovitt CE. Pro-apoptotic gene knockdown mediated by nanocomplexed siRNA reduces radiation damage in primary salivary gland cultures. J Cell Biochem. 2012 Jun; 113(6):1955-65.
    View in: PubMed
  • Benoit DS, Srinivasan S, Shubin AD, Stayton PS. Synthesis of folate-functionalized RAFT polymers for targeted siRNA delivery. Biomacromolecules. 2011 Jul 11; 12(7):2708-14.
    View in: PubMed
  • Benoit DS, Henry SM, Shubin AD, Hoffman AS, Stayton PS. pH-responsive polymeric sirna carriers sensitize multidrug resistant ovarian cancer cells to doxorubicin via knockdown of polo-like kinase 1. Mol Pharm. 2010 Apr 5; 7(2):442-55.
    View in: PubMed
  • Duvall CL, Convertine AJ, Benoit DS, Hoffman AS, Stayton PS. Intracellular delivery of a proapoptotic peptide via conjugation to a RAFT synthesized endosomolytic polymer. Mol Pharm. 2010 Apr 5; 7(2):468-76.
    View in: PubMed
  • Henry SM, Convertine AJ, Benoit DS, Hoffman AS, Stayton PS. End-functionalized polymers and junction-functionalized diblock copolymers via RAFT chain extension with maleimido monomers. Bioconjug Chem. 2009 Jun; 20(6):1122-8.
    View in: PubMed
  • Convertine AJ, Benoit DS, Duvall CL, Hoffman AS, Stayton PS. Development of a novel endosomolytic diblock copolymer for siRNA delivery. J Control Release. 2009 Feb 10; 133(3):221-9.
    View in: PubMed
  • Benoit DS, Schwartz MP, Durney AR, Anseth KS. Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells. Nat Mater. 2008 Oct; 7(10):816-23.
    View in: PubMed
  • Rydholm AE, Held NL, Benoit DS, Bowman CN, Anseth KS. Modifying network chemistry in thiol-acrylate photopolymers through postpolymerization functionalization to control cell-material interactions. J Biomed Mater Res A. 2008 Jul; 86(1):23-30.
    View in: PubMed
  • Benoit DS, Tripodi MC, Blanchette JO, Langer SJ, Leinwand LA, Anseth KS. Integrin-linked kinase production prevents anoikis in human mesenchymal stem cells. J Biomed Mater Res A. 2007 May; 81(2):259-68.
    View in: PubMed
  • Benoit DS, Durney AR, Anseth KS. The effect of heparin-functionalized PEG hydrogels on three-dimensional human mesenchymal stem cell osteogenic differentiation. Biomaterials. 2007 Jan; 28(1):66-77.
    View in: PubMed
  • Benoit DS, Nuttelman CR, Collins SD, Anseth KS. Synthesis and characterization of a fluvastatin-releasing hydrogel delivery system to modulate hMSC differentiation and function for bone regeneration. Biomaterials. 2006 Dec; 27(36):6102-10.
    View in: PubMed
  • Benoit DS, Durney AR, Anseth KS. Manipulations in hydrogel degradation behavior enhance osteoblast function and mineralized tissue formation. Tissue Eng. 2006 Jun; 12(6):1663-73.
    View in: PubMed
  • Benoit DS, Anseth KS. The effect on osteoblast function of colocalized RGD and PHSRN epitopes on PEG surfaces. Biomaterials. 2005 Sep; 26(25):5209-20.
    View in: PubMed
  • Nuttelman CR, Benoit DS, Tripodi MC, Anseth KS. The effect of ethylene glycol methacrylate phosphate in PEG hydrogels on mineralization and viability of encapsulated hMSCs. Biomaterials. 2006 Mar; 27(8):1377-86.
    View in: PubMed
  • Benoit DS, Anseth KS. Heparin functionalized PEG gels that modulate protein adsorption for hMSC adhesion and differentiation. Acta Biomater. 2005 Jul; 1(4):461-70.
    View in: PubMed

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