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Van Alst NE, Sherrill LA, Iglewski BH, Haidaris CG. Compensatory periplasmic nitrate reductase activity supports anaerobic growth of Pseudomonas aeruginosa PAO1 in the absence of membrane nitrate reductase. Can J Microbiol. 2009 Oct; 55(10):1133-44.
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Van Alst NE, Wellington M, Clark VL, Haidaris CG, Iglewski BH. Nitrite reductase NirS is required for type III secretion system expression and virulence in the human monocyte cell line THP-1 by Pseudomonas aeruginosa. Infect Immun. 2009 Oct; 77(10):4446-54.
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Wagner VE, Iglewski BH. P. aeruginosa Biofilms in CF Infection. Clin Rev Allergy Immunol. 2008 Dec; 35(3):124-34.
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Morici LA, Carterson AJ, Wagner VE, Frisk A, Schurr JR, Höner zu Bentrup K, Hassett DJ, Iglewski BH, Sauer K, Schurr MJ. Pseudomonas aeruginosa AlgR represses the Rhl quorum-sensing system in a biofilm-specific manner. J Bacteriol. 2007 Nov; 189(21):7752-64.
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Van Alst NE, Picardo KF, Iglewski BH, Haidaris CG. Nitrate sensing and metabolism modulate motility, biofilm formation, and virulence in Pseudomonas aeruginosa. Infect Immun. 2007 Aug; 75(8):3780-90.
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Li LL, Malone JE, Iglewski BH. Regulation of the Pseudomonas aeruginosa quorum-sensing regulator VqsR. J Bacteriol. 2007 Jun; 189(12):4367-74.
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Wagner VE, Li LL, Isabella VM, Iglewski BH. Analysis of the hierarchy of quorum-sensing regulation in Pseudomonas aeruginosa. Anal Bioanal Chem. 2007 Jan; 387(2):469-79.
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Matsui H, Wagner VE, Hill DB, Schwab UE, Rogers TD, Button B, Taylor RM, Superfine R, Rubinstein M, Iglewski BH, Boucher RC. A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms. Proc Natl Acad Sci U S A. 2006 Nov 28; 103(48):18131-6.
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Filiatrault MJ, Picardo KF, Ngai H, Passador L, Iglewski BH. Identification of Pseudomonas aeruginosa genes involved in virulence and anaerobic growth. Infect Immun. 2006 Jul; 74(7):4237-45.
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Wagner VE, Frelinger JG, Barth RK, Iglewski BH. Quorum sensing: dynamic response of Pseudomonas aeruginosa to external signals. Trends Microbiol. 2006 Feb; 14(2):55-8.
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Gillis RJ, White KG, Choi KH, Wagner VE, Schweizer HP, Iglewski BH. Molecular basis of azithromycin-resistant Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother. 2005 Sep; 49(9):3858-67.
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Filiatrault MJ, Wagner VE, Bushnell D, Haidaris CG, Iglewski BH, Passador L. Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa. Infect Immun. 2005 Jun; 73(6):3764-72.
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Imamura Y, Higashiyama Y, Tomono K, Izumikawa K, Yanagihara K, Ohno H, Miyazaki Y, Hirakata Y, Mizuta Y, Kadota J, Iglewski BH, Kohno S. Azithromycin exhibits bactericidal effects on Pseudomonas aeruginosa through interaction with the outer membrane. Antimicrob Agents Chemother. 2005 Apr; 49(4):1377-80.
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Wagner VE, Gillis RJ, Iglewski BH. Transcriptome analysis of quorum-sensing regulation and virulence factor expression in Pseudomonas aeruginosa. Vaccine. 2004 Dec 6; 22 Suppl 1:S15-20.
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Gillis RJ, Iglewski BH. Azithromycin retards Pseudomonas aeruginosa biofilm formation. J Clin Microbiol. 2004 Dec; 42(12):5842-5.
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Lamb JR, Patel H, Montminy T, Wagner VE, Iglewski BH. Functional domains of the RhlR transcriptional regulator of Pseudomonas aeruginosa. J Bacteriol. 2003 Dec; 185(24):7129-39.
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Smith RS, Iglewski BH. Pseudomonas aeruginosa quorum sensing as a potential antimicrobial target. J Clin Invest. 2003 Nov; 112(10):1460-5.
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Wagner VE, Bushnell D, Passador L, Brooks AI, Iglewski BH. Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment. J Bacteriol. 2003 Apr; 185(7):2080-95.
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Smith RS, Iglewski BH. P. aeruginosa quorum-sensing systems and virulence. Curr Opin Microbiol. 2003 Feb; 6(1):56-60.
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Yoon SS, Hennigan RF, Hilliard GM, Ochsner UA, Parvatiyar K, Kamani MC, Allen HL, DeKievit TR, Gardner PR, Schwab U, Rowe JJ, Iglewski BH, McDermott TR, Mason RP, Wozniak DJ, Hancock RE, Parsek MR, Noah TL, Boucher RC, Hassett DJ. Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis. Dev Cell. 2002 Oct; 3(4):593-603.
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Smith RS, Kelly R, Iglewski BH, Phipps RP. The Pseudomonas autoinducer N-(3-oxododecanoyl) homoserine lactone induces cyclooxygenase-2 and prostaglandin E2 production in human lung fibroblasts: implications for inflammation. J Immunol. 2002 Sep 1; 169(5):2636-42.
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de Kievit TR, Kakai Y, Register JK, Pesci EC, Iglewski BH. Role of the Pseudomonas aeruginosa las and rhl quorum-sensing systems in rhlI regulation. FEMS Microbiol Lett. 2002 Jun 18; 212(1):101-6.
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Smith RS, Harris SG, Phipps R, Iglewski B. The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)homoserine lactone contributes to virulence and induces inflammation in vivo. J Bacteriol. 2002 Feb; 184(4):1132-9.
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Smith RS, Fedyk ER, Springer TA, Mukaida N, Iglewski BH, Phipps RP. IL-8 production in human lung fibroblasts and epithelial cells activated by the Pseudomonas autoinducer N-3-oxododecanoyl homoserine lactone is transcriptionally regulated by NF-kappa B and activator protein-2. J Immunol. 2001 Jul 1; 167(1):366-74.
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De Kievit TR, Parkins MD, Gillis RJ, Srikumar R, Ceri H, Poole K, Iglewski BH, Storey DG. Multidrug efflux pumps: expression patterns and contribution to antibiotic resistance in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother. 2001 Jun; 45(6):1761-70.
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De Kievit TR, Gillis R, Marx S, Brown C, Iglewski BH. Quorum-sensing genes in Pseudomonas aeruginosa biofilms: their role and expression patterns. Appl Environ Microbiol. 2001 Apr; 67(4):1865-73.
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Bollinger N, Hassett DJ, Iglewski BH, Costerton JW, McDermott TR. Gene expression in Pseudomonas aeruginosa: evidence of iron override effects on quorum sensing and biofilm-specific gene regulation. J Bacteriol. 2001 Mar; 183(6):1990-6.
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Branny P, Pearson JP, Pesci EC, Köhler T, Iglewski BH, Van Delden C. Inhibition of quorum sensing by a Pseudomonas aeruginosa dksA homologue. J Bacteriol. 2001 Mar; 183(5):1531-9.
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de Kievit TR, Iglewski BH. Bacterial quorum sensing in pathogenic relationships. Infect Immun. 2000 Sep; 68(9):4839-49.
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Rashid MH, Rumbaugh K, Passador L, Davies DG, Hamood AN, Iglewski BH, Kornberg A. Polyphosphate kinase is essential for biofilm development, quorum sensing, and virulence of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 2000 Aug 15; 97(17):9636-41.
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Pearson JP, Feldman M, Iglewski BH, Prince A. Pseudomonas aeruginosa cell-to-cell signaling is required for virulence in a model of acute pulmonary infection. Infect Immun. 2000 Jul; 68(7):4331-4.
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McKnight SL, Iglewski BH, Pesci EC. The Pseudomonas quinolone signal regulates rhl quorum sensing in Pseudomonas aeruginosa. J Bacteriol. 2000 May; 182(10):2702-8.
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Kline T, Bowman J, Iglewski BH, de Kievit T, Kakai Y, Passador L. Novel synthetic analogs of the Pseudomonas autoinducer. Bioorg Med Chem Lett. 1999 Dec 20; 9(24):3447-52.
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Hassett DJ, Ma JF, Elkins JG, McDermott TR, Ochsner UA, West SE, Huang CT, Fredericks J, Burnett S, Stewart PS, McFeters G, Passador L, Iglewski BH. Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide. Mol Microbiol. 1999 Dec; 34(5):1082-93.
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Rumbaugh KP, Griswold JA, Iglewski BH, Hamood AN. Contribution of quorum sensing to the virulence of Pseudomonas aeruginosa in burn wound infections. Infect Immun. 1999 Nov; 67(11):5854-62.
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Pesci EC, Milbank JB, Pearson JP, McKnight S, Kende AS, Greenberg EP, Iglewski BH. Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 1999 Sep 28; 96(20):11229-34.
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de Kievit T, Seed PC, Nezezon J, Passador L, Iglewski BH. RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa. J Bacteriol. 1999 Apr; 181(7):2175-84.
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Glessner A, Smith RS, Iglewski BH, Robinson JB. Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of twitching motility. J Bacteriol. 1999 Mar; 181(5):1623-9.
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Pearson JP, Van Delden C, Iglewski BH. Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals. J Bacteriol. 1999 Feb; 181(4):1203-10.
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De Kievit TR, Iglewski BH. Quorum sensing, gene expression, and Pseudomonas biofilms. Methods Enzymol. 1999; 310:117-28.
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Van Delden C, Iglewski BH. Cell-to-cell signaling and Pseudomonas aeruginosa infections. Emerg Infect Dis. 1998 Oct-Dec; 4(4):551-60.
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Van Delden C, Pesci EC, Pearson JP, Iglewski BH. Starvation selection restores elastase and rhamnolipid production in a Pseudomonas aeruginosa quorum-sensing mutant. Infect Immun. 1998 Sep; 66(9):4499-502.
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Davies DG, Parsek MR, Pearson JP, Iglewski BH, Costerton JW, Greenberg EP. The involvement of cell-to-cell signals in the development of a bacterial biofilm. Science. 1998 Apr 10; 280(5361):295-8.
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Pearson JP, Pesci EC, Iglewski BH. Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes. J Bacteriol. 1997 Sep; 179(18):5756-67.
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Preston MJ, Seed PC, Toder DS, Iglewski BH, Ohman DE, Gustin JK, Goldberg JB, Pier GB. Contribution of proteases and LasR to the virulence of Pseudomonas aeruginosa during corneal infections. Infect Immun. 1997 Aug; 65(8):3086-90.
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Albus AM, Pesci EC, Runyen-Janecky LJ, West SE, Iglewski BH. Vfr controls quorum sensing in Pseudomonas aeruginosa. J Bacteriol. 1997 Jun; 179(12):3928-35.
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Pesci EC, Pearson JP, Seed PC, Iglewski BH. Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa. J Bacteriol. 1997 May; 179(10):3127-32.
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Pesci EC, Iglewski BH. The chain of command in Pseudomonas quorum sensing. Trends Microbiol. 1997 Apr; 5(4):132-4; discussion 134-5.
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Passador L, Tucker KD, Guertin KR, Journet MP, Kende AS, Iglewski BH. Functional analysis of the Pseudomonas aeruginosa autoinducer PAI. J Bacteriol. 1996 Oct; 178(20):5995-6000.
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Rust L, Pesci EC, Iglewski BH. Analysis of the Pseudomonas aeruginosa elastase (lasB) regulatory region. J Bacteriol. 1996 Feb; 178(4):1134-40.
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Tang HB, DiMango E, Bryan R, Gambello M, Iglewski BH, Goldberg JB, Prince A. Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection. Infect Immun. 1996 Jan; 64(1):37-43.
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Pearson JP, Passador L, Iglewski BH, Greenberg EP. A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1490-4.
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Seed PC, Passador L, Iglewski BH. Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy. J Bacteriol. 1995 Feb; 177(3):654-9.
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Gray KM, Passador L, Iglewski BH, Greenberg EP. Interchangeability and specificity of components from the quorum-sensing regulatory systems of Vibrio fischeri and Pseudomonas aeruginosa. J Bacteriol. 1994 May; 176(10):3076-80.
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Toder DS, Ferrell SJ, Nezezon JL, Rust L, Iglewski BH. lasA and lasB genes of Pseudomonas aeruginosa: analysis of transcription and gene product activity. Infect Immun. 1994 Apr; 62(4):1320-7.
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West SE, Kaye SA, Hamood AN, Iglewski BH. Characterization of Pseudomonas aeruginosa mutants that are deficient in exotoxin A synthesis and are altered in expression of regA, a positive regulator of exotoxin A. Infect Immun. 1994 Mar; 62(3):897-903.
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Pearson JP, Gray KM, Passador L, Tucker KD, Eberhard A, Iglewski BH, Greenberg EP. Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes. Proc Natl Acad Sci U S A. 1994 Jan 4; 91(1):197-201.
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Rust L, Messing CR, Iglewski BH. Elastase assays. Methods Enzymol. 1994; 235:554-62.
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Passador L, Cook JM, Gambello MJ, Rust L, Iglewski BH. Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication. Science. 1993 May 21; 260(5111):1127-30.
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Gambello MJ, Kaye S, Iglewski BH. LasR of Pseudomonas aeruginosa is a transcriptional activator of the alkaline protease gene (apr) and an enhancer of exotoxin A expression. Infect Immun. 1993 Apr; 61(4):1180-4.
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Wick MJ, Cook JM, Iglewski BH. Structure-function analysis of exotoxin A proteins with mutations at histidine 426. Infect Immun. 1992 Mar; 60(3):1128-39.
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Hamood AN, Ohman DE, West SE, Iglewski BH. Isolation and characterization of toxin A excretion-deficient mutants of Pseudomonas aeruginosa PAO1. Infect Immun. 1992 Feb; 60(2):510-7.
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Frank DW, Iglewski BH. Cloning and sequence analysis of a trans-regulatory locus required for exoenzyme S synthesis in Pseudomonas aeruginosa. J Bacteriol. 1991 Oct; 173(20):6460-8.
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Storey DG, Raivio TL, Frank DW, Wick MJ, Kaye S, Iglewski BH. Effect of regB on expression from the P1 and P2 promoters of the Pseudomonas aeruginosa regAB operon. J Bacteriol. 1991 Oct; 173(19):6088-94.
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Toder DS, Gambello MJ, Iglewski BH. Pseudomonas aeruginosa LasA: a second elastase under the transcriptional control of lasR. Mol Microbiol. 1991 Aug; 5(8):2003-10.
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Gambello MJ, Iglewski BH. Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression. J Bacteriol. 1991 May; 173(9):3000-9.
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Mohr CD, Rust L, Albus AM, Iglewski BH, Deretic V. Expression patterns of genes encoding elastase and controlling mucoidy: co-ordinate regulation of two virulence factors in Pseudomonas aeruginosa isolates from cystic fibrosis. Mol Microbiol. 1990 Dec; 4(12):2103-10.
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Olson JC, Hamood AN, Vincent TS, Beachey EH, Iglewski BH. Identification of functional epitopes of Pseudomonas aeruginosa exotoxin A using synthetic peptides and subclone products. Mol Immunol. 1990 Oct; 27(10):981-93.
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Hamood AN, Wick MJ, Iglewski BH. Secretion of toxin A from Pseudomonas aeruginosa PAO1, PAK, and PA103 by Escherichia coli. Infect Immun. 1990 May; 58(5):1133-40.
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Wick MJ, Hamood AN, Iglewski BH. Analysis of the structure-function relationship of Pseudomonas aeruginosa exotoxin A. Mol Microbiol. 1990 Apr; 4(4):527-35.
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Wick MJ, Frank DW, Storey DG, Iglewski BH. Identification of regB, a gene required for optimal exotoxin A yields in Pseudomonas aeruginosa. Mol Microbiol. 1990 Mar; 4(3):489-97.
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Storey DG, Frank DW, Farinha MA, Kropinski AM, Iglewski BH. Multiple promoters control the regulation of the Pseudomonas aeruginosa regA gene. Mol Microbiol. 1990 Mar; 4(3):499-503.
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Hamood AN, Iglewski BH. Expression of the Pseudomonas aeruginosa toxA positive regulatory gene (regA) in Escherichia coli. J Bacteriol. 1990 Feb; 172(2):589-94.
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Wick MJ, Frank DW, Storey DG, Iglewski BH. Structure, function, and regulation of Pseudomonas aeruginosa exotoxin A. Annu Rev Microbiol. 1990; 44:335-63.
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Smith AW, Iglewski BH. Transformation of Pseudomonas aeruginosa by electroporation. Nucleic Acids Res. 1989 Dec 25; 17(24):10509.
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Frank DW, Storey DG, Hindahl MS, Iglewski BH. Differential regulation by iron of regA and toxA transcript accumulation in Pseudomonas aeruginosa. J Bacteriol. 1989 Oct; 171(10):5304-13.
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Zimniak L, Dayn A, Iglewski BH. Identification of RegA protein from Pseudomonas aeruginosa using anti-RegA antibody. Biochem Biophys Res Commun. 1989 Sep 29; 163(3):1312-8.
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Coburn J, Wyatt RT, Iglewski BH, Gill DM. Several GTP-binding proteins, including p21c-H-ras, are preferred substrates of Pseudomonas aeruginosa exoenzyme S. J Biol Chem. 1989 May 25; 264(15):9004-8.
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Hamood AN, Olson JC, Vincent TS, Iglewski BH. Regions of toxin A involved in toxin A excretion in Pseudomonas aeruginosa. J Bacteriol. 1989 Apr; 171(4):1817-24.
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Coburn J, Dillon ST, Iglewski BH, Gill DM. Exoenzyme S of Pseudomonas aeruginosa ADP-ribosylates the intermediate filament protein vimentin. Infect Immun. 1989 Mar; 57(3):996-8.
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Wick MJ, Iglewski BH. Determination of the amino acid change responsible for the nontoxic, cross-reactive exotoxin A protein (CRM 66) of Pseudomonas aeruginosa PAO-PR1. J Bacteriol. 1988 Nov; 170(11):5385-8.
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West SE, Iglewski BH. Codon usage in Pseudomonas aeruginosa. Nucleic Acids Res. 1988 Oct 11; 16(19):9323-35.
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Frank DW, Iglewski BH. Kinetics of toxA and regA mRNA accumulation in Pseudomonas aeruginosa. J Bacteriol. 1988 Oct; 170(10):4477-83.
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Bever RA, Iglewski BH. Molecular characterization and nucleotide sequence of the Pseudomonas aeruginosa elastase structural gene. J Bacteriol. 1988 Sep; 170(9):4309-14.
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Hindahl MS, Frank DW, Hamood A, Iglewski BH. Characterization of a gene that regulates toxin A synthesis in Pseudomonas aeruginosa. Nucleic Acids Res. 1988 Jun 24; 16(12):5699.
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Schad PA, Iglewski BH. Nucleotide sequence and expression in Escherichia coli of the Pseudomonas aeruginosa lasA gene. J Bacteriol. 1988 Jun; 170(6):2784-9.
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Schad PA, Bever RA, Nicas TI, Leduc F, Hanne LF, Iglewski BH. Cloning and characterization of elastase genes from Pseudomonas aeruginosa. J Bacteriol. 1987 Jun; 169(6):2691-6.
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Elsheikh LE, Kronevi T, Wretlind B, Abaas S, Iglewski BH. Assessment of elastase as a Pseudomonas aeruginosa virulence factor in experimental lung infection in mink. Vet Microbiol. 1987 Mar; 13(3):281-9.
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Hindahl MS, Iglewski BH. Cloning and expression of a common Legionella outer membrane antigen in Escherichia coli. Microb Pathog. 1987 Feb; 2(2):91-9.
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Hindahl MS, Frank DW, Iglewski BH. Molecular studies of a positive regulator of toxin A synthesis in Pseudomonas aeruginosa. Antibiot Chemother. 1987; 39:279-89.
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Parmely MJ, Horvat RT, Iglewski BH, Kanarek J, Furtado D, Van Enk R. The antigenicity of a pulmonary pathogen defined by monoclonal T cells. Adv Exp Med Biol. 1987; 216B:1043-51.
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Woodruff WA, Parr TR, Hancock RE, Hanne LF, Nicas TI, Iglewski BH. Expression in Escherichia coli and function of Pseudomonas aeruginosa outer membrane porin protein F. J Bacteriol. 1986 Aug; 167(2):473-9.
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Nicas TI, Iglewski BH. Production of elastase and other exoproducts by environmental isolates of Pseudomonas aeruginosa. J Clin Microbiol. 1986 May; 23(5):967-9.
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Dreyfus LA, Iglewski BH. Purification and characterization of an extracellular protease of Legionella pneumophila. Infect Immun. 1986 Mar; 51(3):736-43.
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Hindahl MS, Iglewski BH. Outer membrane proteins from Legionella pneumophila serogroups and other Legionella species. Infect Immun. 1986 Jan; 51(1):94-101.
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Nicas TI, Bradley J, Lochner JE, Iglewski BH. The role of exoenzyme S in infections with Pseudomonas aeruginosa. J Infect Dis. 1985 Oct; 152(4):716-21.
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Björklind A, Wretlind B, Möllegård I, Schad PA, Iglewski BH, Cox CD. Genetic mapping and characterization of Pseudomonas aeruginosa mutants that hyperproduce exoproteins. J Bacteriol. 1985 Jun; 162(3):1329-31.
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Nicas TI, Iglewski BH. The contribution of exoproducts to virulence of Pseudomonas aeruginosa. Can J Microbiol. 1985 Apr; 31(4):387-92.
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Nicas TI, Frank DW, Stenzel P, Lile JD, Iglewski BH. Role of exoenzyme S in chronic Pseudomonas aeruginosa lung infections. Eur J Clin Microbiol. 1985 Apr; 4(2):175-9.
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Lochner JE, Bigley RH, Iglewski BH. Defective triggering of polymorphonuclear leukocyte oxidative metabolism by Legionella pneumophila toxin. J Infect Dis. 1985 Jan; 151(1):42-6.
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Nicas TI, Iglewski BH. Contribution of exoenzyme S to the virulence of Pseudomonas aeruginosa. Antibiot Chemother. 1985; 36:40-8.
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Nicas TI, Iglewski BH. Genetic approaches to study Pseudomonas aeruginosa protein antigens. Adv Exp Med Biol. 1985; 185:223-32.
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Dreyfus LA, Iglewski BH. Conjugation-mediated genetic exchange in Legionella pneumophila. J Bacteriol. 1985 Jan; 161(1):80-4.
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Parmely MJ, Iglewski BH, Horvat RT. Identification of the principal T lymphocyte-stimulating antigens of Pseudomonas aeruginosa. J Exp Med. 1984 Nov 1; 160(5):1338-49.
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Nicas TI, Iglewski BH. Isolation and characterization of transposon-induced mutants of Pseudomonas aeruginosa deficient in production of exoenzyme S. Infect Immun. 1984 Aug; 45(2):470-4.
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Hindahl MS, Iglewski BH. Isolation and characterization of the Legionella pneumophila outer membrane. J Bacteriol. 1984 Jul; 159(1):107-13.
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Howe TR, Iglewski BH. Isolation and characterization of alkaline protease-deficient mutants of Pseudomonas aeruginosa in vitro and in a mouse eye model. Infect Immun. 1984 Mar; 43(3):1058-63.
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Cryz SJ, Iglewski BH. Toxoids of Pseudomonas aeruginosa toxin A: production by chemical and genetic means. Rev Infect Dis. 1983 Nov-Dec; 5 Suppl 5:S992-7.
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Howe TR, Wretlind B, Iglewski BH. Comparison of two methods of genetic exchange in determination of the genetic locus of the structural gene for Pseudomonas aeruginosa elastase. J Bacteriol. 1983 Oct; 156(1):58-61.
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Woods DE, Iglewski BH. Toxins of Pseudomonas aeruginosa: new perspectives. Rev Infect Dis. 1983 Sep-Oct; 5 Suppl 4:S715-22.
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Hanne LF, Howe TR, Iglewski BH. Locus of the Pseudomonas aeruginosa toxin A gene. J Bacteriol. 1983 Apr; 154(1):383-6.
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Blackwood LL, Stone RM, Iglewski BH, Pennington JE. Evaluation of Pseudomonas aeruginosa exotoxin A and elastase as virulence factors in acute lung infection. Infect Immun. 1983 Jan; 39(1):198-201.
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Lochner JE, Friedman RL, Bigley RH, Iglewski BH. Effect of oxygen-dependent antimicrobial systems on Legionella pneumophila. Infect Immun. 1983 Jan; 39(1):487-9.
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Friedman RL, Lochner JE, Bigley RH, Iglewski BH. The effects of Legionella pneumophila toxin on oxidative processes and bacterial killing of human polymorphonuclear leukocytes. J Infect Dis. 1982 Sep; 146(3):328-34.
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Sokol PA, Cox CD, Iglewski BH. Pseudomonas aeruginosa mutants altered in their sensitivity to the effect of iron on toxin A or elastase yields. J Bacteriol. 1982 Aug; 151(2):783-7.
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Sadoff JC, Buck GA, Iglewski BH, Bjorn MJ, Groman NB. Immunological cross-reactivity in the absence of DNA homology between Pseudomonas toxin A and diphtheria toxin. Infect Immun. 1982 Jul; 37(1):250-4.
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Woods DE, Cryz SJ, Friedman RL, Iglewski BH. Contribution of toxin A and elastase to virulence of Pseudomonas aeruginosa in chronic lung infections of rats. Infect Immun. 1982 Jun; 36(3):1223-8.
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Woods DE, Sokol PA, Iglewski BH. Modulatory effect of iron on the pathogenesis of Pseudomonas aeruginosa mouse corneal infections. Infect Immun. 1982 Feb; 35(2):461-4.
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Friedman RL, Iglewski BH, Roerdink F, Alving CR. Suppression of cytotoxicity of diphtheria toxin by monoclonal antibodies against phosphatidylinositol phosphate. Biophys J. 1982 Jan; 37(1):23-4.
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Hazlett LD, Iglewski BH, Berk RS. Experimental Pseudomonas exotoxin A mediated ocular damage in mouse pups: microscopic observations. Ophthalmic Res. 1982; 14(6):401-8.
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Hazlett LD, Berk RS, Iglewski BH. Microscopic characterization of ocular damage produced by Pseudomonas aeruginosa toxin A. Infect Immun. 1981 Dec; 34(3):1025-35.
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Sokol PA, Iglewski BH, Hager TA, Sadoff JC, Cross AS, McManus A, Farber BF, Iglewski WJ. Production of exoenzyme S by clinical isolates of Pseudomonas aeruginosa. Infect Immun. 1981 Oct; 34(1):147-53.
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Thompson MR, Miller RD, Iglewski BH. In vitro production of an extracellular protease by Legionella pneumophila. Infect Immun. 1981 Oct; 34(1):299-302.
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Berk RS, Iglewski BH, Hazlett LD. Age-related susceptibility of mice to ocular challenge with Pseudomonas aeruginosa exotoxin A. Infect Immun. 1981 Jul; 33(1):90-4.
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Cryz SJ, Friedman RL, Pavlovskis OR, Iglewski BH. Effect of formalin toxoiding on Pseudomonas aeruginosa toxin A: biological, chemical, and immunochemical studies. Infect Immun. 1981 May; 32(2):759-68.
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Cryz SJ, Friedman RL, Iglewski BH. Isolation and characterization of a Pseudomonas aeruginosa mutant producing a nontoxic, immunologically crossreactive toxin A protein. Proc Natl Acad Sci U S A. 1980 Dec; 77(12):7199-203.
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Cross AS, Sadoff JC, Iglewski BH, Sokol PA. Evidence for the role of toxin A in the pathogenesis of infection with Pseudomonas aeruginosa in humans. J Infect Dis. 1980 Oct; 142(4):538-46.
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Ohman DE, Burns RP, Iglewski BH. Corneal infections in mice with toxin A and elastase mutants of Pseudomonas aeruginosa. J Infect Dis. 1980 Oct; 142(4):547-55.
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Cryz SJ, Iglewski BH. Production of alkaline protease by Pseudomonas aeruginosa. J Clin Microbiol. 1980 Jul; 12(1):131-3.
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Friedman RL, Iglewski BH, Miller RD. Identification of a cytotoxin produced by Legionella pneumophila. Infect Immun. 1980 Jul; 29(1):271-4.
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Ohman DE, Cryz SJ, Iglewski BH. Isolation and characterization of Pseudomonas aeruginosa PAO mutant that produces altered elastase. J Bacteriol. 1980 Jun; 142(3):836-42.
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Ohman DE, Sadoff JC, Iglewski BH. Toxin A-deficient mutants of Pseudomonas aeruginosa PA103: isolation and characterization. Infect Immun. 1980 Jun; 28(3):899-908.
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Alving CR, Iglewski BH, Urban KA, Moss J, Richards RL, Sadoff JC. Binding of diphtheria toxin to phospholipids in liposomes. Proc Natl Acad Sci U S A. 1980 Apr; 77(4):1986-90.
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Brodsky WA, Sadoff JC, Durham JH, Ehrenspeck G, Schachner M, Iglewski BH. Effects of pseudomonas toxin A, diphtheria toxin, and cholera toxin on electrical characteristics of turtle bladder. Proc Natl Acad Sci U S A. 1979 Jul; 76(7):3562-6.
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Bjorn MJ, Pavlovskis OR, Thompson MR, Iglewski BH. Production of exoenzyme S during Pseudomonas aeruginosa infections of burned mice. Infect Immun. 1979 Jun; 24(3):837-42.
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Sokol PA, Ohman DE, Iglewski BH. A more sensitive plate assay for detection of protease production by Pseudomanas aeruginosa. J Clin Microbiol. 1979 Apr; 9(4):538-40.
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Bjorn MJ, Sokol PA, Iglewski BH. Influence of iron on yields of extracellular products in Pseudomonas aeruginosa cultures. J Bacteriol. 1979 Apr; 138(1):193-200.
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Iglewski BH, Sadoff JC. Toxin inhibitors of protein synthesis: production, purification, and assay of Pseudomonas aeruginosa toxin A. Methods Enzymol. 1979; 60:780-93.
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Vasil ML, Iglewski BH. Comparative toxicities of diphtherial toxin and Pseudomonas aeruginosa exotoxin A: evidence for different cell receptors. J Gen Microbiol. 1978 Oct; 108(2):333-7.
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Iglewski BH, Sadoff J, Bjorn MJ, Maxwell ES. Pseudomonas aeruginosa exoenzyme S: an adenosine diphosphate ribosyltransferase distinct from toxin A. Proc Natl Acad Sci U S A. 1978 Jul; 75(7):3211-5.
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Bjorn MJ, Iglewski BH, Ives SK, Sadoff JC, Vasil ML. Effect of iron on yields of exotoxin A in cultures of Pseudomonas aeruginosa PA-103. Infect Immun. 1978 Mar; 19(3):785-91.
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Pavlovskis OR, Iglewski BH, Pollack M. Mechanism of action of Pseudomonas aeruginosa exotoxin A in experimental mouse infections: adenosine diphosphate ribosylation of elongation factor 2. Infect Immun. 1978 Jan; 19(1):29-33.
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Pavlovskis OR, Pollack M, Callahan LT, Iglewski BH. Passive protection by antitoxin in experimental Pseudomonas aeruginosa burn infections. Infect Immun. 1977 Dec; 18(3):596-602.
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Vasil ML, Kabat D, Iglewski BH. Structure-activity relationships of an exotoxin of Pseudomonas aeruginosa. Infect Immun. 1977 Apr; 16(1):353-61.
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Bjorn MJ, Vasil ML, Sadoff JC, Iglewski BH. Incidence of exotoxin production by Pseudomonas species. Infect Immun. 1977 Apr; 16(1):362-6.
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Iglewski BH, Liu PV, Kabat D. Mechanism of action of Pseudomonas aeruginosa exotoxin Aiadenosine diphosphate-ribosylation of mammalian elongation factor 2 in vitro and in vivo. Infect Immun. 1977 Jan; 15(1):138-44.
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Iglewski BH, Burns RP, Gipson IK. Pathogenesis of corneal damage from pseudomonas exotoxin A. Invest Ophthalmol Vis Sci. 1977 Jan; 16(1):73-6.
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Morse SA, Vaughan P, Johnson D, Iglewski BH. Inhibition of Neisseria gonorrhoeae by a bacteriocin from Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1976 Aug; 10(2):354-62.
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Rittenberg MB, Pinney CT, Iglewski BH. Antigenic relationships on the diphtheria toxin molecule: antitoxin versus antitoxoid. Infect Immun. 1976 Jul; 14(1):122-8.
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Vasil ML, Liu PV, Iglewski BH. Temperature-dependent inactivating factor of Pseudomonas aeruginosa exotoxin A. Infect Immun. 1976 May; 13(5):1467-72.
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Iglewski BH, Kabat D. NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,. Proc Natl Acad Sci U S A. 1975 Jun; 72(6):2284-8.
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Iglewski BH, Rittenberg MB, Iglewski WJ. Preferential inhibition of growth and protein synthesis in Rous sarcoma virus transformed cells by diphtheria toxin. Virology. 1975 May; 65(1):272-5.
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Iglewski BH, Rittenberg MB. Selective toxicity of diphtheria toxin for malignant cells. Proc Natl Acad Sci U S A. 1974 Jul; 71(7):2707-10.
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Lightfoot HN, Iglewski BH. Synthesis of diphtheria toxin in E. coli cell-free lysate. Biochem Biophys Res Commun. 1974 Jan 23; 56(2):351-7.
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Elwell LP, Iglewski BH. Diphtheria toxin: evidence for presence of fragment B in corynebacteriophage. Biochem Biophys Res Commun. 1972 Nov 1; 49(3):609-14.
