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Jan Moynihan

TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentPsychiatry
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box PSYCH
Rochester NY 14642
Other Positions
TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentMicrobiology and Immunology

 
 Awards And Honors
      PHS-declined award  | University of Rochester
      Multiple Sclerosis Society-declined award  | University of Rochester
1972 - 1976Bausch and Lomb Scholar
1976     Wendy Jill Fread Award  | University of Rochester
1984 - 1986Damon Runyon-Walter Winchell Cancer Fund  | University of Rochester
 
 Selected Publications
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  1. Robertson-Blackmore E, Putnam FW, Rubinow DR, Matthieu M, Hunn JE, Putnam KT, Moynihan JA, O'Connor TG. Antecedent trauma exposure and risk of depression in the perinatal period. J Clin Psychiatry. 2013 Oct; 74(10):e942-8.
    View in: PubMed
  2. Knight JM, Lyness JM, Sahler OJ, Liesveld JL, Moynihan JA. Psychosocial factors and hematopoietic stem cell transplantation: Potential biobehavioral pathways. Psychoneuroendocrinology. 2013 Nov; 38(11):2383-93.
    View in: PubMed
  3. Moynihan JA, Chapman BP, Klorman R, Krasner MS, Duberstein PR, Brown KW, Talbot NL. Mindfulness-based stress reduction for older adults: effects on executive function, frontal alpha asymmetry and immune function. Neuropsychobiology. 2013; 68(1):34-43.
    View in: PubMed
  4. Gallegos AM, Hoerger M, Talbot NL, Moynihan JA, Duberstein PR. Emotional benefits of mindfulness-based stress reduction in older adults: the moderating roles of age and depressive symptom severity. Aging Ment Health. 2013 Sep; 17(7):823-9.
    View in: PubMed
  5. Poleshuck EL, Talbot NL, Moynihan JA, Chapman BP, Heffner KL. Depressive Symptoms, Pain, Chronic Medical Morbidity, and Interleukin-6 among Primary Care Patients. Pain Med. 2013 May; 14(5):686-91.
    View in: PubMed
  6. O'Connor TG, Winter MA, Hunn J, Carnahan J, Pressman EK, Glover V, Robertson-Blackmore E, Moynihan JA, Lee FE, Caserta MT. Prenatal maternal anxiety predicts reduced adaptive immunity in infants. Brain Behav Immun. 2013 Aug; 32:21-8.
    View in: PubMed
  7. Gallegos AM, Hoerger M, Talbot NL, Krasner MS, Knight JM, Moynihan JA, Duberstein PR. Toward identifying the effects of the specific components of mindfulness-based stress reduction on biologic and emotional outcomes among older adults. J Altern Complement Med. 2013 Oct; 19(10):787-92.
    View in: PubMed
  8. Vegas O, Vanbuskirk J, Richardson S, Parfitt D, Helmreich D, Rempel M, Moynihan J, Tausk F. Effects of psychological stress and housing conditions on the delay of wound healing. Psicothema. 2012 Nov; 24(4):581-6.
    View in: PubMed
  9. Turiano NA, Mroczek DK, Moynihan J, Chapman BP. Big 5 personality traits and interleukin-6: Evidence for "healthy Neuroticism" in a US population sample. Brain Behav Immun. 2013 Feb; 28:83-9.
    View in: PubMed
  10. Athilingam P, Moynihan J, Chen L, D'Aoust R, Groer M, Kip K. Elevated levels of interleukin 6 and C-reactive protein associated with cognitive impairment in heart failure. Congest Heart Fail. 2013 Mar; 19(2):92-8.
    View in: PubMed
  11. Kobrosly RW, Seplaki CL, Cory-Slechta DA, Moynihan J, van Wijngaarden E. Multisystem physiological dysfunction is associated with depressive symptoms in a population-based sample of older adults. Int J Geriatr Psychiatry. 2013 Jul; 28(7):718-27.
    View in: PubMed
  12. Heffner KL, Ng HM, Suhr JA, France CR, Marshall GD, Pigeon WR, Moynihan JA. Sleep disturbance and older adults' inflammatory responses to acute stress. Am J Geriatr Psychiatry. 2012 Sep; 20(9):744-52.
    View in: PubMed
  13. Pigeon WR, Moynihan J, Matteson-Rusby S, Jungquist CR, Xia Y, Tu X, Perlis ML. Comparative effectiveness of CBT interventions for co-morbid chronic pain & insomnia: a pilot study. Behav Res Ther. 2012 Nov; 50(11):685-9.
    View in: PubMed
  14. Fortin MC, Cory-Slechta DA, Ohman-Strickland P, Nwankwo C, Yanger TS, Todd AC, Moynihan J, Walton J, Brooks A, Fiedler N. Increased lead biomarker levels are associated with changes in hormonal response to stress in occupationally exposed male participants. Environ Health Perspect. 2012 Feb; 120(2):278-83.
    View in: PubMed
  15. Caserta MT, Wyman PA, Wang H, Moynihan J, O'Connor TG. Associations among depression, perceived self-efficacy, and immune function and health in preadolescent children. Dev Psychopathol. 2011 Nov; 23(4):1139-47.
    View in: PubMed
  16. Blackmore ER, Moynihan JA, Rubinow DR, Pressman EK, Gilchrist M, O'Connor TG. Psychiatric symptoms and proinflammatory cytokines in pregnancy. Psychosom Med. 2011 Oct; 73(8):656-63.
    View in: PubMed
  17. Pigeon WR, Heffner K, Duberstein P, Fiscella K, Moynihan J, Chapman BP. Elevated sleep disturbance among blacks in an urban family medicine practice. J Am Board Fam Med. 2011 Mar-Apr; 24(2):161-8.
    View in: PubMed
  18. Rethorst CD, Moynihan J, Lyness JM, Heffner KL, Chapman BP. Moderating effects of moderate-intensity physical activity in the relationship between depressive symptoms and interleukin-6 in primary care patients. Psychosom Med. 2011 Apr; 73(3):265-9.
    View in: PubMed
  19. Chapman BP, van Wijngaarden E, Seplaki CL, Talbot N, Duberstein P, Moynihan J. Openness and conscientiousness predict 34-week patterns of Interleukin-6 in older persons. Brain Behav Immun. 2011 May; 25(4):667-73.
    View in: PubMed
  20. Privitera MR, Moynihan J, Tang W, Khan A. Light therapy for seasonal affective disorder in a clinical office setting. J Psychiatr Pract. 2010 Nov; 16(6):387-93.
    View in: PubMed
  21. Moynihan J, Rieder E, Tausk F. Psychoneuroimmunology: the example of psoriasis. G Ital Dermatol Venereol. 2010 Apr; 145(2):221-8.
    View in: PubMed
  22. Chapman BP, Moynihan J. The brain-skin connection: role of psychosocial factors and neuropeptides in psoriasis. Expert Rev Clin Immunol. 2009 Nov; 5(6):623-7.
    View in: PubMed
  23. Cankaya B, Chapman BP, Talbot NL, Moynihan J, Duberstein PR. History of sudden unexpected loss is associated with elevated interleukin-6 and decreased insulin-like growth factor-1 in women in an urban primary care setting. Psychosom Med. 2009 Nov; 71(9):914-9.
    View in: PubMed
  24. Chapman BP, Khan A, Harper M, Stockman D, Fiscella K, Walton J, Duberstein P, Talbot N, Lyness JM, Moynihan J. Gender, race/ethnicity, personality, and interleukin-6 in urban primary care patients. Brain Behav Immun. 2009 Jul; 23(5):636-42.
    View in: PubMed
  25. Caserta MT, O'Connor TG, Wyman PA, Wang H, Moynihan J, Cross W, Tu X, Jin X. The associations between psychosocial stress and the frequency of illness, and innate and adaptive immune function in children. Brain Behav Immun. 2008 Aug; 22(6):933-40.
    View in: PubMed
  26. Tausk F, Elenkov I, Moynihan J. Psychoneuroimmunology. Dermatol Ther. 2008 Jan-Feb; 21(1):22-31.
    View in: PubMed
  27. Moynihan JA, Santiago FM. Brain behavior and immunity: twenty years of T cells. Brain Behav Immun. 2007 Oct; 21(7):872-80.
    View in: PubMed
  28. Cao L, Hudson CA, Moynihan JA. Chronic foot shock induces hyperactive behaviors and accompanying pro- and anti-inflammatory responses in mice. J Neuroimmunol. 2007 May; 186(1-2):63-74.
    View in: PubMed
  29. Wyman PA, Moynihan J, Eberly S, Cox C, Cross W, Jin X, Caserta MT. Association of family stress with natural killer cell activity and the frequency of illnesses in children. Arch Pediatr Adolesc Med. 2007 Mar; 161(3):228-34.
    View in: PubMed
  30. Lioy DT, Sheridan PA, Hurley SD, Walton JR, Martin AM, Olschowka JA, Moynihan JA. Acute morphine exposure potentiates the development of HSV-1-induced encephalitis. J Neuroimmunol. 2006 Mar; 172(1-2):9-17.
    View in: PubMed
  31. Sheridan PA, Moynihan JA. Modulation of the innate immune response to HSV-1 following acute administration of morphine: role of hypothalamo-pituitary-adrenal axis. J Neuroimmunol. 2005 Jan; 158(1-2):145-52.
    View in: PubMed
  32. Lyness JM, Moynihan JA, Caine ED. Inflammatory markers, depression, and cardiac disease. Am J Psychiatry. 2005 Jan; 162(1):195; author reply 195.
    View in: PubMed
  33. Cao L, Martin A, Polakos N, Moynihan JA. Stress causes a further decrease in immunity to herpes simplex virus-1 in immunocompromised hosts. J Neuroimmunol. 2004 Nov; 156(1-2):21-30.
    View in: PubMed
  34. Moynihan JA, Larson MR, Treanor J, Duberstein PR, Power A, Shore B, Ader R. Psychosocial factors and the response to influenza vaccination in older adults. Psychosom Med. 2004 Nov-Dec; 66(6):950-3.
    View in: PubMed
  35. Kohut ML, Senchina DS, Madden KS, Martin AE, Felten DL, Moynihan JA. Age effects on macrophage function vary by tissue site, nature of stimulant, and exercise behavior. Exp Gerontol. 2004 Sep; 39(9):1347-60.
    View in: PubMed
  36. Moynihan J, Kruszewska B, Madden K, Callahan T. Sympathetic nervous system regulation of immunity. J Neuroimmunol. 2004 Feb; 147(1-2):87-90.
    View in: PubMed
  37. Kelley SP, Moynihan JA, Stevens SY, Grota LJ, Felten DL. Sympathetic nerve destruction in spleen in murine AIDS. Brain Behav Immun. 2003 Apr; 17(2):94-109.
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  38. Moynihan JA. Mechanisms of stress-induced modulation of immunity. Brain Behav Immun. 2003 Feb; 17 Suppl 1:S11-6.
    View in: PubMed
  39. Rice PA, Boehm GW, Moynihan JA, Bellinger DL, Stevens SY. Chemical sympathectomy increases numbers of inflammatory cells in the peritoneum early in murine listeriosis. Brain Behav Immun. 2002 Dec; 16(6):654-62.
    View in: PubMed
  40. Callahan TA, Moynihan JA. Contrasting pattern of cytokines in antigen- versus mitogen-stimulated splenocyte cultures from chemically denervated mice. Brain Behav Immun. 2002 Dec; 16(6):764-73.
    View in: PubMed
  41. Kelley SP, Moynihan JA, Stevens SY, Grota LJ, Felten DL. Chemical sympathectomy has no effect on the severity of murine AIDS: murine AIDS alone depletes norepinephrine levels in infected spleen. Brain Behav Immun. 2002 Apr; 16(2):118-39.
    View in: PubMed
  42. Callahan TA, Moynihan JA. The effects of chemical sympathectomy on T-cell cytokine responses are not mediated by altered peritoneal exudate cell function or an inflammatory response. Brain Behav Immun. 2002 Feb; 16(1):33-45.
    View in: PubMed
  43. Rice PA, Boehm GW, Moynihan JA, Bellinger DL, Stevens SY. Chemical sympathectomy alters numbers of splenic and peritoneal leukocytes. Brain Behav Immun. 2002 Feb; 16(1):62-73.
    View in: PubMed
  44. Kohut ML, Boehm GW, Moynihan JA. Moderate exercise is associated with enhanced antigen-specific cytokine, but not IgM antibody production in aged mice. Mech Ageing Dev. 2001 Aug; 122(11):1135-50.
    View in: PubMed
  45. Larson MR, Ader R, Moynihan JA. Heart rate, neuroendocrine, and immunological reactivity in response to an acute laboratory stressor. Psychosom Med. 2001 May-Jun; 63(3):493-501.
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  46. Papathanassoglou ED, Moynihan JA, McDermott MP, Ackerman MH. Expression of Fas (CD95) and Fas ligand on peripheral blood mononuclear cells in critical illness and association with multiorgan dysfunction severity and survival. Crit Care Med. 2001 Apr; 29(4):709-18.
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  47. Rice PA, Boehm GW, Moynihan JA, Bellinger DL, Stevens SY. Chemical sympathectomy increases the innate immune response and decreases the specific immune response in the spleen to infection with Listeria monocytogenes. J Neuroimmunol. 2001 Mar 1; 114(1-2):19-27.
    View in: PubMed
  48. Papathanassoglou ED, Moynihan JA, Ackerman MH, Mantzoros CS. Serum leptin levels are higher but are not independently associated with severity or mortality in the multiple organ dysfunction/systemic inflammatory response syndrome: a matched case control and a longitudinal study. Clin Endocrinol (Oxf). 2001 Feb; 54(2):225-33.
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  49. Kohut ML, Boehm GW, Moynihan JA. Prolonged exercise suppresses antigen-specific cytokine response to upper respiratory infection. J Appl Physiol. 2001 Feb; 90(2):678-84.
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  50. Lyness JM, Moynihan JA, Williford DJ, Cox C, Caine ED. Depression, medical illness, and interleukin-1beta in older cardiac patients. Int J Psychiatry Med. 2001; 31(3):305-10.
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  51. Papathanassoglou ED, Moynihan JA, Vermillion DL, McDermott MP, Ackerman MH. Soluble fas levels correlate with multiple organ dysfunction severity, survival and nitrate levels, but not with cellular apoptotic markers in critically ill patients. Shock. 2000 Aug; 14(2):107-12.
    View in: PubMed
  52. Larson MR, Duberstein PR, Talbot NL, Caldwell C, Moynihan JA. A presurgical psychosocial intervention for breast cancer patients. psychological distress and the immune response. J Psychosom Res. 2000 Feb; 48(2):187-94.
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  53. Moynihan JA, Karp JD, Cohen N, Ader R. Immune deviation following stress odor exposure: role of endogenous opioids. J Neuroimmunol. 2000 Jan 24; 102(2):145-53.
    View in: PubMed
  54. Callahan TA, Moynihan JA, Piekut DT. Central nervous system activation following peripheral chemical sympathectomy: implications for neural-immune interactions. Brain Behav Immun. 1998 Sep; 12(3):230-41.
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  55. Kruszewska B, Felten DL, Stevens SY, Moynihan JA. Sympathectomy-induced immune changes are not abrogated by the glucocorticoid receptor blocker RU-486. Brain Behav Immun. 1998 Sep; 12(3):181-200.
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  56. Moynihan JA, Callahan TA, Kelley SP, Campbell LM. Adrenal hormone modulation of type 1 and type 2 cytokine production by spleen cells: dexamethasone and dehydroepiandrosterone suppress interleukin-2, interleukin-4, and interferon-gamma production in vitro. Cell Immunol. 1998 Feb 25; 184(1):58-64.
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  57. Felten SY, Madden KS, Bellinger DL, Kruszewska B, Moynihan JA, Felten DL. The role of the sympathetic nervous system in the modulation of immune responses. Adv Pharmacol. 1998; 42:583-7.
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  58. Moynihan JA, Kruszewska B, Brenner GJ, Cohen N. Neural, endocrine, and immune system interactions. Relevance for health and disease. Adv Exp Med Biol. 1998; 438:541-9.
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  59. Brenner GJ, Moynihan JA. Stressor-induced alterations in immune response and viral clearance following infection with herpes simplex virus-type 1 in BALB/c and C57B1/6 mice. Brain Behav Immun. 1997 Mar; 11(1):9-23.
    View in: PubMed
  60. Karp JD, Moynihan JA, Ader R. Psychosocial influences on immune responses to HSV-1 infection in BALB/c mice. Brain Behav Immun. 1997 Mar; 11(1):47-62.
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  61. Ostberg JR, Dragone LL, Driskell T, Moynihan JA, Phipps R, Barth RK, Frelinger JG. Disregulated expression of CD43 (leukosialin, sialophorin) in the B cell lineage leads to immunodeficiency. J Immunol. 1996 Dec 1; 157(11):4876-84.
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  62. Moynihan JA, Ader R. Psychoneuroimmunology: animal models of disease. Psychosom Med. 1996 Nov-Dec; 58(6):546-58.
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  63. Buske-Kirschbaum A, Grota L, Kirschbaum C, Bienen T, Moynihan J, Ader R, Blair ML, Hellhammer DH, Felten DL. Conditioned increase in peripheral blood mononuclear cell (PBMC) number and corticosterone secretion in the rat. Pharmacol Biochem Behav. 1996 Sep; 55(1):27-32.
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  64. Kruszewska B, Felten SY, Moynihan JA. Alterations in cytokine and antibody production following chemical sympathectomy in two strains of mice. J Immunol. 1995 Nov 15; 155(10):4613-20.
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  65. Cohen N, Moynihan JA, Ader R. Pavlovian conditioning of the immune system. Int Arch Allergy Immunol. 1994 Oct; 105(2):101-6.
    View in: PubMed
  66. Moynihan JA, Karp JD, Cohen N, Cocke R. Alterations in interleukin-4 and antibody production following pheromone exposure: role of glucocorticoids. J Neuroimmunol. 1994 Oct; 54(1-2):51-8.
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  67. Brenner GJ, Cohen N, Moynihan JA. Similar immune response to nonlethal infection with herpes simplex virus-1 in sensitive (BALB/c) and resistant (C57BL/6) strains of mice. Cell Immunol. 1994 Sep; 157(2):510-24.
    View in: PubMed
  68. Karp JD, Cohen N, Moynihan JA. Quantitative differences in interleukin-2 and interleukin-4 production by antigen-stimulated splenocytes from individually- and group-housed mice. Life Sci. 1994; 55(10):789-95.
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  69. Tuttle RS, Moynihan JA, Grota LJ, Cohen N. CO2 anesthesia facilitates a serum antibody response to orally-administered antigens. Life Sci. 1994; 55(11):879-84.
    View in: PubMed
  70. Madden KS, Moynihan JA, Brenner GJ, Felten SY, Felten DL, Livnat S. Sympathetic nervous system modulation of the immune system. III. Alterations in T and B cell proliferation and differentiation in vitro following chemical sympathectomy. J Neuroimmunol. 1994 Jan; 49(1-2):77-87.
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  71. Ader R, Kelly K, Moynihan JA, Grota LJ, Cohen N. Conditioned enhancement of antibody production using antigen as the unconditioned stimulus. Brain Behav Immun. 1993 Dec; 7(4):334-43.
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  72. Karp JD, Moynihan JA, Ader R. Effects of differential housing on the primary and secondary antibody responses of male C57BL/6 and BALB/c mice. Brain Behav Immun. 1993 Dec; 7(4):326-33.
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  73. Breneman SM, Moynihan JA, Grota LJ, Felten DL, Felten SY. Splenic norepinephrine is decreased in MRL-lpr/lpr mice. Brain Behav Immun. 1993 Jun; 7(2):135-43.
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  74. Cocke R, Moynihan JA, Cohen N, Grota LJ, Ader R. Exposure to conspecific alarm chemosignals alters immune responses in BALB/c mice. Brain Behav Immun. 1993 Mar; 7(1):36-46.
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  75. Kusnecov AV, Grota LJ, Schmidt SG, Bonneau RH, Sheridan JF, Glaser R, Moynihan JA. Decreased herpes simplex viral immunity and enhanced pathogenesis following stressor administration in mice. J Neuroimmunol. 1992 May; 38(1-2):129-37.
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  76. Kusnecov AW, Cohen N, Moynihan J. Adjuvant effects of freely ingested cholera toxin on systemic antibody and DTH responses to protein antigen. Reg Immunol. 1992 May-Jun; 4(3):153-61.
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  77. Moynihan JA, Brenner GJ, Ader R, Cohen N. The effects of handling adult mice on immunologically relevant processes. Ann N Y Acad Sci. 1992 Apr 15; 650:262-7.
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  78. Brenner GJ, Felten SY, Felten DL, Moynihan JA. Sympathetic nervous system modulation of tumor metastases and host defense mechanisms. J Neuroimmunol. 1992 Apr; 37(3):191-201.
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  79. Schiffer RB, Sunderman FW, Baggs RB, Moynihan JA. The effects of exposure to dietary nickel and zinc upon humoral and cellular immunity in SJL mice. J Neuroimmunol. 1991 Nov; 34(2-3):229-39.
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  80. Haynes L, Moynihan JA, Cohen N. A monoclonal antibody against the human IL-2 receptor binds to paraformaldehyde-fixed but not viable frog (Xenopus) splenocytes. Immunol Lett. 1990 Dec; 26(3):227-32.
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  81. Grota LJ, Ader R, Moynihan JA, Cohen N. Voluntary consumption of cyclophosphamide by nondeprived Mrl-lpr/lpr and Mrl +/+ mice. Pharmacol Biochem Behav. 1990 Nov; 37(3):527-30.
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  82. Moynihan JA, Ader R, Grota LJ, Schachtman TR, Cohen N. The effects of stress on the development of immunological memory following low-dose antigen priming in mice. Brain Behav Immun. 1990 Mar; 4(1):1-12.
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  83. Brenner GJ, Cohen N, Ader R, Moynihan JA. Increased pulmonary metastases and natural killer cell activity in mice following handling. Life Sci. 1990; 47(20):1813-9.
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  84. Moynihan J, Brenner G, Koota D, Breneman S, Conen N, Ader R. The effects of handling on antibody production, mitogen responses, spleen cell number, and lymphocyte subpopulations. Life Sci. 1990; 46(26):1937-44.
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  85. Moynihan J, Burstyn D, Zauderer M. Autoreactive T-cell response to resting or activated B cells. Immunology. 1989 Oct; 68(2):199-203.
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  86. Grota LJ, Schachtman TR, Moynihan JA, Cohen N, Ader R. Voluntary consumption of cyclophosphamide by Mrl mice. Brain Behav Immun. 1989 Sep; 3(3):263-73.
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  87. Moynihan J, Koota D, Brenner G, Cohen N, Ader R. Repeated intraperitoneal injections of saline attenuate the antibody response to a subsequent intraperitoneal injection of antigen. Brain Behav Immun. 1989 Mar; 3(1):90-6.
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  88. Moynihan J, Cohen N. The kinetics of recovery of leukocyte number and lymphocyte function following an injection of a single high dose of cyclophosphamide in C3H/HeJ mice. Int J Immunopharmacol. 1989; 11(5):517-27.
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  89. Moynihan JA, Looney RJ, Abraham GN. The V kappa IIIb light chain sub-subgroup. II. Isotype expression in acquired hypogammaglobulinaemia and as a function of age. Immunology. 1986 Feb; 57(2):325-7.
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  90. Moynihan JA, Looney RJ, Abraham GN. The VKIIIb light chain sub-subgroup: restricted association with mu heavy chain in normal human serum. Immunology. 1985 Feb; 54(2):207-13.
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