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Richard Barth

TitleAssociate Professor (Part-Time)
InstitutionSchool of Medicine and Dentistry
DepartmentMicrobiology and Immunology
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 672
Rochester NY 14642
 
 Selected Publications
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  1. Wagner VE, Frelinger JG, Barth RK, Iglewski BH. Quorum sensing: dynamic response of Pseudomonas aeruginosa to external signals. Trends Microbiol. 2006 Feb; 14(2):55-8.
    View in: PubMed
  2. Thatcher TH, Sime PJ, Barth RK. Sensitivity to bleomycin-induced lung injury is not moderated by an antigen-limited T-cell repertoire. Exp Lung Res. 2005 Sep; 31(7):685-700.
    View in: PubMed
  3. Burns R, Luzina I, Nasir A, Haidaris CG, Barth RK, Gaspari AA. Keratinocyte-derived, CD80-mediated costimulation is associated with hapten-specific IgE production during contact hypersensitivity to TH1 haptens. J Allergy Clin Immunol. 2005 Feb; 115(2):383-90.
    View in: PubMed
  4. Kuzin II, Ugine GD, Barth RK, Shultz LD, Nahm MH, Young FM, Bottaro A. A new murine model of humoral immuno-deficiency specifically affects class switching to T-independent antigens. Eur J Immunol. 2004 Jul; 34(7):1807-16.
    View in: PubMed
  5. Barth RK, Hanchett LA, Baecher-Allan CM. Mapping susceptibility genes for the induction of pulmonary fibrosis in mice. Chest. 2002 Mar; 121(3 Suppl):21S.
    View in: PubMed
  6. Thatcher TH, O'Brien DP, Altuwaijri S, Barth RK. Increasing the frequency of T-cell precursors specific for a cryptic epitope of hen-egg lysozyme converts it to an immunodominant epitope. Immunology. 2000 Feb; 99(2):235-42.
    View in: PubMed
  7. Burns RP, Nasir A, Haake AR, Barth RK, Gaspari AA. B7-1 overexpression by thymic epithelial cells results in transient and long-lasting effects on thymocytes and peripheral T helper cells but does not result in immunodeficiency. Cell Immunol. 1999 Jun 15; 194(2):162-77.
    View in: PubMed
  8. Ostberg JR, Barth RK, Frelinger JG. The Roman god Janus: a paradigm for the function of CD43. Immunol Today. 1998 Dec; 19(12):546-50.
    View in: PubMed
  9. Wei C, Callahan BP, Turner MJ, Willis RA, Lord EM, Barth RK, Frelinger JG. Regulation of human prostate-specific antigen gene expression in transgenic mice: evidence for an enhancer between the PSA and human glandular kallikrein-1 genes. Int J Mol Med. 1998 Oct; 2(4):487-96.
    View in: PubMed
  10. Gaspari AA, Burns R, Nasir A, Ramirez D, Barth RK, Haidaris CG. CD86 (B7-2), but not CD80 (B7-1), expression in the epidermis of transgenic mice enhances the immunogenicity of primary cutaneous Candida albicans infections. Infect Immun. 1998 Sep; 66(9):4440-9.
    View in: PubMed
  11. Daly HE, Baecher-Allan CM, Paxhia AT, Ryan RM, Barth RK, Finkelstein JN. Cell-specific gene expression reveals changes in epithelial cell populations after bleomycin treatment. Lab Invest. 1998 Apr; 78(4):393-400.
    View in: PubMed
  12. Gaspari AA, Burns RP, Kondo S, Nasir A, Kurup A, Mlodynia D, Sauder D, Barth RK. Characterization of the altered cutaneous reactivity of transgenic mice whose keratinocytes overexpress B7-1. Clin Immunol Immunopathol. 1998 Mar; 86(3):259-70.
    View in: PubMed
  13. Willis RA, Wei C, Turner MJ, Callahan BP, Pugh AE, Barth RK, Lord EM, Frelinger JG. A transgenic strategy for analyzing the regulatory regions of the human prostate-specific antigen gene: potential applications for the treatment of prostate cancer (Review). Int J Mol Med. 1998 Feb; 1(2):379-86.
    View in: PubMed
  14. Burns RP, Natarajan K, LoCascio NJ, O'Brien DP, Kobori JA, Shastri N, Barth RK. Molecular analysis of skewed Tcra-V gene use in T-cell receptor beta-chain transgenic mice. Immunogenetics. 1998; 47(2):107-14.
    View in: PubMed
  15. Ostberg JR, Dragone LL, Borrello MA, Phipps RP, Barth RK, Frelinger JG. Expression of mouse CD43 in the B cell lineage of transgenic mice causes impaired immune responses to T-independent antigens. Eur J Immunol. 1997 Sep; 27(9):2152-9.
    View in: PubMed
  16. O'Brien DP, Baecher-Allan CM, Burns RP, Shastri N, Barth RK. Elimination of T-cell-receptor beta-chain diversity in transgenic mice restricts antigen-specific but not alloreactive responses. Immunology. 1997 Jul; 91(3):375-82.
    View in: PubMed
  17. Wei C, Willis RA, Tilton BR, Looney RJ, Lord EM, Barth RK, Frelinger JG. Tissue-specific expression of the human prostate-specific antigen gene in transgenic mice: implications for tolerance and immunotherapy. Proc Natl Acad Sci U S A. 1997 Jun 10; 94(12):6369-74.
    View in: PubMed
  18. Zambidis ET, Barth RK, Scott DW. Both resting and activated B lymphocytes expressing engineered peptide-Ig molecules serve as highly efficient tolerogenic vehicles in immunocompetent adult recipients. J Immunol. 1997 Mar 1; 158(5):2174-82.
    View in: PubMed
  19. Daly HE, Baecher-Allan CM, Barth RK, D'Angio CT, Finkelstein JN. Bleomycin induces strain-dependent alterations in the pattern of epithelial cell-specific marker expression in mouse lung. Toxicol Appl Pharmacol. 1997 Feb; 142(2):303-10.
    View in: PubMed
  20. Ostberg JR, Dragone LL, Driskell T, Moynihan JA, Phipps R, Barth RK, Frelinger JG. Disregulated expression of CD43 (leukosialin, sialophorin) in the B cell lineage leads to immunodeficiency. J Immunol. 1996 Dec 1; 157(11):4876-84.
    View in: PubMed
  21. Wei C, Storozynsky E, McAdam AJ, Yeh KY, Tilton BR, Willis RA, Barth RK, Looney RJ, Lord EM, Frelinger JG. Expression of human prostate-specific antigen (PSA) in a mouse tumor cell line reduces tumorigenicity and elicits PSA-specific cytotoxic T lymphocytes. Cancer Immunol Immunother. 1996 Jul; 42(6):362-8.
    View in: PubMed
  22. Sempowski GD, Borrello MA, Blieden TM, Barth RK, Phipps RP. Fibroblast heterogeneity in the healing wound. Wound Repair Regen. 1995 Apr-Jun; 3(2):120-31.
    View in: PubMed
  23. Dragone LL, Barth RK, Sitar KL, Disbrow GL, Frelinger JG. Disregulation of leukosialin (CD43, Ly48, sialophorin) expression in the B-cell lineage of transgenic mice increases splenic B-cell number and survival. Proc Natl Acad Sci U S A. 1995 Jan 17; 92(2):626-30.
    View in: PubMed
  24. Nasir A, Ferbel B, Salminen W, Barth RK, Gaspari AA. Exaggerated and persistent cutaneous delayed-type hypersensitivity in transgenic mice whose epidermal keratinocytes constitutively express B7-1 antigen. J Clin Invest. 1994 Aug; 94(2):892-8.
    View in: PubMed
  25. Baecher-Allan CM, Barth RK. PCR analysis of cytokine induction profiles associated with mouse strain variation in susceptibility to pulmonary fibrosis. Reg Immunol. 1993 May-Aug; 5(3-4):207-17.
    View in: PubMed
  26. Baecher-Allan CM, Kemp JD, Dorfman KS, Barth RK, Frelinger JG. Differential epitope expression of Ly-48 (mouse leukosialin). Immunogenetics. 1993; 37(3):183-92.
    View in: PubMed
  27. Klotz JL, Barth RK, Kiser GL, Hood LE, Kronenberg M. Restriction fragment length polymorphisms of the mouse T-cell receptor gene families. Immunogenetics. 1989; 29(3):191-201.
    View in: PubMed
  28. Wilson RK, Lai E, Concannon P, Barth RK, Hood LE. Structure, organization and polymorphism of murine and human T-cell receptor alpha and beta chain gene families. Immunol Rev. 1988 Jan; 101:149-72.
    View in: PubMed
  29. Lai E, Barth RK, Hood L. Genomic organization of the mouse T-cell receptor beta-chain gene family. Proc Natl Acad Sci U S A. 1987 Jun; 84(11):3846-50.
    View in: PubMed
  30. Barth RK, Kim BS, Lan NC, Hunkapiller T, Sobieck N, Winoto A, Gershenfeld H, Okada C, Hansburg D, Weissman IL, et al. The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments. Nature. 1985 Aug 8-14; 316(6028):517-23.
    View in: PubMed
  31. Hill RE, Shaw PH, Barth RK, Hastie ND. A genetic locus closely linked to a protease inhibitor gene complex controls the level of multiple RNA transcripts. Mol Cell Biol. 1985 Aug; 5(8):2114-22.
    View in: PubMed
  32. Graves DT, Owen AJ, Barth RK, Tempst P, Winoto A, Fors L, Hood LE, Antoniades HN. Detection of c-sis transcripts and synthesis of PDGF-like proteins by human osteosarcoma cells. Science. 1984 Nov 23; 226(4677):972-4.
    View in: PubMed
  33. Bennett KL, Lalley PA, Barth RK, Hastie ND. Mapping the structural genes coding for the major urinary proteins in the mouse: combined use of recombinant inbred strains and somatic cell hybrids. Proc Natl Acad Sci U S A. 1982 Feb; 79(4):1220-4.
    View in: PubMed
  34. Barth RK, Gross KW, Gremke LC, Hastie ND. Developmentally regulated mRNAs in mouse liver. Proc Natl Acad Sci U S A. 1982 Jan; 79(2):500-4.
    View in: PubMed

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