Ellen Henry
| Title | Research Assistant Prof (Part-Time) |
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| Institution | School of Medicine and Dentistry |
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| Department | Environmental Medicine |
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| Address | University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box EHSC
Rochester NY 14642
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Latchney SE, Lioy DT, Henry EC, Gasiewicz TA, Strathmann FG, Mayer-Pröschel M, Opanashuk LA. Neural precursor cell proliferation is disrupted through activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Stem Cells Dev. 2011 Feb; 20(2):313-26.
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Henry EC, Welle SL, Gasiewicz TA. TCDD and a putative endogenous AhR ligand, ITE, elicit the same immediate changes in gene expression in mouse lung fibroblasts. Toxicol Sci. 2010 Mar; 114(1):90-100.
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Yin Z, Henry EC, Gasiewicz TA. (-)-Epigallocatechin-3-gallate is a novel Hsp90 inhibitor. Biochemistry. 2009 Jan 20; 48(2):336-45.
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Henry EC, Gasiewicz TA. Molecular determinants of species-specific agonist and antagonist activity of a substituted flavone towards the aryl hydrocarbon receptor. Arch Biochem Biophys. 2008 Apr 15; 472(2):77-88.
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Gasiewicz TA, Henry EC, Collins LL. Expression and activity of aryl hydrocarbon receptors in development and cancer. Crit Rev Eukaryot Gene Expr. 2008; 18(4):279-321.
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Kim SH, Henry EC, Kim DK, Kim YH, Shin KJ, Han MS, Lee TG, Kang JK, Gasiewicz TA, Ryu SH, Suh PG. Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor. Mol Pharmacol. 2006 Jun; 69(6):1871-8.
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Henry EC, Bemis JC, Henry O, Kende AS, Gasiewicz TA. A potential endogenous ligand for the aryl hydrocarbon receptor has potent agonist activity in vitro and in vivo. Arch Biochem Biophys. 2006 Jun 1; 450(1):67-77.
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Zhou JG, Henry EC, Palermo CM, Dertinger SD, Gasiewicz TA. Species-specific transcriptional activity of synthetic flavonoids in guinea pig and mouse cells as a result of differential activation of the aryl hydrocarbon receptor to interact with dioxin-responsive elements. Mol Pharmacol. 2003 Apr; 63(4):915-24.
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Henry EC, Gasiewicz TA. Agonist but not antagonist ligands induce conformational change in the mouse aryl hydrocarbon receptor as detected by partial proteolysis. Mol Pharmacol. 2003 Feb; 63(2):392-400.
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Park S, Henry EC, Gasiewicz TA. Regulation of DNA binding activity of the ligand-activated aryl hydrocarbon receptor by tyrosine phosphorylation. Arch Biochem Biophys. 2000 Sep 15; 381(2):302-12.
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Henry EC, Kende AS, Rucci G, Totleben MJ, Willey JJ, Dertinger SD, Pollenz RS, Jones JP, Gasiewicz TA. Flavone antagonists bind competitively with 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD) to the aryl hydrocarbon receptor but inhibit nuclear uptake and transformation. Mol Pharmacol. 1999 Apr; 55(4):716-25.
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Henry EC, Kent TA, Gasiewicz TA. DNA binding and transcriptional enhancement by purified TCDD.Ah receptor complex. Arch Biochem Biophys. 1997 Mar 15; 339(2):305-14.
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Germolec DR, Henry EC, Maronpot R, Foley JF, Adams NH, Gasiewicz TA, Luster MI. Induction of CYP1A1 and ALDH-3 in lymphoid tissues from Fisher 344 rats exposed to 2,3,7,8-tetrachlorodibenzodioxin (TCDD). Toxicol Appl Pharmacol. 1996 Mar; 137(1):57-66.
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Henry EC, Rucci G, Gasiewicz TA. Purification to homogeneity of the heteromeric DNA-binding form of the aryl hydrocarbon receptor from rat liver. Mol Pharmacol. 1994 Dec; 46(6):1022-7.
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Henry EC, Gasiewicz TA. Transformation of the aryl hydrocarbon receptor to a DNA-binding form is accompanied by release of the 90 kDa heat-shock protein and increased affinity for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochem J. 1993 Aug 15; 294 ( Pt 1):95-101.
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Henry EC, Hayden KA, Bauman PA, Gasiewicz TA. Ribonuclease inhibits Ah receptor transformation in vitro. Biochem J. 1991 Nov 1; 279 ( Pt 3):689-94.
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Henry EC, Gasiewicz TA. Inhibition and reconstitution of Ah receptor transformation in vitro: role and partial characterization of a cytosolic factor(s). Arch Biochem Biophys. 1991 Jul; 288(1):149-56.
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Gasiewicz TA, Elferink CJ, Henry EC. Characterization of multiple forms of the Ah receptor: recognition of a dioxin-responsive enhancer involves heteromer formation. Biochemistry. 1991 Mar 19; 30(11):2909-16.
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Henry EC, Rucci G, Gasiewicz TA. Characterization of multiple forms of the Ah receptor: comparison of species and tissues. Biochemistry. 1989 Jul 25; 28(15):6430-40.
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Henry EC, Kester JE, Gasiewicz TA. Effects of SH-modifying reagents on the rat hepatic Ah receptor: inhibition of ligand binding and transformation, and disruption of the ligand-receptor complex. Biochim Biophys Acta. 1988 Mar 17; 964(3):361-76.
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Henry EC, Gasiewicz TA. Changes in thyroid hormones and thyroxine glucuronidation in hamsters compared with rats following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol. 1987 Jun 30; 89(2):165-74.
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Gasiewicz TA, Rucci G, Henry EC, Baggs RB. Changes in hamster hepatic cytochrome P-450, ethoxycoumarin O-deethylase, and reduced NAD(P): menadione oxidoreductase following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Partial dissociation of temporal and dose-response relationships from elicited toxicity. Biochem Pharmacol. 1986 Aug 15; 35(16):2737-42.
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Henry EC, Miller RK. The antiestrogen LY117018 is estrogenic in the fetal rat. Teratology. 1986 Aug; 34(1):59-63.
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Huang Lu CJ, Baggs RB, Redmond D, Henry EC, Schecter A, Gasiewicz TA. Toxicity and evidence for metabolic alterations in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated guinea pigs fed by total parenteral nutrition. Toxicol Appl Pharmacol. 1986 Jul; 84(3):439-53.
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Henry EC, Miller RK. Comparison of the disposition of diethylstilbestrol and estradiol in the fetal rat. Correlation with teratogenic potency. Biochem Pharmacol. 1986 Jun 15; 35(12):1993-2001.
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Henry EC, Miller RK, Baggs RB. Direct fetal injections of diethylstilbestrol and 17 beta-estradiol: a method for investigating their teratogenicity. Teratology. 1984 Apr; 29(2):297-304.
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