URMC Research Network - Michael Elliott

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Michael Elliott

Title	Assistant Professor
Institution	School of Medicine and Dentistry
Department	Microbiology and Immunology in the Center for Vaccine Biology and Immunology
Address	University of Rochester Medical Center School of Medicine and Dentistry 601 Elmwood Ave, Box 609 Rochester NY 14642

Awards And Honors

2006	-	2009	Postdoctoral Fellowship \| American Cancer Society
2008			Farrow Fellowship \| University of Virginia Cancer Center
2010			Outstanding Trainee Investigator Award \| American Society of Andrology
2010			Thomas S. K. Chang Travel Award \| American Society of Andrology
2011			New Scholar in Aging \| Ellison Medical Foundation
2012	-	2014	Creative and Novel Ideas in HIV Research Award \| Center for AIDS Research / NIH

Selected Publications

Park D, Han CZ, Elliott MR, Kinchen JM, Trampont PC, Das S, Collins S, Lysiak JJ, Hoehn KL, Ravichandran KS. Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein. Nature. 2011 Sep 8; 477(7363):220-4.

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Lu Z, Elliott MR, Chen Y, Walsh JT, Klibanov AL, Ravichandran KS, Kipnis J. Phagocytic activity of neuronal progenitors regulates adult neurogenesis. Nat Cell Biol. 2011 Sep; 13(9):1076-83.

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Rao J, Elliott MR, Leitinger N, Jensen RV, Goldberg JB, Amin AR. RahU: an inducible and functionally pleiotropic protein in Pseudomonas aeruginosa modulates innate immunity and inflammation in host cells. Cell Immunol. 2011; 270(2):103-13.

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Chekeni FB, Elliott MR, Sandilos JK, Walk SF, Kinchen JM, Lazarowski ER, Armstrong AJ, Penuela S, Laird DW, Salvesen GS, Isakson BE, Bayliss DA, Ravichandran KS. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature. 2010 Oct 14; 467(7317):863-7.

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Elliott MR, Ravichandran KS. ELMO1 signaling in apoptotic germ cell clearance and spermatogenesis. Ann N Y Acad Sci. 2010 Oct; 1209:30-6.

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Elliott MR, Zheng S, Park D, Woodson RI, Reardon MA, Juncadella IJ, Kinchen JM, Zhang J, Lysiak JJ, Ravichandran KS. Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo. Nature. 2010 Sep 16; 467(7313):333-7.

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Kadl A, Meher AK, Sharma PR, Lee MY, Doran AC, Johnstone SR, Elliott MR, Gruber F, Han J, Chen W, Kensler T, Ravichandran KS, Isakson BE, Wamhoff BR, Leitinger N. Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2. Circ Res. 2010 Sep 17; 107(6):737-46.

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Elliott MR, Ravichandran KS. Clearance of apoptotic cells: implications in health and disease. J Cell Biol. 2010 Jun 28; 189(7):1059-70.

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Elliott MR, Chekeni FB, Trampont PC, Lazarowski ER, Kadl A, Walk SF, Park D, Woodson RI, Ostankovich M, Sharma P, Lysiak JJ, Harden TK, Leitinger N, Ravichandran KS. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature. 2009 Sep 10; 461(7261):282-6.

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Elliott MR, Ravichandran KS. Death in the CNS: six-microns-under. Cell. 2008 May 2; 133(3):393-5.

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Elliott MR, Ravichandran KS. Pallbearer and friends: lending a hand in apoptotic cell clearance. Trends Cell Biol. 2008 Mar; 18(3):95-7.

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Park D, Tosello-Trampont AC, Elliott MR, Lu M, Haney LB, Ma Z, Klibanov AL, Mandell JW, Ravichandran KS. BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module. Nature. 2007 Nov 15; 450(7168):430-4.

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Kiss RS, Elliott MR, Ma Z, Marcel YL, Ravichandran KS. Apoptotic cells induce a phosphatidylserine-dependent homeostatic response from phagocytes. Curr Biol. 2006 Nov 21; 16(22):2252-8.

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Elliott MR, Shanks RA, Khan IU, Brooks JW, Burkett PJ, Nelson BJ, Kyttaris V, Juang YT, Tsokos GC, Kammer GM. Down-regulation of IL-2 production in T lymphocytes by phosphorylated protein kinase A-RIIbeta. J Immunol. 2004 Jun 15; 172(12):7804-12.

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