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Jennifer Jonason

TitleResearch Assistant Professor
InstitutionSchool of Medicine and Dentistry
DepartmentOrthopaedics in the Center for Musculoskeletal Research
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 665
Rochester NY 14642
 
 Selected Publications
  • Dao DY, Jonason JH, Zhang Y, Hsu W, Chen D, Hilton MJ, O'Keefe RJ. Cartilage-specific ß-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development. J Bone Miner Res. 2012 Aug; 27(8):1680-94.
    View in: PubMed
  • Metz-Estrella D, Jonason JH, Sheu TJ, Mroczek-Johnston RM, Puzas JE. TRIP-1: A regulator of osteoblast function. J Bone Miner Res. 2012 Jul; 27(7):1576-84.
    View in: PubMed
  • Zhang M, Ho HC, Sheu TJ, Breyer MD, Flick LM, Jonason JH, Awad HA, Schwarz EM, O'Keefe RJ. EP1(-/-) mice have enhanced osteoblast differentiation and accelerated fracture repair. J Bone Miner Res. 2011 Apr; 26(4):792-802.
    View in: PubMed
  • Gunnell LM, Jonason JH, Loiselle AE, Kohn A, Schwarz EM, Hilton MJ, O'Keefe RJ. TAK1 regulates cartilage and joint development via the MAPK and BMP signaling pathways. J Bone Miner Res. 2010 Aug; 25(8):1784-97.
    View in: PubMed
  • Li TF, Gao L, Sheu TJ, Sampson ER, Flick LM, Konttinen YT, Chen D, Schwarz EM, Zuscik MJ, Jonason JH, O'Keefe RJ. Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis. Arthritis Rheum. 2010 Aug; 62(8):2359-69.
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  • Yan Y, Tang D, Chen M, Huang J, Xie R, Jonason JH, Tan X, Hou W, Reynolds D, Hsu W, Harris SE, Puzas JE, Awad H, O'Keefe RJ, Boyce BF, Chen D. Axin2 controls bone remodeling through the beta-catenin-BMP signaling pathway in adult mice. J Cell Sci. 2009 Oct 1; 122(Pt 19):3566-78.
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  • Jonason JH, Xiao G, Zhang M, Xing L, Chen D. Post-translational Regulation of Runx2 in Bone and Cartilage. J Dent Res. 2009 Aug; 88(8):693-703.
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  • Zhang M, Xie R, Hou W, Wang B, Shen R, Wang X, Wang Q, Zhu T, Jonason JH, Chen D. PTHrP prevents chondrocyte premature hypertrophy by inducing cyclin-D1-dependent Runx2 and Runx3 phosphorylation, ubiquitylation and proteasomal degradation. J Cell Sci. 2009 May 1; 122(Pt 9):1382-9.
    View in: PubMed
  • Jonason JH, Gavrilova N, Wu M, Zhang H, Sun H. Regulation of SCF(SKP2) ubiquitin E3 ligase assembly and p27(KIP1) proteolysis by the PTEN pathway and cyclin D1. Cell Cycle. 2007 Apr 15; 6(8):951-61.
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  • Nissbrandt H, Bergquist F, Jonason J, Engberg G. Inhibition of cytochrome P450 2E1 induces an increase in extracellular dopamine in rat substantia nigra: a new metabolic pathway? Synapse. 2001 Jun 15; 40(4):294-301.
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  • Bergquist F, Jonason J, Pileblad E, Nissbrandt H. Effects of local administration of L-, N-, and P/Q-type calcium channel blockers on spontaneous dopamine release in the striatum and the substantia nigra: a microdialysis study in rat. J Neurochem. 1998 Apr; 70(4):1532-40.
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  • Elverfors A, Pileblad E, Lagerkvist S, Bergquist F, Jonason J, Nissbrandt H. 3-Methoxytyramine formation following monoamine oxidase inhibition is a poor index of dendritic dopamine release in the substantia nigra. J Neurochem. 1997 Oct; 69(4):1684-92.
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  • Elverfors A, Jonason J, Jonason G, Nissbrandt H. Effects of drugs interfering with sodium channels and calcium channels on the release of endogenous dopamine from superfused substantia nigra slices. Synapse. 1997 Aug; 26(4):359-69.
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  • Engberg G, Elverfors A, Jonason J, Nissbrandt H. Inhibition of dopamine re-uptake: significance for nigral dopamine neuron activity. Synapse. 1997 Feb; 25(2):215-26.
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  • Elverfors A, Jonason J, Jonason G, Leonsson G, Nissbrandt H. Determination of release of endogenous dopamine from superfused substantia nigra slices. J Neurosci Methods. 1992 Dec; 45(3):209-15.
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  • Hedner J, McCown TJ, Mueller RA, Hedner T, Jonason J, Breese GR. Respiratory stimulant effects by TRH into the mesencephalic region in the rat. Acta Physiol Scand. 1987 May; 130(1):69-75.
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  • Hedner J, Hedner T, Jonason J. Capsaicin and regulation of respiration: interaction with central substance P mechanisms. J Neural Transm. 1985; 61(3-4):239-52.
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  • Hedner T, Hedner J, Bergman B, Mueller RA, Jonason J. Characterization of adenosine-induced respiratory depression in the preterm rabbit. Biol Neonate. 1985; 47(6):323-32.
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  • Wessberg P, Hedner J, Hedner T, Persson B, Jonason J. Adenosine mechanisms in the regulation of breathing in the rat. Eur J Pharmacol. 1984 Oct 30; 106(1):59-67.
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  • Hedner J, Hedner T, Wessberg P, Jonason J. An analysis of the mechanism by which gamma-aminobutyric acid depresses ventilation in the rat. J Appl Physiol. 1984 Apr; 56(4):849-56.
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  • Hedner T, Hedner J, Jonason J, Wessberg P. Effects of theophylline on adenosine-induced respiratory depression in the preterm rabbit. Eur J Respir Dis. 1984 Feb; 65(2):153-6.
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  • Hedner J, Hedner T, Wessberg P, Jonason J. Interaction of substance P with the respiratory control system in the rat. J Pharmacol Exp Ther. 1984 Jan; 228(1):196-201.
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  • Wessberg P, Hedner T, Hedner J, Jonason J. Effects of taurine and a taurine antagonist on some respiratory and cardiovascular parameters. Life Sci. 1983 Oct 24; 33(17):1649-55.
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  • Wessberg P, Hedner J, Hedner T, Jonason J. Central respiratory and cardiovascular effects in the rat of some putative neurotransmitter amino acids. Naunyn Schmiedebergs Arch Pharmacol. 1983 Jun; 323(1):58-65.
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  • Hedner J, Hedner T, Wessberg P, Lundberg D, Jonason J. Effects of TRH and TRH analogues on the central regulation of breathing in the rat. Acta Physiol Scand. 1983 Mar; 117(3):427-37.
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  • Hedner T, Hedner J, Bergman B, Iversen K, Jonason J. Effects of GABA and some GABA analogues on respiratory regulation in the preterm rabbit. Biol Neonate. 1983; 43(3-4):134-45.
    View in: PubMed
  • Hedner T, Hedner J, Wessberg P, Jonason J. Regulation of breathing in the rat: indications for a role of central adenosine mechanisms. Neurosci Lett. 1982 Nov 30; 33(2):147-51.
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  • Mueller RA, Lundberg DB, Breese GR, Hedner J, Hedner T, Jonason J. The neuropharmacology of respiratory control. Pharmacol Rev. 1982 Sep; 34(3):255-85.
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  • Hedner J, Hedner T, Jonason J, Lundberg D. Evidence for a dopamine interaction with the central respiratory control system in the rat. Eur J Pharmacol. 1982 Jul 30; 81(4):603-15.
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  • Hedner T, Hedner J, Jonason J, Lundberg D. Respiratory effects of TRH in preterm rabbits. Pediatr Res. 1982 Jul; 16(7):543-8.
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  • Hedner J, Hedner T, Jonason J, Lundberg D. Central respiratory stimulant effect by thyrotropin in releasing hormone in the rat. Neurosci Lett. 1981 Sep 25; 25(3):317-20.
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  • Hedner T, Hedner J, Jonason J, Lundberg D. Evidence suggesting a role for substance P in central respiratory regulation in the rat. Acta Physiol Scand. 1981 Aug; 112(4):487-9.
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  • Hedner J, Almgren O, Jonason J, Lundberg D. Neuronal and extraneuronal uptake of 3H-noradrenaline in rat portal vein in vitro. Acta Physiol Scand. 1981 Feb; 111(2):171-7.
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  • Hallberg H, Almgren O, Engel J, Jonason J. Effects of propranolol on the locomotor stimulation induced by activation of postsynaptic catecholamine receptors. Psychopharmacology (Berl). 1981; 72(3):227-31.
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  • Hedner J, Hedner T, Jonason J, Lundberg D. GABA-ergic mechanisms in central respiratory control in the anesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1981; 317(4):315-20.
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  • Hedner J, Jonason J, Lundberg D. Respiratory effects of gamma-hydroxybutyric acid in anesthetized rats. J Neural Transm. 1980; 49(3):179-86.
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  • Almgren O, Jonason J. Functional significance of neuronal and extraneuronal transmitter uptake in rat salivary glands. The effect of protriptyline and normetanephrine. Naunyn Schmiedebergs Arch Pharmacol. 1974; 283(1):1-20.
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  • Almgren O, Jonason J. On the role of the adrenergic receptors for extraneuronal amine uptake and retention in rat salivary glands in vitro. Naunyn Schmiedebergs Arch Pharmacol. 1974; 283(1):21-35.
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  • Almgren O, Jonason J. The effect of corticosterone on extraneuronal amine uptake and effector response in rat salivary glands. J Pharm Pharmacol. 1973 Jul; 25(7):537-43.
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  • Häggendal J, Johansson B, Jonason J, Ljung B. Effects of a bicyclic thymoleptic drug (LU 3-010) on neuroeffector function in rat isolated portal veins. J Pharm Pharmacol. 1972 Jul; 24(7):557-64.
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  • Häggendal J, Johansson B, Jonason J, Ljung B. Effects of phenoxybenzamine on transmitter release and effector response in the isolated portal vein. J Pharm Pharmacol. 1972 Feb; 24(2):161-4.
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  • Almgren O, Jonason J. The effect of protriptyline on uptake and retention of dl-3H-noradrenaline in different tissues of the rat. Acta Physiol Scand. 1971 Jun; 82(2):282-8.
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  • Almgren O, Jonason J. Relative importance of neuronal and extraneuronal mechanisms for the uptake and retention of noradrenaline in different tissues of the rat. Naunyn Schmiedebergs Arch Pharmakol. 1971; 270(3):289-309.
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  • Jonason J. Prevention of the reserpine effect on rat salivary gland noradrenaline by inhibitors of monoamine oxidase and catechol-O-methyl transferase. J Pharm Pharmacol. 1970 Feb; 22(2):93-5.
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  • Häggendal J, Johansson B, Jonason J, Ljung B. Correlation between noradrenaline release and effector response to nerve stimulation in rat portal vein in vitro. Acta Physiol Scand Suppl. 1970; 349:17-32.
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  • Jonason J. The accumulation of Dopa-decarboxylase and MAO activity in rat sciatic nerves after constriction. Acta Physiol Scand Suppl. 1970; 357:11.
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  • Carlsson A, Jonason J, Lindqvist M. On the mechanism of 5-hydroxytryptamine release by thymoleptics. J Pharm Pharmacol. 1969 Nov; 21(11):769-73.
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  • Jonason J. Metabolism of dopamine and noradrenaline in normal, atrophied and postganglionically sympathectomized rat salivary glands in vitro. Acta Physiol Scand. 1969 Jul; 76(3):299-311.
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  • Jonason J, Rutledge CO. Effects of reserpine, dopamine and nialamide on the synthesis of alpha-methylnoradrenaline. Eur J Pharmacol. 1969 Apr; 6(1):24-8.
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  • Carlsson A, Jonason J, Lindqvist M, Fuxe K. Demonstration of extraneuronal 5-hydroxytryptamine accumulation in brain following membrane-pump blockade by chlorimipramine. Brain Res. 1969 Feb; 12(2):456-60.
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  • Dahlström A, Jonason J, Norberg KA. Monoamine oxidase activity in rat sciatic nerves after constriction. Eur J Pharmacol. 1969; 6(3):248-54.
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  • Jonason J. The effect of protriptyline on dopamine and noradrenaline metabolism in normal and atrophied rat salivary glands in vitro. Acta Pharmacol Toxicol (Copenh). 1969; 27(1):60-72.
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  • Jonason J. Activities of monoamine metabolizing enzymes in rat salivary glands: a comparison between tissue slices and homogenates. Acta Pharmacol Toxicol (Copenh). 1969; 27(1):73-80.
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  • Jonason J. Effects of reserpine on the noradrenaline content of atrophied rat salivary glands. Acta Physiol Scand. 1969 Jan-Feb; 75(1):73-7.
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  • Jonason J. Metabolism of catecholamines in the central and peripheral nervous system. A study with special reference to the enzymes involved. Acta Physiol Scand Suppl. 1969; 320:1-50.
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  • Dahlström A, Jonason J. DOPA-decarboxylase activity in sciatic nerves of the rat after constriction. Eur J Pharmacol. 1968 Nov; 4(4):377-83.
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  • Rutledge CO, Jonason J. The rate of metabolism of dopamine, dihydroxyphenylacetic acid and methoxytyramine in rabbit brain in vitro. Eur J Pharmacol. 1968 Oct; 4(3):264-9.
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  • Jonason J, Rutledge CO. Metabolism of dopamine and noradrenaline in rabbit caudate nucleus in vitro. Acta Physiol Scand. 1968 Aug; 73(4):411-7.
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  • Jonason J, Rutledge CO. The effect of protriptyline on the metabolism of dopamine and noradrenaline in rabbit brain in vitro. Acta Physiol Scand. 1968 May-Jun; 73(1):161-75.
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  • Rutledge CO, Jonason J. Metabolic pathways of dopamine and norepinephrine in rabbit brain in vitro. J Pharmacol Exp Ther. 1967 Sep; 157(3):493-502.
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  • Almgren O, Andén NE, Jonason J, Norberg KA, Olson L. Cellular localization of monoamine oxidase in rat salivary glands. Acta Physiol Scand. 1966 May; 67(1):21-6.
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