Pradyumna Phatak
| Title | Clinical Professor |
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| Institution | School of Medicine and Dentistry |
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| Department | Medicine |
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| Address | Rochester General Hospital
1425 Portland Avenue
Hematology Unit
Rochester NY 14621
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Imran FS, Phatak P. Deferasirox induced liver injury in haemochromatosis. J Coll Physicians Surg Pak. 2011 Nov; 21(11):718.
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Faltas B, Phatak P, Sham R. Mental nerve neuropathy: frequently overlooked clinical sign of hematologic malignancies. Am J Med. 2011 Jan; 124(1):e1-2.
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Phatak P, Brissot P, Wurster M, Adams PC, Bonkovsky HL, Gross J, Malfertheiner P, McLaren GD, Niederau C, Piperno A, Powell LW, Russo MW, Stoelzel U, Stremmel W, Griffel L, Lynch N, Zhang Y, Pietrangelo A. A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis. Hepatology. 2010 Nov; 52(5):1671-779.
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Imran F, Phatak P. Pharmacoeconomic benefits of deferasirox in the management of iron overload syndromes. Expert Rev Pharmacoecon Outcomes Res. 2009 Aug; 9(4):297-304.
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Sham RL, Phatak PD, Nemeth E, Ganz T. Hereditary hemochromatosis due to resistance to hepcidin: high hepcidin concentrations in a family with C326S ferroportin mutation. Blood. 2009 Jul 9; 114(2):493-4.
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Cheng R, Barton JC, Morrison ED, Phatak PD, Krawitt EL, Gordon SC, Kowdley KV. Differences in hepatic phenotype between hemochromatosis patients with HFE C282Y homozygosity and other HFE genotypes. J Clin Gastroenterol. 2009 Jul; 43(6):569-73.
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Delea TE, Hagiwara M, Phatak PD. Retrospective study of the association between transfusion frequency and potential complications of iron overload in patients with myelodysplastic syndrome and other acquired hematopoietic disorders. Curr Med Res Opin. 2009 Jan; 25(1):139-47.
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Phatak PD, Bonkovsky HL, Kowdley KV. Hereditary hemochromatosis: time for targeted screening. Ann Intern Med. 2008 Aug 19; 149(4):270-2.
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Gordeuk VR, Reboussin DM, McLaren CE, Barton JC, Acton RT, McLaren GD, Harris EL, Reiss JA, Adams PC, Speechley M, Phatak PD, Sholinsky P, Eckfeldt JH, Chen WP, Passmore L, Dawkins FW. Serum ferritin concentrations and body iron stores in a multicenter, multiethnic primary-care population. Am J Hematol. 2008 Aug; 83(8):618-26.
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Delea TE, Hagiwara M, Thomas SK, Baladi JF, Phatak PD, Coates TD. Outcomes, utilization, and costs among thalassemia and sickle cell disease patients receiving deferoxamine therapy in the United States. Am J Hematol. 2008 Apr; 83(4):263-70.
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Zeidan A, Phatak P. Acquired biclonal chromosome X aberrations without autosomal chromosomal anomalies in acute myeloid leukemia. Cancer Genet Cytogenet. 2008 Mar; 181(2):125-30.
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Delea TE, Edelsberg J, Sofrygin O, Thomas SK, Baladi JF, Phatak PD, Coates TD. Consequences and costs of noncompliance with iron chelation therapy in patients with transfusion-dependent thalassemia: a literature review. Transfusion. 2007 Oct; 47(10):1919-29.
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Delea TE, Sofrygin O, Thomas SK, Baladi JF, Phatak PD, Coates TD. Cost effectiveness of once-daily oral chelation therapy with deferasirox versus infusional deferoxamine in transfusion-dependent thalassaemia patients: US healthcare system perspective. Pharmacoeconomics. 2007; 25(4):329-42.
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Rajda J, Phatak PD. Reversible drug-induced interstitial pneumonitis following imatinib mesylate therapy. Am J Hematol. 2005 May; 79(1):80-1.
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Sham RL, Phatak PD, West C, Lee P, Andrews C, Beutler E. Autosomal dominant hereditary hemochromatosis associated with a novel ferroportin mutation and unique clinical features. Blood Cells Mol Dis. 2005 Mar-Apr; 34(2):157-61.
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Phatak PD, Barton JC. Phlebotomy-mobilized iron as a surrogate for liver iron content in hemochromatosis patients. Hematology. 2003 Dec; 8(6):429-32.
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Morrison ED, Brandhagen DJ, Phatak PD, Barton JC, Krawitt EL, El-Serag HB, Gordon SC, Galan MV, Tung BY, Ioannou GN, Kowdley KV. Serum ferritin level predicts advanced hepatic fibrosis among U.S. patients with phenotypic hemochromatosis. Ann Intern Med. 2003 Apr 15; 138(8):627-33.
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Ross JM, Kowalchuk RM, Shaulinsky J, Ross L, Ryan D, Phatak PD. Association of heterozygous hemochromatosis C282Y gene mutation with hand osteoarthritis. J Rheumatol. 2003 Jan; 30(1):121-5.
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Phatak PD, Ryan DH, Cappuccio J, Oakes D, Braggins C, Provenzano K, Eberly S, Sham RL. Prevalence and penetrance of HFE mutations in 4865 unselected primary care patients. Blood Cells Mol Dis. 2002 Jul-Aug; 29(1):41-7.
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Sham RL, Raubertas RF, Braggins C, Cappuccio J, Gallagher M, Phatak PD. Asymptomatic hemochromatosis subjects: genotypic and phenotypic profiles. Blood. 2000 Dec 1; 96(12):3707-11.
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Kouides PA, Phatak PD, Burkart P, Braggins C, Cox C, Bernstein Z, Belling L, Holmberg P, MacLaughlin W, Howard F. Gynaecological and obstetrical morbidity in women with type I von Willebrand disease: results of a patient survey. Haemophilia. 2000 Nov; 6(6):643-8.
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Sham RL, Phatak PD, Kouides PA, Janas JA, Marder VJ. Hematologic neoplasia and the central nervous system. Am J Hematol. 1999 Dec; 62(4):234-8.
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Phatak PD, Sham RL, Raubertas RF, Dunnigan K, O'Leary MT, Braggins C, Cappuccio JD. Prevalence of hereditary hemochromatosis in 16031 primary care patients. Ann Intern Med. 1998 Dec 1; 129(11):954-61.
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McDonnell SM, Phatak PD, Felitti V, Hover A, McLaren GD. Screening for hemochromatosis in primary care settings. Ann Intern Med. 1998 Dec 1; 129(11):962-70.
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Phatak PD, Janas JS, Kouides P, Leisveld J, Shafer J, Marder VJ. Infections affecting blood cell morphology. Am J Hematol. 1998 Nov; 59(3):238-41.
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Sham RL, Phatak PD. Hepatic iron index: how useful is it? Gastroenterology. 1998 May; 114(5):1112-3.
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Phatak PD, Janas JS, Sham RL, Yirinec B, Marder VJ. Disorders that resemble lymphomas. Am J Hematol. 1997 Sep; 56(1):63-8.
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Sham RL, Ou CY, Cappuccio J, Braggins C, Dunnigan K, Phatak PD. Correlation between genotype and phenotype in hereditary hemochromatosis: analysis of 61 cases. Blood Cells Mol Dis. 1997 Aug; 23(2):314-20.
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Ifthikharuddin JJ, Janas J, Phatak PD. Isolated splenic blastic transformation of idiopathic myelofibrosis and response to splenectomy. Leuk Res. 1997 Mar; 21(3):255-7.
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Phatak PD, Janas JS, Kouides PA, Sham RL, Marder VJ. Unusual anemias. Am J Hematol. 1997 Mar; 54(3):249-52.
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Menache D, Aronson DL, Darr F, Montgomery RR, Gill JC, Kessler CM, Lusher JM, Phatak PD, Shapiro AD, Thompson AR, White GC. Pharmacokinetics of von Willebrand factor and factor VIIIC in patients with severe von Willebrand disease (type 3 VWD): estimation of the rate of factor VIIIC synthesis. Cooperative Study Groups. Br J Haematol. 1996 Sep; 94(4):740-5.
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Phatak PD, Sham RL, Cappuccio JD. Screening for hemochromatosis: additional considerations. Gastroenterology. 1996 Feb; 110(2):653-4.
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Seese NK, Venditti CP, Chorney KA, Gerhard GS, Ma J, Hudson TJ, Phatak PD, Chorney MJ. Localization of the hemochromatosis disease gene: linkage disequilibrium analysis using an American patient collection. Blood Cells Mol Dis. 1996; 22(1):36-46; discussion 47-8.
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Sham RL, Phatak PD, Belanger KA, Packman CH. The effect of dexamethasone on functional properties of HL60 cells during all-trans retinoic acid induced differentiation. Are there implications for the retinoic acid syndrome? Blood Cells Mol Dis. 1996; 22(2):139-49.
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Beutler E, Gelbart T, West C, Lee P, Adams M, Blackstone R, Pockros P, Kosty M, Venditti CP, Phatak PD, Seese NK, Chorney KA, Ten Elshof AE, Gerhard GS, Chorney M. Mutation analysis in hereditary hemochromatosis. Blood Cells Mol Dis. 1996; 22(2):187-94; discussion 194a-194b.
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Kouides PA, Phatak PD, Cramer SF. Fatal thrombotic thrombocytopenic purpura (TTP) presenting concurrently with metastatic multiple endocrine neoplasia (MEN) type I. Hematopathol Mol Hematol. 1996; 10(3):161-70.
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Sham RL, Phatak PD, Belanger KA, Braggins C, Packman CH. Functional characteristics of mature granulocytes in a patient with acute promyelocytic leukemia treated with all-trans retinoic acid. Leuk Res. 1995 Aug; 19(8):505-11.
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Reykdal S, Sham R, Phatak P, Kouides P. Pseudoleukemia following the use of G-CSF. Am J Hematol. 1995 Jul; 49(3):258-9.
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Sham RL, Phatak PD, Belanger KA, Packman CH. Functional properties of HL60 cells matured with all-trans-retinoic acid and DMSO: differences in response to interleukin-8 and fMLP. Leuk Res. 1995 Jan; 19(1):1-6.
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Phatak PD, Cappuccio JD. Management of hereditary hemochromatosis. Blood Rev. 1994 Dec; 8(4):193-8.
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Kouides PA, Phatak PD, Wang N, Bennett JM. B-cell acute lymphoblastic leukemia with L1 morphology and coexistence of t(1;19) and t(14;18) chromosome translocations. Cancer Genet Cytogenet. 1994 Nov; 78(1):23-7.
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Cappuccio J, Phatak P. Preventive health services. N Engl J Med. 1994 Oct 27; 331(17):1157; author reply 1157-8.
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Phatak PD, Packman CH. Engagement of the T-cell antigen receptor by anti-CD3 monoclonal antibody causes a rapid increase in lymphocyte F-actin. J Cell Physiol. 1994 May; 159(2):365-70.
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Phatak PD, Guzman G, Woll JE, Robeson A, Phelps CE. Cost-effectiveness of screening for hereditary hemochromatosis. Arch Intern Med. 1994 Apr 11; 154(7):769-76.
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Sham RL, Phatak PD, Ihne TP, Abboud CN, Packman CH. Signal pathway regulation of interleukin-8-induced actin polymerization in neutrophils. Blood. 1993 Oct 15; 82(8):2546-51.
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Sham RL, Phatak P, Carignan J, Janas J, Olson JP. Progression of follicular large cell lymphoma to Burkitt's lymphoma. Cancer. 1989 Feb 15; 63(4):700-2.
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Phatak PD, Packman CH, Lichtman MA. Protein kinase C modulates actin conformation in human T lymphocytes. J Immunol. 1988 Nov 1; 141(9):2929-34.
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