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James Burchfiel

TitleProfessor (Part-Time)
InstitutionSchool of Medicine and Dentistry
DepartmentNeurology
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 673
Rochester NY 14642
 
 Awards And Honors
1979     Special Reviewer, Neurological Sciences Study Section  | Division of Research Grants, NIH
1980     Member, Special Study Section  | Division of Research Grants, NIH
1981     Member, Special Site Visit Study Section  | Division of Research Grants, NIH
1981     Member, Special Study Section  | Division of Research Grants, NIH
1982     Member, Site Visit Committee  | Neurology A Study Section Division of Research Grants, NIH
1982 - 1983Junior to Senior Councilor  | Eastern Association of Electroencephalographers
1983     Special Reviewer, Neurological Sciences Study Section  | Division of Research Grants, NIH
1983     Special Research Program Review Committee  | Department of Defense, Medical Research Laboratory,
1983 - 1986Secretary/Treasurer  | Eastern Association of Electroencephalographers
1983 - 1990Committee on Technical Matters, Long-term Monitoring  | American Electroencephalographic Society
1985 - 1986Program Committee  | American Epilepsy Society
1985 - 1990Program Committee, Eastern Association of Electroencephalographers
1986 - 1987President-Elect, Eastern Association of Electroencephalographers
1986 - 1990Chartered Member, Neurology A Study Section  | Division of Research Grants, NIH
1988 - 1989President, Eastern Association of Electroencephalographers
1990 - 1992Childhood Epilepsy Committee  | American Epilepsy Society
1990 - 1993Chair, Long-Range Planning Committee  | Eastern Association of Electroencephalographers
1991     Consultant, NINDS Neurological Disorders Program Project Review A Committee,  | NIH
1993 - 1995Medical Instrumentation Committee  | American Electroencephalographic Society
1994 - 1997Investigators' Workshop Committee  | American Epilespy Society
1996     Practice of Clinical Neurophysiology Committee  | American Clinical Neurophysiology Society
 
 Overview
James L. Burchfiel, Ph.D. is Professor of Neurology at the University of Rochester, New York. His clinical interest is in the neurophysiology of epilepsy and other neurological disorders.

Dr. Burchfiel received both his undergraduate and graduate education at Stanford University. After serving for 2 years as a Captain in the US Army, working in the research laboratories of Edgewood Arsenal, Maryland, he joined the faculty of the Seizure Unit, Department of Neurology, Children's Hospital, Boston and the Harvard Medical School. There, he completed fellowship training in clinical neurophysiology and served as an attending clinical neurophysiologist. In addition, he conducted independent NIH-sponsored basic research in epilepsy.

In 1989, Dr. Burchfiel, with his long-time colleague Dr. Giuseppe Erba, moved to the University of Rochester to found the Strong Epilepsy Center. Dr. Burchfiel served as Co-Director with Dr. Erba until 2000 and was Director from 2000 to 2006.

Dr. Burchfiel has published over 50 peer-reviewed articles and reviews and continues to have an active interest in both basic and clinical research in epilepsy. Most recently he has been involved in two main projects: (1) establishing a web-based atlas of EEG seizure data to be used by researchers throughout the world for testing of seizure-detection algorithms and (2) collaboration with a group of basic researchers at the National Academy of Sciences of the Czech Republic to develop and test better animals models of epilepsy.

He is an active member of the Eastern Association of Electroencephalographers, the American Clinical Neurophysiology Society and the American Epilepsy Society and has held offices and served on committees and boards for these organizations. In addition, he is a past member of an NIH grant review study section.

 
 Selected Publications
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  1. Seltzer LE, Swartz M, Kwon JM, Burchfiel J, Alfieris GM, Guillet R. Intraoperative electroencephalography predicts postoperative seizures in infants with congenital heart disease. Pediatr Neurol. 2014 Apr; 50(4):313-7.
    View in: PubMed
  2. Illig KA, Sternbach Y, Zhang R, Burchfiel J, Shortell CK, Rhodes JM, Davies MG, Lyden SP, Green RM. EEG changes during awake carotid endarterectomy. Ann Vasc Surg. 2002 Jan; 16(1):6-11.
    View in: PubMed
  3. Illig KA, Burchfiel JL, Ouriel K, DeWeese JA, Shortell CK, Green RM. Value of preoperative EEG for carotid endarterectomy. Cardiovasc Surg. 1998 Oct; 6(5):490-5.
    View in: PubMed
  4. Laroia N, Guillet R, Burchfiel J, McBride MC. EEG background as predictor of electrographic seizures in high-risk neonates. Epilepsia. 1998 May; 39(5):545-51.
    View in: PubMed
  5. Applegate CD, Jensen F, Burchfiel JL, Lombroso C. The effects of neonatal hypoxia on kindled seizure development and electroconvulsive shock profiles. Epilepsia. 1996 Aug; 37(8):723-7.
    View in: PubMed
  6. Oestreich LJ, Berg MJ, Bachmann DL, Burchfiel J, Erba G. Ictal contralateral paresis in complex partial seizures. Epilepsia. 1995 Jul; 36(7):671-5.
    View in: PubMed
  7. Engel J, Burchfiel J, Ebersole J, Gates J, Gotman J, Homan R, Ives J, King D, Lieb J, Sato S, et al. Long-term monitoring for epilepsy. Report of an IFCN committee. Electroencephalogr Clin Neurophysiol. 1993 Dec; 87(6):437-58.
    View in: PubMed
  8. Applegate CD, Samoriski GM, Burchfiel JL. Evidence for the interaction of brainstem systems mediating seizure expression in kindling and electroconvulsive shock seizure models. Epilepsy Res. 1991 Nov-Dec; 10(2-3):142-7.
    View in: PubMed
  9. Jensen FE, Applegate CD, Holtzman D, Belin TR, Burchfiel JL. Epileptogenic effect of hypoxia in the immature rodent brain. Ann Neurol. 1991 Jun; 29(6):629-37.
    View in: PubMed
  10. Jensen FE, Applegate C, Burchfiel J, Lombroso CT. Differential effects of perinatal hypoxia and anoxia on long term seizure susceptibility in the rat. Life Sci. 1991; 49(5):399-407.
    View in: PubMed
  11. DeLeo JA, Applegate CD, Burchfiel JL, Lorenzo AV, Hsi DH. Perinatal exposure to anoxia alone does not alter the susceptibility to amygdaloid-kindled seizures in the adult rabbit. Brain Res. 1990 Jul 2; 522(1):168-71.
    View in: PubMed
  12. Applegate CD, Burchfiel JL. Evidence for a norepinephrine-dependent brain-stem substrate in the development of kindling antagonism. Epilepsy Res. 1990 May-Jun; 6(1):23-32.
    View in: PubMed
  13. Burchfiel JL, Applegate CD. Stepwise progression of kindling: perspectives from the kindling antagonism model. Neurosci Biobehav Rev. 1989; 13(4):289-99.
    View in: PubMed
  14. Applegate CD, Burchfiel JL. Microinjections of GABA agonists into the amygdala complex attenuates kindled seizure expression in the rat. Exp Neurol. 1988 Nov; 102(2):185-9.
    View in: PubMed
  15. Waszczak BL, Applegate CD, Burchfiel JL. Kindling does not cause persistent changes in firing rates or transmitter sensitivities of substantia nigra pars reticulata neurons. Brain Res. 1988 Jul 5; 455(1):115-22.
    View in: PubMed
  16. Applegate CD, Konkol RJ, Burchfiel JL. Kindling antagonism: a role for hindbrain norepinephrine in the development of site suppression following concurrent, alternate stimulation. Brain Res. 1987 Mar 31; 407(2):212-22.
    View in: PubMed
  17. Lombroso CT, Burchfiel JL. Etiologic and preventive aspects of epilepsy in the child--bridging the gap between laboratory and clinic. Epilepsia. 1987; 28 Suppl 1:S25-35.
    View in: PubMed
  18. Applegate CD, Flashman LA, Burchfiel JL. The effects of chronic desmethylimipramine on entorhinal cortical kindling in rats. Brain Res. 1986 Nov 19; 398(1):121-7.
    View in: PubMed
  19. Applegate CD, Burchfiel JL, Konkol RJ. Kindling antagonism: effects of norepinephrine depletion on kindled seizure suppression after concurrent, alternate stimulation in rats. Exp Neurol. 1986 Nov; 94(2):379-90.
    View in: PubMed
  20. Duffy FH, Burchfiel JL, Mower GD, Joy RM, Snodgrass SR. Comparative pharmacological effects on visual cortical neurons in monocularly deprived cats. Brain Res. 1985 Jul 29; 339(2):257-64.
    View in: PubMed
  21. Mower GD, Christen WG, Burchfiel JL, Duffy FH. Microiontophoretic bicuculline restores binocular responses to visual cortical neurons in strabismic cats. Brain Res. 1984 Aug 20; 309(1):168-72.
    View in: PubMed
  22. Duffy FH, Jensen F, Erba G, Burchfiel JL, Lombroso CT. Extraction of clinical information from electroencephalographic background activity: the combined use of brain electrical activity mapping and intravenous sodium thiopental. Ann Neurol. 1984 Jan; 15(1):22-30.
    View in: PubMed
  23. Mower GD, Burchfiel JL, Duffy FH. Animal models of strabismic amblyopia: physiological studies of visual cortex and the lateral geniculate nucleus. Brain Res. 1982 Nov; 281(3):311-27.
    View in: PubMed
  24. Burchfiel JL, Duffy FH. Organophosphate neurotoxicity: chronic effects of sarin on the electroencephalogram of monkey and man. Neurobehav Toxicol Teratol. 1982 Nov-Dec; 4(6):767-78.
    View in: PubMed
  25. Burchfiel JL, Serpa KA, Duffy FH. Kindling antagonism: interactions of dorsal and ventral entorhinal cortex with the septum during concurrent kindling. Brain Res. 1982 Apr 22; 238(1):3-12.
    View in: PubMed
  26. Burchfiel JL, Serpa KA, Duffy FH. Further studies of antagonism of seizure development between concurrently developing kindled limbic foci in the rat. Exp Neurol. 1982 Feb; 75(2):476-89.
    View in: PubMed
  27. Mower GD, Berry D, Burchfiel JL, Duffy FH. Comparison of the effects of dark rearing and binocular suture on development and plasticity of cat visual cortex. Brain Res. 1981 Sep 14; 220(2):255-67.
    View in: PubMed
  28. Mower GD, Burchfiel JL, Duffy FH. The effects of dark-rearing on the development and plasticity of the lateral geniculate nucleus. Brain Res. 1981 Jun; 227(3):418-24.
    View in: PubMed
  29. Duffy FH, Bartels PH, Burchfiel JL. Significance probability mapping: an aid in the topographic analysis of brain electrical activity. Electroencephalogr Clin Neurophysiol. 1981 May; 51(5):455-62.
    View in: PubMed
  30. Duchowny MS, Burchfiel JL. Facilitation and antagonism of kindled seizure development in the limbic system of the rat. Electroencephalogr Clin Neurophysiol. 1981 Apr; 51(4):403-16.
    View in: PubMed
  31. Burchfiel JL, Duffy FH. Role of intracortical inhibition in deprivation amblyopia: reversal by microiontophoretic bicuculline. Brain Res. 1981 Feb 16; 206(2):479-84.
    View in: PubMed
  32. Burchfiel JL, Duchowny MS, Duffy FH. Neuronal supersensitivity to acetylcholine induced by kindling in the rat hippocampus. Science. 1979 Jun 8; 204(4397):1096-8.
    View in: PubMed
  33. Duffy FH, Burchfiel JL, Lombroso CT. Brain electrical activity mapping (BEAM): a method for extending the clinical utility of EEG and evoked potential data. Ann Neurol. 1979 Apr; 5(4):309-21.
    View in: PubMed
  34. Duffy FH, Burchfiel JL, Bartels PH, Gaon M, Sim VM. Long-term effects of an organophosphate upon the human electroencephalogram. Toxicol Appl Pharmacol. 1979 Jan; 47(1):161-76.
    View in: PubMed
  35. Duffy FH, Burchfiel JL, Snodgrass SR. The pharmacology of amblyopia. Ophthalmology. 1978 May; 85(5):489-95.
    View in: PubMed
  36. Duffy FH, Burchfiel JL, Conway JL. Bicuculline reversal of deprivation amblyopia in the cat. Nature. 1976 Mar 18; 260(5548):256-7.
    View in: PubMed
  37. Burchfiel JL, Duffy FH, Van Sim M. Persistent effects of sarin and dieldrin upon the primate electroencephalogram. Toxicol Appl Pharmacol. 1976 Feb; 35(2):365-79.
    View in: PubMed
  38. Duffy FH, Burchfiel JL. Eye movement-related inhibition of primate visual neurons. Brain Res. 1975 May 16; 89(1):121-32.
    View in: PubMed
  39. Burchfiel JE, Duffy FH. Corticofugal influence upon cat thalamic ventrobasal complex. Brain Res. 1974 Apr 26; 70(3):395-411.
    View in: PubMed
  40. Burchfiel JL, Duffy FH. Muscle afferent input to single cells in primate somatosensory cortex. Brain Res. 1972 Oct 13; 45(1):241-6.
    View in: PubMed
  41. Duffy FH, Burchfiel JL. Somatosensory system: organizational hierarchy from single units in monkey area 5. Science. 1971 Apr 16; 172(3980):273-5.
    View in: PubMed
  42. Burchfiel JL, Duffy FH. Tonic cortico-thalamic inhibition in the somatosensory system of the cat. Electroencephalogr Clin Neurophysiol. 1970 Oct; 29(4):410.
    View in: PubMed

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