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Nancy Krieger

TitleResearch Associate Professor
InstitutionSchool of Medicine and Dentistry
DepartmentMedicine
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 675
Rochester NY 14642
Other Positions
TitleResearch Associate Professor
InstitutionSchool of Medicine and Dentistry
DepartmentPharmacology and Physiology

 
 Selected Publications
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  1. Frick KK, Asplin JR, Krieger NS, Culbertson CD, Asplin DM, Bushinsky DA. 1,25(OH)2D3-enhanced hypercalciuria in genetic hypercalciuric stone-forming rats fed a low-calcium diet. Am J Physiol Renal Physiol. 2013 Oct; 305(8):F1132-8.
    View in: PubMed
  2. Frick KK, Asplin JR, Favus MJ, Culbertson C, Krieger NS, Bushinsky DA. Increased biological response to 1,25(OH)2D3 in genetic hypercalciuric stone-forming rats. Am J Physiol Renal Physiol. 2013 Mar; 304(6):F718-26.
    View in: PubMed
  3. Krieger NS, Bushinsky DA. The relation between bone and stone formation. Calcif Tissue Int. 2013 Oct; 93(4):374-81.
    View in: PubMed
  4. Krieger NS, Culbertson CD, Kyker-Snowman K, Bushinsky DA. Metabolic acidosis increases fibroblast growth factor 23 in neonatal mouse bone. Am J Physiol Renal Physiol. 2012 Aug 1; 303(3):F431-6.
    View in: PubMed
  5. Krieger NS, Bushinsky DA. Pharmacological inhibition of intracellular calcium release blocks acid-induced bone resorption. Am J Physiol Renal Physiol. 2011 Jan; 300(1):F91-7.
    View in: PubMed
  6. Frick KK, Krieger NS, Nehrke K, Bushinsky DA. Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1. J Bone Miner Res. 2009 Feb; 24(2):305-13.
    View in: PubMed
  7. Krieger NS, Frick KK, LaPlante Strutz K, Michalenka A, Bushinsky DA. Regulation of COX-2 mediates acid-induced bone calcium efflux in vitro. J Bone Miner Res. 2007 Jun; 22(6):907-17.
    View in: PubMed
  8. Krieger NS, Frick KK, Bushinsky DA. Mechanism of acid-induced bone resorption. Curr Opin Nephrol Hypertens. 2004 Jul; 13(4):423-36.
    View in: PubMed
  9. Krieger NS, Bushinsky DA, Frick KK. Cellular mechanisms of bone resorption induced by metabolic acidosis. Semin Dial. 2003 Nov-Dec; 16(6):463-6.
    View in: PubMed
  10. Krieger NS, Frick KK, Bushinsky DA. Cortisol inhibits acid-induced bone resorption in vitro. J Am Soc Nephrol. 2002 Oct; 13(10):2534-9.
    View in: PubMed
  11. Bushinsky DA, Parker WR, Alexander KM, Krieger NS. Metabolic, but not respiratory, acidosis increases bone PGE(2) levels and calcium release. Am J Physiol Renal Physiol. 2001 Dec; 281(6):F1058-66.
    View in: PubMed
  12. Krieger NS, Parker WR, Alexander KM, Bushinsky DA. Prostaglandins regulate acid-induced cell-mediated bone resorption. Am J Physiol Renal Physiol. 2000 Dec; 279(6):F1077-82.
    View in: PubMed
  13. Bushinsky DA, Neumann KJ, Asplin J, Krieger NS. Alendronate decreases urine calcium and supersaturation in genetic hypercalciuric rats. Kidney Int. 1999 Jan; 55(1):234-43.
    View in: PubMed
  14. Bushinsky DA, Riordon DR, Chan JS, Krieger NS. Decreased potassium stimulates bone resorption. Am J Physiol. 1997 Jun; 272(6 Pt 2):F774-80.
    View in: PubMed
  15. Krieger NS. Parathyroid hormone, prostaglandin E2, and 1,25-dihydroxyvitamin D3 decrease the level of Na+-Ca2+ exchange protein in osteoblastic cells. Calcif Tissue Int. 1997 May; 60(5):473-8.
    View in: PubMed
  16. Bushinsky DA, Gavrilov K, Stathopoulos VM, Krieger NS, Chabala JM, Levi-Setti R. Effects of osteoclastic resorption on bone surface ion composition. Am J Physiol. 1996 Oct; 271(4 Pt 1):C1025-31.
    View in: PubMed
  17. Krieger NS, Stathopoulos VM, Bushinsky DA. Increased sensitivity to 1,25(OH)2D3 in bone from genetic hypercalciuric rats. Am J Physiol. 1996 Jul; 271(1 Pt 1):C130-5.
    View in: PubMed
  18. Krieger NS. Calcemic hormones regulate the level of sodium-calcium exchange protein in osteoblastic cells. Ann N Y Acad Sci. 1996 Apr 15; 779:293-4.
    View in: PubMed
  19. Ori Y, Lee SG, Krieger NS, Bushinsky DA. Osteoblastic intracellular pH and calcium in metabolic and respiratory acidosis. Kidney Int. 1995 Jun; 47(6):1790-6.
    View in: PubMed
  20. Sprague SM, Krieger NS, Bushinsky DA. Greater inhibition of in vitro bone mineralization with metabolic than respiratory acidosis. Kidney Int. 1994 Oct; 46(4):1199-206.
    View in: PubMed
  21. Short CL, Monk RD, Bushinsky DA, Krieger NS. Hormonal regulation of Na(+)-Ca2+ exchange in osteoblast-like cells. J Bone Miner Res. 1994 Aug; 9(8):1159-66.
    View in: PubMed
  22. Sprague SM, Krieger NS, Bushinsky DA. Aluminum inhibits bone nodule formation and calcification in vitro. Am J Physiol. 1993 May; 264(5 Pt 2):F882-90.
    View in: PubMed
  23. Krieger NS. Demonstration of sodium/calcium exchange in rodent osteoblasts. J Bone Miner Res. 1992 Sep; 7(9):1105-11.
    View in: PubMed
  24. Bushinsky DA, Sessler NE, Krieger NS. Greater unidirectional calcium efflux from bone during metabolic, compared with respiratory, acidosis. Am J Physiol. 1992 Mar; 262(3 Pt 2):F425-31.
    View in: PubMed
  25. Krieger NS, Sessler NE, Bushinsky DA. Acidosis inhibits osteoblastic and stimulates osteoclastic activity in vitro. Am J Physiol. 1992 Mar; 262(3 Pt 2):F442-8.
    View in: PubMed
  26. Krieger NS. Evidence for sodium-calcium exchange in rodent osteoblasts. Ann N Y Acad Sci. 1991; 639:660-2.
    View in: PubMed
  27. Blair NF, Krieger NS, Bushinsky DA. Mechanism of amphotericin B stimulation of net calcium efflux from neonatal mouse calvariae. J Bone Miner Res. 1990 Jul; 5(7):725-32.
    View in: PubMed
  28. Krieger NS, Sukhatme VP, Bushinsky DA. Conditioned medium from ras oncogene-transformed NIH 3T3 cells induces bone resorption in vitro. J Bone Miner Res. 1990 Feb; 5(2):159-64.
    View in: PubMed
  29. Lucas RC, Seidenfeld J, Krieger NS, Stern PH. Inhibition of bone resorption by alpha-difluoromethylornithine may not be mediated by polyamine depletion. J Bone Miner Res. 1989 Dec; 4(6):901-9.
    View in: PubMed
  30. Krieger NS, Hefley TJ. Differential effects of parathyroid hormone on protein phosphorylation in two osteoblastlike cell populations isolated from neonatal mouse calvaria. Calcif Tissue Int. 1989 Mar; 44(3):192-9.
    View in: PubMed
  31. Krieger NS, Stappenbeck TS, Stern PH. Characterization of specific thyroid hormone receptors in bone. J Bone Miner Res. 1988 Aug; 3(4):473-8.
    View in: PubMed
  32. Krieger NS, Kim SG. Dichlorobenzamil inhibits stimulated bone resorption in vitro. Endocrinology. 1988 Feb; 122(2):415-20.
    View in: PubMed
  33. Krieger NS, Stappenbeck TS, Stern PH. Cardiotonic agent milrinone stimulates resorption in rodent bone organ culture. J Clin Invest. 1987 Feb; 79(2):444-8.
    View in: PubMed
  34. Krieger NS, Stern PH. Effects of forskolin on bone in organ culture. Am J Physiol. 1987 Jan; 252(1 Pt 1):E44-8.
    View in: PubMed
  35. Krieger NS, Stathopoulos VM, Stern PH. Does amrinone inhibition of stimulated bone resorption involve Na+-Ca++ exchange? Circulation. 1986 Mar; 73(3 Pt 2):III59-64.
    View in: PubMed
  36. Hefley TJ, Krieger NS, Stern PH. Simultaneous measurement of bone resorption and collagen synthesis in neonatal mouse calvaria. Anal Biochem. 1986 Feb 15; 153(1):166-71.
    View in: PubMed
  37. Stern PH, Krieger NS, Nissenson RA, Williams RD, Winkler ME, Derynck R, Strewler GJ. Human transforming growth factor-alpha stimulates bone resorption in vitro. J Clin Invest. 1985 Nov; 76(5):2016-9.
    View in: PubMed
  38. Warner MR, Rappaport MS, Krieger NS, Novak RF, Stern PH. Ametantrone inhibits prostaglandin--mediated resorption in bone organ culture. Prostaglandins. 1984 Oct; 28(4):469-76.
    View in: PubMed
  39. Krieger NS, Stern PH. Potassium effects on bone: comparison of two model systems. Am J Physiol. 1983 Sep; 245(3):E303-7.
    View in: PubMed
  40. Bushinsky DA, Krieger NS, Geisser DI, Grossman EB, Coe FL. Effects of pH on bone calcium and proton fluxes in vitro. Am J Physiol. 1983 Aug; 245(2):F204-9.
    View in: PubMed
  41. Krieger NS, Tashjian AH. Inhibition of stimulated bone resorption by vanadate. Endocrinology. 1983 Jul; 113(1):324-8.
    View in: PubMed
  42. Stern PH, Krieger NS. Comparison of fetal rat limb bones and neonatal mouse calvaria: effects of parathyroid hormone and 1,25-dihydroxyvitamin D3. Calcif Tissue Int. 1983; 35(2):172-6.
    View in: PubMed
  43. Krieger NS, Stern PH. Interaction between amrinone and parathyroid hormone on bone in culture. Am J Physiol. 1982 Dec; 243(6):E499-504.
    View in: PubMed
  44. Krieger NS, Tashjian AH. Inhibition of parathyroid hormone-stimulated bone resorption by monovalent cation ionophores. Calcif Tissue Int. 1982 May; 34(3):239-44.
    View in: PubMed
  45. Krieger NS, Feldman RS, Tashjian AH. Parathyroid hormone and calcitonin interactions in bone: irradiation-induced inhibition of escape in vitro. Calcif Tissue Int. 1982 Mar; 34(2):197-203.
    View in: PubMed
  46. Krieger NS, Tashjian AH. Inhibition by ouabain of parathyroid hormone-stimulated bone resorption. J Pharmacol Exp Ther. 1981 Jun; 217(3):586-91.
    View in: PubMed
  47. Krieger NS, Tashjian AH. Parathyroid hormone stimulates bone resorption via a Na-Ca exchange mechanism. Nature. 1980 Oct 30; 287(5785):843-5.
    View in: PubMed
  48. Feldman RS, Krieger NS, Tashjian AH. Effects of parathyroid hormone and calcitonin on osteoclast formation in vitro. Endocrinology. 1980 Oct; 107(4):1137-43.
    View in: PubMed

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