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Kevin Frick

TitleResearch Assistant Prof (Part-Time)
InstitutionSchool of Medicine and Dentistry
DepartmentMedicine
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 675
Rochester NY 14642
 
 Awards And Honors
1975     High Honors in Biochemistry
1975     Distinction in General Scholarship
1976 - 1979NSF Predoctoral Fellow
 
 Selected Publications
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  1. Frick KK, Asplin JR, Culbertson CD, Granja I, Krieger NS, Bushinsky DA. Persistence of 1,25D-induced hypercalciuria in alendronate-treated genetic hypercalciuric stone-forming rats fed a low-calcium diet. Am J Physiol Renal Physiol. 2014 May; 306(9):F1081-7.
    View in: PubMed
  2. Ng AH, Frick KK, Krieger NS, Asplin JR, Cohen-McFarlane M, Culbertson CD, Kyker-Snowman K, Grynpas MD, Bushinsky DA. 1,25(OH)2D 3 Induces a Mineralization Defect and Loss of Bone Mineral Density in Genetic Hypercalciuric Stone-Forming Rats. Calcif Tissue Int. 2014 May; 94(5):531-43.
    View in: PubMed
  3. Frick KK, Asplin JR, Krieger NS, Culbertson CD, Asplin DM, Bushinsky DA. 1,25(OH)2D3-enhanced hypercalciuria in genetic hypercalciuric stone-forming rats fed a low-calcium diet. Am J Physiol Renal Physiol. 2013 Oct; 305(8):F1132-8.
    View in: PubMed
  4. Frick KK, Asplin JR, Favus MJ, Culbertson C, Krieger NS, Bushinsky DA. Increased biological response to 1,25(OH)2D3 in genetic hypercalciuric stone-forming rats. Am J Physiol Renal Physiol. 2013 Mar; 304(6):F718-26.
    View in: PubMed
  5. Frick KK, Bushinsky DA. Effect of metabolic and respiratory acidosis on intracellular calcium in osteoblasts. Am J Physiol Renal Physiol. 2010 Aug; 299(2):F418-25.
    View in: PubMed
  6. Frick KK, Krieger NS, Nehrke K, Bushinsky DA. Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1. J Bone Miner Res. 2009 Feb; 24(2):305-13.
    View in: PubMed
  7. Krieger NS, Frick KK, LaPlante Strutz K, Michalenka A, Bushinsky DA. Regulation of COX-2 mediates acid-induced bone calcium efflux in vitro. J Bone Miner Res. 2007 Jun; 22(6):907-17.
    View in: PubMed
  8. Bushinsky DA, Frick KK, Nehrke K. Genetic hypercalciuric stone-forming rats. Curr Opin Nephrol Hypertens. 2006 Jul; 15(4):403-18.
    View in: PubMed
  9. Frick KK, LaPlante K, Bushinsky DA. RANK ligand and TNF-alpha mediate acid-induced bone calcium efflux in vitro. Am J Physiol Renal Physiol. 2005 Nov; 289(5):F1005-11.
    View in: PubMed
  10. Krieger NS, Frick KK, Bushinsky DA. Mechanism of acid-induced bone resorption. Curr Opin Nephrol Hypertens. 2004 Jul; 13(4):423-36.
    View in: PubMed
  11. Krieger NS, Bushinsky DA, Frick KK. Cellular mechanisms of bone resorption induced by metabolic acidosis. Semin Dial. 2003 Nov-Dec; 16(6):463-6.
    View in: PubMed
  12. Frick KK, Bushinsky DA. Metabolic acidosis stimulates RANKL RNA expression in bone through a cyclo-oxygenase-dependent mechanism. J Bone Miner Res. 2003 Jul; 18(7):1317-25.
    View in: PubMed
  13. Frick KK, Bushinsky DA. Molecular mechanisms of primary hypercalciuria. J Am Soc Nephrol. 2003 Apr; 14(4):1082-95.
    View in: PubMed
  14. Krieger NS, Frick KK, Bushinsky DA. Cortisol inhibits acid-induced bone resorption in vitro. J Am Soc Nephrol. 2002 Oct; 13(10):2534-9.
    View in: PubMed
  15. Bushinsky DA, Frick KK. The effects of acid on bone. Curr Opin Nephrol Hypertens. 2000 Jul; 9(4):369-79.
    View in: PubMed
  16. Frick KK, Bushinsky DA. In vitro metabolic and respiratory acidosis selectively inhibit osteoblastic matrix gene expression. Am J Physiol. 1999 Nov; 277(5 Pt 2):F750-5.
    View in: PubMed
  17. Frick KK, Bushinsky DA. Chronic metabolic acidosis reversibly inhibits extracellular matrix gene expression in mouse osteoblasts. Am J Physiol. 1998 Nov; 275(5 Pt 2):F840-7.
    View in: PubMed
  18. Frick KK, Jiang L, Bushinsky DA. Acute metabolic acidosis inhibits the induction of osteoblastic egr-1 and type 1 collagen. Am J Physiol. 1997 May; 272(5 Pt 1):C1450-6.
    View in: PubMed
  19. Furlanetto RW, Harwell SE, Frick KK. Insulin-like growth factor-I induces cyclin-D1 expression in MG63 human osteosarcoma cells in vitro. Mol Endocrinol. 1994 Apr; 8(4):510-7.
    View in: PubMed
  20. Frick KK, Scher CD. Platelet-derived growth factor-stimulated c-myc RNA accumulation in MG-63 human osteosarcoma cells is independent of both protein kinase A and protein kinase C. Mol Cell Biol. 1990 Jan; 10(1):184-92.
    View in: PubMed

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