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David Korones

TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentPediatrics
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 777
Rochester NY 14642
Other Positions
TitleProfessor
InstitutionUniversity of Rochester Medical Center
DepartmentCancer Center

TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentNeurology
DivisionNeurology - Child Neurology

 
 Awards And Honors
1992     American Society of Cinical Oncology Young Investigator Award
2000     The 2000 Miracle Maker Award for Outstanding Service by a Physician
2000     The Gitelman Award  | Cancer Action and Gilda's Club
2000     The Teddi Award  | Camp Good Days and Special Times
2004 - 2009Best Doctors in America list  | America's Best Doctors
2004     The Rising Star Humanitarian Award  | Make-a-Wish Foundation
2006     Leonard Tow Humanism in Medicine Award
2006     Make a Difference Award  | Melissa's Living Legacy Foundation
2007 - 2009America's Top Cancer Doctors
2008     Gold Humanism Honor Society
2009     Ruth A. Lawrence Academic Faculty Service Award in Clinical Services
2010     Camp Good Days and Special Times Ring of Honor
 
 Overview
My interests are focused on brain tumors in adults and children, and palliative care. I have conducted, and continue to conduct clinical trials for both children and adults with newly diagnosed and recurrent brain tumors. I have conducted a clinical trial through the Children's Oncology Group, and my current studies are local and multiinstitutional investigator-initiated pharmaceutical-sponsored trials. I also have written review articles and chapters on brain tumors and palliative care, and conducted retrospective studies related to palliative care for children with cancer.

 
 Selected Publications
  • Lou E, Sumrall AL, Cummings TJ, Korones DN, Weaver SA, Peters KB. Disseminated Intracranial Ewing's Sarcoma in an Adult: A Rare and Difficult Diagnosis. Case Rep Oncol. 2012 May; 5(2):325-31.
    View in: PubMed
  • Chawla S, Korones DN, Milano MT, Hussain A, Hussien AR, Muhs AG, Mangla M, Silberstein H, Ekholm S, Constine LS. Spurious progression in pediatric brain tumors. J Neurooncol. 2012 May; 107(3):651-7.
    View in: PubMed
  • Bredlau AL, Constine LS, Silberstein HJ, Milano MT, Korones DN. Incidental brain lesions in children: to treat or not to treat? J Neurooncol. 2012 Feb; 106(3):589-94.
    View in: PubMed
  • Khorana AA, Shayne M, Korones DN. Can literature enhance oncology training? A pilot humanities curriculum. J Clin Oncol. 2011 Feb 1; 29(4):468-71.
    View in: PubMed
  • Korones DN. Two hats. J Palliat Med. 2010 Dec; 13(12):1488-9.
    View in: PubMed
  • Korones DN. Living in the moment. J Clin Oncol. 2010 Nov 1; 28(31):4778-9.
    View in: PubMed
  • Mangla R, Singh G, Ziegelitz D, Milano MT, Korones DN, Zhong J, Ekholm SE. Changes in relative cerebral blood volume 1 month after radiation-temozolomide therapy can help predict overall survival in patients with glioblastoma. Radiology. 2010 Aug; 256(2):575-84.
    View in: PubMed
  • Milano MT, Okunieff P, Donatello RS, Mohile NA, Sul J, Walter KA, Korones DN. Patterns and timing of recurrence after temozolomide-based chemoradiation for glioblastoma. Int J Radiat Oncol Biol Phys. 2010 Nov 15; 78(4):1147-55.
    View in: PubMed
  • Epstein RM, Korones DN, Quill TE. Withholding information from patients--when less is more. N Engl J Med. 2010 Feb 4; 362(5):380-1.
    View in: PubMed
  • Milano MT, Johnson MD, Sul J, Mohile NA, Korones DN, Okunieff P, Walter KA. Primary spinal cord glioma: a Surveillance, Epidemiology, and End Results database study. J Neurooncol. 2010 May; 98(1):83-92.
    View in: PubMed
  • Biswas T, Okunieff P, Schell MC, Smudzin T, Pilcher WH, Bakos RS, Vates GE, Walter KA, Wensel A, Korones DN, Milano MT. Stereotactic radiosurgery for glioblastoma: retrospective analysis. Radiat Oncol. 2009; 4:11.
    View in: PubMed
  • Mentrikoski M, Johnson MD, Korones DN, Scott GA. Glioblastoma multiforme in skin: a report of 2 cases and review of the literature. Am J Dermatopathol. 2008 Aug; 30(4):381-4.
    View in: PubMed
  • Korones DN, Fisher PG, Kretschmar C, Zhou T, Chen Z, Kepner J, Freeman C. Treatment of children with diffuse intrinsic brain stem glioma with radiotherapy, vincristine and oral VP-16: a Children's Oncology Group phase II study. Pediatr Blood Cancer. 2008 Feb; 50(2):227-30.
    View in: PubMed
  • Korones DN. Pediatric palliative care. Pediatr Rev. 2007 Aug; 28(8):e46-56.
    View in: PubMed
  • Korones DN. Treatment of newly diagnosed diffuse brain stem gliomas in children: in search of the holy grail. Expert Rev Anticancer Ther. 2007 May; 7(5):663-74.
    View in: PubMed
  • Braeuninger S, Schneider-Stock R, Kirches E, Powers JM, Korones DN, Mawrin C. Evaluation of molecular genetic alterations associated with tumor progression in a case of gliomatosis cerebri. J Neurooncol. 2007 Mar; 82(1):23-7.
    View in: PubMed
  • Korones DN, Smith A, Foreman N, Bouffet E. Temozolomide and oral VP-16 for children and young adults with recurrent or treatment-induced malignant gliomas. Pediatr Blood Cancer. 2006 Jul; 47(1):37-41.
    View in: PubMed
  • Meyers SP, Khademian ZP, Biegel JA, Chuang SH, Korones DN, Zimmerman RA. Primary intracranial atypical teratoid/rhabdoid tumors of infancy and childhood: MRI features and patient outcomes. AJNR Am J Neuroradiol. 2006 May; 27(5):962-71.
    View in: PubMed
  • Greenberg ML, Fisher PG, Freeman C, Korones DN, Bernstein M, Friedman H, Blaney S, Hershon L, Zhou T, Chen Z, Kretschmar C. Etoposide, vincristine, and cyclosporin A with standard-dose radiation therapy in newly diagnosed diffuse intrinsic brainstem gliomas: a pediatric oncology group phase I study. Pediatr Blood Cancer. 2005 Oct 15; 45(5):644-8.
    View in: PubMed
  • Korones DN. Is routine chest radiography necessary for the initial evaluation of fever in neutropenic children with cancer? Pediatr Blood Cancer. 2004 Dec; 43(7):715-7.
    View in: PubMed
  • Meyers SP, Khademian ZP, Chuang SH, Pollack IF, Korones DN, Zimmerman RA. Choroid plexus carcinomas in children: MRI features and patient outcomes. Neuroradiology. 2004 Sep; 46(9):770-80.
    View in: PubMed
  • Drugas GT, Boulanger B, Korones DN, Katzman PJ, Koniaris LG. Desmoplastic small round cell tumor. Pediatr Blood Cancer. 2004 May; 42(5):489-92.
    View in: PubMed
  • Sweeney DA, Caserta MT, Korones DN, Casadevall A, Goldman DL. A ten-year-old boy with a pulmonary nodule secondary to Cryptococcus neoformans: case report and review of the literature. Pediatr Infect Dis J. 2003 Dec; 22(12):1089-93.
    View in: PubMed
  • Korones DN. Taking time. J Clin Oncol. 2003 Sep 1; 21(17):3366-7.
    View in: PubMed
  • Korones DN, Benita-Weiss M, Coyle TE, Mechtler L, Bushunow P, Evans B, Reardon DA, Quinn JA, Friedman H. Phase I study of temozolomide and escalating doses of oral etoposide for adults with recurrent malignant glioma. Cancer. 2003 Apr 15; 97(8):1963-8.
    View in: PubMed
  • Korones DN, Padowski J, Factor BA, Constine LS. Do children with optic pathway tumors have an increased frequency of other central nervous system tumors? Neuro Oncol. 2003 Apr; 5(2):116-20.
    View in: PubMed
  • Fisher PG, Kadan-Lottick NS, Korones DN. Intrathecal thiotepa: reappraisal of an established therapy. J Pediatr Hematol Oncol. 2002 May; 24(4):274-8.
    View in: PubMed
  • Bruckner LB, Korones DN, Karnauchow T, Hardy DJ, Gigliotti F. High incidence of penicillin resistance among alpha-hemolytic streptococci isolated from the blood of children with cancer. J Pediatr. 2002 Jan; 140(1):20-6.
    View in: PubMed
  • Rios JA, Korones DN, Heal JM, Blumberg N. WBC-reduced blood transfusions and clinical outcome in children with acute lymphoid leukemia. Transfusion. 2001 Jul; 41(7):873-7.
    View in: PubMed
  • Horan J, Korones D. Intensive chemotherapy and bone marrow transplantation for children with acute myeloid leukemia. Blood. 2001 Jun 1; 97(11):3672-3; author reply 3674-5.
    View in: PubMed
  • Korones DN, Butterfield R, Meyers SP, Constine LS. The role of surveillance magnetic resonance imaging (MRI) scanning in detecting recurrent brain tumors in asymptomatic children. J Neurooncol. 2001 May; 53(1):33-8.
    View in: PubMed
  • Korones DN, Brown MR, Palis J. "Liver function tests" are not always tests of liver function. Am J Hematol. 2001 Jan; 66(1):46-8.
    View in: PubMed
  • Meyers SP, Wildenhain SL, Chang JK, Bourekas EC, Beattie PF, Korones DN, Davis D, Pollack IF, Zimmerman RA. Postoperative evaluation for disseminated medulloblastoma involving the spine: contrast-enhanced MR findings, CSF cytologic analysis, timing of disease occurrence, and patient outcomes. AJNR Am J Neuroradiol. 2000 Oct; 21(9):1757-65.
    View in: PubMed
  • Korones DN, Fisher PG, Cohen KJ, Dubowy RL. No responses to oral etoposide in 15 patients with recurrent brain tumors. Med Pediatr Oncol. 2000 Jul; 35(1):80-2.
    View in: PubMed
  • Korones DN. A piece of my mind. Saying good-bye. JAMA. 1999 May 19; 281(19):1778.
    View in: PubMed
  • Korones DN, Meyers SP, Rubio A, Torres C, Constine LS. A 4-year-old girl with a ventriculoperitoneal shunt metastasis of a central nervous system atypical teratoid/rhabdoid tumor. Med Pediatr Oncol. 1999 May; 32(5):389-91.
    View in: PubMed
  • Robbins J, Cromwell P, Korones DN. Swimming and central venous catheter-related infections in the child with cancer. J Pediatr Oncol Nurs. 1999 Jan; 16(1):51-6.
    View in: PubMed
  • Moghrabi A, Friedman HS, Ashley DM, Bottom KS, Kerby T, Stewart E, Bruggers C, Provenzale JM, Champagne M, Hershon L, Watral M, Ryan J, Rasheed K, Lovell S, Korones D, Fuchs H, George T, McLendon RE, Friedman AH, Buckley E, Longee DC. Phase II study of carboplatin (CBDCA) in progressive low-grade gliomas. Neurosurg Focus. 1998 Apr 15; 4(4):e3.
    View in: PubMed
  • Mullins KJ, Rubio A, Myers SP, Korones DN, Pilcher WH. Malignant ependymomas in a patient with Turcot's syndrome: case report and management guidelines. Surg Neurol. 1998 Mar; 49(3):290-4.
    View in: PubMed
  • Korones DN, Hussong MR, Gullace MA. Routine chest radiography of children with cancer hospitalized for fever and neutropenia: is it really necessary? Cancer. 1997 Sep 15; 80(6):1160-4.
    View in: PubMed
  • Weinberg GA, Gigliotti F, Stroncek DF, Eiber G, Kassmann B, Murante B, Korones DN. Lack of relation of granulocyte antibodies (antineutrophil antibodies) to neutropenia in children with human immunodeficiency virus infection. Pediatr Infect Dis J. 1997 Sep; 16(9):881-4.
    View in: PubMed
  • Torres CF, Korones DN, Pilcher W. Multiple ependymomas in a patient with Turcot's syndrome. Med Pediatr Oncol. 1997 Jan; 28(1):59-61.
    View in: PubMed
  • Torres CF, Korones DN, Powers JM, Vadasz AG. Primary leptomeningeal histiocytic lymphoma in a young child. Med Pediatr Oncol. 1996 Dec; 27(6):547-50.
    View in: PubMed
  • Korones DN. High-dose oral dexamethasone therapy in idiopathic thrombocytopenic purpura. J Pediatr. 1996 Nov; 129(5):772-3.
    View in: PubMed
  • Korones DN, Buzzard CJ, Asselin BL, Harris JP. Right atrial thrombi in children with cancer and indwelling catheters. J Pediatr. 1996 Jun; 128(6):841-6.
    View in: PubMed
  • Gilmore MM, Stroncek DF, Korones DN. Treatment of alloimmune neonatal neutropenia with granulocyte colony-stimulating factor. J Pediatr. 1994 Dec; 125(6 Pt 1):948-51.
    View in: PubMed
  • Korones DN, Shapiro ED. Occult pneumococcal bacteremia: what happens to the child who appears well at reevaluation? Pediatr Infect Dis J. 1994 May; 13(5):382-6.
    View in: PubMed
  • Korones DN, Marshall GS, Shapiro ED. Outcome of children with occult bacteremia caused by Haemophilus influenzae type b. Pediatr Infect Dis J. 1992 Jul; 11(7):516-20.
    View in: PubMed
  • White CW, Wolf SJ, Korones DN, Sondheimer HM, Tosi MF, Yu A. Treatment of childhood angiomatous diseases with recombinant interferon alfa-2a. J Pediatr. 1991 Jan; 118(1):59-66.
    View in: PubMed
  • Iyer J, Korones DN, Ikegaki N, Kennett RH, Frantz CN. Regulation of N-myc gene expression in human neuroblastoma. Prog Clin Biol Res. 1991; 366:55-64.
    View in: PubMed
  • Anderson PW, Pichichero ME, Stein EC, Porcelli S, Betts RF, Connuck DM, Korones D, Insel RA, Zahradnik JM, Eby R. Effect of oligosaccharide chain length, exposed terminal group, and hapten loading on the antibody response of human adults and infants to vaccines consisting of Haemophilus influenzae type b capsular antigen unterminally coupled to the diphtheria protein CRM197. J Immunol. 1989 Apr 1; 142(7):2464-8.
    View in: PubMed
  • Korones D, Pearson HA. Normal erythrocyte osmotic fragility in hereditary spherocytosis. J Pediatr. 1989 Feb; 114(2):264-6.
    View in: PubMed
  • Kang ES, Capaci MT, Korones DN, Tekade N. Liver coenzyme A ester content: comparison between Reye's syndrome and control subjects. Clin Sci (Lond). 1982 Nov; 63(5):455-60.
    View in: PubMed

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