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Mary Caserta

TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentPediatrics
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 690
Rochester NY 14642
 
 Awards And Honors
      Recipient, Maimonides Medical Society Award for Excellence in Basic Sciences
1997 - 1998Pediatric Morning Report Teaching Award
1999 - 2002Gilbert B. Forbes Dean's Teaching Scholar Award
2002 - 2003Outstanding Hospital Faculty Teaching Award
2003 - 2004Outstanding Hospital Faculty Teaching Award
2004     Best Doctors in America in Pediatric Infectious Diseases
2005     Best Doctors in America in Pediatric Infectious Diseases
2006     Medicine & Pediatrics Award for Teaching Excellence
2007     Best Doctors in American in Pediatric Infectious Diseases
2008     Best Doctors in America in Pediatric Infectious Diseases
2009     Best Doctors in America in Pediatric Infectious Diseases
2010     Ruth Lawrence Academic Faculty Service Award - Research
 
 Overview
Dr. Caserta's research interest are:

1) Epidemiology and clinical consequences of infection with human herpesvirus-6, herpesvirus-7 in children with special emphasis on epidemiology and pathogenesis

2) Effects of psychosocial factors on susceptibility to infectious diseases

The epidemiology and viral pathogenesis of human herpesvirus 6 (HHV6) is the focus of several ongoing basic research projects in the laboratory. One aspect of this work is the study of immune responses in children with latent and reactivated HHV6 infection. Previous experiments in the lab have shown that all children become infected with HHV6 during infancy or early childhood and that the virus remains latent in the peripheral blood mononuclear cells. Reactivation occurs in a small percentage of normal children and we are examining markers of immune function associated with reactivation, as well as possible outcomes on health in several populations. In addition, studies of the transmission of HHV6 are being pursued.

 
 Selected Publications
List All   |   Timeline
  1. Kainth MK, Fisher SG, Fernandez D, Luque A, Hall CB, Hoang AT, Lashkari A, Peck A, Hasan L, Caserta MT. Understanding the association between chromosomally integrated human herpesvirus 6 and HIV disease: a cross-sectional study. F1000Res. 2013; 2:269.
    View in: PubMed
  2. O'Connor TG, Winter MA, Hunn J, Carnahan J, Pressman EK, Glover V, Robertson-Blackmore E, Moynihan JA, Lee FE, Caserta MT. Prenatal maternal anxiety predicts reduced adaptive immunity in infants. Brain Behav Immun. 2013 Aug; 32:21-8.
    View in: PubMed
  3. Kimberlin DW, Acosta EP, Prichard MN, Sánchez PJ, Ampofo K, Lang D, Ashouri N, Vanchiere JA, Abzug MJ, Abughali N, Caserta MT, Englund JA, Sood SK, Spigarelli MG, Bradley JS, Lew J, Michaels MG, Wan W, Cloud G, Jester P, Lakeman FD, Whitley RJ. Oseltamivir pharmacokinetics, dosing, and resistance among children aged <2 years with influenza. J Infect Dis. 2013 Mar; 207(5):709-20.
    View in: PubMed
  4. Pellett PE, Ablashi DV, Ambros PF, Agut H, Caserta MT, Descamps V, Flamand L, Gautheret-Dejean A, Hall CB, Kamble RT, Kuehl U, Lassner D, Lautenschlager I, Loomis KS, Luppi M, Lusso P, Medveczky PG, Montoya JG, Mori Y, Ogata M, Pritchett JC, Rogez S, Seto E, Ward KN, Yoshikawa T, Razonable RR. Chromosomally integrated human herpesvirus 6: questions and answers. Rev Med Virol. 2012 May; 22(3):144-55.
    View in: PubMed
  5. Caserta MT, Wyman PA, Wang H, Moynihan J, O'Connor TG. Associations among depression, perceived self-efficacy, and immune function and health in preadolescent children. Dev Psychopathol. 2011 Nov; 23(4):1139-47.
    View in: PubMed
  6. Kainth MK, Caserta MT. Molecular diagnostic tests for human herpesvirus 6. Pediatr Infect Dis J. 2011 Jul; 30(7):604-5.
    View in: PubMed
  7. Caserta MT, Dewhurst S. Dazed and confused by HHV-6. Blood. 2011 May 12; 117(19):5016-8.
    View in: PubMed
  8. Caserta MT, Hall CB, Schnabel K, Lofthus G, Marino A, Shelley L, Yoo C, Carnahan J, Anderson L, Wang H. Diagnostic assays for active infection with human herpesvirus 6 (HHV-6). J Clin Virol. 2010 May; 48(1):55-7.
    View in: PubMed
  9. Hall CB, Caserta MT, Schnabel KC, Shelley LM, Carnahan JA, Marino AS, Yoo C, Lofthus GK. Transplacental congenital human herpesvirus 6 infection caused by maternal chromosomally integrated virus. J Infect Dis. 2010 Feb 15; 201(4):505-7.
    View in: PubMed
  10. Hall CB, Caserta MT, Schnabel K, Shelley LM, Marino AS, Carnahan JA, Yoo C, Lofthus GK, McDermott MP. Chromosomal integration of human herpesvirus 6 is the major mode of congenital human herpesvirus 6 infection. Pediatrics. 2008 Sep; 122(3):513-20.
    View in: PubMed
  11. Thingvoll ES, Guillet R, Caserta M, Dicenzo R. Observational trial of a 48-hour gentamicin dosing regimen derived from Monte Carlo simulations in infants born at less than 28 weeks' gestation. J Pediatr. 2008 Oct; 153(4):530-4.
    View in: PubMed
  12. Caserta MT, O'Connor TG, Wyman PA, Wang H, Moynihan J, Cross W, Tu X, Jin X. The associations between psychosocial stress and the frequency of illness, and innate and adaptive immune function in children. Brain Behav Immun. 2008 Aug; 22(6):933-40.
    View in: PubMed
  13. Caserta MT, Hall CB, Schnabel K, Lofthus G, McDermott MP. Human herpesvirus (HHV)-6 and HHV-7 infections in pregnant women. J Infect Dis. 2007 Nov 1; 196(9):1296-303.
    View in: PubMed
  14. Cholette JM, Caserta M, Hardy D, Connolly HV. Outcome of pulmonary function in Lemierre's disease-associated acute respiratory distress syndrome. Pediatr Pulmonol. 2007 Apr; 42(4):389-92.
    View in: PubMed
  15. Wyman PA, Moynihan J, Eberly S, Cox C, Cross W, Jin X, Caserta MT. Association of family stress with natural killer cell activity and the frequency of illnesses in children. Arch Pediatr Adolesc Med. 2007 Mar; 161(3):228-34.
    View in: PubMed
  16. Hall CB, Caserta MT, Schnabel KC, McDermott MP, Lofthus GK, Carnahan JA, Gilbert LM, Dewhurst S. Characteristics and acquisition of human herpesvirus (HHV) 7 infections in relation to infection with HHV-6. J Infect Dis. 2006 Apr 15; 193(8):1063-9.
    View in: PubMed
  17. Oberholzer CM, Caserta MT. Antimicrobial update: Daptomycin. Pediatr Infect Dis J. 2005 Oct; 24(10):919-20.
    View in: PubMed
  18. Hall CB, Caserta MT, Schnabel KC, Boettrich C, McDermott MP, Lofthus GK, Carnahan JA, Dewhurst S. Congenital infections with human herpesvirus 6 (HHV6) and human herpesvirus 7 (HHV7). J Pediatr. 2004 Oct; 145(4):472-7.
    View in: PubMed
  19. Caserta MT, McDermott MP, Dewhurst S, Schnabel K, Carnahan JA, Gilbert L, Lathan G, Lofthus GK, Hall CB. Human herpesvirus 6 (HHV6) DNA persistence and reactivation in healthy children. J Pediatr. 2004 Oct; 145(4):478-84.
    View in: PubMed
  20. Sweeney DA, Caserta MT, Korones DN, Casadevall A, Goldman DL. A ten-year-old boy with a pulmonary nodule secondary to Cryptococcus neoformans: case report and review of the literature. Pediatr Infect Dis J. 2003 Dec; 22(12):1089-93.
    View in: PubMed
  21. Caserta MT, Mock DJ, Dewhurst S. Human herpesvirus 6. Clin Infect Dis. 2001 Sep 15; 33(6):829-33.
    View in: PubMed
  22. Caserta MT, Hall CB. Antiviral agents for influenza. Pediatr Ann. 2000 Nov; 29(11):704-11.
    View in: PubMed
  23. Norton RA, Caserta MT, Hall CB, Schnabel K, Hocknell P, Dewhurst S. Detection of human herpesvirus 6 by reverse transcription-PCR. J Clin Microbiol. 1999 Nov; 37(11):3672-5.
    View in: PubMed
  24. Caserta MT, Hall CB. A practitioner's guide to human herpesvirus-6 (HHV-6) and human herpesvirus-7 (HHV-7). AIDS Patient Care STDS. 1998 Nov; 12(11):833-42.
    View in: PubMed
  25. Caserta MT, Hall CB, Schnabel K, Long CE, D'Heron N. Primary human herpesvirus 7 infection: a comparison of human herpesvirus 7 and human herpesvirus 6 infections in children. J Pediatr. 1998 Sep; 133(3):386-9.
    View in: PubMed
  26. Lee LH, Caserta MT. Malaria: update on treatment. Pediatr Infect Dis J. 1998 Apr; 17(4):342-3.
    View in: PubMed
  27. Hall CB, Caserta MT, Schnabel KC, Long C, Epstein LG, Insel RA, Dewhurst S. Persistence of human herpesvirus 6 according to site and variant: possible greater neurotropism of variant A. Clin Infect Dis. 1998 Jan; 26(1):132-7.
    View in: PubMed
  28. Caserta MT, Hall CB, Schnabel K, McIntyre K, Long C, Costanzo M, Dewhurst S, Insel R, Epstein LG. Neuroinvasion and persistence of human herpesvirus 6 in children. J Infect Dis. 1994 Dec; 170(6):1586-9.
    View in: PubMed
  29. Hall CB, Long CE, Schnabel KC, Caserta MT, McIntyre KM, Costanzo MA, Knott A, Dewhurst S, Insel RA, Epstein LG. Human herpesvirus-6 infection in children. A prospective study of complications and reactivation. N Engl J Med. 1994 Aug 18; 331(7):432-8.
    View in: PubMed
  30. Caserta MT, Hall CB. Human herpesvirus-6. Annu Rev Med. 1993; 44:377-83.
    View in: PubMed
  31. Sills RH, Caserta MT, Landaw SA. Decreased erythrocyte deformability in the anemia of bacterial meningitis. J Pediatr. 1982 Sep; 101(3):395-8.
    View in: PubMed

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