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John Langfitt

TitleAssociate Professor
InstitutionSchool of Medicine and Dentistry
DepartmentNeurology
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 673
Rochester NY 14642
 
 Awards And Honors
1981     Graduated cum laude
 
 Overview
Dr. Langfitt's research focusses on the cognitive, psychiatric, quality-of-life and economic effects of epilepsy and its treatments. His expertise lies in design and implementation of clinical trials and other research designs, with a specific focus on outcomes assessment.

 
 Selected Publications
List All   |   Timeline
  1. Hamid H, Blackmon K, Cong X, Dziura J, Atlas LY, Vickrey BG, Berg AT, Bazil CW, Langfitt JT, Walczak TS, Sperling MR, Shinnar S, Devinsky O. Mood, anxiety, and incomplete seizure control affect quality of life after epilepsy surgery. Neurology. 2014 Mar 11; 82(10):887-94.
    View in: PubMed
  2. Brown FC, Westerveld M, Langfitt JT, Hamberger M, Hamid H, Shinnar S, Sperling MR, Devinsky O, Barr W, Tracy J, Masur D, Bazil CW, Spencer SS. Influence of anxiety on memory performance in temporal lobe epilepsy. Epilepsy Behav. 2014 Feb; 31:19-24.
    View in: PubMed
  3. Langfitt JT, Mathern GW. Web-based eight-question tool to determine epilepsy surgery evaluation: the future is here. Neurology. 2012 Sep 11; 79(11):1074-5.
    View in: PubMed
  4. Tivarus ME, Starling SJ, Newport EL, Langfitt JT. Homotopic language reorganization in the right hemisphere after early left hemisphere injury. Brain Lang. 2012 Oct; 123(1):1-10.
    View in: PubMed
  5. Engel J, McDermott MP, Wiebe S, Langfitt JT, Stern JM, Dewar S, Sperling MR, Gardiner I, Erba G, Fried I, Jacobs M, Vinters HV, Mintzer S, Kieburtz K. Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. JAMA. 2012 Mar 7; 307(9):922-30.
    View in: PubMed
  6. Hamid H, Liu H, Cong X, Devinsky O, Berg AT, Vickrey BG, Sperling MR, Shinnar S, Langfitt JT, Walczak TS, Barr WB, Dziura J, Bazil CW, Spencer SS. Long-term association between seizure outcome and depression after resective epilepsy surgery. Neurology. 2011 Nov 29; 77(22):1972-6.
    View in: PubMed
  7. Hamid H, Devinsky O, Vickrey BG, Berg AT, Bazil CW, Langfitt JT, Walczak TS, Sperling MR, Shinnar S, Spencer SS. Suicide outcomes after resective epilepsy surgery. Epilepsy Behav. 2011 Mar; 20(3):462-4.
    View in: PubMed
  8. Sharan A, Ooi YC, Langfitt J, Sperling MR. Intracarotid amobarbital procedure for epilepsy surgery. Epilepsy Behav. 2011 Feb; 20(2):209-13.
    View in: PubMed
  9. Langfitt J, Watson W. "Seizures" or "attacks": a follow-up. Neurology. 2010 Dec 7; 75(23):2056-7.
    View in: PubMed
  10. Hermann B, Langfitt J. Forgetting to remember in epilepsy: a family affair? Neurology. 2010 Dec 14; 75(24):2144-55.
    View in: PubMed
  11. Engel J, McDermott MP, Wiebe S, Langfitt JT, Erba G, Gardiner I, Stern J, Dewar S, Sperling MR, Jacobs M, Kieburtz K. Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy. Epilepsia. 2010 Oct; 51(10):1978-86.
    View in: PubMed
  12. Binder JR, Gross WL, Allendorfer JB, Bonilha L, Chapin J, Edwards JC, Grabowski TJ, Langfitt JT, Loring DW, Lowe MJ, Koenig K, Morgan PS, Ojemann JG, Rorden C, Szaflarski JP, Tivarus ME, Weaver KE. Mapping anterior temporal lobe language areas with fMRI: a multicenter normative study. Neuroimage. 2011 Jan 15; 54(2):1465-75.
    View in: PubMed
  13. Berg AT, Langfitt JT, Testa FM, Levy SR, DiMario F, Westerveld M, Kulas J. Residual cognitive effects of uncomplicated idiopathic and cryptogenic epilepsy. Epilepsy Behav. 2008 Nov; 13(4):614-9.
    View in: PubMed
  14. Langfitt JT, Wiebe S. Early surgical treatment for epilepsy. Curr Opin Neurol. 2008 Apr; 21(2):179-83.
    View in: PubMed
  15. Berg AT, Langfitt JT, Testa FM, Levy SR, DiMario F, Westerveld M, Kulas J. Global cognitive function in children with epilepsy: a community-based study. Epilepsia. 2008 Apr; 49(4):608-14.
    View in: PubMed
  16. Langfitt JT. Do we know quality epilepsy care when we see it? Neurology. 2007 Nov 20; 69(21):1968-9.
    View in: PubMed
  17. Spencer SS, Berg AT, Vickrey BG, Sperling MR, Bazil CW, Haut S, Langfitt JT, Walczak TS, Devinsky O. Health-related quality of life over time since resective epilepsy surgery. Ann Neurol. 2007 Oct; 62(4):327-34.
    View in: PubMed
  18. Chin PS, Berg AT, Spencer SS, Sperling MR, Haut SR, Langfitt JT, Bazil CW, Walczak TS, Pacia SV, Vickrey BG. Employment outcomes following resective epilepsy surgery. Epilepsia. 2007 Dec; 48(12):2253-7.
    View in: PubMed
  19. Langfitt JT, Westerveld M, Hamberger MJ, Walczak TS, Cicchetti DV, Berg AT, Vickrey BG, Barr WB, Sperling MR, Masur D, Spencer SS. Worsening of quality of life after epilepsy surgery: effect of seizures and memory decline. Neurology. 2007 Jun 5; 68(23):1988-94.
    View in: PubMed
  20. Langfitt JT, Holloway RG, McDermott MP, Messing S, Sarosky K, Berg AT, Spencer SS, Vickrey BG, Sperling MR, Bazil CW, Shinnar S. Health care costs decline after successful epilepsy surgery. Neurology. 2007 Apr 17; 68(16):1290-8.
    View in: PubMed
  21. Begley CE, Baker GA, Beghi E, Butler J, Chisholm D, Langfitt JT, Levy P, Pachlatko C, Wiebe S, Donaldson KL. Cross-country measures for monitoring epilepsy care. Epilepsia. 2007 May; 48(5):990-1001.
    View in: PubMed
  22. Berg AT, Langfitt JT, Spencer SS, Vickrey BG. Stopping antiepileptic drugs after epilepsy surgery: a survey of U.S. epilepsy center neurologists. Epilepsy Behav. 2007 Mar; 10(2):219-22.
    View in: PubMed
  23. Theodore WH, Spencer SS, Wiebe S, Langfitt JT, Ali A, Shafer PO, Berg AT, Vickrey BG. Epilepsy in North America: a report prepared under the auspices of the global campaign against epilepsy, the International Bureau for Epilepsy, the International League Against Epilepsy, and the World Health Organization. Epilepsia. 2006 Oct; 47(10):1700-22.
    View in: PubMed
  24. Chin PS, Berg AT, Spencer SS, Lee ML, Shinnar S, Sperling MR, Langfitt JT, Walczak TS, Pacia SV, Bazil CW, Vassar S, Vickrey BG. Patient-perceived impact of resective epilepsy surgery. Neurology. 2006 Jun 27; 66(12):1882-7.
    View in: PubMed
  25. Langfitt JT, Vickrey BG, McDermott MP, Messing S, Berg AT, Spencer SS, Sperling MR, Bazil CW, Shinnar S. Validity and responsiveness of generic preference-based HRQOL instruments in chronic epilepsy. Qual Life Res. 2006 Jun; 15(5):899-914.
    View in: PubMed
  26. Berg AT, Vickrey BG, Langfitt JT, Sperling MR, Shinnar S, Bazil C, Walczak T, Spencer SS. Reduction of AEDs in postsurgical patients who attain remission. Epilepsia. 2006 Jan; 47(1):64-71.
    View in: PubMed
  27. Devinsky O, Barr WB, Vickrey BG, Berg AT, Bazil CW, Pacia SV, Langfitt JT, Walczak TS, Sperling MR, Shinnar S, Spencer SS. Changes in depression and anxiety after resective surgery for epilepsy. Neurology. 2005 Dec 13; 65(11):1744-9.
    View in: PubMed
  28. Spencer SS, Berg AT, Vickrey BG, Sperling MR, Bazil CW, Shinnar S, Langfitt JT, Walczak TS, Pacia SV. Predicting long-term seizure outcome after resective epilepsy surgery: the multicenter study. Neurology. 2005 Sep 27; 65(6):912-8.
    View in: PubMed
  29. Janzen L, Sherman E, Langfitt J, Berg M, Connolly M. Preserved episodic memory in subcortical band heterotopia. Epilepsia. 2004 May; 45(5):555-8.
    View in: PubMed
  30. Langfitt J, Meador K. Want to improve epilepsy care?: Ask the patient. Neurology. 2004 Jan 13; 62(1):6-7.
    View in: PubMed
  31. Spencer SS, Berg AT, Vickrey BG, Sperling MR, Bazil CW, Shinnar S, Langfitt JT, Walczak TS, Pacia SV, Ebrahimi N, Frobish D. Initial outcomes in the Multicenter Study of Epilepsy Surgery. Neurology. 2003 Dec 23; 61(12):1680-5.
    View in: PubMed
  32. Berg AT, Vickrey BG, Langfitt JT, Sperling MR, Walczak TS, Shinnar S, Bazil CW, Pacia SV, Spencer SS. The multicenter study of epilepsy surgery: recruitment and selection for surgery. Epilepsia. 2003 Nov; 44(11):1425-33.
    View in: PubMed
  33. Stroup E, Langfitt J, Berg M, McDermott M, Pilcher W, Como P. Predicting verbal memory decline following anterior temporal lobectomy (ATL). Neurology. 2003 Apr 22; 60(8):1266-73.
    View in: PubMed
  34. Berg AT, Langfitt J, Shinnar S, Vickrey BG, Sperling MR, Walczak T, Bazil C, Pacia SV, Spencer SS. How long does it take for partial epilepsy to become intractable? Neurology. 2003 Jan 28; 60(2):186-90.
    View in: PubMed
  35. Haut SR, Berg AT, Shinnar S, Cohen HW, Bazil CW, Sperling MR, Langfitt JT, Pacia SV, Walczak TS, Spencer SS. Interrater reliability among epilepsy centers: multicenter study of epilepsy surgery. Epilepsia. 2002 Nov; 43(11):1396-401.
    View in: PubMed
  36. Begley CE, Beghi E, Beran RG, Heaney D, Langfitt JT, Pachlatko C, Silfvenius H, Sperling MR, Wiebe S. ILAE Commission on the Burden of Epilepsy, Subcommission on the Economic Burden of Epilepsy: Final report 1998-2001. Epilepsia. 2002 Jun; 43(6):668-73.
    View in: PubMed
  37. Langfitt J, Wiebe S. Cost-effectiveness of epilepsy therapy: how should treatment effects be measured? Epilepsia. 2002; 43 Suppl 4:17-24.
    View in: PubMed
  38. Vickrey BG, Berg AT, Sperling MR, Shinnar S, Langfitt JT, Bazil CW, Walczak TS, Pacia S, Kim S, Spencer SS. Relationships between seizure severity and health-related quality of life in refractory localization-related epilepsy. Epilepsia. 2000 Jun; 41(6):760-4.
    View in: PubMed
  39. Berg AT, Vickrey BG, Sperling MR, Langfitt JT, Bazil CW, Shinnar S, Walczak TS, Pacia S, Spencer SS. Driving in adults with refractory localization-related epilepsy. Multi-Center Study of Epilepsy Surgery. Neurology. 2000 Feb 8; 54(3):625-30.
    View in: PubMed
  40. Langfitt JT. Cost evaluations in epilepsy: an update. Epilepsia. 2000; 41 Suppl 2:S62-8.
    View in: PubMed
  41. Langfitt JT, Wood BL, Brand KL, Brand J, Erba G. Family interactions as targets for intervention to improve social adjustment after epilepsy surgery. Epilepsia. 1999 Jun; 40(6):735-44.
    View in: PubMed
  42. Langfitt JT. Cost-effectiveness of anterotemporal lobectomy in medically intractable complex partial epilepsy. Epilepsia. 1997 Feb; 38(2):154-63.
    View in: PubMed
  43. Pilcher WH, Langfitt J. Analysis of outcome: temporal lobe resection. Clin Neurosurg. 1997; 44:401-21.
    View in: PubMed
  44. Langfitt JT, Rausch R. Word-finding deficits persist after left anterotemporal lobectomy. Arch Neurol. 1996 Jan; 53(1):72-6.
    View in: PubMed
  45. Langfitt JT. Comparison of the psychometric characteristics of three quality of life measures in intractable epilepsy. Qual Life Res. 1995 Apr; 4(2):101-14.
    View in: PubMed
  46. Ettlin TM, Beckson M, Benson DF, Langfitt JT, Amos EC, Pineda GS. Prosopagnosia: a bihemispheric disorder. Cortex. 1992 Mar; 28(1):129-34.
    View in: PubMed

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