URMC Research Network - Robert Griggs

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Robert Griggs

Title	Professor
Institution	School of Medicine and Dentistry
Department	Neurology
Address	University of Rochester Medical Center School of Medicine and Dentistry 601 Elmwood Ave, Box CU 420669 Rochester NY 14642

Other Positions


Title	Professor
Institution	School of Medicine and Dentistry
Department	Pediatrics
Title	Professor
Institution	School of Medicine and Dentistry
Department	Pathology and Laboratory Medicine

Title	Professor
Institution	School of Medicine and Dentistry
Department	Medicine

Awards And Honors

1970	-	1971	Special Research Fellowship, National Institute of Neurological Diseases and Stroke; Bethesda, Maryland
1971	-	1974	American College of Physicians Research and Teaching Scholarship
1972			Fellow, Neuroscience Research Program; Boulder, Colorado
1980	-	1981	Dr. Henry C. and Bertha H. Buswell Distinguished Service Fellow, School of Medicine, University of Rochester
1981	-	1982	Senior Fellow, Fogarty International Center, National Institutes of Health
1984	-	1985	Mentor Award, University of Rochester
1984			Albert H. Douglas, M.D. Memorial Award for Excellence in Clinical Teaching. Medical Society of the State of New York
1990			Visiting Fellow, Department of Biochemistry, University of Leicester (Training in molecular biology in the laboratory of David Critchley, Ph.D.)
1990			Burroughs Wellcome Traveling Research Fellowship, Leicester, U.K. (Laboratory of D. Critchley, Ph.D.)
1998			Rochester Academy of Medicine Award of Merit, Rochester, New York
1998			Elected, Institute of Medicine of the National Academy of Sciences
2000			Honorary Member, French Neurological Society
2003			Woodward/White, Inc., The Best Doctors in America (listed since 1981)
2007			Amicus 8, Faculty of Medicine, Jagiellonian University, Krakow, Poland

Overview

Dr. Griggs is Professor of Neurology, Medicine, Pathology and Laboratory Medicine, Pediatrics Center for Human Experimental Therapeutics at the University of Rochester School of Medicine and Dentistry. He served as Chair of the Department of Neurology and Neurologist-in-Chief at Strong Memorial Hospital 1986-2008. He received his BA from the University of Delaware and his M.D. from the University of Pennsylvania. He received training in Internal Medicine at Case Western Reserve University and the University of Rochester where he was Chief Resident in Medicine and Fellow in Immunology. He trained in Neurology at the National Institute of Neurological Disorders and Stroke (NINDS) and the University of Rochester where he was Chief Resident in Neurology.

Dr. Griggs' research interests are focused on developing new treatments for neuromuscular diseases. He has developed treatments for the periodic paralyses, non-dystrophic myotonia, Duchenne muscular dystrophy and inflammatory myopathies. He has directed an NIH-funded (1990-2015) training program in the Experimental Therapeutics of Neurological Disease since 1989.

Since 1998, Dr. Griggs has chaired the Executive Committee of the Muscle Study Group (MSG), an international consortium of investigators focused on developing new treatments for neuromuscular disease. The MSG is supported by grants from the National Institute of Health, Food and Drug Administration, industry, and a number of foundations. Dr. Griggs is currently principal investigator of the NIH-funded studies: "Acetazolamide vs Dichlorphenamide vs Placebo in Periodic Paralysis (HYP HOP), Double-blind Randomized Trial to Optimize Steroid Regimen in Duchenne Muscular Dystrophy (FOR-DMD) – a 40 center, 5 country study, and a 10 center Rare Disease Consortium: Clinical Investigation of Neurological Channelopathies (CINCH) which focuses on periodic paralysis, non-dystrophic myotonia and episodic ataxia.

Selected Publications

Scully MA, Cwik VA, Marshall BC, Ciafaloni E, Wolff JM, Getchius TS, Griggs RC. Can outcomes in Duchenne muscular dystrophy be improved by public reporting of data? Neurology. 2013 Feb 5; 80(6):583-9.

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Statland JM, Bundy BN, Wang Y, Rayan DR, Trivedi JR, Sansone VA, Salajegheh MK, Venance SL, Ciafaloni E, Matthews E, Meola G, Herbelin L, Griggs RC, Barohn RJ, Hanna MG. Mexiletine for symptoms and signs of myotonia in nondystrophic myotonia: a randomized controlled trial. JAMA. 2012 Oct 3; 308(13):1357-65.

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Murphy SM, Puwanant A, Griggs RC. Unintended effects of orphan product designation for rare neurological diseases. Ann Neurol. 2012 Oct; 72(4):481-90.

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Statland JM, Bundy BN, Wang Y, Trivedi JR, Raja Rayan D, Herbelin L, Donlan M, McLin R, Eichinger KJ, Findlater K, Dewar L, Pandya S, Martens WB, Venance SL, Matthews E, Amato AA, Hanna MG, Griggs RC, Barohn RJ. A quantitative measure of handgrip myotonia in non-dystrophic myotonia. Muscle Nerve. 2012 Oct; 46(4):482-9.

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Statland JM, Griggs RC, Augustine EF. Emerging Subspecialties in Neurology: Fellowship in experimental therapeutics of neurologic disease. Neurology. 2012 Sep 25; 79(13):e106-8.

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Hutchins JC, Rydell CM, Griggs RC, Sagsveen M, Bernat JL. American Academy of Neurology policy on pharmaceutical and device industry support. Neurology. 2012 Mar 6; 78(10):750-4.

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Platt D, Griggs RC. Use of acetazolamide in sulfonamide-allergic patients with neurologic channelopathies. Arch Neurol. 2012 Apr; 69(4):527-9.

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Matthews E, Portaro S, Ke Q, Sud R, Haworth A, Davis MB, Griggs RC, Hanna MG. Acetazolamide efficacy in hypokalemic periodic paralysis and the predictive role of genotype. Neurology. 2011 Nov 29; 77(22):1960-4.

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Kyriakides T, Pegoraro E, Hoffman EP, Piva L, Cagnin S, Lanfranchi G, Griggs RC, Nelson SF. SPP1 genotype is a determinant of disease severity in Duchenne muscular dystrophy: Predicting the severity of Duchenne Muscular Dystrophy: Implications For Treatment. Neurology. 2011 Nov 15; 77(20):1858-9.

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Griggs RC. Neurology (1997-2006): "A man's reach must exceed his grasp"--from Andrea del Sarto, Robert Browning. Neurology. 2011 Sep 6; 77(10):928-9.

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Statland JM, Wang Y, Richesson R, Bundy B, Herbelin L, Gomes J, Trivedi J, Venance S, Amato A, Hanna M, Griggs R, Barohn RJ. An interactive voice response diary for patients with non-dystrophic myotonia. Muscle Nerve. 2011 Jul; 44(1):30-5.

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Puwanant A, Evangelisti SM, Griggs RC. Treating the chief complaint: hand rejuvenation for Hirayama disease. Neurology. 2011 Jul 12; 77(2):190-1.

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Kaufmann P, McDermott MP, Darras BT, Finkel R, Kang P, Oskoui M, Constantinescu A, Sproule DM, Foley AR, Yang M, Tawil R, Chung W, Martens B, Montes J, O'Hagen J, Dunaway S, Flickinger JM, Quigley J, Riley S, Glanzman AM, Benton M, Ryan PA, Irvine C, Annis CL, Butler H, Caracciolo J, Montgomery M, Marra J, Koo B, De Vivo DC. Observational study of spinal muscular atrophy type 2 and 3: functional outcomes over 1 year. Arch Neurol. 2011 Jun; 68(6):779-86.

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Amato AA, Griggs RC. Overview of the muscular dystrophies. Handb Clin Neurol. 2011; 101:1-9.

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Griggs RC, Amato AA. Muscular dystrophies. Preface. Handb Clin Neurol. 2011; 101:ix.

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Nelson SF, Griggs RC. Predicting the severity of Duchenne muscular dystrophy: implications for treatment. Neurology. 2011 Jan 18; 76(3):208-9.

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Kaufmann P, Annis C, Griggs RC. The authorship lottery: an impediment to research collaboration? Ann Neurol. 2010 Dec; 68(6):782-6.

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Tomlinson SE, Tan SV, Kullmann DM, Griggs RC, Burke D, Hanna MG, Bostock H. Nerve excitability studies characterize Kv1.1 fast potassium channel dysfunction in patients with episodic ataxia type 1. Brain. 2010 Dec; 133(Pt 12):3530-40.

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Griggs RC. The AAN disciplinary process: indispensable to neurologists. Neurology. 2010 Dec 14; 75(24):2148-9.

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Aartsma-Rus A. The risks of therapeutic misconception and individual patient (n=1) "trials" in rare diseases such as Duchenne dystrophy. Neuromuscul Disord. 2011 Jan; 21(1):13-5.

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Griggs RC, Udd BA. Markesbery disease: autosomal dominant late-onset distal myopathy: from phenotype to ZASP gene identification. Neuromolecular Med. 2011 Mar; 13(1):27-30.

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Griggs RC. Duchenne muscular dystrophy: an important negative trial. Lancet Neurol. 2010 Nov; 9(11):1038-9.

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Montes J, McDermott MP, Martens WB, Dunaway S, Glanzman AM, Riley S, Quigley J, Montgomery MJ, Sproule D, Tawil R, Chung WK, Darras BT, De Vivo DC, Kaufmann P, Finkel RS. Six-Minute Walk Test demonstrates motor fatigue in spinal muscular atrophy. Neurology. 2010 Mar 9; 74(10):833-8.

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Matthews E, Fialho D, Tan SV, Venance SL, Cannon SC, Sternberg D, Fontaine B, Amato AA, Barohn RJ, Griggs RC, Hanna MG. The non-dystrophic myotonias: molecular pathogenesis, diagnosis and treatment. Brain. 2010 Jan; 133(Pt 1):9-22.

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Platt D, Griggs R. Skeletal muscle channelopathies: new insights into the periodic paralyses and nondystrophic myotonias. Curr Opin Neurol. 2009 Oct; 22(5):524-31.

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Mitsumoto J, Dorsey ER, Beck CA, Kieburtz K, Griggs RC. Pivotal studies of orphan drugs approved for neurological diseases. Ann Neurol. 2009 Aug; 66(2):184-90.

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Jackson CE, Gronseth G, Rosenfeld J, Barohn RJ, Dubinsky R, Simpson CB, McVey A, Kittrell PP, King R, Herbelin L. Randomized double-blind study of botulinum toxin type B for sialorrhea in ALS patients. Muscle Nerve. 2009 Feb; 39(2):137-43.

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Griggs RC, Batshaw M, Dunkle M, Gopal-Srivastava R, Kaye E, Krischer J, Nguyen T, Paulus K, Merkel PA. Clinical research for rare disease: opportunities, challenges, and solutions. Mol Genet Metab. 2009 Jan; 96(1):20-6.

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Lochmüller H, Griggs RC. New treatments for neuromuscular disease: optimism and obstacles. Neurotherapeutics. 2008 Oct; 5(4):497-8.

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Cleland JC, Griggs RC. Treatment of neuromuscular channelopathies: current concepts and future prospects. Neurotherapeutics. 2008 Oct; 5(4):607-12.

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Mercuri E, Mayhew A, Muntoni F, Messina S, Straub V, Van Ommen GJ, Voit T, Bertini E, Bushby K. Towards harmonisation of outcome measures for DMD and SMA within TREAT-NMD; report of three expert workshops: TREAT-NMD/ENMC workshop on outcome measures, 12th--13th May 2007, Naarden, The Netherlands; TREAT-NMD workshop on outcome measures in experimental trials for DMD, 30th June--1st July 2007, Naarden, The Netherlands; conjoint Institute of Myology TREAT-NMD meeting on physical activity monitoring in neuromuscular disorders, 11th July 2007, Paris, France. Neuromuscul Disord. 2008 Nov; 18(11):894-903.

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Jen JC, Graves TD, Hess EJ, Hanna MG, Griggs RC, Baloh RW. Primary episodic ataxias: diagnosis, pathogenesis and treatment. Brain. 2007 Oct; 130(Pt 10):2484-93.

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Bushby K, Griggs R. 145th ENMC International Workshop: planning for an International Trial of Steroid Dosage Regimes in DMD (FOR DMD), 22-24th October 2006, Naarden, The Netherlands. Neuromuscul Disord. 2007 May; 17(5):423-8.

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Venance SL, Herr BE, Griggs RC. Challenges in the design and conduct of therapeutic trials in channel disorders. Neurotherapeutics. 2007 Apr; 4(2):199-204.

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Griggs R, Vihola A, Hackman P, Talvinen K, Haravuori H, Faulkner G, Eymard B, Richard I, Selcen D, Engel A, Carpen O, Udd B. Zaspopathy in a large classic late-onset distal myopathy family. Brain. 2007 Jun; 130(Pt 6):1477-84.

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Rose MR, Griggs RC. Inclusion body myositis. Handb Clin Neurol. 2007; 86:255-72.

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Daroff RB, Griggs RC. Retraction of "Preferential degradation of oxidized proteins by the 20S proteasome may be inhibited in aging and in inflammatory neuromuscular diseases". Neurology. 2006 Dec 12; 67(11):2087.

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Moore SA, Shilling CJ, Westra S, Wall C, Wicklund MP, Stolle C, Brown CA, Michele DE, Piccolo F, Winder TL, Stence A, Barresi R, King N, King W, Florence J, Campbell KP, Fenichel GM, Stedman HH, Kissel JT, Griggs RC, Pandya S, Mathews KD, Pestronk A, Serrano C, Darvish D, Mendell JR. Limb-girdle muscular dystrophy in the United States. J Neuropathol Exp Neurol. 2006 Oct; 65(10):995-1003.

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Daroff RB, Griggs RC. Partial retraction of correspondence about "the pentapeptide QYNAD does not block voltage-gated sodium channels". Neurology. 2006 Feb 14; 66(3):456.

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Griggs RC. The current status of treatment for inclusion-body myositis. Neurology. 2006 Jan 24; 66(2 Suppl 1):S30-2.

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Venance SL, Cannon SC, Fialho D, Fontaine B, Hanna MG, Ptacek LJ, Tristani-Firouzi M, Tawil R, Griggs RC. The primary periodic paralyses: diagnosis, pathogenesis and treatment. Brain. 2006 Jan; 129(Pt 1):8-17.

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Griggs RC, Bushby K. Continued need for caution in the diagnosis of Duchenne muscular dystrophy. Neurology. 2005 May 10; 64(9):1498-9.

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Miller TM, Dias da Silva MR, Miller HA, Kwiecinski H, Mendell JR, Tawil R, McManis P, Griggs RC, Angelini C, Servidei S, Petajan J, Dalakas MC, Ranum LP, Fu YH, Ptácek LJ. Correlating phenotype and genotype in the periodic paralyses. Neurology. 2004 Nov 9; 63(9):1647-55.

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Bushby K, Muntoni F, Urtizberea A, Hughes R, Griggs R. Report on the 124th ENMC International Workshop. Treatment of Duchenne muscular dystrophy; defining the gold standards of management in the use of corticosteroids. 2-4 April 2004, Naarden, The Netherlands. Neuromuscul Disord. 2004 Sep; 14(8-9):526-34.

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Randomized pilot trial of high-dose betaINF-1a in patients with inclusion body myositis. Neurology. 2004 Aug 24; 63(4):718-20.

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Griggs RC, Pieper KM. Neurology 2004. Neurology. 2004 Jan 13; 62(1):4-5.

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Amato AA, Griggs RC. Treatment of idiopathic inflammatory myopathies. Curr Opin Neurol. 2003 Oct; 16(5):569-75.

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Amato AA, Griggs RC. Unicorns, dragons, polymyositis, and other mythological beasts. Neurology. 2003 Aug 12; 61(3):288-9.

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Udd B, Bushby K, Nonaka I, Griggs R. 104th European Neuromuscular Centre (ENMC) International Workshop: distal myopathies, 8-10th March 2002 in Naarden, The Netherlands. Neuromuscul Disord. 2002 Nov; 12(9):897-904.

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Tawil R, Griggs RC. Inclusion body myositis. Curr Opin Rheumatol. 2002 Nov; 14(6):653-7.

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Rosenberg RN, Aminoff M, Boller F, Soerensen PS, Griggs RC, Hachinski V, Hallett M, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Author's right to access to all data obtained in their study. J Neurol. 2002 May; 249(5):638-9.

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Griggs RC, Anderson DC. An important first step: a standard curriculum for the neurology clerkship. Neurology. 2002 Mar 26; 58(6):845-6.

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Rosenberg RN, Aminoff M, Boller F, Soerensen PS, Griggs RC, Hachinski V, Hallett M, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Brain. 2002 Mar; 125(Pt 3):i-ii.

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Rosenberg RR, Aminoff M, Boller F, Sørensen PS, Griggs RC, Hallett M, Johnson RT, Hachinski V, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Eur J Neurol. 2002 Mar; 9(2):123-4.

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Rosenberg RN, Aminoff M, Boller F, Sørenson PS, Griggs RC, Hachinski V, Hallett M, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Neurology. 2002 Feb 12; 58(3):347-8.

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Rosenberg RN, Aminoff M, BoIler F, Soerensen PS, Griggs RC, Hachinski V, Hallett M, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, SeIzer ME, Zochodne D. Reporting clinical trials: full access to all the data. J Neurol Neurosurg Psychiatry. 2002 Feb; 72(2):143.

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Rosenberg RN, Aminoff MJ, Boller F, Soerensen PS, Griggs RC, Hachinski V, Hallett M, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Muscle Nerve. 2002 Feb; 25(2):133-4.

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Rosenberg RN, Aminoff M, Boller F, Soerensen PS, Griggs RC, Hallett M, Hachinski V, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Mov Disord. 2002 Jan; 17(1):3-4.

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Rosenberg RN, Aminoff M, Boller F, Soerensen PS, Griggs RC, Hachinski V, Hallett M, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all of the data. Arch Neurol. 2002 Jan; 59(1):27-8.

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Rosenberg RN, Aminoff M, Boller F, Soelberg P, Griggs RC, Hachinski V, Hallett M, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Stroke. 2001 Dec 1; 32(12):2734.

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Randomized pilot trial of betaINF1a (Avonex) in patients with inclusion body myositis. Neurology. 2001 Nov 13; 57(9):1566-70.

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Kissel JT, McDermott MP, Mendell JR, King WM, Pandya S, Griggs RC, Tawil R. Randomized, double-blind, placebo-controlled trial of albuterol in facioscapulohumeral dystrophy. Neurology. 2001 Oct 23; 57(8):1434-40.

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Udd B, Griggs R. Distal myopathies. Curr Opin Neurol. 2001 Oct; 14(5):561-6.

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Bendahhou S, Cummins TR, Griggs RC, Fu YH, Ptácek LJ. Sodium channel inactivation defects are associated with acetazolamide-exacerbated hypokalemic periodic paralysis. Ann Neurol. 2001 Sep; 50(3):417-20.

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Rose MR, McDermott MP, Thornton CA, Palenski C, Martens WB, Griggs RC. A prospective natural history study of inclusion body myositis: implications for clinical trials. Neurology. 2001 Aug 14; 57(3):548-50.

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Griggs RC. Chlamydia: conflict and controversy. Neurology. 2001 May 8; 56(9):1130.

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Fenichel GM, Griggs RC, Kissel J, Kramer TI, Mendell JR, Moxley RT, Pestronk A, Sheng K, Florence J, King WM, Pandya S, Robison VD, Wang H. A randomized efficacy and safety trial of oxandrolone in the treatment of Duchenne dystrophy. Neurology. 2001 Apr 24; 56(8):1075-9.

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Rosenberg RN, Aminoff M, Boller F, Soerensen PS, Griggs RC, Hallett M, Johnson RT, Kennard C, Lang AE, Lees AJ, Lisak R, Newsom-Davis J, Pedley TA, Selzer ME, Zochodne D. Reporting clinical trials: full access to all the data. Neurorehabil Neural Repair. 2001; 15(3):157-8.

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Griggs RC. Techniques for ventilatory support: clinical equipoise. Neurology. 2000 Sep 12; 55(5):615.

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Griggs RC, McGee K. Neurology: A journal for authors and readers. Neurology. 2000 Jul 12; 55(1):2.

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Bhatia KP, Griggs RC, Ptácek LJ. Episodic movement disorders as channelopathies. Mov Disord. 2000 May; 15(3):429-33.

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Forbes GB, Griggs RC, Moxley RT, Thornton CT, Tawil R. K-40 and dual-energy X-ray absorptiometry estimates of lean weight compared. Normals and patients with neuromuscular disease. Ann N Y Acad Sci. 2000 May; 904:111-4.

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Sansone V, Griggs RC, Moxley RT. Hypothyroidism unmasking proximal myotonic myopathy. Neuromuscul Disord. 2000 Mar; 10(3):165-72.

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Tawil R, McDermott MP, Brown R, Shapiro BC, Ptacek LJ, McManis PG, Dalakas MC, Spector SA, Mendell JR, Hahn AF, Griggs RC. Randomized trials of dichlorphenamide in the periodic paralyses. Working Group on Periodic Paralysis. Ann Neurol. 2000 Jan; 47(1):46-53.

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Griggs RC, Karpati G. Muscle pain, fatigue, and mitochondriopathies. N Engl J Med. 1999 Sep 30; 341(14):1077-8.

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Gifford DR, Holloway RG, Frankel MR, Albright CL, Meyerson R, Griggs RC, Vickrey BG. Improving adherence to dementia guidelines through education and opinion leaders. A randomized, controlled trial. Ann Intern Med. 1999 Aug 17; 131(4):237-46.

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Griggs RC, Ptácek LJ. Mutations of sodium channels in periodic paralysis: can they explain the disease and predict treatment? Neurology. 1999 Apr 22; 52(7):1309-10.

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Rose MR, Levin KH, Griggs RC. The dropped head plus syndrome: quantitation of response to corticosteroids. Muscle Nerve. 1999 Jan; 22(1):115-8.

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Orrell RW, Johnston HM, Gibson C, Cass RM, Griggs RC. Spontaneous abdominal hematoma in dermatomyositis. Muscle Nerve. 1998 Dec; 21(12):1800-3.

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Barohn RJ, Amato AA, Griggs RC. Overview of distal myopathies: from the clinical to the molecular. Neuromuscul Disord. 1998 Jun; 8(5):309-16.

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Milone M, Ohno K, Fukudome T, Shen XM, Brengman J, Griggs RC, Engel AG. Congenital myasthenic syndrome caused by novel loss-of-function mutations in the human AChR epsilon subunit gene. Ann N Y Acad Sci. 1998 May 13; 841:184-8.

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Kissel JT, McDermott MP, Natarajan R, Mendell JR, Pandya S, King WM, Griggs RC, Tawil R. Pilot trial of albuterol in facioscapulohumeral muscular dystrophy. FSH-DY Group. Neurology. 1998 May; 50(5):1402-6.

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Tawil R, Figlewicz DA, Griggs RC, Weiffenbach B. Facioscapulohumeral dystrophy: a distinct regional myopathy with a novel molecular pathogenesis. FSH Consortium. Ann Neurol. 1998 Mar; 43(3):279-82.

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Milone M, Wang HL, Ohno K, Prince R, Fukudome T, Shen XM, Brengman JM, Griggs RC, Sine SM, Engel AG. Mode switching kinetics produced by a naturally occurring mutation in the cytoplasmic loop of the human acetylcholine receptor epsilon subunit. Neuron. 1998 Mar; 20(3):575-88.

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Rose MR, Griggs RC. An unusual cause of quadriceps atrophy. Muscle Nerve. 1998 Feb; 21(2):233-5.

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Sansone V, Griggs RC, Meola G, Ptácek LJ, Barohn R, Iannaccone S, Bryan W, Baker N, Janas SJ, Scott W, Ririe D, Tawil R. Andersen's syndrome: a distinct periodic paralysis. Ann Neurol. 1997 Sep; 42(3):305-12.

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McComas AJ, Quartly C, Griggs RC. Early and late losses of motor units after poliomyelitis. Brain. 1997 Aug; 120 ( Pt 8):1415-21.

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Safety and efficacy of pramipexole in early Parkinson disease. A randomized dose-ranging study. Parkinson Study Group. JAMA. 1997 Jul 9; 278(2):125-30.

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Griggs RC. Changes in policy for publishing manuscripts in Neurology. Neurology. 1997 Jul; 49(1):1.

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Lou JS, Snyder R, Griggs RC. Refsum's disease: long term treatment preserves sensory nerve action potentials and motor function. J Neurol Neurosurg Psychiatry. 1997 Jun; 62(6):671-2.

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Griggs JJ, Commichau CS, Rapoport AP, Griggs RC. Chronic inflammatory demyelinating polyneuropathy in non-Hodgkin's lymphoma. Am J Hematol. 1997 Apr; 54(4):332-4.

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Tawil R, McDermott MP, Pandya S, King W, Kissel J, Mendell JR, Griggs RC. A pilot trial of prednisone in facioscapulohumeral muscular dystrophy. FSH-DY Group. Neurology. 1997 Jan; 48(1):46-9.

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A prospective, quantitative study of the natural history of facioscapulohumeral muscular dystrophy (FSHD): implications for therapeutic trials. The FSH-DY Group. Neurology. 1997 Jan; 48(1):38-46.

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Fouad G, Dalakas M, Servidei S, Mendell JR, Van den Bergh P, Angelini C, Alderson K, Griggs RC, Tawil R, Gregg R, Hogan K, Powers PA, Weinberg N, Malonee W, Ptácek LJ. Genotype-phenotype correlations of DHP receptor alpha 1-subunit gene mutations causing hypokalemic periodic paralysis. Neuromuscul Disord. 1997 Jan; 7(1):33-8.

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Engel AG, Ohno K, Bouzat C, Sine SM, Griggs RC. End-plate acetylcholine receptor deficiency due to nonsense mutations in the epsilon subunit. Ann Neurol. 1996 Nov; 40(5):810-7.

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Zhang J, George AL, Griggs RC, Fouad GT, Roberts J, Kwiecinski H, Connolly AM, Ptácek LJ. Mutations in the human skeletal muscle chloride channel gene (CLCN1) associated with dominant and recessive myotonia congenita. Neurology. 1996 Oct; 47(4):993-8.

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Thornton CA, Welle S, Griggs RC, Abraham GN. Human IgG production in vivo: determination of synthetic rate by nonradioactive tracer incorporation. J Immunol. 1996 Jul 15; 157(2):950-5.

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Rose MR, Kissel JT, Bickley LS, Griggs RC. Sustained myoglobinuria: the presenting manifestation of dermatomyositis. Neurology. 1996 Jul; 47(1):119-23.

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Tawil R, Forrester J, Griggs RC, Mendell J, Kissel J, McDermott M, King W, Weiffenbach B, Figlewicz D. Evidence for anticipation and association of deletion size with severity in facioscapulohumeral muscular dystrophy. The FSH-DY Group. Ann Neurol. 1996 Jun; 39(6):744-8.

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Santorelli FM, Sciacco M, Tanji K, Shanske S, Vu TH, Golzi V, Griggs RC, Mendell JR, Hays AP, Bertorini TE, Pestronk A, Bonilla E, DiMauro S. Multiple mitochondrial DNA deletions in sporadic inclusion body myositis: a study of 56 patients. Ann Neurol. 1996 Jun; 39(6):789-95.

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Griffin JW, Griggs RC, Barchi R, Schneck SA, Moses H. Opportunities and challenges in academic neurology: report of the Long Range Planning Committee of the American Neurological Association. Ann Neurol. 1996 Jun; 39(6):693-9.

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A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis. ALS CNTF Treatment Study Group. Neurology. 1996 May; 46(5):1244-9.

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Griggs RC, Bender AN, Tawil R. A puzzling case of periodic paralysis. Muscle Nerve. 1996 Mar; 19(3):362-4.

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Griggs RC, Askanas V, DiMauro S, Engel A, Karpati G, Mendell JR, Rowland LP. Inclusion body myositis and myopathies. Ann Neurol. 1995 Nov; 38(5):705-13.

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Tawil R, Myers GJ, Weiffenbach B, Griggs RC. Scapuloperoneal syndromes. Absence of linkage to the 4q35 FSHD locus. Arch Neurol. 1995 Nov; 52(11):1069-72.

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Browne DL, Brunt ER, Griggs RC, Nutt JG, Gancher ST, Smith EA, Litt M. Identification of two new KCNA1 mutations in episodic ataxia/myokymia families. Hum Mol Genet. 1995 Sep; 4(9):1671-2.

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Thornton C, Griggs RC, Moxley RT. PROMM syndrome (Ricker's disease) Ann Neurol. 1995 Aug; 38(2):273.

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Bejaoui K, Hirabayashi K, Hentati F, Haines JL, Ben Hamida C, Belal S, Miller RG, McKenna-Yasek D, Weissenbach J, Rowland LP, et al. Linkage of Miyoshi myopathy (distal autosomal recessive muscular dystrophy) locus to chromosome 2p12-14. Neurology. 1995 Apr; 45(4):768-72.

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Griggs RC, Nutt JG. Episodic ataxias as channelopathies. Ann Neurol. 1995 Mar; 37(3):285-7.

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Griggs RC, Tawil R, McDermott M, Forrester J, Figlewicz D, Weiffenbach B. Monozygotic twins with facioscapulohumeral dystrophy (FSHD): implications for genotype/phenotype correlation. FSH-DY Group. Muscle Nerve. 1995; 2:S50-5.

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Rifai Z, Welle S, Moxley RT, Lorenson M, Griggs RC. Effect of prednisone on protein metabolism in Duchenne dystrophy. Am J Physiol. 1995 Jan; 268(1 Pt 1):E67-74.

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Griggs RC, Tawil R, McDermott M, Forrester J, Figlewicz D, Weiffenbach B. Monozygotic twins with facioscapulohumeral dystrophy (FSHD): implications for genotype/phenotype correlation. Muscle Nerve Suppl. 1995; (2):S50-5.

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Griggs RC. Developing new treatments for muscle disease: prospects and promise. Curr Opin Neurol. 1994 Oct; 7(5):422-6.

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Calabresi PA, Silvestri G, DiMauro S, Griggs RC. Ekbom's syndrome: lipomas, ataxia, and neuropathy with MERRF. Muscle Nerve. 1994 Aug; 17(8):943-5.

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Ptácek LJ, Tawil R, Griggs RC, Meola G, McManis P, Barohn RJ, Mendell JR, Harris C, Spitzer R, Santiago F, et al. Sodium channel mutations in acetazolamide-responsive myotonia congenita, paramyotonia congenita, and hyperkalemic periodic paralysis. Neurology. 1994 Aug; 44(8):1500-3.

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Ptácek LJ, Tawil R, Griggs RC, Engel AG, Layzer RB, Kwiecinski H, McManis PG, Santiago L, Moore M, Fouad G, et al. Dihydropyridine receptor mutations cause hypokalemic periodic paralysis. Cell. 1994 Jun 17; 77(6):863-8.

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Griggs RC. Careers in academic neurology in the decade of the brain. Ann Neurol. 1994 Jun; 35(6):753-8.

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Thornton CA, Griggs RC, Moxley RT. Myotonic dystrophy with no trinucleotide repeat expansion. Ann Neurol. 1994 Mar; 35(3):269-72.

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Personius KE, Pandya S, King WM, Tawil R, McDermott MP. Facioscapulohumeral dystrophy natural history study: standardization of testing procedures and reliability of measurements. The FSH DY Group. Phys Ther. 1994 Mar; 74(3):253-63.

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Thornton CA, Griggs RC. Plasma exchange and intravenous immunoglobulin treatment of neuromuscular disease. Ann Neurol. 1994 Mar; 35(3):260-8.

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Tawil R, McDermott MP, Mendell JR, Kissel J, Griggs RC. Facioscapulohumeral muscular dystrophy (FSHD): design of natural history study and results of baseline testing. FSH-DY Group. Neurology. 1994 Mar; 44(3 Pt 1):442-6.

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Tawil R, Ptacek LJ, Pavlakis SG, DeVivo DC, Penn AS, Ozdemir C, Griggs RC. Andersen's syndrome: potassium-sensitive periodic paralysis, ventricular ectopy, and dysmorphic features. Ann Neurol. 1994 Mar; 35(3):326-30.

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Muscat GE, Mynett-Johnson L, Dowhan D, Downes M, Griggs R. Activation of myoD gene transcription by 3,5,3'-triiodo-L-thyronine: a direct role for the thyroid hormone and retinoid X receptors. Nucleic Acids Res. 1994 Feb 25; 22(4):583-91.

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Rifai Z, Klitzke M, Tawil R, Kazee AM, Shanske S, DiMauro S, Griggs RC. Dementia of adult polyglucosan body disease. Evidence of cortical and subcortical dysfunction. Arch Neurol. 1994 Jan; 51(1):90-4.

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Griggs RC, Tawil R, Storvick D, Mendell JR, Altherr MR. Genetics of facioscapulohumeral muscular dystrophy: new mutations in sporadic cases. Neurology. 1993 Nov; 43(11):2369-72.

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Downes M, Griggs R, Atkins A, Olson EN, Muscat GE. Identification of a thyroid hormone response element in the mouse myogenin gene: characterization of the thyroid hormone and retinoid X receptor heterodimeric binding site. Cell Growth Differ. 1993 Nov; 4(11):901-9.

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Rifai Z, Kazee AM, Kamp C, Griggs RC. Intranuclear rods in severe congenital nemaline myopathy. Neurology. 1993 Nov; 43(11):2372-7.

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Engel AG, Hutchinson DO, Nakano S, Murphy L, Griggs RC, Gu Y, Hall ZW, Lindstrom J. Myasthenic syndromes attributed to mutations affecting the epsilon subunit of the acetylcholine receptor. Ann N Y Acad Sci. 1993 Jun 21; 681:496-508.

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Weiffenbach B, Dubois J, Storvick D, Tawil R, Jacobsen SJ, Gilbert J, Wijmenga C, Mendell JR, Winokur S, Altherr MR, et al. Mapping the facioscapulohumeral muscular dystrophy gene is complicated by chromsome 4q35 recombination events. Nat Genet. 1993 Jun; 4(2):165-9.

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Tawil R, Moxley RT, Griggs RC. Acetazolamide-induced nephrolithiasis: implications for treatment of neuromuscular disorders. Neurology. 1993 Jun; 43(6):1105-6.

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Muscat GE, Griggs R, Downes M, Emery J. Characterization of the thyroid hormone response element in the skeletal alpha-actin gene: negative regulation of T3 receptor binding by the retinoid X receptor. Cell Growth Differ. 1993 Apr; 4(4):269-79.

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A controlled trial of lazabemide (RO19-6327) in untreated Parkinson's disease. Parkinson Study Group. Ann Neurol. 1993 Apr; 33(4):350-6.

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Griggs RC, Moxley RT, Mendell JR, Fenichel GM, Brooke MH, Pestronk A, Miller JP, Cwik VA, Pandya S, Robison J, et al. Duchenne dystrophy: randomized, controlled trial of prednisone (18 months) and azathioprine (12 months) Neurology. 1993 Mar; 43(3 Pt 1):520-7.

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Kissel JT, Lynn DJ, Rammohan KW, Klein JP, Griggs RC, Moxley RT, Cwik VA, Brooke MH, Mendell JR. Mononuclear cell analysis of muscle biopsies in prednisone- and azathioprine-treated Duchenne muscular dystrophy. Neurology. 1993 Mar; 43(3 Pt 1):532-6.

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Ptacek LJ, Johnson KJ, Griggs RC. Genetics and physiology of the myotonic muscle disorders. N Engl J Med. 1993 Feb 18; 328(7):482-9.

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Tawil R, Storvick D, Feasby TE, Weiffenbach B, Griggs RC. Extreme variability of expression in monozygotic twins with FSH muscular dystrophy. Neurology. 1993 Feb; 43(2):345-8.

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Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. The Parkinson Study Group. N Engl J Med. 1993 Jan 21; 328(3):176-83.

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Tawil R, Storvick D, Weiffenbach B, Altherr MR, Feasby TE, Griggs RC. Chromosome 4q DNA rearrangement in monozygotic twins discordant for facioscapulohumeral muscular dystrophy. Hum Mutat. 1993; 2(6):492-4.

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Griggs RC, Ptácek LJ. The periodic paralyses. Hosp Pract (Off Ed). 1992 Nov 15; 27(11):123-6, 129-30, 136-7.

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Warner CL, Griffin JE, Wilson JD, Jacobs LD, Murray KR, Fischbeck KH, Dickoff D, Griggs RC. X-linked spinomuscular atrophy: a kindred with associated abnormal androgen receptor binding. Neurology. 1992 Nov; 42(11):2181-4.

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Weiffenbach B, Bagley R, Falls K, Hyser C, Storvick D, Jacobsen SJ, Schultz P, Mendell J, Willems van Dijk K, Milner EC, et al. Linkage analyses of five chromosome 4 markers localizes the facioscapulohumeral muscular dystrophy (FSHD) gene to distal 4q35. Am J Hum Genet. 1992 Aug; 51(2):416-23.

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Ptácek LJ, George AL, Barchi RL, Griggs RC, Riggs JE, Robertson M, Leppert MF. Mutations in an S4 segment of the adult skeletal muscle sodium channel cause paramyotonia congenita. Neuron. 1992 May; 8(5):891-7.

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Griggs RC, Dickinson JC. Who teaches neurology to the non-neurologist? Neurology. 1992 Apr; 42(4):719-21.

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Ptacek LJ, Tawil R, Griggs RC, Storvick D, Leppert M. Linkage of atypical myotonia congenita to a sodium channel locus. Neurology. 1992 Feb; 42(2):431-3.

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Welle S, Jozefowicz R, Forbes G, Griggs RC. Effect of testosterone on metabolic rate and body composition in normal men and men with muscular dystrophy. J Clin Endocrinol Metab. 1992 Feb; 74(2):332-5.

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Forbes GB, Porta CR, Herr BE, Griggs RC. Sequence of changes in body composition induced by testosterone and reversal of changes after drug is stopped. JAMA. 1992 Jan 15; 267(3):397-9.

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Shoulson I. An interim report of the effect of selegiline (L-deprenyl) on the progression of disability in early Parkinson's disease. The Parkinson Study Group. Eur Neurol. 1992; 32 Suppl 1:46-53.

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Weiffenbach B, Bagley RG, Falls K, Dubois J, Hyser C, Storvick D, Schultz P, Mendell JR, Milner EC, Jacobsen SJ, et al. Framework multipoint map of the long arm of human chromosome 4 and telomeric localization of the gene for FSHD. Mamm Genome. 1992; 3(3):143-50.

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Fenichel GM, Florence JM, Pestronk A, Mendell JR, Moxley RT, Griggs RC, Brooke MH, Miller JP, Robison J, King W, et al. Long-term benefit from prednisone therapy in Duchenne muscular dystrophy. Neurology. 1991 Dec; 41(12):1874-7.

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Ptácek LJ, George AL, Griggs RC, Tawil R, Kallen RG, Barchi RL, Robertson M, Leppert MF. Identification of a mutation in the gene causing hyperkalemic periodic paralysis. Cell. 1991 Nov 29; 67(5):1021-7.

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Barohn RJ, Miller RG, Griggs RC. Autosomal recessive distal dystrophy. Neurology. 1991 Sep; 41(9):1365-70.

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DATATOP and clinical neuromythology IX. Neurology. 1991 Jun; 41(6):771-7.

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Fenichel GM, Mendell JR, Moxley RT, Griggs RC, Brooke MH, Miller JP, Pestronk A, Robison J, King W, Signore L, et al. A comparison of daily and alternate-day prednisone therapy in the treatment of Duchenne muscular dystrophy. Arch Neurol. 1991 Jun; 48(6):575-9.

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Burrow KL, Coovert DD, Klein CJ, Bulman DE, Kissel JT, Rammohan KW, Burghes AH, Mendell JR. Dystrophin expression and somatic reversion in prednisone-treated and untreated Duchenne dystrophy. CIDD Study Group. Neurology. 1991 May; 41(5):661-6.

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Kissel JT, Burrow KL, Rammohan KW, Mendell JR. Mononuclear cell analysis of muscle biopsies in prednisone-treated and untreated Duchenne muscular dystrophy. CIDD Study Group. Neurology. 1991 May; 41(5):667-72.

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Griggs RC, Moxley RT, Mendell JR, Fenichel GM, Brooke MH, Pestronk A, Miller JP. Prednisone in Duchenne dystrophy. A randomized, controlled trial defining the time course and dose response. Clinical Investigation of Duchenne Dystrophy Group. Arch Neurol. 1991 Apr; 48(4):383-8.

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Griggs RC, Karpati G. The pathogenesis of dermatomyositis. Arch Neurol. 1991 Jan; 48(1):21-2.

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Griggs RC, Moxley RT, Mendell JR, Fenichel GM, Brooke MH, Miller PJ, Mandel S, Florence J, Schierbecker J, Kaiser KK, et al. Randomized, double-blind trial of mazindol in Duchenne dystrophy. Muscle Nerve. 1990 Dec; 13(12):1169-73.

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Griggs RC, Jozefowicz R, Kingston W, Nair KS, Herr BE, Halliday D. Mechanism of muscle wasting in myotonic dystrophy. Ann Neurol. 1990 May; 27(5):505-12.

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Griggs RC. Quantitation of muscle mass and muscle protein synthesis rate: documenting a response to myoblast transfer. Adv Exp Med Biol. 1990; 280:235-40.

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Griggs RC. The use of pulmonary function testing as a quantitative measurement for therapeutic trials. Muscle Nerve. 1990; 13 Suppl:S30-4.

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Effect of deprenyl on the progression of disability in early Parkinson's disease. The Parkinson Study Group. N Engl J Med. 1989 Nov 16; 321(20):1364-71.

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Mendell JR, Moxley RT, Griggs RC, Brooke MH, Fenichel GM, Miller JP, King W, Signore L, Pandya S, Florence J, et al. Randomized, double-blind six-month trial of prednisone in Duchenne's muscular dystrophy. N Engl J Med. 1989 Jun 15; 320(24):1592-7.

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Brooke MH, Fenichel GM, Griggs RC, Mendell JR, Moxley R, Florence J, King WM, Pandya S, Robison J, Schierbecker J, et al. Duchenne muscular dystrophy: patterns of clinical progression and effects of supportive therapy. Neurology. 1989 Apr; 39(4):475-81.

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Griggs RC, Wood DS. Criteria for establishing the validity of genetic recombination in myotonic dystrophy. Neurology. 1989 Mar; 39(3):420-1.

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Griggs RC, Pandya S, Florence JM, Brooke MH, Kingston W, Miller JP, Chutkow J, Herr BE, Moxley RT. Randomized controlled trial of testosterone in myotonic dystrophy. Neurology. 1989 Feb; 39(2 Pt 1):219-22.

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Griggs RC, Kingston W, Jozefowicz RF, Herr BE, Forbes G, Halliday D. Effect of testosterone on muscle mass and muscle protein synthesis. J Appl Physiol. 1989 Jan; 66(1):498-503.

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Fenichel GM, Brooke MH, Griggs RC, Mendell JR, Miller JP, Moxley RT, Park JH, Provine MA, Florence J, Kaiser KK, et al. Clinical investigation in Duchenne muscular dystrophy: penicillamine and vitamin E. Muscle Nerve. 1988 Nov; 11(11):1164-8.

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Jozefowicz RF, Griggs RC. Myotonic dystrophy. Neurol Clin. 1988 Aug; 6(3):455-72.

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Nair KS, Halliday D, Griggs RC. Leucine incorporation into mixed skeletal muscle protein in humans. Am J Physiol. 1988 Feb; 254(2 Pt 1):E208-13.

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Hyser CL, Province M, Griggs RC, Mendell JR, Fenichel GM, Brooke MH, Miller JP, Polakowska R, Doherty RA, Quirk S, et al. Genetic heterogeneity in Duchenne dystrophy. Ann Neurol. 1987 Oct; 22(4):553-5.

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Kurlan R, Jankovic J, Rubin A, Patten B, Griggs R, Shoulson I. Coexistent Meige's syndrome and myasthenia gravis. A relationship between blinking and extraocular muscle fatigue? Arch Neurol. 1987 Oct; 44(10):1057-60.

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Hyser CL, Doherty RA, Griggs RC, Mendell JR, Polakowska R, Quirk S, Brooke MH, Fenichel GM. Carrier assessment for mothers and sisters of isolated Duchenne dystrophy cases: the importance of serum enzyme determinations. Neurology. 1987 Sep; 37(9):1476-80.

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Mendell JR, Province MA, Moxley RT, Griggs RC, Brooke MH, Fenichel GM, Miller JP, Kaiser KK, King W, Robison J, et al. Clinical investigation of Duchenne muscular dystrophy. A methodology for therapeutic trials based on natural history controls. Arch Neurol. 1987 Aug; 44(8):808-11.

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Brooke MH, Fenichel GM, Griggs RC, Mendell JR, Moxley RT, Miller JP, Kaiser KK, Florence JM, Pandya S, Signore L, et al. Clinical investigation of Duchenne muscular dystrophy. Interesting results in a trial of prednisone. Arch Neurol. 1987 Aug; 44(8):812-7.

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Jozefowicz RF, Welle SL, Nair KS, Kingston WJ, Griggs RC. Basal metabolic rate in myotonic dystrophy: evidence against hypometabolism. Neurology. 1987 Jun; 37(6):1021-5.

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Moxley RT, Kingston WJ, Griggs RC, Livingston JN. Lack of rapid enhancement of insulin action after oral glucose challenge in myotonic dystrophy. Diabetes. 1987 Jun; 36(6):693-701.

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Trudell RG, Kaiser KK, Griggs RC. Acetazolamide-responsive myotonia congenita. Neurology. 1987 Mar; 37(3):488-91.

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Griggs RC, Martin JB, Penn AS, Roses AD, Toole JF. Training clinical neuroscientists. Ann Neurol. 1987 Feb; 21(2):197-201.

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Moxley RT, Brooke MH, Fenichel GM, Mendell JR, Griggs RC, Miller JP, Province MA, Patterson V. Clinical investigation in Duchenne dystrophy. VI. Double-blind controlled trial of nifedipine. Muscle Nerve. 1987 Jan; 10(1):22-33.

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Hyser CL, Griggs RC, Mendell JR, Polakowska R, Quirk S, Brooke MH, Fenichel GM, Doherty RA. Use of serum creatine kinase, pyruvate kinase, and genetic linkage for carrier detection in Duchenne and Becker dystrophy. Neurology. 1987 Jan; 37(1):4-10.

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Griggs RC, Halliday D, Kingston W, Moxley RT. Effect of testosterone on muscle protein synthesis in myotonic dystrophy. Ann Neurol. 1986 Nov; 20(5):590-6.

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Kingston WJ, Moxley RT, Griggs RC. Effect of testosterone on whole body amino acid utilization in myotonic dystrophy. Metabolism. 1986 Oct; 35(10):928-32.

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McCool FD, Mayewski RF, Shayne DS, Gibson CJ, Griggs RC, Hyde RW. Intermittent positive pressure breathing in patients with respiratory muscle weakness. Alterations in total respiratory system compliance. Chest. 1986 Oct; 90(4):546-52.

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Ramirez JA, Mendell JR, Warmolts JR, Griggs RC. Phenytoin neuropathy: structural changes in the sural nerve. Ann Neurol. 1986 Feb; 19(2):162-7.

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Kissel JT, Levy RJ, Mendell JR, Griggs RC. Azathioprine toxicity in neuromuscular disease. Neurology. 1986 Jan; 36(1):35-9.

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Torres CF, Griggs RC, Goetz JP. Severe neonatal centronuclear myopathy with autosomal dominant inheritance. Arch Neurol. 1985 Oct; 42(10):1011-4.

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Griggs RC, Kingston W, Herr BE, Forbes G, Moxley RT. Lack of relationship of hypogonadism to muscle wasting in myotonic dystrophy. Arch Neurol. 1985 Sep; 42(9):881-5.

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Pandya S, Florence JM, King WM, Robison JD, Oxman M, Province MA. Reliability of goniometric measurements in patients with Duchenne muscular dystrophy. Phys Ther. 1985 Sep; 65(9):1339-42.

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Griggs RC, Kingston W, Herr BE, Forbes G, Moxley RT. Myotonic dystrophy: effect of testosterone on total body potassium and on creatinine excretion. Neurology. 1985 Jul; 35(7):1035-40.

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Moxley RT. Absence of major side effects of nifedipine following treatment of Duchenne dystrophy. Pediatrics. 1985 Jun; 75(6):1168-9.

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Mendell JR, Sahenk Z, Whitaker JN, Trapp BD, Yates AJ, Griggs RC, Quarles RH. Polyneuropathy and IgM monoclonal gammopathy: studies on the pathogenetic role of anti-myelin-associated glycoprotein antibody. Ann Neurol. 1985 Mar; 17(3):243-54.

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Moxley RT, Kingston W, Griggs RC. Abnormal regulation of venous alanine after glucose ingestion in myotonic dystrophy. Clin Sci (Lond). 1985 Feb; 68(2):151-7.

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Halliday D, Ford GC, Edwards RH, Rennie MJ, Griggs RC. In vivo estimation of muscle protein synthesis in myotonic dystrophy. Ann Neurol. 1985 Jan; 17(1):65-9.

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Griggs RC, Mendell JR, Brooke MH, Fenichel GM, Miller JP, Province M, Moxley RT, Huntzinger D, Vaughn A, Cohen M, et al. Clinical investigation in Duchenne dystrophy: V. Use of creatine kinase and pyruvate kinase in carrier detection. Muscle Nerve. 1985 Jan; 8(1):60-7.

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Mendell JR, Griggs RC, Moxley RT, Fenichel GM, Brooke MH, Miller JP, Province MA, Dodson WE. Clinical investigation in Duchenne muscular dystrophy: IV. Double-blind controlled trial of leucine. Muscle Nerve. 1984 Sep; 7(7):535-41.

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Corbett A, Kingston W, Griggs RC, Moxley RT. Effect of acetazolamide on insulin sensitivity in myotonic disorders. Arch Neurol. 1984 Jul; 41(7):740-3.

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Read WW, Read MA, Rennie MJ, Griggs RC, Halliday D. Preparation of CO2 from blood and protein-bound amino acid carboxyl groups for quantification and 13C-isotope measurements. Biomed Mass Spectrom. 1984 Jul; 11(7):348-52.

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Riggs JE, Griggs RC, Moxley RT. Dissociation of glucose and potassium arterial-venous differences across the forearm by acetazolamide. A possible relationship to acetazolamide's beneficial effect in hypokalemic periodic paralysis. Arch Neurol. 1984 Jan; 41(1):35-8.

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Griggs RC, Resnick J, Engel WK. Intravenous treatment of hypokalemic periodic paralysis. Arch Neurol. 1983 Sep; 40(9):539-40.

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Torres C, Moxley RT, Griggs RC. Quantitative testing of handgrip strength, myotonia, and fatigue in myotonic dystrophy. J Neurol Sci. 1983 Jul; 60(1):157-68.

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Bach PR. Determination of nifedipine in serum or plasma by reversed-phase liquid chromatography. Clin Chem. 1983 Jul; 29(7):1344-8.

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Moxley RT, Griggs RC, Forbes GB, Goldblatt D, Donohoe K. Influence of muscle wasting on oral glucose tolerance testing. Clin Sci (Lond). 1983 Jun; 64(6):601-9.

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Riggs JE, Griggs RC, Gutmann L. Hypokalemic myopathy in hyperemesis gravidarum: its historical significance. W V Med J. 1983 May; 79(5):95-7.

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Kurlan R, Griggs RC. Cyanotic congenital heart disease with suspected stroke. Should all patients receive antibiotics? Arch Neurol. 1983 Apr; 40(4):209-12.

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Brooke MH, Fenichel GM, Griggs RC, Mendell JR, Moxley R, Miller JP, Province MA. Clinical investigation in Duchenne dystrophy: 2. Determination of the "power" of therapeutic trials based on the natural history. Muscle Nerve. 1983 Feb; 6(2):91-103.

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Griggs RC, Rennie MJ. Muscle wasting in muscular dystrophy: decreased protein synthesis or increased degradation? Ann Neurol. 1983 Feb; 13(2):125-32.

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Griggs RC, Forbes G, Moxley RT, Herr BE. The assessment of muscle mass in progressive neuromuscular disease. Neurology. 1983 Feb; 33(2):158-65.

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Kudo M, Griggs RC. Diagnostic usefulness of intramuscular nerve bundles. Arch Pathol Lab Med. 1982 Jul; 106(7):355-9.

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Faillace RT, Kingston WJ, Nanda NC, Griggs RC. Cardiomyopathy associated with the syndrome of amyotrophic chorea and acanthocytosis. Ann Intern Med. 1982 May; 96(5):616-7.

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Corbett AJ, Griggs RC, Moxley RT. Skeletal muscle catabolism in amyotrophic lateral sclerosis and chronic spinal muscular atrophy. Neurology. 1982 May; 32(5):550-2.

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Ringel SP, Forstot JZ, Tan EM, Wehling C, Griggs RC, Butcher D. Sjögren's syndrome and polymyositis or dermatomyositis. Arch Neurol. 1982 Mar; 39(3):157-63.

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McCusker EA, Rudick RA, Honch GW, Griggs RC. Recovery from the 'locked-in' syndrome. Arch Neurol. 1982 Mar; 39(3):145-7.

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Griggs RC, Donohoe KM. The recognition and management of respiratory insufficiency in neuromuscular disease. J Chronic Dis. 1982; 35(7):497-500.

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Torres CF, Griggs RC, Moxley RT, Bender AN. Hypokalemic periodic paralysis exacerbated by acetazolamide. Neurology. 1981 Nov; 31(11):1423-8.

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Riggs JE, Moxley RT, Griggs RC, Horner FA. Hyperkalemic periodic paralysis: an apparent sporadic case. Neurology. 1981 Sep; 31(9):1157-9.

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Riggs JE, Griggs RC, Moxley RT, Lewis ED. Acute effects of acetazolamide in hyperkalemic periodic paralysis. Neurology. 1981 Jun; 31(6):725-9.

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Brooke MH, Griggs RC, Mendell JR, Fenichel GM, Shumate JB, Pellegrino RJ. Clinical trial in Duchenne dystrophy. I. The design of the protocol. Muscle Nerve. 1981 May-Jun; 4(3):186-97.

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Pabico RC, Gruebel BJ, McKenna BA, Griggs RC, Hollander J, Nusbacher J, Panner BJ. Renal involvement in Refsum's disease. Am J Med. 1981 May; 70(5):1136-43.

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Moxley RT, Livingston JN, Lockwood DH, Griggs RC, Hill RL. Abnormal regulation of monocyte insulin-binding affinity after glucose ingestion in patients with myotonic dystrophy. Proc Natl Acad Sci U S A. 1981 Apr; 78(4):2567-71.

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Iannaccone ST, Griggs RC. Animal model for EACA-induced myopathy. Muscle Nerve. 1981 Mar-Apr; 4(2):176.

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Brooke MH, Griggs RC, Mendell JR, Fenichel GM, Shumate JB. The natural history of Duchenne muscular dystrophy: a caveat for therapeutic trials. Trans Am Neurol Assoc. 1981; 106:195-9.

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Griggs RC, Pandya S, Moxley RT, Forbes G, VanDyke DH, Pearce FJ. Treatment of myopathic carnitine deficiency: quantitation of response to prednisone and carnitine. Trans Am Neurol Assoc. 1981; 106:199-202.

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Griggs RC, Donohoe KM, Utell MJ, Goldblatt D, Moxley RT. Evaluation of pulmonary function in neuromuscular disease. Arch Neurol. 1981 Jan; 38(1):9-12.

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Griggs RC, Moxley RT, Forbes GB. 3-methylhistidine excretion in myotonic dystrophy. Neurology. 1980 Dec; 30(12):1262-7.

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Moxley RT, Griggs RC, Goldblatt D. Muscle insulin resistance in myotonic dystrophy: effect of supraphysiologic insulinization. Neurology. 1980 Oct; 30(10):1077-83.

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Greenland P, Griggs RC. Arrhythmic complications in the Guillain-Barré syndrome. Arch Intern Med. 1980 Aug; 140(8):1053-5.

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Riggs JE, Griggs RC, Rosenfeld SI, May AG, Penn AS. Heterozygous C2-deficiency and myasthenia gravis. Neurology. 1980 Aug; 30(8):871-3.

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Reeves WC, Griggs R, Nanda NC, Thomson K, Gramiak R. Echocardiographic evaluation of cardiac abnormalities in Duchenne's dystrophy and myotonic muscular dystrophy. Arch Neurol. 1980 May; 37(5):273-7.

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Torres CF, Griggs RC, Baum J, Penn AS. Penicillamine-induced myasthenia gravis in progressive systemic sclerosis. Arthritis Rheum. 1980 Apr; 23(4):505-8.

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McCusker EA, Rudick RA, Honch GW, Griggs RC. Recovery from the locked-in syndrome. Trans Am Neurol Assoc. 1980; 105:17-21.

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Lewis ED, Griggs RC, Moxley RT. Regulation of plasma potassium in hyperkalemic periodic paralysis. Neurology. 1979 Aug; 29(8):1131-7.

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Osher RH, Griggs RC. Orbicularis fatigue: the 'peek' sign of myasthenia gravis. Arch Ophthalmol. 1979 Apr; 97(4):677-9.

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Griggs RC, Moxley RT, Lafrance RA, McQuillen J. Hereditary paroxysmal ataxia: response to acetazolamide. Neurology. 1978 Dec; 28(12):1259-64.

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Moxley RT, Griggs RC, Markesbery WR, Vangelder V. Metabolic implications of distal atrophy. Carbohydrate metabolism in centronuclear myopathy. J Neurol Sci. 1978 Dec; 39(2-3):247-59.

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Moxley RT, Griggs RC, Goldblatt D, VanGelder V, Herr BE, Thiel R. Decreased insulin sensitivity of forearm muscle in myotonic dystrophy. J Clin Invest. 1978 Oct; 62(4):857-67.

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Griggs RC, Moxley RT, Riggs JE, Engel WK. Effects of acetazolamide on myotonia. Ann Neurol. 1978 Jun; 3(6):531-7.

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Penovich PE, Hollander J, Nusbacher JA, Griggs RC, MacPherson J. Note on plasma exchange therapy in Refsum's disease. Adv Neurol. 1978; 21:151-3.

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Markesbery WR, Griggs RC, Herr B. Distal myopathy: electron microscopic and histochemical studies. Neurology. 1977 Aug; 27(8):727-35.

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Riggs JE, Griggs RC, Moxley RT. Acetazolamide-induced weakness in paramyotonia congenita. Ann Intern Med. 1977 Feb; 86(2):169-73.

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Griggs RC. The myotonic disorders and the periodic paralyses. Adv Neurol. 1977; 17:143-59.

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Griggs RC. Perspectives on the treatment of neuromuscular disease. Adv Neurol. 1977; 17:1-12.

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Griggs RC, Moxley RT, Riggs JE, Engel WK. Effect of acetazolamide on myotonia. Trans Am Neurol Assoc. 1977; 102:133-5.

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Griggs RC, Nash R. Diphasic response to corticosteroids in idiopathic relapsing polyneuropathy. Arch Neurol. 1976 Nov; 33(11):794-5.

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Herr BE, Coleman PD, Griggs RC. A Bodian method for mounted frozen sections. Stain Technol. 1976 Sep; 51(5):261-5.

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Winters SJ, Schreiner B, Griggs RC, Rowley P, Nanda NC. Familial mitral valve prolapse and myotonic dystrophy. Ann Intern Med. 1976 Jul; 85(1):19-22.

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Bosmann HB, Gersten DM, Griggs RC, Howland JL, Hudecki MS, Katyare S, McLaughlin J. Erythrocyte surface membrane alterations. Arch Neurol. 1976 Feb; 33(2):135-8.

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Griggs RC, Davis RJ, Anderson DC, Dove JT. Cardiac conduction in myotonic dystrophy. Am J Med. 1975 Jul; 59(1):37-42.

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Griggs RC, Markesbery WR, Bauman AW, Callerame ML. Perivascular hemosiderin deposition in muscle in Waldenström's macroglobulinemia. J Neurol Sci. 1975 Jun; 25(2):153-63.

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VanDyke DH, Griggs RC, Murphy MJ, Goldstein MN. Hereditary myokymia and periodic ataxia. J Neurol Sci. 1975 May; 25(1):109-18.

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VanDyke DH, Griggs RC, Markesbery W, Dimauro S. Hereditary carnitine deficiency of muscle. Neurology. 1975 Feb; 25(2):154-9.

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Leddy JP, Griggs RC, Klemperer MR, Frank MM. Hereditary complement (C2) deficiency with dermatomyositis. Am J Med. 1975 Jan; 58(1):83-91.

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Iannaccone ST, Griggs RC, Markesbery WR, Joynt RJ. Familial progressive external ophthalmoplegia and ragged-red fibers. Neurology. 1974 Nov; 24(11):1033-8.

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Griggs RC. Hypertrophy and cardiomyopathy in the neuromuscular diseases. Circ Res. 1974 Aug; 35(2):suppl II:145-51.

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Markesbery WR, Griggs RC, Leach RP, Lapham LW. Late onset hereditary distal myopathy. Neurology. 1974 Feb; 24(2):127-34.

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Griggs RC, Markesbery WR, Condemi JJ. Cerebral mass due to sarcoidosis. Regression during corticosteroid therapy. Neurology. 1973 Sep; 23(9):981-9.

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Griggs RC, Condemi JJ, Vaughan JH. Effect of therapeutic dosages of prednisone on human immunoglobulin G metabolism. J Allergy Clin Immunol. 1972 May; 49(5):267-73.

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Hardin JA, Griggs RC. Diazepam treatment in a case of strychnine poisoning. Lancet. 1971 Aug 14; 2(7720):372-3.

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Griggs RC, Engel WK, Resnick JS. Acetazolamide treatment of hypokalemic periodic paralysis. Prevention of attacks and improvement of persistent weakness. Ann Intern Med. 1970 Jul; 73(1):39-48.

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Griggs RC, Strober W, McFarlin DE. Recurrent encephalopathy associated with low molecular weight gamma-globulin 19S in the serum and cerebrospinal fluid. Arch Neurol. 1969 Sep; 21(3):303-14.

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Goden P, Griggs RC, Nissley SP, Roth J, Engel WK. Studies of plasma insulin in myotonic dystrophy. J Clin Endocrinol Metab. 1969 May; 29(5):684-90.

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Hines JD, Halsted CH, Griggs RC, Harris JW. Megaloblastic anemia secondary to folate deficiency associated with hypothyroidism. Ann Intern Med. 1968 Apr; 68(4):792-805.

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Resnick JS, Engel WK, Griggs RC, Stam AC. Acetazolamide prophylaxis in hypokalemic periodic paralysis. N Engl J Med. 1968 Mar 14; 278(11):582-6.

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McFarlin DE, Griggs RC. Treatment of inflammatory myopathies with azathioprine. Trans Am Neurol Assoc. 1968; 93:244-6.

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Griggs RC, McFarlin DE, Engel WK. Severe occult juvenile myasthenia gravis responsive to long-term corticosteroid therapy. Trans Am Neurol Assoc. 1968; 93:216-8.

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HALL PW, DAMMIN GJ, GRIGGS RC, FAJGELJ A, ZIMONJIC B, GAON J. INVESTIGATION OF CHRONIC ENDEMIC NEPHROPATHY IN YUGOSLAVIA. II. RENAL PATHOLOGY. Am J Med. 1965 Aug; 39:210-7.

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GRIGGS RC, SUNSHINE I, NEWILL VA, NEWTON BW, BUCHANAN S, RASCH CA. ENVIRONMENTAL FACTORS IN CHILDHOOD LEAD POISONING. JAMA. 1964 Mar 7; 187:703-7.

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GRIGGS RC, WEISMAN R, HARRIS JW. Alterations in osmotic and mechanical fragility related to in vivo erythrocyte aging and splenic sequestration in hereditary spherocytosis. J Clin Invest. 1960 Jan; 39:89-101.

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