URMC Research Network

Find People
Keyword
Last Name
 
More Search Options

Paul Rubery

TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentOrthopaedics
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 665
Rochester NY 14642
Other Positions
TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentPediatrics

 
 Awards And Honors
1984     Omicron Delta Kappa Leadership Honor Society, The Johns Hopkins University
1987     Alpha Omega Alpha, Cornell University Medical College
1988     T.Campbell Thompson Prize in Orthopaedics, Cornell University Medical College
1993     POCNY research prize for best resident paper at Pediatric Orthopaedic Club of New York annual research night
2009     Best Doctors in America for Spinal Surgery
 
 Overview
The use of gene transfer to improve cartilage repair, ligament healing, and restoration of various additional tissues, including tendon and meniscus shows great promise. Other applications include intervertebral disc degeneration, aseptic loosening, osteoporosis, genetic diseases, and orthopaedic tumors. Dr. Rubery's research focuses on finding gene delivery systems that can mediate site-specific transduction restricted to within the margins of the defect during routine arthroscopy. He serves as a consulting scientist for LAGeT Musculoskeletal, LLC in the development of a technology process, termed LAGT (Light Activated Gene Therapy) for articular and meniscal cartilage repair, ligament and tendon healing and enhanced spinal fusion.

 
 Selected Publications
List All   |   Timeline
  1. Offley SC, Coyne E, Horodyski M, Rubery PT, Zeidman SM, Rechtine GR. Randomized trial demonstrates that extended-release epidural morphine may provide safe pain control for lumbar surgery patients. Surg Neurol Int. 2013; 4(Suppl 2):S51-7.
    View in: PubMed
  2. Rubery PT, Brown R, Prasarn M, Small J, Conrad B, Horodyski M, Rechtine G. Stabilization of 2-column thoracolumbar fractures with orthoses: a cadaver model. Spine (Phila Pa 1976). 2013 Mar 1; 38(5):E270-5.
    View in: PubMed
  3. Wang M, Tang D, Shu B, Wang B, Jin H, Hao S, Dresser KA, Shen J, Im HJ, Sampson ER, Rubery PT, Zuscik MJ, Schwarz EM, O'Keefe RJ, Wang Y, Chen D. Conditional activation of ß-catenin signaling in mice leads to severe defects in intervertebral disc tissue. Arthritis Rheum. 2012 Aug; 64(8):2611-23.
    View in: PubMed
  4. Prasarn ML, Horodyski M, Conrad B, Rubery PT, Dubose D, Small J, Rechtine GR. Comparison of external fixation versus the trauma pelvic orthotic device on unstable pelvic injuries: a cadaveric study of stability. J Trauma Acute Care Surg. 2012 Jun; 72(6):1671-5.
    View in: PubMed
  5. Prasarn ML, Conrad B, Rubery PT, Wendling A, Aydog T, Horodyski M, Rechtine GR. Comparison of 4 airway devices on cervical spine alignment in a cadaver model with global ligamentous instability at C5-C6. Spine (Phila Pa 1976). 2012 Mar 15; 37(6):476-81.
    View in: PubMed
  6. Papuga MO, Kwok E, You Z, Rubery PT, Dougherty PE, Pryhuber G, Beck CA, Hilton MJ, Awad HA, Schwarz EM. TNF is required for the induction but not the maintenance of compression-induced BME signals in murine tail vertebrae: limitations of anti-TNF therapy for degenerative disc disease. J Orthop Res. 2011 Sep; 29(9):1367-74.
    View in: PubMed
  7. Papuga MO, Proulx ST, Kwok E, You Z, Rubery PT, Dougherty PE, Hilton MJ, Awad HA, Schwarz EM. Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularity. J Orthop Res. 2010 Sep; 28(9):1220-8.
    View in: PubMed
  8. Rubery PT. Enhancing allograft bone healing through gene therapy. Spine (Phila Pa 1976). 2010 Aug 1; 35(17):1640-7.
    View in: PubMed
  9. Rubery PT, Bukata SV. Teriparatide may accelerate healing in delayed unions of type III odontoid fractures: a report of 3 cases. J Spinal Disord Tech. 2010 Apr; 23(2):151-5.
    View in: PubMed
  10. Brandenstein D, Molinari RW, Rubery PT, Rechtine GR. Unstable subaxial cervical spine injury with normal computed tomography and magnetic resonance initial imaging studies: a report of four cases and review of the literature. Spine (Phila Pa 1976). 2009 Sep 15; 34(20):E743-50.
    View in: PubMed
  11. Perlmutter DH, Campbell S, Rubery PT, Vates EG, Silberstein HJ. Aneurysmal bone cyst: surgical management in the pediatric cervical spine. Spine (Phila Pa 1976). 2009 Jan 1; 34(1):E50-3.
    View in: PubMed
  12. Andersson GB, Bridwell KH, Danielsson A, Dolan LA, Everett CR, Fisher CG, Mercado E, Mulpuri K, Richards BS, Rubery PT, Sponseller PD, Weinstein JN. Evidence-based medicine summary statement. Spine (Phila Pa 1976). 2007 Sep 1; 32(19 Suppl):S64-5.
    View in: PubMed
  13. Reynolds DG, Hock C, Shaikh S, Jacobson J, Zhang X, Rubery PT, Beck CA, O'keefe RJ, Lerner AL, Schwarz EM, Awad HA. Micro-computed tomography prediction of biomechanical strength in murine structural bone grafts. J Biomech. 2007; 40(14):3178-86.
    View in: PubMed
  14. Xie C, Reynolds D, Awad H, Rubery PT, Pelled G, Gazit D, Guldberg RE, Schwarz EM, O'Keefe RJ, Zhang X. Structural bone allograft combined with genetically engineered mesenchymal stem cells as a novel platform for bone tissue engineering. Tissue Eng. 2007 Mar; 13(3):435-45.
    View in: PubMed
  15. Maloney MD, Goater JJ, Parsons R, Ito H, O'Keefe RJ, Rubery PT, Drissi MH, Schwarz EM. Safety and efficacy of ultraviolet-a light-activated gene transduction for gene therapy of articular cartilage defects. J Bone Joint Surg Am. 2006 Apr; 88(4):753-61.
    View in: PubMed
  16. Zhang X, Xie C, Lin AS, Ito H, Awad H, Lieberman JR, Rubery PT, Schwarz EM, O'Keefe RJ, Guldberg RE. Periosteal progenitor cell fate in segmental cortical bone graft transplantations: implications for functional tissue engineering. J Bone Miner Res. 2005 Dec; 20(12):2124-37.
    View in: PubMed
  17. Koefoed M, Ito H, Gromov K, Reynolds DG, Awad HA, Rubery PT, Ulrich-Vinther M, Soballe K, Guldberg RE, Lin AS, O'Keefe RJ, Zhang X, Schwarz EM. Biological effects of rAAV-caAlk2 coating on structural allograft healing. Mol Ther. 2005 Aug; 12(2):212-8.
    View in: PubMed
  18. Ito H, Koefoed M, Tiyapatanaputi P, Gromov K, Goater JJ, Carmouche J, Zhang X, Rubery PT, Rabinowitz J, Samulski RJ, Nakamura T, Soballe K, O'Keefe RJ, Boyce BF, Schwarz EM. Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy. Nat Med. 2005 Mar; 11(3):291-7.
    View in: PubMed
  19. Tiyapatanaputi P, Rubery PT, Carmouche J, Schwarz EM, O'keefe RJ, Zhang X. A novel murine segmental femoral graft model. J Orthop Res. 2004 Nov; 22(6):1254-60.
    View in: PubMed
  20. Lustik SJ, Papadakos PJ, Jackman KV, Rubery PT, Kaplan KL, Chhibber AK. Nicardipine versus nitroprusside for deliberate hypotension during idiopathic scoliosis repair. J Clin Anesth. 2004 Feb; 16(1):25-33.
    View in: PubMed
  21. Ito H, Goater JJ, Tiyapatanaputi P, Rubery PT, O'Keefe RJ, Schwarz EM. Light-activated gene transduction of recombinant adeno-associated virus in human mesenchymal stem cells. Gene Ther. 2004 Jan; 11(1):34-41.
    View in: PubMed
  22. Patel RK, Rubery PT, Myers S, Everett CR. Pedicle lesion in the toddler: a radiologic review. Pain Physician. 2003 Apr; 6(2):213-6.
    View in: PubMed
  23. Rubery PT, Bradford DS. Athletic activity after spine surgery in children and adolescents: results of a survey. Spine (Phila Pa 1976). 2002 Feb 15; 27(4):423-7.
    View in: PubMed
  24. Rubery PT, Smith MD, Cammisa FP, Silane M. Mycotic aortic aneurysm in patients who have lumbar vertebral osteomyelitis. A report of two cases. J Bone Joint Surg Am. 1995 Nov; 77(11):1729-32.
    View in: PubMed
  25. Rubery PT, Spielman JH, Hester P, Axelrod E, Burke SW, Levine DB. Scoliosis in familial dysautonomia. Operative treatment. J Bone Joint Surg Am. 1995 Sep; 77(9):1362-9.
    View in: PubMed

Visualizations


Rubery's Networks

Concepts
_
Co-Authors
_
Similar People
_
Same Department