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William Drucker

TitleProfessor Emeritus
InstitutionSchool of Medicine and Dentistry
DepartmentSurgery
AddressUSUHS School of Medicine
4301 Jones Bridge Road
Bethesda MD 20814
 
 Selected Publications
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  1. Gann DS, Drucker WR. Hemorrhagic shock. J Trauma Acute Care Surg. 2013 Nov; 75(5):888-95.
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  2. Drucker W. The use and abuse of shock models. J Trauma. 2009 Oct; 67(4):865-6.
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  3. Pearce FJ, Waasdorp C, Hufnagel H, Burris D, DeFeo J, Soballe P, Drucker WR. Subcutaneous PO2 as an index of the physiological limits for hemodilution in the rat. J Appl Physiol. 2005 Sep; 99(3):814-21.
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  4. Drucker WR. Stone soup as concocted by Professor Norman Rich. World J Surg. 2005; 29 Suppl 1:S46-9.
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  5. Soballe PW, Nimbkar NV, Hayward I, Nielsen TB, Drucker WR. Electric cautery lowers the contamination threshold for infection of laparotomies. Am J Surg. 1998 Apr; 175(4):263-6.
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  6. Lukish JR, Muro K, DeNobile J, Katz R, Williams J, Cruess DF, Drucker W, Kirsch I, Hamilton SR. Prognostic significance of DNA replication errors in young patients with colorectal cancer. Ann Surg. 1998 Jan; 227(1):51-6.
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  7. Drucker W, Pearce F, Glass-Heidenreich L, Hopf H, Powell C, Ochsner MG, Frankel H, Murray D, Nelson M, Champion H, Rozycki G, Silva J, Malcolm D, DeNobile J, Harviel D, Rich N, Hunt TK. Subcutaneous tissue oxygen pressure: a reliable index of peripheral perfusion in humans after injury. J Trauma. 1996 Mar; 40(3 Suppl):S116-22.
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  8. Powell CC, Schultz SC, Burris DG, Drucker WR, Malcolm DS. Subcutaneous oxygen tension: a useful adjunct in assessment of perfusion status. Crit Care Med. 1995 May; 23(5):867-73.
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  9. Ochsner MG, Herr D, Drucker W, Champion HR. A modified Seldinger technique for peritoneal lavage in trauma patients who are obese. Surg Gynecol Obstet. 1991 Aug; 173(2):158-60.
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  10. MacGillivray DC, Synder DA, Drucker W, ReMine SG. Carcinoid tumors: the relationship between clinical presentation and the extent of disease. Surgery. 1991 Jul; 110(1):68-72.
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  11. Kumar A, Murray DL, Hanna CB, Kreindler TG, Jacobson KD, Bundy JM, Waxman K, Finnerty EF, Folan DW, Drucker WR, et al. Comparative study of cephalexin hydrochloride and cephalexin monohydrate in the treatment of skin and soft tissue infections. Antimicrob Agents Chemother. 1988 Jun; 32(6):882-5.
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  12. Pearce FJ, Drucker WR. Glucose infusion arrests the decompensatory phase of hemorrhagic shock. J Trauma. 1987 Nov; 27(11):1213-20.
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  13. McEnroe CS, Pearce FJ, Ricotta JJ, Drucker WR. Failure of oxygen-free radical scavengers to improve postischemic liver function. J Trauma. 1986 Oct; 26(10):892-6.
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  14. Connett RJ, Pearce FJ, Drucker WR. Scaling of physiological responses: a new approach for hemorrhagic shock. Am J Physiol. 1986 Jun; 250(6 Pt 2):R951-9.
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  15. Pearce FJ, Connett RJ, Drucker WR. Phase-related changes in tissue energy reserves during hemorrhagic shock. J Surg Res. 1985 Nov; 39(5):390-8.
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  16. Pearce FJ, Connett RJ, Drucker WR. Extracellular-intracellular lactate gradients in skeletal muscle during hemorrhagic shock in the rat. Surgery. 1985 Oct; 98(4):625-31.
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  17. Chadwick CD, Pearce FJ, Drucker WR. Influences of fasting and water intake on plasma refill during hemorrhagic shock. J Trauma. 1985 Jul; 25(7):608-14.
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  18. Drucker WR, Gavett WJ. Cost containment and survival of the teaching hospital. Am J Surg. 1985 Mar; 149(3):315-6.
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  19. Drucker WR. The management of trauma: imperatives for hospital cost containment. Bull Am Coll Surg. 1984 Oct; 69(10):12-9.
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  20. Pass LJ, Schloerb PR, Pearce FJ, Drucker WR. Cardiopulmonary response of the rat to gram-negative bacteremia. Am J Physiol. 1984 Mar; 246(3 Pt 2):H344-50.
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  21. Drucker WR, Gavett JW, Kirshner R, Messick WJ, Ingersoll G. Toward strategies for cost containment in surgical patients. Ann Surg. 1983 Sep; 198(3):284-300.
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  22. Pearce FJ, Weiss PR, Miller JR, Drucker WR. Effect of hemorrhage and anoxia on hepatic gluconeogenesis and potassium balance in the rat. J Trauma. 1983 Apr; 23(4):312-6.
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  23. Pass LJ, Schloerb PR, Chow FT, Graham M, Pearce FJ, Franklin MW, Drucker WR. Liver adenosine triphosphate (ATP) in hypoxia and hemorrhagic shock. J Trauma. 1982 Sep; 22(9):730-5.
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  24. Friedman SG, Pearce FJ, Drucker WR. The role of blood glucose in defense of plasma volume during hemorrhage. J Trauma. 1982 Feb; 22(2):86-91.
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  25. Swerlick RA, Drucker NA, McCoy S, Pearce FJ, Drucker WR. Insulin effectiveness in hypovolemic dogs. J Trauma. 1981 Dec; 21(12):1013-21.
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  26. Drucker WR, Chadwick CD, Gann DS. Transcapillary refill in hemorrhage and shock. Arch Surg. 1981 Oct; 116(10):1344-53.
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  27. Longnecker DE, McCoy S, Drucker WR. Anesthetic influence on response to hemorrhage in rats. Circ Shock. 1979; 6(1):55-60.
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  28. Anderson KV, Bleyl KL, Drucker WR. Peripheral uptake of glucose during sepsis. Surg Forum. 1979; 30:40-1.
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  29. McCoy S, Case SA, Swerlick RA, Bailey AA, Drucker WR. Determinants of blood amino acid concentration after hemorrhage. Am Surg. 1977 Dec; 43(12):787-93.
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  30. Drucker WR. A consideration of undergraduate surgical education by university administrators who are surgeons: a curriculum for all physicians. Bull Am Coll Surg. 1977 Jun; 62(6):16-7.
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  31. Stone JP, Schutzer SF, McCoy S, Drucker WR. Contribution of glucose to the hyperosmolality of prolonged hypovolemia. Am Surg. 1977 Jan; 43(1):1-5.
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  32. Lau TS, McMillan N, Cherrington A, Lo S, Drucker WR, Koven IH. Insulin metabolism in depancreatized dogs during hemorrhagic shock. J Surg Oncol. 1976; 8(1):49-52.
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  33. Shearburn EW, Craig WD, Maitland CL, Howard PL, McCoy S, Drucker WR. Hemodynamic and metabolic alterations in peripheral tissue during hemorrhagic shock. Am Surg. 1975 Nov; 41(11):696-703.
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  34. Drucker WR. William Douglas Holden: surgical Socrates. Am J Surg. 1975 Nov; 130(5):504-7.
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  35. Drucker WR, Howard PL, McCoy S. The influence of diet on response to hemorrhagic shock. Ann Surg. 1975 May; 181(5):698-704.
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  36. Heimbecker RO, Lemire G, Koven I, Richards K, Drucker WR. The role of gas embolism in decompression sickness. Bibl Anat. 1973; 11:488-94.
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  37. Lau TS, McMillan N, Cherrington A, Lo S, Drucker WR, Koven IH. Insulin metabolism in depancreatized dogs during hemorrhagic shock. Surg Forum. 1973; 24:94-6.
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  38. Drucker WR. Charles B. Huggins, MD, FACS (hon). Surg Forum. 1973; 24:V.
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  39. Lau TS, Taubenfligel W, Levene R, Farago G, Chan H, Koven I, Drucker WR. Pancreatic blood flow and insulin output in severe hemorrhage. J Trauma. 1972 Oct; 12(10):880-4.
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  40. Drucker WR, Gallie BL, Lau TS, Farago G, Levene RA, Haist RE. The effect of persisting hypovolemic shock on pancreatic output of insulin. Adv Exp Med Biol. 1972; 33(0):187-98.
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  41. Vigas M, Haist RE, Bauer F, Drucker WR. Insulin secretion during hemorrhagic shock. Adv Exp Med Biol. 1972; 33(0):179-86.
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  42. Izsak EM, Lau TS, Koven EH, Drucker WR. Capillary outflow phenomena in late hemorrhagic shock. Surg Forum. 1972; 23(0):8-10.
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  43. Richards KU, Durnford B, Heimbecker RO, JeeJeeBhoy KN, Colapinto R, Drucker WR. Transient functional aberrations in experimental celiac axis compression syndrome. Surg Forum. 1972; 23(0):390-1.
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  44. Vigas M, Haist RE, Bauer F, Drucker WR. Insulin secretion during hemorrhagic shock in dogs. Endocrinol Exp. 1972; 6(4):231-7.
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  45. Cotton RT, Mugashe RL, Gallie BL, Chan H, Koven IH, Drucker WR. Measurement of cardiac output in rats by 125 I dilution. Can J Physiol Pharmacol. 1971 Dec; 49(12):1019-22.
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  46. Waddell JP, Drucker WR. Occult injuries in pedestrian accidents. J Trauma. 1971 Oct; 11(10):844-52.
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  47. Drucker WR. Shock and metabolism. Surg Gynecol Obstet. 1971 Feb; 132(2):234-9.
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  48. Gallie BL, Koven IH, Taubenfligel V, Drucker WR. Correction of the interstitial diffusion defect in hemorrhagic shock by balanced salt solution. Surg Forum. 1971; 22:21-2.
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  49. Farago G, Levene RA, Lau TS, Drucker WR. Availability of lipid for energy metabolism during hypovolemia. Surg Forum. 1971; 22:7-9.
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  50. Lau TS, Levene RA, Farago G, Drucker WR. Pancreatic output of insulin in response to hemorrhagic shock. Surg Forum. 1971; 22:73-5.
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  51. Egdahl RH, Drucker WR. Trauma workshop report: endocrine response. J Trauma. 1970 Nov; 10(11):1050-1.
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  52. Drucker WR, Drapanas T. Trauma workshop report: liver and pancreas in injury. J Trauma. 1970 Nov; 10(11):1087-8.
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  53. Lemire GG, Heimbecker RO, Chen C, Drucker WR. [Caisson disease: new etiology]. Union Med Can. 1970 Oct; 99(10):1809-12.
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  54. Drucker WR, Jeejeebhoy KN. Azathioprine: an adjunct to surgical therapy of granulomatous enteritis. Ann Surg. 1970 Oct; 172(4):618-26.
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  55. Koven IH, Acemoglu M, Ledger D, Lo SF, Cotton R, Drucker WR. Changes produced by hemorrhagic shock in the transport characteristics of interstitial fluid. Surg Forum. 1970; 21:36-7.
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  56. Drucker WR, Vigas SN, Bauer FE, Haist RE, Heimbecker RO. Tolerance to prolonged hypovolaemic shock: the effect of infusion of an energy substrate. Br J Surg. 1969 Sep; 56(9):704.
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  57. Heimbecker RO, Drucker WR, Levene MR, Lemire G. Surgery for acute myocardial infarction: an experimental study of emergency infarctectomy with a preliminary report on the clinical application. Br J Surg. 1969 Aug; 56(8):614.
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  58. Bauer WE, Vigas SN, Haist RE, Drucker WR. Insulin response during hypovolemic shock. Surgery. 1969 Jul; 66(1):80-8.
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  59. Bauer WE, Levene RA, Zachwieja A, Lee MJ, Menczyk Z, Drucker WR. The role of catecholamines in energy metabolism during prolonged hemorrhagic shock. Surg Forum. 1969; 20:9-11.
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  60. Pearson FG, Stone RM, Parrish RM, Falk RE, Drucker WR. Role of vagotomy and pyloroplasty in the therapy of symptomatic hiatus hernia. Am J Surg. 1969 Jan; 117(1):130-7.
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  61. Heimbecker RO, Lemire G, Chen CH, Koven I, Leask D, Drucker WR. Role of gas embolism in decompression sickness--a new look at "the bends". Surgery. 1968 Jul; 64(1):264-72.
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  62. Drucker WR, Schlatter J, Drucker RP. Metabolic factors associated with endotoxin-induced tolerance for hemorrhagic shock. Surgery. 1968 Jul; 64(1):75-84.
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  63. DePalma RG, Drucker WR, Levey S, Polster DF, Holden WD. Histochemical investigation of hepatic adenosine triphosphatase and glucose-6-phosphatase activity in hemorrhagic shock. Proc Soc Exp Biol Med. 1968 Apr; 127(4):1090-4.
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  64. David R, Golan S, Drucker W. Familial aldosterone deficiency: enzyme defect, diagnosis, and clinical course. Pediatrics. 1968 Feb; 41(2):403-12.
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  65. Moffat JG, King JA, Drucker WR. Tolerance to prolonged hypovolemic shock: effect of infusion of an energy substrate. Surg Forum. 1968; 19:5-8.
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  66. King JA, Levine R, Recknagel FO, Drucker WR. The metabolic effect of hemorrhagic shock on preexisting respiratory alkalosis. Surg Forum. 1968; 19:40-2.
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  67. Schmidt GH, Drucker WR. Effect of hemorrhagic shock on wound healing in rats and guinea pigs. J Surg Res. 1967 Nov; 7(11):513-9.
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  68. Miller RC, Sterioff S, Drucker WR, Persky L, Wright HK, Davis JH. The incidental discovery of occult abdominal tumors in children following blunt abdominal trauma. J Trauma. 1966 Jan; 6(1):99-106.
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  69. Holden WD, DePalma RG, Drucker WR, McKalen A. Ultrastructural changes in hemorrhagic shock. Electron microscopic study of liver, kidney and striated muscle cells in rats. Ann Surg. 1965 Sep; 162(3):517-36.
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  70. HINZ CF, DRUCKER WR, LARNER J. IDIOPATHIC MYOGLOBINURIA; METABOLIC AND ENZYMATIC STUDIES ON THREE PATIENTS. Am J Med. 1965 Jul; 39:49-57.
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  71. DRUCKER WR, DAVIS HS, BURGET D, POWERS AL, SIEVERDING R. EFFECT OF HALOTHANE AND CYCLOPROPANE ANESTHESIA ON ENERGY METABOLISM IN HYPOVOLEMIC ANIMALS. J Trauma. 1965 Jul; 5:503-14.
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  72. Coffin LH, Gann DS, Drucker WR. Valsalva's maneuver: an index of effective circulatory volume. Surg Forum. 1965; 16:38-9.
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  73. IZANT RJ, DRUCKER WR. DUODENAL OBSTRUCTION DUE TO INTRAMURAL HEMATOMA IN CHILDREN. J Trauma. 1964 Nov; 4:797-813.
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  74. DRUCKER WR, DAVIS JH, HOLDEN WD, REAGAN JR. HEMORRHAGIC NECROSIS OF THE INTESTINE. A CLINICAL SYNDROME: PRESENCE WITHOUT ORGANIC VASCULAR OCCLUSION. Arch Surg. 1964 Jul; 89:42-53.
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  75. Drucker WR, Wright HK. Physiology and pathophysiology of gastrointestinal fluids. Curr Probl Surg. 1964 May; 1-72.
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  76. DRUCKER WR, DEKIEWIET JC. GLUCOSE UPTAKE BY DIAPHRAGMS FROM RATS SUBJECTED TO HEMORRHAGIC SHOCK. Am J Physiol. 1964 Feb; 206:317-20.
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  77. WRIGHT HK, MCMASTER W, GANN DS, DRUCKER WR. CORRECTION OF THE RENAL CONCENTRATING DEFECT IN HEMORRHAGIC SHOCK. Surg Forum. 1964; 15:18-20.
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  78. DRUCKER WR, KINGSBURY B, GRAHAM L. The effect of hypothermia on intermediary metabolism. Metabolism. 1962 Oct; 11:1087-97.
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  79. GANN DS, KINGSBURY B, DRUCKER WR, TRAVIS RH. Diminished adrenal corticoid response to burn and ACTH in the nephrectomizekdog. Proc Soc Exp Biol Med. 1961 Oct; 108:99-103.
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  80. DRUCKER WR, CRAIG JW, HUBAY CA, DAVIS JH, WOODWARD H. The metbolic effects of trauma to denervated tissue in man. J Trauma. 1961 May; 1:306-21.
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  81. CRAIG JW, DRUCKER WR, MILLER M, WOODWARD H. A prompt effect of exogenous insulin on net hepatic glucose output in man. Metabolism. 1961 Mar; 10:212-20.
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  82. DRUCKER WR, KINGSBURY B, CRAIG JW, HOFMANN N, WOODWARD H. Investigation of aerobic metabolism in surgical patients: citrate tolerance studies. Surg Forum. 1961; 12:3-5.
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  83. DRUCKER WR. The influence of hypothermia on metabolism during hemorrhagic shock. Surg Forum. 1960; 11:136-8.
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  84. KRIEGER H, LEVEY S, DRUCKER WR, ABBOTT WE. A study of the metabolic response to surgery in paraplegics. Surg Forum. 1960; 11:475-7.
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  85. DRUCKER WR, COSTLEY C, STULTS R, HOLDEN WD, CRAIG J, MILLER M, HOFMANN N, WOODWARD H. Studies of carbohydrate metabolism during ether anesthesia. I. Effect of ether on glucose and fructose metabolism. Metabolism. 1959 Nov; 8:827-46.
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  86. CRAIG JW, MILLER M, DRUCKER WR, WOODWARD H. Influence of dietary fructose on glucose tolerance in man. Diabetes. 1959 Nov-Dec; 8:432-7.
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  87. LEVEY S, DRUCKER WR, CZARNECKI N. Energy expenditure of surgeons, nurses, and anesthesiologists during operative procedures. Surgery. 1959 Sep; 46:529-33.
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  88. DRUCKER WR, HUBAY CA, HOLDEN WD, BUKOVNIC JA. Pathogenesis of post-traumatic sympathetic dystrophy. Am J Surg. 1959 Apr; 97(4):454-65.
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  89. CRAIG JW, DRUCKER WR, MILLER M, WOODWARD H, MOLZAHN V. A comparison of the influence of tolbutamide and small doses of insulin on the splanchnic output and peripheral uptake of glucose in man. Ann N Y Acad Sci. 1959 Mar 30; 74(3):537-47.
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  90. DRUCKER WR, KAYE M, KENDRICK R, HOFMANN N, KINGSBURY B. Metabolic aspects of hemorrhagic shock. I. Changes in intermediary metabolism during hemorrhage and repletion of blood. Surg Forum. 1958; 9:49-54.
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  91. MILLER M, CRAIG JW, MACKENZIE MS, DRUCKER WR, CAMMARN MW, WOODWARD H. Studies of the effect of intravenous tolbutamide on pyruvic and lactic acid concentrations in peripheral venous blood in normal and diabetic subjects, and on splanchnic metabolism of fructose and glucose. Ann N Y Acad Sci. 1957 Jul 10; 71(1):51-61.
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  92. HUBAY CA, KIEHN CC, DRUCKER WR. Surgical management of decubitus ulcers in the post-traumatic patient. Am J Surg. 1957 Apr; 93(4):705-13.
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  93. DRUCKER WR, STULTS R, COSTLEY C, DOCKERY J, HOLDEN WD. The effect of anesthesia on blood volume and osmotic pressure. Surg Forum. 1957; 7:189-92.
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  94. DRUCKER WR, COSTLEY C, STULTS R, MILLER M, CRAIG JW, WOODWARD H. The effect of ether anesthesia on pyruvate metabolism. Surg Forum. 1957; 7:185-8.
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  95. MILLER M, CRAIG JW, DRUCKER WR, WOODWARD H. The metabolism of fructose in man. Yale J Biol Med. 1956 Dec; 29(3):335-60.
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  96. DRUCKER W, KRIEGER H, BABB LI, LEVEY S, ABBOTT WE. Metabolic alterations in surgical patients. II. The excretion of salt and water postoperatively following the administration of various sodium-containing solutions. Surg Forum. 1953 Oct; 4:544-53.
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  97. DRUCKER WR, MILLER M, CRAIG J, JEFFERIES WM, LEVEY S, ABBOTT WE. A comparison of the effect of operation on glucose and fructose metabolism. Surg Forum. 1953; (38th Congress):548-55.
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  98. MILLER M, DRUCKER WR, OWENS JE, CRAIG JW, WOODWARD H. Metabolism of intravenous fructose and glucose in normal and diabetic subjects. J Clin Invest. 1952 Jan; 31(1):115-25.
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  99. CRAIG JW, DRUCKER WR, MILLER M, OWENS JE, WOODWARD H, BROFMAN B, PRITCHARD WH. Metabolism of fructose by the liver of diabetic and nondiabetic subjects. Proc Soc Exp Biol Med. 1951 Dec; 78(3):698-702.
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