Peter Keng
| Title | Professor Emeritus |
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| Institution | School of Medicine and Dentistry |
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| Department | Radiation Oncology |
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| Address | University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 704
Rochester NY 14642
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O'Reilly MA, Yee M, Buczynski BW, Vitiello PF, Keng PC, Welle SL, Finkelstein JN, Dean DA, Lawrence BP. Neonatal oxygen increases sensitivity to influenza a virus infection in adult mice by suppressing epithelial expression of ear1. Am J Pathol. 2012 Aug; 181(2):441-51.
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Chiu YH, Mensah KA, Schwarz EM, Ju Y, Takahata M, Feng C, McMahon LA, Hicks DG, Panepento B, Keng PC, Ritchlin CT. Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP). J Bone Miner Res. 2012 Jan; 27(1):79-92.
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Zhang M, Swarts SG, Yin L, Liu C, Tian Y, Cao Y, Swarts M, Yang S, Zhang SB, Zhang K, Ju S, Olek DJ, Schwartz L, Keng PC, Howell R, Zhang L, Okunieff P. Antioxidant properties of quercetin. Adv Exp Med Biol. 2011; 701:283-9.
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Chen Y, Pandya KJ, Hyrien O, Keng PC, Smudzin T, Anderson J, Qazi R, Smith B, Watson TJ, Feins RH, Johnstone DW. Preclinical and pilot clinical studies of docetaxel chemoradiation for Stage III non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2011 Aug 1; 80(5):1358-64.
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Zhang L, Sun W, Wang J, Zhang M, Yang S, Tian Y, Vidyasagar S, Peña LA, Zhang K, Cao Y, Yin L, Wang W, Zhang L, Schaefer KL, Saubermann LJ, Swarts SG, Fenton BM, Keng PC, Okunieff P. Mitigation effect of an FGF-2 peptide on acute gastrointestinal syndrome after high-dose ionizing radiation. Int J Radiat Oncol Biol Phys. 2010 May 1; 77(1):261-8.
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Krance SM, Keng PC, Palis J, Ballatori N. Transient glutathione depletion determines terminal differentiation in HL-60 cells. Oxid Med Cell Longev. 2010 Jan-Feb; 3(1):53-60.
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Tsai CH, Chiu SJ, Liu CC, Sheu TJ, Hsieh CH, Keng PC, Lee YJ. Regulated expression of cofilin and the consequent regulation of p27(kip1) are essential for G(1) phase progression. Cell Cycle. 2009 Aug; 8(15):2365-74.
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Zhang H, Zhang SB, Sun W, Yang S, Zhang M, Wang W, Liu C, Zhang K, Swarts S, Fenton BM, Keng P, Maguire D, Okunieff P, Zhang L. B1 sequence-based real-time quantitative PCR: a sensitive method for direct measurement of mouse plasma DNA levels after gamma irradiation. Int J Radiat Oncol Biol Phys. 2009 Aug 1; 74(5):1592-9.
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Chuang KH, Altuwaijri S, Li G, Lai JJ, Chu CY, Lai KP, Lin HY, Hsu JW, Keng P, Wu MC, Chang C. Neutropenia with impaired host defense against microbial infection in mice lacking androgen receptor. J Exp Med. 2009 May 11; 206(5):1181-99.
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Lee YJ, Tsai CH, Hwang JJ, Chiu SJ, Sheu TJ, Keng PC. Involvement of a p53-independent and post-transcriptional up-regulation for p21WAF/CIP1 following destabilization of the actin cytoskeleton. Int J Oncol. 2009 Feb; 34(2):581-9.
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Zhang H, Maguire D, Swarts S, Sun W, Yang S, Wang W, Liu C, Zhang M, Zhang D, Zhang L, Zhang K, Keng P, Zhang L, Okunieff P. Replication of murine mitochondrial DNA following irradiation. Adv Exp Med Biol. 2009; 645:43-8.
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Zhang H, Hyrien O, Pandya KJ, Keng PC, Chen Y. Tumor response kinetics after schedule-dependent paclitaxel chemoradiation treatment for inoperable non-small cell lung cancer: a model for low-dose chemotherapy radiosensitization. J Thorac Oncol. 2008 Jun; 3(6):563-8.
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Gehen SC, Staversky RJ, Bambara RA, Keng PC, O'Reilly MA. hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress. Oncogene. 2008 Jul 3; 27(29):4065-74.
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Hahn MA, Keng PC, Krauss TD. Flow cytometric analysis to detect pathogens in bacterial cell mixtures using semiconductor quantum dots. Anal Chem. 2008 Feb 1; 80(3):864-72.
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Sun W, Wang W, Kim J, Keng P, Yang S, Zhang H, Liu C, Okunieff P, Zhang L. Anti-cancer effect of resveratrol is associated with induction of apoptosis via a mitochondrial pathway alignment. Adv Exp Med Biol. 2008; 614:179-86.
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Okunieff P, Swarts S, Keng P, Sun W, Wang W, Kim J, Yang S, Zhang H, Liu C, Williams JP, Huser AK, Zhang L. Antioxidants reduce consequences of radiation exposure. Adv Exp Med Biol. 2008; 614:165-78.
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Chen Y, Pandya KJ, Feins R, Johnstone DW, Watson T, Smudzin T, Keng PC. Toxicity profile and pharmacokinetic study of a phase I low-dose schedule-dependent radiosensitizing paclitaxel chemoradiation regimen for inoperable non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2008 Jun 1; 71(2):407-13.
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Vitiello PF, Staversky RJ, Keng PC, O'Reilly MA. PUMA inactivation protects against oxidative stress through p21/Bcl-XL inhibition of bax death. Free Radic Biol Med. 2008 Feb 1; 44(3):367-74.
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Wang W, Yang S, Su Y, Xiao Z, Wang C, Li X, Lin L, Fenton BM, Paoni SF, Ding I, Keng P, Okunieff P, Zhang L. Enhanced antitumor effect of combined triptolide and ionizing radiation. Clin Cancer Res. 2007 Aug 15; 13(16):4891-9.
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Dertinger SD, Tsai Y, Nowak I, Hyrien O, Sun H, Bemis JC, Torous DK, Keng P, Palis J, Chen Y. Reticulocyte and micronucleated reticulocyte responses to gamma irradiation: dose-response and time-course profiles measured by flow cytometry. Mutat Res. 2007 Dec 1; 634(1-2):119-25.
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Ghosh A, Keng PC, Knauf PA. Hypertonicity induced apoptosis in HL-60 cells in the presence of intracellular potassium. Apoptosis. 2007 Jul; 12(7):1281-8.
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Gehen SC, Vitiello PF, Bambara RA, Keng PC, O'Reilly MA. Downregulation of PCNA potentiates p21-mediated growth inhibition in response to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2007 Mar; 292(3):L716-24.
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Brandt PD, Helt CE, Keng PC, Bambara RA. The Rad9 protein enhances survival and promotes DNA repair following exposure to ionizing radiation. Biochem Biophys Res Commun. 2006 Aug 18; 347(1):232-7.
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Staversky RJ, Vitiello PF, Gehen SC, Helt CE, Rahman A, Keng PC, O'Reilly MA. p21(Cip1/Waf1/Sdi1) protects against hyperoxia by maintaining expression of Bcl-X(L). Free Radic Biol Med. 2006 Aug 15; 41(4):601-9.
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Yao Z, Li P, Zhang Q, Schwarz EM, Keng P, Arbini A, Boyce BF, Xing L. Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression. J Biol Chem. 2006 Apr 28; 281(17):11846-55.
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Chen MF, Keng PC, Shau H, Wu CT, Hu YC, Liao SK, Chen WC. Inhibition of lung tumor growth and augmentation of radiosensitivity by decreasing peroxiredoxin I expression. Int J Radiat Oncol Biol Phys. 2006 Feb 1; 64(2):581-91.
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Tsai MH, Chen X, Chandramouli GV, Chen Y, Yan H, Zhao S, Keng P, Liber HL, Coleman CN, Mitchell JB, Chuang EY. Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells. Oncogene. 2006 Jan 26; 25(4):622-32.
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Chen MF, Keng PC, Lin PY, Yang CT, Liao SK, Chen WC. Caffeic acid phenethyl ester decreases acute pneumonitis after irradiation in vitro and in vivo. BMC Cancer. 2005; 5:158.
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Mao W, Iwai C, Keng PC, Vulapalli R, Liang CS. Norepinephrine-induced oxidative stress causes PC-12 cell apoptosis by both endoplasmic reticulum stress and mitochondrial intrinsic pathway: inhibition of phosphatidylinositol 3-kinase survival pathway. Am J Physiol Cell Physiol. 2006 May; 290(5):C1373-84.
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Lee YJ, Mazzatti DJ, Yun Z, Keng PC. Inhibition of invasiveness of human lung cancer cell line H1299 by over-expression of cofilin. Cell Biol Int. 2005 Nov; 29(11):877-83.
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Lee YJ, Sheu TJ, Keng PC. Enhancement of radiosensitivity in H1299 cancer cells by actin-associated protein cofilin. Biochem Biophys Res Commun. 2005 Sep 23; 335(2):286-91.
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Lee YJ, Keng PC. Studying the effects of actin cytoskeletal destabilization on cell cycle by cofilin overexpression. Mol Biotechnol. 2005 Sep; 31(1):1-10.
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Helt CE, Wang W, Keng PC, Bambara RA. Evidence that DNA damage detection machinery participates in DNA repair. Cell Cycle. 2005 Apr; 4(4):529-32.
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McCollum G, Keng PC, States JC, McCabe MJ. Arsenite delays progression through each cell cycle phase and induces apoptosis following G2/M arrest in U937 myeloid leukemia cells. J Pharmacol Exp Ther. 2005 May; 313(2):877-87.
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Mazzatti DJ, Lee YJ, Helt CE, O'Reilly MA, Keng PC. p53 modulates radiation sensitivity independent of p21 transcriptional activation. Am J Clin Oncol. 2005 Feb; 28(1):43-50.
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Helt CE, Cliby WA, Keng PC, Bambara RA, O'Reilly MA. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage. J Biol Chem. 2005 Jan 14; 280(2):1186-92.
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Chen MF, Wu CT, Chen YJ, Keng PC, Chen WC. Cell killing and radiosensitization by caffeic acid phenethyl ester (CAPE) in lung cancer cells. J Radiat Res (Tokyo). 2004 Jun; 45(2):253-60.
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Wang L, Hsu CL, Ni J, Wang PH, Yeh S, Keng P, Chang C. Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells. Mol Cell Biol. 2004 Mar; 24(5):2202-13.
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Mao W, Qin F, Iwai C, Vulapalli R, Keng PC, Liang CS. Extracellular norepinephrine reduces neuronal uptake of norepinephrine by oxidative stress in PC12 cells. Am J Physiol Heart Circ Physiol. 2004 Jul; 287(1):H29-39.
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Abeysinghe HR, Pollock SJ, Guckert NL, Veyberman Y, Keng P, Halterman M, Federoff HJ, Rosenblatt JP, Wang N. The role of the THY1 gene in human ovarian cancer suppression based on transfection studies. Cancer Genet Cytogenet. 2004 Feb; 149(1):1-10.
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Roper JM, Mazzatti DJ, Watkins RH, Maniscalco WM, Keng PC, O'Reilly MA. In vivo exposure to hyperoxia induces DNA damage in a population of alveolar type II epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2004 May; 286(5):L1045-54.
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Helt CE, Staversky RJ, Lee YJ, Bambara RA, Keng PC, O'Reilly MA. The Cdk and PCNA domains on p21Cip1 both function to inhibit G1/S progression during hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2004 Mar; 286(3):L506-13.
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Liu W, Chen Y, Wang W, Keng P, Finkelstein J, Hu D, Liang L, Guo M, Fenton B, Okunieff P, Ding I. Combination of radiation and celebrex (celecoxib) reduce mammary and lung tumor growth. Am J Clin Oncol. 2003 Aug; 26(4):S103-9.
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Abeysinghe HR, Cao Q, Xu J, Pollock S, Veyberman Y, Guckert NL, Keng P, Wang N. THY1 expression is associated with tumor suppression of human ovarian cancer. Cancer Genet Cytogenet. 2003 Jun; 143(2):125-32.
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Roper JM, Staversky RJ, Finkelstein JN, Keng PC, O'Reilly MA. Identification and isolation of mouse type II cells on the basis of intrinsic expression of enhanced green fluorescent protein. Am J Physiol Lung Cell Mol Physiol. 2003 Sep; 285(3):L691-700.
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Chen Y, Pandya K, Keng PC, Johnstone D, Li J, Lee YJ, Smudzin T, Okunieff P. Phase I/II clinical study of pulsed paclitaxel radiosensitization for thoracic malignancy: a therapeutic approach on the basis of preclinical research of human cancer cell lines. Clin Cancer Res. 2003 Mar; 9(3):969-75.
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Xing L, Carlson L, Story B, Tai Z, Keng P, Siebenlist U, Boyce BF. Expression of either NF-kappaB p50 or p52 in osteoclast precursors is required for IL-1-induced bone resorption. J Bone Miner Res. 2003 Feb; 18(2):260-9.
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O'Reilly MA, Staversky RJ, Finkelstein JN, Keng PC. Activation of the G2 cell cycle checkpoint enhances survival of epithelial cells exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2003 Feb; 284(2):L368-75.
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Rancourt RC, Hayes DD, Chess PR, Keng PC, O'Reilly MA. Growth arrest in G1 protects against oxygen-induced DNA damage and cell death. J Cell Physiol. 2002 Oct; 193(1):26-36.
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Baev D, Li XS, Dong J, Keng P, Edgerton M. Human salivary histatin 5 causes disordered volume regulation and cell cycle arrest in Candida albicans. Infect Immun. 2002 Sep; 70(9):4777-84.
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Matsui Y, Tsuchida Y, Keng PC. Effects of p53 mutations on cellular sensitivity to ionizing radiation. Am J Clin Oncol. 2001 Oct; 24(5):486-90.
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Cao Q, Abeysinghe H, Chow O, Xu J, Kaung H, Fong C, Keng P, Insel RA, Lee WM, Barrett JC, Wang N. Suppression of tumorigenicity in human ovarian carcinoma cell line SKOV-3 by microcell-mediated transfer of chromosome 11. Cancer Genet Cytogenet. 2001 Sep; 129(2):131-7.
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O'Reilly MA, Staversky RJ, Watkins RH, Reed CK, de Mesy Jensen KL, Finkelstein JN, Keng PC. The cyclin-dependent kinase inhibitor p21 protects the lung from oxidative stress. Am J Respir Cell Mol Biol. 2001 Jun; 24(6):703-10.
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Rancourt RC, Keng PC, Helt CE, O'Reilly MA. The role of p21(CIP1/WAF1) in growth of epithelial cells exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2001 Apr; 280(4):L617-26.
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Chen YG, Mantalaris A, Bourne P, Keng P, Wu JH. Expression of mPer1 and mPer2, two mammalian clock genes, in murine bone marrow. Biochem Biophys Res Commun. 2000 Sep 24; 276(2):724-8.
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O'Reilly MA, Staversky RJ, Watkins RH, Maniscalco WM, Keng PC. p53-independent induction of GADD45 and GADD153 in mouse lungs exposed to hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2000 Mar; 278(3):L552-9.
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Wheeler KT, Wang LM, Wallen CA, Childers SR, Cline JM, Keng PC, Mach RH. Sigma-2 receptors as a biomarker of proliferation in solid tumours. Br J Cancer. 2000 Mar; 82(6):1223-32.
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Lee J, Moran JP, Fenton BM, Koch CJ, Frelinger JG, Keng PC, Lord EM. Alteration of tumour response to radiation by interleukin-2 gene transfer. Br J Cancer. 2000 Feb; 82(4):937-44.
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Rancourt RC, Staversky RJ, Keng PC, O'Reilly MA. Hyperoxia inhibits proliferation of Mv1Lu epithelial cells independent of TGF-beta signaling. Am J Physiol. 1999 Dec; 277(6 Pt 1):L1172-8.
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Al-Nabulsi I, Mach RH, Wang LM, Wallen CA, Keng PC, Sten K, Childers SR, Wheeler KT. Effect of ploidy, recruitment, environmental factors, and tamoxifen treatment on the expression of sigma-2 receptors in proliferating and quiescent tumour cells. Br J Cancer. 1999 Nov; 81(6):925-33.
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Georgakoudi I, Keng PC, Foster TH. Hypoxia significantly reduces aminolaevulinic acid-induced protoporphyrin IX synthesis in EMT6 cells. Br J Cancer. 1999 Mar; 79(9-10):1372-7.
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de Toledo SM, Azzam EI, Keng P, Laffrenier S, Little JB. Regulation by ionizing radiation of CDC2, cyclin A, cyclin B, thymidine kinase, topoisomerase IIalpha, and RAD51 expression in normal human diploid fibroblasts is dependent on p53/p21Waf1. Cell Growth Differ. 1998 Nov; 9(11):887-96.
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Tsai MA, Waugh RE, Keng PC. Passive mechanical behavior of human neutrophils: effects of colchicine and paclitaxel. Biophys J. 1998 Jun; 74(6):3282-91.
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Nagasawa H, Keng P, Maki C, Yu Y, Little JB. Absence of a radiation-induced first-cycle G1-S arrest in p53+ human tumor cells synchronized by mitotic selection. Cancer Res. 1998 May 1; 58(9):2036-41.
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Mantalaris A, Keng P, Bourne P, Chang AY, Wu JH. Engineering a human bone marrow model: a case study on ex vivo erythropoiesis. Biotechnol Prog. 1998 Jan-Feb; 14(1):126-33.
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Keng PC, Siemann DW. Measurement of proliferation activities in human tumor models: a comparison of flow cytometric methods. Radiat Oncol Investig. 1998; 6(3):120-7.
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Wenz F, Yu Y, Nagasawa H, Imrich AC, Keng P, Little JB. Lack of uncoupling of S phase and mitosis after irradiation in p53- human lymphoblast cell lines. Radiat Res. 1997 Aug; 148(2):129-34.
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Powlin SS, Keng PC, Miller RK. Toxicity of cadmium in human trophoblast cells (JAr choriocarcinoma): role of calmodulin and the calmodulin inhibitor, zaldaride maleate. Toxicol Appl Pharmacol. 1997 Jun; 144(2):225-34.
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Masunaga S, Keng PC. Effect of caffeine on gamma-ray induced G2 arrest in well-synchronized Chinese hamster ovary cells in vitro. Radiat Med. 1996 Nov-Dec; 14(6):309-13.
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Rowley PT, Keng PC, Kosciolek BA. The effect of bcr-abl antisense oligonucleotide on DNA synthesis and apoptosis in K562 chronic myeloid leukemia cells. Leuk Res. 1996 Jun; 20(6):473-80.
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Tsai MA, Waugh RE, Keng PC. Cell cycle-dependence of HL-60 cell deformability. Biophys J. 1996 Apr; 70(4):2023-9.
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Tsai MA, Waugh RE, Keng PC. Changes in HL-60 cell deformability during differentiation induced by DMSO. Biorheology. 1996 Jan-Feb; 33(1):1-15.
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Little JB, Nagasawa H, Keng PC, Yu Y, Li CY. Absence of radiation-induced G1 arrest in two closely related human lymphoblast cell lines that differ in p53 status. J Biol Chem. 1995 May 12; 270(19):11033-6.
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Keng PC, Phipps R, Penney DP. In vitro radiation sensitivity of mouse lung fibroblasts isolated by flow cytometry. Int J Radiat Oncol Biol Phys. 1995 Feb 1; 31(3):519-23.
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Nagasawa H, Keng P, Harley R, Dahlberg W, Little JB. Relationship between gamma-ray-induced G2/M delay and cellular radiosensitivity. Int J Radiat Biol. 1994 Oct; 66(4):373-9.
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Liesveld JL, Keng PC, Rowe JM, DiPersio JF, Abboud CN. Effects of GM-CSF on Ki67 expression and cell cycle traverse in acute myelogenous leukemia specimens and cell lines. Leuk Res. 1994 Aug; 18(8):609-16.
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Grota LJ, Reiter RJ, Keng P, Michaelson S. Electric field exposure alters serum melatonin but not pineal melatonin synthesis in male rats. Bioelectromagnetics. 1994; 15(5):427-37.
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McDonald S, Chang AY, Rubin P, Wallenberg J, Kim IS, Sobel S, Smith J, Keng P, Muhs A. Combined Betaseron R (recombinant human interferon beta) and radiation for inoperable non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 1993 Oct 20; 27(3):613-9.
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Chen DS, Law C, Keng P. Reduction of radiation cytotoxicity by human apurinic endonuclease in a radiation-sensitive Escherichia coli mutant. Radiat Res. 1993 Sep; 135(3):405-10.
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Zhu W, Kriajevskaia M, Keng PC, Chou WG. A "trans-acting" factor for activation of transcription is defective in the xrs-5 mutant of the Chinese hamster ovary cell line. Mutat Res. 1993 Aug; 294(2):101-8.
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Whartenby KA, Insel RA, Freeman SM, Keng P, Abraham GN. Oncogene elements within an endogenous retrovirus. Acta Virol. 1993 Apr-Jun; 37(2-3):113-22.
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Felch ME, Willis RA, Penney DP, Keng PC, Phipps RP. Expression of alpha 6 beta 1 integrin, the laminin receptor, on subsets of normal murine lung fibroblasts and its upregulation by the inflammatory cytokines IFN-gamma and TNF-alpha. Reg Immunol. 1992 Nov-Dec; 4(6):363-70.
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Zhu W, Keng PC, Chou WG. Differential gene expression in wild-type and X-ray-sensitive mutants of Chinese hamster ovary cell lines. Mutat Res. 1992 Sep; 274(3):237-45.
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Derdak S, Penney DP, Keng P, Felch ME, Brown D, Phipps RP. Differential collagen and fibronectin production by Thy 1+ and Thy 1- lung fibroblast subpopulations. Am J Physiol. 1992 Aug; 263(2 Pt 1):L283-90.
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Chapuis JC, Keng PC, Siemann DW. Activity of etoposide (VP-16) and teniposide (VM-26) in exponential and plateau phase human tumor cell cultures. Anticancer Drugs. 1992 Jun; 3(3):245-52.
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Nasir A, Reynolds SD, Keng PC, Angerer LM, Angerer RC. Centrifugal elutriation of large fragile cells: isolation of RNA from fixed embryonic blastomeres. Anal Biochem. 1992 May 15; 203(1):22-6.
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Penney DP, Keng PC, Derdak S, Phipps RP. Morphologic and functional characteristics of subpopulations of murine lung fibroblasts grown in vitro. Anat Rec. 1992 Mar; 232(3):432-43.
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Constine LS, Harwell S, Keng P, Lee F, Rubin P, Siemann D. Interleukin 1 alpha stimulates hemopoiesis but not tumor cell proliferation and protects mice from lethal total body irradiation. Int J Radiat Oncol Biol Phys. 1991 Mar; 20(3):447-56.
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Brennan JK, Lee KS, Frazel MA, Keng PC, Young DA. Interactions of dimethyl sulfoxide and granulocyte-macrophage colony-stimulating factor on the cell cycle kinetics and phosphoproteins of G1-enriched HL-60 cells: evidence of early effects on lamin B phosphorylation. J Cell Physiol. 1991 Mar; 146(3):425-34.
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Chapuis JC, Keng PC, Siemann DW. Activity of etoposide (VP-16) in human tumor cells under different growth conditions. Int J Radiat Oncol Biol Phys. 1991 Feb; 20(2):373-5.
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Knuechel R, Keng P, Hofstaedter F, Langmuir V, Sutherland RM, Penney DP. Differentiation patterns in two- and three-dimensional culture systems of human squamous carcinoma cell lines. Am J Pathol. 1990 Sep; 137(3):725-36.
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Phipps RP, Baecher C, Frelinger JG, Penney DP, Keng P, Brown D. Differential expression of interleukin 1 alpha by Thy-1+ and Thy-1- lung fibroblast subpopulations: enhancement of interleukin 1 alpha production by tumor necrosis factor-alpha. Eur J Immunol. 1990 Aug; 20(8):1723-7.
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Keng PC, Allalunis-Turner J, Siemann DW. Evaluation of cell subpopulations isolated from human tumor xenografts by centrifugal elutriation. Int J Radiat Oncol Biol Phys. 1990 May; 18(5):1061-7.
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Loeffler DA, Keng PC, Baggs RB, Lord EM. Lymphocytic infiltration and cytotoxicity under hypoxic conditions in the EMT6 mouse mammary tumor. Int J Cancer. 1990 Mar 15; 45(3):462-7.
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Wilson RE, Keng PC, Sutherland RM. Erratum: Drug resistance in Chinese hamster ovary cells during recovery from severe hypoxia. J Natl Cancer Inst. 1990 Feb 7; 82(3):239.
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Phipps RP, Penney DP, Keng P, Silvera M, Harkins S, Derdak S. Immune functions of subpopulations of lung fibroblasts. Immunol Res. 1990; 9(4):275-86.
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Wilson RE, Keng PC, Sutherland RM. Changes in growth characteristics and macromolecular synthesis on recovery from severe hypoxia. Br J Cancer. 1990 Jan; 61(1):14-21.
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Knüchel R, Hofstaedter F, Sutherland RM, Keng PC. [Proliferation-associated antigens PCNA and Ki-67 in two- and three-dimensional experimental systems of human squamous epithelial carcinomas]. Verh Dtsch Ges Pathol. 1990; 74:275-8.
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Domurat FM, Keng P, Mock DJ, Roberts NJ. Early identification and retrieval or deletion of human lymphocyte subpopulations responding to influenza virus or respiratory syncytial virus challenge. Cell Biophys. 1989 Dec; 15(3):173-88.
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Wilson RE, Keng PC, Sutherland RM. Drug resistance in Chinese hamster ovary cells during recovery from severe hypoxia. J Natl Cancer Inst. 1989 Aug 16; 81(16):1235-40.
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Phipps RP, Penney DP, Keng P, Quill H, Paxhia A, Derdak S, Felch ME. Characterization of two major populations of lung fibroblasts: distinguishing morphology and discordant display of Thy 1 and class II MHC. Am J Respir Cell Mol Biol. 1989 Jul; 1(1):65-74.
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Liu YC, Marraccino RL, Keng PC, Bambara RA, Lord EM, Chou WG, Zain SB. Requirement for proliferating cell nuclear antigen expression during stages of the Chinese hamster ovary cell cycle. Biochemistry. 1989 Apr 4; 28(7):2967-74.
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Wilson KM, Keng PC. Radiation-induced DNA damage and repair in quiescent and proliferating human tumor cells in vitro. Int J Radiat Biol. 1989 Mar; 55(3):385-95.
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White TE, Saltzman RA, Di Sant'Agnese PA, Keng PC, Sutherland RM, Miller RK. Human choriocarcinoma (JAr) cells grown as multicellular spheroids. Placenta. 1988 Nov-Dec; 9(6):583-98.
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Gringeri A, Keng PC, Borch RF. Diethyldithiocarbamate inhibition of murine bone marrow toxicity caused by cis-diamminedichloroplatinum(II) or diammine-(1,1-cyclobutanedicarboxylato)platinum(II). Cancer Res. 1988 Oct 15; 48(20):5708-12.
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Siemann DW, Keng PC. Characterization of radiation resistant hypoxic cell subpopulations in KHT sarcomas. (II). Cell sorting. Br J Cancer. 1988 Sep; 58(3):296-300.
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Lee FY, Siemann DW, Allalunis-Turner MJ, Keng PC. Glutathione contents in human and rodent tumor cells in various phases of the cell cycle. Cancer Res. 1988 Jul 1; 48(13):3661-5.
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Wingrove TG, Watt R, Keng P, Macara IG. Stabilization of myc proto-oncogene proteins during Friend murine erythroleukemia cell differentiation. J Biol Chem. 1988 Jun 25; 263(18):8918-24.
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West CM, Keng PC, Sutherland RM. Growth phase related variation in the radiation sensitivity of human colon adenocarcinoma cells. Int J Radiat Oncol Biol Phys. 1988 Jun; 14(6):1213-9.
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Wu DZ, Keng P. Effects of bleomycins on synchronized cells by centrifugal elutriation. Zhongguo Yao Li Xue Bao. 1988 Mar; 9(2):170-4.
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Siemann DW, Keng PC. Responses of tumor cell subpopulations to single modality and combined modality therapies. NCI Monogr. 1988; (6):101-5.
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Palis J, King B, Keng P. Separation of spontaneously differentiating and cell cycle-specific populations of HL-60 cells. Leuk Res. 1988; 12(4):339-44.
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Marraccino RL, Wahl AF, Keng PC, Lord EM, Bambara RA. Cell cycle dependent activities of DNA polymerases alpha and delta in Chinese hamster ovary cells. Biochemistry. 1987 Dec 1; 26(24):7864-70.
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Loeffler DA, Keng PC, Wilson KM, Lord EM. Comparison of fluorescence intensity of Hoechst 33342-stained EMT6 tumour cells and tumour-infiltrating host cells. Br J Cancer. 1987 Nov; 56(5):571-6.
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Ng CE, Keng PC, Sutherland RM. Characterization of radiation sensitivity of human squamous carcinoma A431 cells. Br J Cancer. 1987 Sep; 56(3):301-7.
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Chang AY, Keng PC. Potentiation of radiation cytotoxicity by recombinant interferons, a phenomenon associated with increased blockage at the G2-M phase of the cell cycle. Cancer Res. 1987 Aug 15; 47(16):4338-41.
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Brennan JK, Lee KS, Abboud CN, Erickson-Miller CL, Keng PC. Interactions of dimethyl sulfoxide and granulocyte-macrophage colony-stimulating factors on the growth and maturation of HL-60 cells. J Cell Physiol. 1987 Aug; 132(2):246-54.
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West CM, Keng PC, Siemann DW, Sutherland RM. A human colon adenocarcinoma xenograft--radiation response, cellular composition, and tumor disaggregation. J Natl Cancer Inst. 1987 Feb; 78(2):371-6.
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Mock DJ, Domurat F, Roberts NJ, Walsh EE, Licht MR, Keng P. Macrophages are required for influenza virus infection of human lymphocytes. J Clin Invest. 1987 Feb; 79(2):620-4.
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Lett JT, Keng PC, Bergtold DS, Howard J. Effects of heavy ions on rabbit tissues: induction of DNA strand breaks in retinal photoreceptor cells by high doses of radiation. Radiat Environ Biophys. 1987; 26(1):23-36.
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Siemann DW, Keng PC. Characterization of radiation resistant hypoxic cell subpopulations in KHT sarcomas. (I). Centrifugal elutriation. Br J Cancer. 1987 Jan; 55(1):33-6.
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Ng CE, Keng PC, Sutherland RM. Density distributions of human squamous carcinoma cells: influence of growth conditions, proliferative status and DNA content. Int J Cancer. 1986 Sep 15; 38(3):413-8.
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Keng PC. Use of flow cytometry in the measurement of cell mitotic cycle. Int J Cell Cloning. 1986 Sep; 4(5):295-311.
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Siemann DW, Keng PC. Cell cycle specific toxicity of the Hoechst 33342 stain in untreated or irradiated murine tumor cells. Cancer Res. 1986 Jul; 46(7):3556-9.
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Scott DW, Livnat D, Pennell CA, Keng P. Lymphoma models for B cell activation and tolerance. III. Cell cycle dependence for negative signalling of WEHI-231 B lymphoma cells by anti-mu. J Exp Med. 1986 Jul 1; 164(1):156-64.
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Luk CK, Keng PC, Sutherland RM. Radiation response of proliferating and quiescent subpopulations isolated from multicellular spheroids. Br J Cancer. 1986 Jul; 54(1):25-32.
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Bodenner DL, Dedon PC, Keng PC, Katz JC, Borch RF. Selective protection against cis-diamminedichloroplatinum(II)-induced toxicity in kidney, gut, and bone marrow by diethyldithiocarbamate. Cancer Res. 1986 Jun; 46(6):2751-5.
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Bodenner DL, Dedon PC, Keng PC, Borch RF. Effect of diethyldithiocarbamate on cis-diamminedichloroplatinum(II)-induced cytotoxicity, DNA cross-linking, and gamma-glutamyl transpeptidase inhibition. Cancer Res. 1986 Jun; 46(6):2745-50.
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Brosing JW, Keng PC, Mulcahy RT. Survival characteristics of normal differentiated rat thyroid cells maintained in vitro. Radiat Res. 1986 Feb; 105(2):138-46.
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Lett JT, Bertold DS, Keng PC. Effects of LET infinity on the fate of DNA damage induced in rabbit sensory cells in situ: fundamental aspects. Basic Life Sci. 1986; 38:139-50.
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Wu DZ, Zhang YQ, Keng P, Sutherland RM, Lasagna L. The interaction between bleomycin and radiation on cell survival and DNA damage in mammalian cell cultures. Int J Radiat Oncol Biol Phys. 1985 Dec; 11(12):2125-31.
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Scott DW, Tuttle J, Livnat D, Haynes W, Cogswell JP, Keng P. Lymphoma models for B-cell activation and tolerance. II. Growth inhibition by anti-mu of WEHI-231 and the selection and properties of resistant mutants. Cell Immunol. 1985 Jun; 93(1):124-31.
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Luk CK, Keng PC, Sutherland RM. Regrowth and radiation sensitivity of quiescent cells isolated from EMT6/Ro-fed plateau monolayers. Cancer Res. 1985 Mar; 45(3):1020-5.
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Siemann DW, Maddison K, Wolf K, Hill SA, Keng PC. In vivo interaction between radiation and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in the absence or presence of misonidazole in mice. Cancer Res. 1985 Jan; 45(1):198-202.
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Keng PC, Siemann DW, Wheeler KT. Comparison of tumour age response to radiation for cells derived from tissue culture or solid tumours. Br J Cancer. 1984 Oct; 50(4):519-26.
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Keng PC, Rubin P, Constine LS, Frantz C, Nakissa N, Gregory P. Characterization of the biophysical properties of human tumor and bone marrow cells as a preliminary step to the use of centrifugal elutriation in autologous bone marrow transplantation. Int J Radiat Oncol Biol Phys. 1984 Oct; 10(10):1913-22.
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Siemann DW, Keng PC. In situ radiation response and oxygen enhancement ratio of KHT sarcoma cells in various phases of the cell cycle. Br J Radiol. 1984 Sep; 57(682):823-7.
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Hill SA, Keng PC, Siemann DW. Survival in subpopulations of cells derived from solid KHT sarcomas by centrifugal elutriation following treatment with CCNU and MISO. Int J Radiat Oncol Biol Phys. 1984 Sep; 10(9):1615-8.
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Hill SA, Bauer KD, Keng PC, Siemann DW. The effect in the KHT sarcoma of CCNU and MISO on cell cycle progression evaluated by flow-cytometry. Int J Radiat Oncol Biol Phys. 1984 Sep; 10(9):1619-22.
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Lord EM, Keng PC. Methods for using centrifugal elutriation to separate malignant and lymphoid cell populations. J Immunol Methods. 1984 Mar 30; 68(1-2):147-55.
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Lett JT, Bergtold DS, Cox AB, Keng PC, Okayasu R. Further evidence that the survival of irradiated mammalian cells is controlled by temporal processes. Br J Cancer Suppl. 1984; 6:163-8.
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Keng PC, Bergtold DS, Lett JT. Effects of heavy ions on rabbit tissues: analysis of low levels of DNA damage in retinal photoreceptor cells. Int J Radiat Biol Relat Stud Phys Chem Med. 1983 Mar; 43(3):219-29.
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Chang AY, Keng PC. Inhibition of cell growth in synchronous human hypernephroma cells by recombinant interferon alpha-D and irradiation. J Interferon Res. 1983; 3(4):379-85.
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Cox AB, Keng PC, Lee AC, Lett JT. Effects of heavy ions on rabbit tissues: damage to the forebrain. Int J Radiat Biol Relat Stud Phys Chem Med. 1982 Oct; 42(4):355-67.
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Sutherland RM, Keng P, Conroy PJ, McDermott D, Bareham BJ, Passalacqua W. In vitro hypoxic cytotoxicity of nitroimidazoles: uptake and cell cycle phase specificity. Int J Radiat Oncol Biol Phys. 1982 Mar-Apr; 8(3-4):745-8.
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Keng PC, Lee AC, Cox AB, Bergtold DS, Lett JT. Effects of heavy ions on rabbit tissues: cataractogenesis. Int J Radiat Biol Relat Stud Phys Chem Med. 1982 Feb; 41(2):127-37.
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Bauer KD, Keng PC, Sutherland RM. Isolation of quiescent cells from multicellular tumor spheroids using centrifugal elutriation. Cancer Res. 1982 Jan; 42(1):72-8.
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Cox AB, Keng PC, Glass NL, Lett JT. Effects of heavy ions on rabbit tissues: alopecia. Int J Radiat Biol Relat Stud Phys Chem Med. 1981 Dec; 40(6):645-57.
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Rubin P, Wheeler KT, Keng PC, Gregory PK, Croizat H. The separation of a mixture of bone marrow stem cells from tumor cells: an essential step for autologous bone marrow transplantation. Int J Radiat Oncol Biol Phys. 1981 Oct; 7(10):1405-11.
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Keng PC, Wheeler KT, Siemann DW, Lord EM. Direct synchronization of cells from solid tumors by centrifugal elutriation. Exp Cell Res. 1981 Jul; 134(1):15-22.
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Siemann DW, Lord EM, Keng PC, Wheeler KT. Cell subpopulations dispersed from solid tumours and separated by centrifugal elutriation. Br J Cancer. 1981 Jul; 44(1):100-8.
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Keng PC, Lett JT. Effects of heavy ions on rabbit tissues: loss of electroretinogram and DNA repair in retinal photoreceptor cells. Int J Radiat Biol Relat Stud Phys Chem Med. 1981 Jun; 39(6):655-64.
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Keng PC, Li CK, Wheeler KT. Characterization of the separation properties of the Beckman elutriator system. Cell Biophys. 1981 Mar; 3(1):41-56.
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Keng PC, Li CK, Wheeler KT. Synchronization of 9L rat brain tumor cells by centrifugal elutriation. Cell Biophys. 1980 Sep; 2(3):191-206.
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Keng PC, Wheeler KT. Radiation response of synchronized 9L rat brain tumor cells separated by centrifugal elutriation. Radiat Res. 1980 Sep; 83(3):633-43.
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Lett JT, Cox AB, Keng PC, Lee AC, Su CM, Bergtold DS. Late degeneration in rabbit tissues after irradiation by heavy ions. Life Sci Space Res. 1980; 18:131-42.
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