URMC Research Network

Find People
Keyword
Last Name
 
More Search Options

David Topham

Concepts (367)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of pubs Most recent pub Pubs by all authors Concept score Why?
Orthomyxoviridae Infections
21
1995
94
6.880
Why?
CD8-Positive T-Lymphocytes
20
1996
221
5.320
Why?
CD4-Positive T-Lymphocytes
23
1991
296
4.580
Why?
Immunologic Memory
18
1996
124
3.050
Why?
Influenza A Virus, H1N1 Subtype
7
2006
85
2.720
Why?
Influenza A virus
14
1995
225
2.550
Why?
Integrin alpha1beta1
4
2004
6
2.440
Why?
Hemagglutinin Glycoproteins, Influenza Virus
5
2008
42
2.420
Why?
Influenza, Human
8
2006
353
2.140
Why?
Influenza A Virus, H3N2 Subtype
6
2007
60
2.100
Why?
Influenza Vaccines
8
2008
265
2.040
Why?
Lung
12
1996
1142
2.000
Why?
Mice, Inbred C57BL
34
1995
1683
1.960
Why?
Mice
63
1987
6103
1.880
Why?
B-Lymphocytes
11
1996
453
1.630
Why?
Antibodies, Viral
14
1989
468
1.560
Why?
Cell Movement
7
1995
376
1.470
Why?
Antigens, Viral
4
2001
148
1.410
Why?
Lymphocyte Activation
12
1991
402
1.320
Why?
Animals
65
1987
16270
1.320
Why?
Spleen
9
1994
339
1.200
Why?
Orthomyxoviridae
4
1997
58
1.080
Why?
T-Lymphocyte Subsets
4
2006
109
1.040
Why?
T-Lymphocytes
12
1987
545
1.040
Why?
Influenza A Virus, H5N1 Subtype
2
2010
27
0.980
Why?
Pandemics
2
2010
10
0.970
Why?
Collagen
2
2004
299
0.940
Why?
Killer Cells, Natural
3
2006
119
0.930
Why?
Lymphocyte Subsets
2
2009
29
0.900
Why?
Immunity, Cellular
3
1998
133
0.900
Why?
Influenza B virus
1
2012
43
0.830
Why?
Genetic Drift
1
2011
3
0.830
Why?
Cross Protection
1
2011
3
0.830
Why?
Cross Reactions
5
2009
107
0.810
Why?
Vaccinia
2
2006
13
0.740
Why?
Interleukins
1
2010
61
0.730
Why?
Antigens, CD95
2
1997
22
0.720
Why?
Interferon-gamma
7
1999
345
0.710
Why?
Blood
1
2009
95
0.700
Why?
Membrane Glycoproteins
3
1997
365
0.630
Why?
Herpesviridae Infections
3
2000
68
0.630
Why?
Receptors, Tumor Necrosis Factor, Type II
1
2007
8
0.630
Why?
Liver
4
1998
876
0.620
Why?
Female
27
1987
19826
0.620
Why?
Integrin alpha2beta1
1
2007
9
0.600
Why?
Histocompatibility Antigens Class I
4
1996
94
0.580
Why?
Histocompatibility Antigens Class II
5
1987
190
0.580
Why?
Smallpox
1
2006
14
0.570
Why?
Smallpox Vaccine
1
2006
10
0.570
Why?
Respiratory Mucosa
1
2007
83
0.570
Why?
Mice, Knockout
13
1996
918
0.550
Why?
Disease Models, Animal
5
1996
973
0.540
Why?
Apoptosis
3
2003
855
0.540
Why?
Immunoglobulin G
5
2003
482
0.540
Why?
Mice, Inbred BALB C
10
1987
621
0.540
Why?
Pneumonia, Viral
3
1997
28
0.530
Why?
Immunoglobulin M
3
1996
140
0.510
Why?
Gammaherpesvirinae
2
2000
6
0.500
Why?
Mice, Transgenic
9
2000
769
0.500
Why?
Antibody Formation
3
2006
176
0.480
Why?
Lymph Nodes
6
1996
207
0.470
Why?
Adoptive Transfer
4
2001
30
0.440
Why?
Interleukin-2
7
1996
194
0.440
Why?
Peptide Fragments
4
1994
301
0.430
Why?
Flow Cytometry
8
1994
597
0.430
Why?
Hemagglutination Inhibition Tests
2
2011
74
0.410
Why?
Antibodies, Neutralizing
2
2011
35
0.400
Why?
Immunophenotyping
4
1995
124
0.390
Why?
Encephalomyelitis, Autoimmune, Experimental
4
1987
12
0.380
Why?
Leukocytes, Mononuclear
2
2008
110
0.340
Why?
Respirovirus
1
1998
11
0.340
Why?
Cell Proliferation
3
2006
521
0.340
Why?
Respirovirus Infections
1
1998
63
0.330
Why?
Humans
22
1994
36400
0.320
Why?
Cell Separation
2
2007
227
0.310
Why?
Bone Marrow Cells
4
1998
223
0.310
Why?
Vaccinia virus
2
2006
53
0.310
Why?
Receptors, Antigen, T-Cell
4
1996
68
0.300
Why?
Kupffer Cells
2
2006
20
0.290
Why?
Agammaglobulinemia
1
1996
14
0.290
Why?
Enzyme-Linked Immunosorbent Assay
5
1996
466
0.290
Why?
Cell Communication
2
2003
141
0.280
Why?
Adult
9
2006
11345
0.270
Why?
Lymphocytes
4
1994
274
0.270
Why?
Milk Proteins
3
1999
15
0.260
Why?
Cell Survival
5
2003
561
0.260
Why?
Cell Line
6
1994
1594
0.260
Why?
Organ Specificity
2
2003
157
0.260
Why?
Male
9
1996
19713
0.250
Why?
Cell Differentiation
6
1998
1098
0.250
Why?
Time Factors
4
1995
3201
0.250
Why?
Kinetics
3
2000
1464
0.240
Why?
Vaccines, Synthetic
1
1994
89
0.240
Why?
Ovalbumin
2
2001
54
0.240
Why?
Middle Aged
6
2006
9877
0.230
Why?
Viral Load
2
2010
131
0.230
Why?
Cytokines
5
1998
572
0.230
Why?
Amino Acid Sequence
5
1994
1231
0.230
Why?
Molecular Sequence Data
6
1994
2028
0.230
Why?
Epitopes, T-Lymphocyte
2
2009
31
0.230
Why?
DNA-Binding Proteins
6
1998
687
0.230
Why?
Virulence
2
2009
150
0.220
Why?
Malaria
2
2009
22
0.220
Why?
Repressor Proteins
3
1999
181
0.220
Why?
Hematopoietic Stem Cells
3
1998
190
0.220
Why?
Hemagglutination Tests
1
2012
22
0.220
Why?
Integrins
2
2009
48
0.210
Why?
Chemokines
2
2004
112
0.210
Why?
Ki-67 Antigen
1
2012
28
0.210
Why?
Encephalomyocarditis virus
2
1989
8
0.210
Why?
Antigens, Differentiation, T-Lymphocyte
2
1989
35
0.210
Why?
Recombinant Proteins
2
2009
768
0.210
Why?
Models, Theoretical
2
2009
189
0.200
Why?
Cell Cycle
4
1998
248
0.200
Why?
Antigen Presentation
1
2012
75
0.200
Why?
Virus Diseases
2
1997
81
0.200
Why?
Encephalomyelitis
1
1991
4
0.200
Why?
Poliomyelitis
1
1991
4
0.200
Why?
Lectins, C-Type
1
2011
23
0.200
Why?
Young Adult
3
2008
1074
0.200
Why?
Neutralization Tests
1
2011
129
0.200
Why?
Liver Transplantation
3
2007
238
0.200
Why?
Cyclooxygenase 2
2
2009
226
0.200
Why?
Models, Immunological
1
2011
59
0.200
Why?
Vaccination
3
1996
241
0.200
Why?
Phenotype
3
1998
762
0.190
Why?
Proteasome Endopeptidase Complex
1
2011
71
0.190
Why?
Epithelial Cells
2
2010
328
0.190
Why?
Microarray Analysis
1
2010
36
0.190
Why?
Antigens, CD27
1
2010
8
0.190
Why?
Receptors, Interleukin
1
2010
9
0.190
Why?
Cell Count
1
2011
286
0.190
Why?
T-Lymphocytes, Regulatory
1
1991
50
0.190
Why?
Antibody-Producing Cells
2
2000
34
0.190
Why?
Lymphoid Tissue
2
1997
45
0.190
Why?
Biosensing Techniques
1
2010
32
0.180
Why?
Cytopathogenic Effect, Viral
1
2010
26
0.180
Why?
Immunity, Innate
1
2011
102
0.180
Why?
Half-Life
1
2010
103
0.180
Why?
Pore Forming Cytotoxic Proteins
2
1997
9
0.180
Why?
Perforin
2
1997
9
0.180
Why?
Hong Kong
1
2009
23
0.180
Why?
T-Lymphocytes, Helper-Inducer
2
2006
92
0.180
Why?
Immunity, Humoral
1
2009
19
0.180
Why?
MAP Kinase Kinase Kinases
1
2010
45
0.180
Why?
Cyclooxygenase 2 Inhibitors
1
2009
64
0.170
Why?
Blood Platelets
1
2012
280
0.170
Why?
T-Lymphocytes, Cytotoxic
1
2010
122
0.170
Why?
Antigens, CD
1
2011
245
0.170
Why?
Ibuprofen
1
2009
10
0.170
Why?
4-1BB Ligand
1
2009
1
0.170
Why?
Cells, Cultured
8
1995
2563
0.170
Why?
Toll-Like Receptor 9
1
2009
11
0.170
Why?
Plasmodium falciparum
1
2009
19
0.170
Why?
Body Weight
1
2010
338
0.170
Why?
Inflammation
2
2007
550
0.170
Why?
Up-Regulation
1
2011
372
0.170
Why?
Peptides
1
2011
288
0.170
Why?
Cytotoxicity, Immunologic
2
1997
110
0.170
Why?
Protein C
1
2009
47
0.170
Why?
Cyclooxygenase Inhibitors
1
2009
66
0.170
Why?
Oligodeoxyribonucleotides
1
2009
139
0.160
Why?
B-Lymphocyte Subsets
1
2009
65
0.160
Why?
Cell Adhesion
3
1995
272
0.160
Why?
P-Glycoprotein
2
1998
66
0.160
Why?
Integrin alpha1
1
2007
1
0.160
Why?
Anti-Inflammatory Agents, Non-Steroidal
1
2009
94
0.160
Why?
Survival Analysis
1
2010
598
0.160
Why?
Influenza A Virus, H2N2 Subtype
1
2007
3
0.150
Why?
Antigens, CD28
1
2007
34
0.150
Why?
Cell Aggregation
1
2007
27
0.150
Why?
HLA-DR1 Antigen
1
2007
4
0.150
Why?
Trans-Activators
3
1999
364
0.150
Why?
Hemagglutinins, Viral
1
2007
21
0.150
Why?
Transcription, Genetic
1
2011
815
0.140
Why?
Neutrophils
1
2009
312
0.140
Why?
Gene Expression Regulation, Developmental
2
1999
332
0.140
Why?
Hepatitis
1
2006
15
0.140
Why?
Antibodies, Monoclonal
4
1987
732
0.140
Why?
Vaccines, Subunit
1
2006
11
0.140
Why?
Viral Plaque Assay
1
2005
28
0.140
Why?
Monocytes
1
2007
314
0.130
Why?
Macrophages
1
2007
347
0.130
Why?
Dogs
1
2005
488
0.130
Why?
Bacterial Infections
1
2006
125
0.120
Why?
Hypersensitivity
1
2004
44
0.120
Why?
Transcription Factors
2
1999
689
0.120
Why?
Immunocompetence
1
2004
30
0.120
Why?
In Situ Nick-End Labeling
1
2004
95
0.120
Why?
Immunoglobulin A
1
2003
90
0.120
Why?
Ligands
3
2006
295
0.120
Why?
Virus Replication
3
1991
283
0.120
Why?
Bone Marrow Transplantation
2
1999
186
0.110
Why?
Adolescent
3
2006
4752
0.110
Why?
Lung Diseases
1
2004
224
0.110
Why?
Retroviridae
2
1998
67
0.110
Why?
Erythropoiesis
2
1998
49
0.110
Why?
Genes, T-Cell Receptor
1
2001
1
0.110
Why?
Egg Proteins
1
2001
5
0.110
Why?
Rhadinovirus
1
2001
3
0.110
Why?
Mice, Inbred Strains
4
1987
242
0.100
Why?
DNA, Recombinant
1
2001
40
0.100
Why?
Kidney
1
2005
582
0.100
Why?
Lymphocyte Cooperation
2
1998
25
0.100
Why?
Virus Latency
1
2001
13
0.100
Why?
Chimera
1
2001
34
0.100
Why?
Antigens, CD44
2
1995
17
0.100
Why?
Transfection
3
1998
876
0.100
Why?
Carrier Proteins
3
1995
434
0.090
Why?
Gene Targeting
1
2000
69
0.090
Why?
Lymphocyte Depletion
2
1995
58
0.090
Why?
Immunohistochemistry
1
2004
1063
0.090
Why?
DNA, Viral
1
2001
305
0.090
Why?
Protein-Tyrosine Kinases
2
1998
179
0.090
Why?
Antibody Specificity
1
2000
108
0.090
Why?
Lymphocyte Count
2
1996
53
0.090
Why?
Tissue Distribution
3
1997
236
0.090
Why?
Convalescence
1
1998
19
0.080
Why?
Myeloproliferative Disorders
1
1998
18
0.080
Why?
Parainfluenza Virus 1, Human
2
1995
37
0.080
Why?
Lymphoproliferative Disorders
1
1998
29
0.080
Why?
Receptors, Cytokine
1
1998
10
0.080
Why?
CD4 Lymphocyte Count
1
1998
148
0.080
Why?
Thymus Gland
4
1998
143
0.080
Why?
Mice, Inbred MRL lpr
1
1997
1
0.080
Why?
Radiation Chimera
1
1997
14
0.080
Why?
Hematopoietic Stem Cell Transplantation
1
1998
117
0.070
Why?
Intracellular Signaling Peptides and Proteins
1
1999
148
0.070
Why?
Immunoglobulin mu-Chains
1
1996
10
0.070
Why?
Acute Disease
1
1998
580
0.070
Why?
Germinal Center
1
1996
17
0.070
Why?
Tumor Necrosis Factor-alpha
2
1991
695
0.070
Why?
Crosses, Genetic
1
1996
58
0.070
Why?
Immunity
1
1997
64
0.070
Why?
Immunoglobulin Variable Region
1
1996
43
0.070
Why?
Proteins
1
1999
467
0.070
Why?
Signal Transduction
3
1998
1626
0.070
Why?
Bone Marrow
1
1997
290
0.070
Why?
Proto-Oncogene Proteins
1
1998
297
0.070
Why?
Suppressor of Cytokine Signaling Proteins
3
1999
15
0.070
Why?
STAT5 Transcription Factor
3
1999
11
0.070
Why?
Dendritic Cells
1
1996
121
0.060
Why?
Mice, Mutant Strains
3
1999
126
0.060
Why?
HLA-DR Antigens
1
1994
54
0.060
Why?
Hematopoiesis
3
1998
123
0.060
Why?
Central Nervous System
1
1995
117
0.060
Why?
Autoimmune Diseases
1
1994
84
0.060
Why?
Mice, Congenic
1
2012
6
0.050
Why?
Plasmodium berghei
1
2012
6
0.050
Why?
Lung Transplantation
1
2012
11
0.050
Why?
Cell Division
3
1998
766
0.050
Why?
Receptors, Lymphocyte Homing
3
1995
11
0.050
Why?
Transforming Growth Factor beta
1
1995
413
0.050
Why?
Picornaviridae Infections
1
1991
13
0.050
Why?
Fibroblasts
2
1998
545
0.050
Why?
Antigen-Presenting Cells
2
1995
104
0.050
Why?
Viremia
1
1991
27
0.050
Why?
Leukocyte Count
1
1991
159
0.050
Why?
Luminescent Measurements
1
2011
50
0.050
Why?
Encephalitis
1
1991
56
0.050
Why?
Antigens
1
2011
99
0.050
Why?
Antigens, CD8
2
1989
29
0.050
Why?
Enterovirus Infections
1
1989
23
0.040
Why?
Disease Outbreaks
1
2010
116
0.040
Why?
Models, Biological
2
1999
1023
0.040
Why?
Epitopes, B-Lymphocyte
1
2009
5
0.040
Why?
Malaria Vaccines
1
2009
3
0.040
Why?
Aluminum Hydroxide
1
2009
13
0.040
Why?
Clinical Trials, Phase I as Topic
1
2009
11
0.040
Why?
Antigens, CD137
1
2009
1
0.040
Why?
CpG Islands
1
2009
25
0.040
Why?
Cyclooxygenase 1
1
2009
71
0.040
Why?
Administration, Intranasal
1
2009
61
0.040
Why?
Immunodominant Epitopes
1
2009
23
0.040
Why?
Immunization, Secondary
1
2009
71
0.040
Why?
Pyrazoles
1
2009
59
0.040
Why?
Demyelinating Diseases
1
1989
76
0.040
Why?
Respiratory Function Tests
1
2009
122
0.040
Why?
Interleukin-4
2
1999
154
0.040
Why?
Disease Susceptibility
2
1987
80
0.040
Why?
Measles virus
1
2007
9
0.040
Why?
Tumor Escape
1
2007
2
0.040
Why?
Adjuvants, Immunologic
1
2009
120
0.040
Why?
Clone Cells
2
1996
186
0.040
Why?
Cancer Vaccines
1
2007
29
0.040
Why?
Macrophage Activation
1
2007
58
0.040
Why?
Isoantibodies
1
1987
56
0.040
Why?
Antiviral Agents
1
2009
169
0.040
Why?
Animals, Newborn
2
1999
505
0.040
Why?
HIV
1
2007
82
0.040
Why?
Computer Simulation
1
2009
298
0.040
Why?
Herpesvirus 1, Human
1
2007
66
0.040
Why?
Whole-Body Irradiation
1
2007
82
0.040
Why?
Predictive Value of Tests
1
2009
601
0.040
Why?
Viral Vaccines
1
2007
108
0.040
Why?
Proto-Oncogene Proteins c-bcl-2
1
2007
119
0.040
Why?
Sequence Homology, Amino Acid
1
2007
288
0.040
Why?
Intracellular Fluid
1
2006
42
0.040
Why?
Alanine Transaminase
1
2006
24
0.040
Why?
Listeria monocytogenes
1
2006
6
0.030
Why?
Dose-Response Relationship, Drug
2
1999
1138
0.030
Why?
Tetanus Toxoid
1
2006
40
0.030
Why?
Homeostasis
2
1996
177
0.030
Why?
Leukocytes
2
1995
180
0.030
Why?
Hepatocytes
1
2006
56
0.030
Why?
Dimerization
1
2006
169
0.030
Why?
Phosphorylation
2
1998
833
0.030
Why?
Bronchial Hyperreactivity
1
2004
25
0.030
Why?
DNA
2
1999
856
0.030
Why?
Th1 Cells
1
2004
70
0.030
Why?
Severity of Illness Index
1
2009
919
0.030
Why?
Th2 Cells
1
2004
91
0.030
Why?
Antigens, CD40
1
2003
51
0.030
Why?
Gene Expression Regulation
1
2009
875
0.030
Why?
Alleles
2
1987
202
0.030
Why?
Base Sequence
1
2006
1704
0.020
Why?
Neoplasms
1
2007
723
0.020
Why?
Janus Kinase 3
1
1999
4
0.020
Why?
Receptors, Interleukin-4
1
1999
4
0.020
Why?
Receptors, Interleukin-2
1
1999
31
0.020
Why?
Embryo, Mammalian
1
2000
173
0.020
Why?
Antigens, CD3
1
1999
37
0.020
Why?
Autoantibodies
1
2000
105
0.020
Why?
Interleukin-7
1
1999
9
0.020
Why?
RNA-Binding Proteins
1
2000
129
0.020
Why?
Harvey murine sarcoma virus
1
1998
1
0.020
Why?
Stem Cell Factor
1
1998
17
0.020
Why?
Genes, MDR
1
1998
10
0.020
Why?
Models, Genetic
1
1999
160
0.020
Why?
X Chromosome
1
1998
36
0.020
Why?
Thymus Neoplasms
1
1998
23
0.020
Why?
Mutagenesis
1
1999
142
0.020
Why?
In Situ Hybridization
1
1999
314
0.020
Why?
Interleukin-3
1
1998
43
0.020
Why?
Interferon Regulatory Factor-1
1
1998
4
0.020
Why?
Thrombopoietin
1
1998
7
0.020
Why?
Janus Kinase 2
1
1998
14
0.020
Why?
Colony-Stimulating Factors
1
1998
27
0.020
Why?
Transduction, Genetic
1
1998
119
0.020
Why?
CD40 Ligand
1
1998
89
0.020
Why?
Graft Survival
1
1998
145
0.020
Why?
Lymphoma
1
1998
163
0.020
Why?
Respiratory Tract Diseases
1
1997
44
0.020
Why?
Tyrosine
1
1998
145
0.020
Why?
Gene Transfer Techniques
1
1998
145
0.020
Why?
Conalbumin
1
1996
3
0.020
Why?
Phosphoproteins
1
1998
178
0.020
Why?
Indicator Dilution Techniques
1
1996
5
0.020
Why?
Genetic Vectors
1
1998
339
0.020
Why?
Polymerase Chain Reaction
1
1998
594
0.020
Why?
Age Factors
1
1999
1121
0.020
Why?
Interleukin-6
1
1998
340
0.020
Why?
Dose-Response Relationship, Immunologic
1
1995
60
0.020
Why?
Antigens, CD45
1
1995
38
0.020
Why?
Antigens, CD4
1
1995
38
0.020
Why?
Immunosuppressive Agents
1
1996
196
0.020
Why?
Blood-Brain Barrier
1
1995
108
0.020
Why?
Down-Regulation
1
1995
244
0.010
Why?
Receptors, Cell Surface
1
1995
215
0.010
Why?
Regression Analysis
1
1995
524
0.010
Why?
Picornaviridae
1
1991
1
0.010
Why?
Endothelium, Vascular
1
1995
445
0.010
Why?
RNA, Messenger
1
1998
1857
0.010
Why?
Paralysis
1
1989
54
0.010
Why?
Astrocytes
1
1991
290
0.010
Why?
Immunization, Passive
1
1987
64
0.010
Why?
Brain
1
1991
1221
0.010
Why?

Visualizations


Topham's Networks

Concepts
_
Co-Authors
_
Similar People
_
Same Department