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David Topham

Concepts (367)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of pubs Most recent pub Pubs by all authors Concept score Why?
Orthomyxoviridae Infections
21
1995
94
6.940
Why?
CD8-Positive T-Lymphocytes
20
1996
229
5.350
Why?
CD4-Positive T-Lymphocytes
23
1991
298
4.600
Why?
Immunologic Memory
18
1996
129
3.060
Why?
Influenza A Virus, H1N1 Subtype
7
2006
85
2.740
Why?
Influenza A virus
14
1995
218
2.590
Why?
Integrin alpha1beta1
4
2004
6
2.460
Why?
Hemagglutinin Glycoproteins, Influenza Virus
5
2008
43
2.440
Why?
Influenza, Human
8
2006
345
2.180
Why?
Influenza A Virus, H3N2 Subtype
6
2007
61
2.110
Why?
Influenza Vaccines
8
2008
269
2.060
Why?
Lung
12
1996
1148
2.010
Why?
Mice, Inbred C57BL
34
1995
1700
1.970
Why?
Mice
63
1987
6206
1.880
Why?
B-Lymphocytes
11
1996
479
1.620
Why?
Antibodies, Viral
14
1989
456
1.590
Why?
Cell Movement
7
1995
378
1.490
Why?
Antigens, Viral
4
2001
144
1.430
Why?
Lymphocyte Activation
12
1991
414
1.320
Why?
Animals
65
1987
16416
1.320
Why?
Spleen
9
1994
343
1.210
Why?
Orthomyxoviridae
4
1997
59
1.090
Why?
T-Lymphocyte Subsets
4
2006
109
1.050
Why?
T-Lymphocytes
12
1987
564
1.040
Why?
Influenza A Virus, H5N1 Subtype
2
2010
27
0.990
Why?
Pandemics
2
2010
10
0.980
Why?
Collagen
2
2004
301
0.950
Why?
Killer Cells, Natural
3
2006
124
0.940
Why?
Lymphocyte Subsets
2
2009
29
0.910
Why?
Immunity, Cellular
3
1998
135
0.910
Why?
Influenza B virus
1
2012
42
0.840
Why?
Genetic Drift
1
2011
3
0.830
Why?
Cross Protection
1
2011
3
0.830
Why?
Cross Reactions
5
2009
115
0.810
Why?
Vaccinia
2
2006
13
0.750
Why?
Interleukins
1
2010
64
0.730
Why?
Antigens, CD95
2
1997
21
0.730
Why?
Interferon-gamma
7
1999
341
0.720
Why?
Blood
1
2009
96
0.710
Why?
Membrane Glycoproteins
3
1997
376
0.630
Why?
Receptors, Tumor Necrosis Factor, Type II
1
2007
8
0.630
Why?
Herpesviridae Infections
3
2000
71
0.630
Why?
Liver
4
1998
884
0.620
Why?
Female
27
1987
20222
0.620
Why?
Integrin alpha2beta1
1
2007
9
0.610
Why?
Histocompatibility Antigens Class I
4
1996
93
0.590
Why?
Histocompatibility Antigens Class II
5
1987
190
0.590
Why?
Smallpox
1
2006
14
0.580
Why?
Smallpox Vaccine
1
2006
10
0.580
Why?
Respiratory Mucosa
1
2007
82
0.570
Why?
Mice, Knockout
13
1996
922
0.550
Why?
Disease Models, Animal
5
1996
974
0.550
Why?
Apoptosis
3
2003
855
0.540
Why?
Immunoglobulin G
5
2003
494
0.540
Why?
Mice, Inbred BALB C
10
1987
625
0.540
Why?
Pneumonia, Viral
3
1997
22
0.540
Why?
Immunoglobulin M
3
1996
150
0.510
Why?
Gammaherpesvirinae
2
2000
6
0.500
Why?
Mice, Transgenic
9
2000
770
0.500
Why?
Antibody Formation
3
2006
178
0.490
Why?
Lymph Nodes
6
1996
215
0.470
Why?
Adoptive Transfer
4
2001
28
0.450
Why?
Interleukin-2
7
1996
203
0.440
Why?
Peptide Fragments
4
1994
307
0.440
Why?
Flow Cytometry
8
1994
603
0.430
Why?
Hemagglutination Inhibition Tests
2
2011
74
0.410
Why?
Antibodies, Neutralizing
2
2011
34
0.410
Why?
Immunophenotyping
4
1995
126
0.390
Why?
Encephalomyelitis, Autoimmune, Experimental
4
1987
13
0.380
Why?
Leukocytes, Mononuclear
2
2008
112
0.350
Why?
Respirovirus
1
1998
9
0.340
Why?
Cell Proliferation
3
2006
520
0.340
Why?
Respirovirus Infections
1
1998
61
0.330
Why?
Humans
22
1994
37165
0.320
Why?
Bone Marrow Cells
4
1998
222
0.320
Why?
Cell Separation
2
2007
230
0.310
Why?
Vaccinia virus
2
2006
56
0.310
Why?
Receptors, Antigen, T-Cell
4
1996
68
0.300
Why?
Kupffer Cells
2
2006
20
0.290
Why?
Agammaglobulinemia
1
1996
15
0.290
Why?
Enzyme-Linked Immunosorbent Assay
5
1996
472
0.290
Why?
Cell Communication
2
2003
140
0.280
Why?
Adult
9
2006
11572
0.270
Why?
Lymphocytes
4
1994
298
0.270
Why?
Milk Proteins
3
1999
15
0.260
Why?
Cell Survival
5
2003
559
0.260
Why?
Organ Specificity
2
2003
165
0.260
Why?
Cell Line
6
1994
1623
0.260
Why?
Male
9
1996
20139
0.250
Why?
Cell Differentiation
6
1998
1127
0.250
Why?
Time Factors
4
1995
3234
0.250
Why?
Kinetics
3
2000
1471
0.250
Why?
Vaccines, Synthetic
1
1994
88
0.240
Why?
Ovalbumin
2
2001
52
0.240
Why?
Viral Load
2
2010
141
0.240
Why?
Middle Aged
6
2006
10013
0.240
Why?
Amino Acid Sequence
5
1994
1227
0.230
Why?
Cytokines
5
1998
575
0.230
Why?
Molecular Sequence Data
6
1994
2046
0.230
Why?
DNA-Binding Proteins
6
1998
691
0.230
Why?
Virulence
2
2009
153
0.230
Why?
Epitopes, T-Lymphocyte
2
2009
33
0.230
Why?
Malaria
2
2009
22
0.230
Why?
Repressor Proteins
3
1999
178
0.220
Why?
Hematopoietic Stem Cells
3
1998
200
0.220
Why?
Hemagglutination Tests
1
2012
25
0.220
Why?
Integrins
2
2009
48
0.220
Why?
Chemokines
2
2004
112
0.210
Why?
Encephalomyocarditis virus
2
1989
8
0.210
Why?
Ki-67 Antigen
1
2012
29
0.210
Why?
Antigens, Differentiation, T-Lymphocyte
2
1989
35
0.210
Why?
Virus Diseases
2
1997
73
0.210
Why?
Recombinant Proteins
2
2009
770
0.210
Why?
Models, Theoretical
2
2009
194
0.210
Why?
Antigen Presentation
1
2012
77
0.210
Why?
Encephalomyelitis
1
1991
4
0.200
Why?
Poliomyelitis
1
1991
5
0.200
Why?
Cell Cycle
4
1998
253
0.200
Why?
Lectins, C-Type
1
2011
23
0.200
Why?
Neutralization Tests
1
2011
128
0.200
Why?
Young Adult
3
2008
1084
0.200
Why?
Liver Transplantation
3
2007
244
0.200
Why?
Cyclooxygenase 2
2
2009
230
0.200
Why?
Models, Immunological
1
2011
62
0.200
Why?
Phenotype
3
1998
756
0.200
Why?
Vaccination
3
1996
254
0.200
Why?
Proteasome Endopeptidase Complex
1
2011
70
0.190
Why?
Epithelial Cells
2
2010
332
0.190
Why?
Microarray Analysis
1
2010
37
0.190
Why?
Antigens, CD27
1
2010
9
0.190
Why?
Receptors, Interleukin
1
2010
10
0.190
Why?
T-Lymphocytes, Regulatory
1
1991
51
0.190
Why?
Cell Count
1
2011
287
0.190
Why?
Antibody-Producing Cells
2
2000
32
0.190
Why?
Lymphoid Tissue
2
1997
48
0.190
Why?
Biosensing Techniques
1
2010
33
0.190
Why?
Cytopathogenic Effect, Viral
1
2010
28
0.190
Why?
Immunity, Innate
1
2011
103
0.180
Why?
Half-Life
1
2010
104
0.180
Why?
Pore Forming Cytotoxic Proteins
2
1997
9
0.180
Why?
Perforin
2
1997
8
0.180
Why?
Hong Kong
1
2009
22
0.180
Why?
Immunity, Humoral
1
2009
17
0.180
Why?
T-Lymphocytes, Helper-Inducer
2
2006
92
0.180
Why?
MAP Kinase Kinase Kinases
1
2010
47
0.180
Why?
Cyclooxygenase 2 Inhibitors
1
2009
62
0.180
Why?
Blood Platelets
1
2012
281
0.180
Why?
Ibuprofen
1
2009
10
0.170
Why?
4-1BB Ligand
1
2009
1
0.170
Why?
Antigens, CD
1
2011
254
0.170
Why?
Toll-Like Receptor 9
1
2009
12
0.170
Why?
T-Lymphocytes, Cytotoxic
1
2010
147
0.170
Why?
Plasmodium falciparum
1
2009
20
0.170
Why?
Body Weight
1
2010
337
0.170
Why?
Inflammation
2
2007
544
0.170
Why?
Cells, Cultured
8
1995
2589
0.170
Why?
Up-Regulation
1
2011
375
0.170
Why?
Peptides
1
2011
293
0.170
Why?
Protein C
1
2009
47
0.170
Why?
Cytotoxicity, Immunologic
2
1997
119
0.170
Why?
Cyclooxygenase Inhibitors
1
2009
66
0.170
Why?
Oligodeoxyribonucleotides
1
2009
141
0.160
Why?
B-Lymphocyte Subsets
1
2009
68
0.160
Why?
Cell Adhesion
3
1995
270
0.160
Why?
P-Glycoprotein
2
1998
66
0.160
Why?
Integrin alpha1
1
2007
1
0.160
Why?
Anti-Inflammatory Agents, Non-Steroidal
1
2009
93
0.160
Why?
Survival Analysis
1
2010
589
0.160
Why?
Influenza A Virus, H2N2 Subtype
1
2007
3
0.160
Why?
Antigens, CD28
1
2007
35
0.160
Why?
Cell Aggregation
1
2007
26
0.150
Why?
HLA-DR1 Antigen
1
2007
4
0.150
Why?
Hemagglutinins, Viral
1
2007
21
0.150
Why?
Trans-Activators
3
1999
366
0.150
Why?
Transcription, Genetic
1
2011
824
0.150
Why?
Neutrophils
1
2009
313
0.140
Why?
Hepatitis
1
2006
16
0.140
Why?
Gene Expression Regulation, Developmental
2
1999
358
0.140
Why?
Vaccines, Subunit
1
2006
12
0.140
Why?
Antibodies, Monoclonal
4
1987
748
0.140
Why?
Viral Plaque Assay
1
2005
32
0.140
Why?
Monocytes
1
2007
317
0.130
Why?
Macrophages
1
2007
347
0.130
Why?
Dogs
1
2005
492
0.130
Why?
Bacterial Infections
1
2006
129
0.130
Why?
Hypersensitivity
1
2004
47
0.120
Why?
Immunocompetence
1
2004
30
0.120
Why?
Transcription Factors
2
1999
698
0.120
Why?
In Situ Nick-End Labeling
1
2004
96
0.120
Why?
Immunoglobulin A
1
2003
88
0.120
Why?
Ligands
3
2006
294
0.120
Why?
Virus Replication
3
1991
307
0.110
Why?
Bone Marrow Transplantation
2
1999
201
0.110
Why?
Adolescent
3
2006
5044
0.110
Why?
Lung Diseases
1
2004
224
0.110
Why?
Genes, T-Cell Receptor
1
2001
1
0.110
Why?
Egg Proteins
1
2001
5
0.110
Why?
Rhadinovirus
1
2001
3
0.110
Why?
Retroviridae
2
1998
78
0.110
Why?
Mice, Inbred Strains
4
1987
247
0.110
Why?
DNA, Recombinant
1
2001
41
0.110
Why?
Erythropoiesis
2
1998
63
0.100
Why?
Kidney
1
2005
589
0.100
Why?
Lymphocyte Cooperation
2
1998
25
0.100
Why?
Virus Latency
1
2001
15
0.100
Why?
Chimera
1
2001
35
0.100
Why?
Antigens, CD44
2
1995
16
0.100
Why?
Transfection
3
1998
887
0.100
Why?
Gene Targeting
1
2000
70
0.090
Why?
Carrier Proteins
3
1995
446
0.090
Why?
Lymphocyte Depletion
2
1995
64
0.090
Why?
Immunohistochemistry
1
2004
1082
0.090
Why?
DNA, Viral
1
2001
310
0.090
Why?
Protein-Tyrosine Kinases
2
1998
180
0.090
Why?
Antibody Specificity
1
2000
108
0.090
Why?
Lymphocyte Count
2
1996
56
0.090
Why?
Tissue Distribution
3
1997
240
0.090
Why?
Convalescence
1
1998
17
0.090
Why?
Myeloproliferative Disorders
1
1998
18
0.080
Why?
Parainfluenza Virus 1, Human
2
1995
36
0.080
Why?
Lymphoproliferative Disorders
1
1998
30
0.080
Why?
Receptors, Cytokine
1
1998
9
0.080
Why?
CD4 Lymphocyte Count
1
1998
160
0.080
Why?
Mice, Inbred MRL lpr
1
1997
1
0.080
Why?
Thymus Gland
4
1998
144
0.080
Why?
Radiation Chimera
1
1997
15
0.080
Why?
Intracellular Signaling Peptides and Proteins
1
1999
141
0.080
Why?
Hematopoietic Stem Cell Transplantation
1
1998
133
0.070
Why?
Immunoglobulin mu-Chains
1
1996
10
0.070
Why?
Germinal Center
1
1996
17
0.070
Why?
Acute Disease
1
1998
591
0.070
Why?
Tumor Necrosis Factor-alpha
2
1991
694
0.070
Why?
Crosses, Genetic
1
1996
58
0.070
Why?
Immunity
1
1997
65
0.070
Why?
Immunoglobulin Variable Region
1
1996
43
0.070
Why?
Proteins
1
1999
470
0.070
Why?
Signal Transduction
3
1998
1629
0.070
Why?
Bone Marrow
1
1997
292
0.070
Why?
Proto-Oncogene Proteins
1
1998
301
0.070
Why?
Suppressor of Cytokine Signaling Proteins
3
1999
15
0.070
Why?
STAT5 Transcription Factor
3
1999
9
0.070
Why?
Dendritic Cells
1
1996
117
0.060
Why?
Mice, Mutant Strains
3
1999
129
0.060
Why?
HLA-DR Antigens
1
1994
55
0.060
Why?
Hematopoiesis
3
1998
129
0.060
Why?
Central Nervous System
1
1995
117
0.060
Why?
Autoimmune Diseases
1
1994
87
0.060
Why?
Mice, Congenic
1
2012
7
0.060
Why?
Plasmodium berghei
1
2012
6
0.050
Why?
Lung Transplantation
1
2012
12
0.050
Why?
Receptors, Lymphocyte Homing
3
1995
11
0.050
Why?
Cell Division
3
1998
773
0.050
Why?
Transforming Growth Factor beta
1
1995
411
0.050
Why?
Picornaviridae Infections
1
1991
11
0.050
Why?
Fibroblasts
2
1998
545
0.050
Why?
Antigen-Presenting Cells
2
1995
104
0.050
Why?
Viremia
1
1991
36
0.050
Why?
Leukocyte Count
1
1991
162
0.050
Why?
Luminescent Measurements
1
2011
50
0.050
Why?
Encephalitis
1
1991
56
0.050
Why?
Antigens
1
2011
102
0.050
Why?
Antigens, CD8
2
1989
30
0.050
Why?
Disease Outbreaks
1
2010
115
0.040
Why?
Enterovirus Infections
1
1989
28
0.040
Why?
Models, Biological
2
1999
1029
0.040
Why?
Epitopes, B-Lymphocyte
1
2009
6
0.040
Why?
Malaria Vaccines
1
2009
3
0.040
Why?
Aluminum Hydroxide
1
2009
13
0.040
Why?
Clinical Trials, Phase I as Topic
1
2009
11
0.040
Why?
Antigens, CD137
1
2009
1
0.040
Why?
CpG Islands
1
2009
28
0.040
Why?
Cyclooxygenase 1
1
2009
71
0.040
Why?
Administration, Intranasal
1
2009
61
0.040
Why?
Immunization, Secondary
1
2009
72
0.040
Why?
Immunodominant Epitopes
1
2009
26
0.040
Why?
Pyrazoles
1
2009
59
0.040
Why?
Demyelinating Diseases
1
1989
78
0.040
Why?
Respiratory Function Tests
1
2009
129
0.040
Why?
Disease Susceptibility
2
1987
80
0.040
Why?
Interleukin-4
2
1999
160
0.040
Why?
Measles virus
1
2007
9
0.040
Why?
Tumor Escape
1
2007
2
0.040
Why?
Adjuvants, Immunologic
1
2009
118
0.040
Why?
Clone Cells
2
1996
188
0.040
Why?
Cancer Vaccines
1
2007
32
0.040
Why?
Macrophage Activation
1
2007
58
0.040
Why?
Antiviral Agents
1
2009
170
0.040
Why?
Isoantibodies
1
1987
58
0.040
Why?
Animals, Newborn
2
1999
502
0.040
Why?
HIV
1
2007
83
0.040
Why?
Herpesvirus 1, Human
1
2007
67
0.040
Why?
Whole-Body Irradiation
1
2007
87
0.040
Why?
Computer Simulation
1
2009
304
0.040
Why?
Viral Vaccines
1
2007
105
0.040
Why?
Predictive Value of Tests
1
2009
609
0.040
Why?
Proto-Oncogene Proteins c-bcl-2
1
2007
116
0.040
Why?
Sequence Homology, Amino Acid
1
2007
293
0.040
Why?
Intracellular Fluid
1
2006
42
0.040
Why?
Alanine Transaminase
1
2006
24
0.040
Why?
Listeria monocytogenes
1
2006
6
0.040
Why?
Dose-Response Relationship, Drug
2
1999
1142
0.030
Why?
Tetanus Toxoid
1
2006
41
0.030
Why?
Homeostasis
2
1996
177
0.030
Why?
Leukocytes
2
1995
192
0.030
Why?
Hepatocytes
1
2006
57
0.030
Why?
Dimerization
1
2006
167
0.030
Why?
Phosphorylation
2
1998
839
0.030
Why?
Bronchial Hyperreactivity
1
2004
22
0.030
Why?
DNA
2
1999
862
0.030
Why?
Th1 Cells
1
2004
70
0.030
Why?
Severity of Illness Index
1
2009
943
0.030
Why?
Th2 Cells
1
2004
91
0.030
Why?
Antigens, CD40
1
2003
55
0.030
Why?
Gene Expression Regulation
1
2009
895
0.030
Why?
Alleles
2
1987
206
0.030
Why?
Base Sequence
1
2006
1721
0.020
Why?
Neoplasms
1
2007
743
0.020
Why?
Janus Kinase 3
1
1999
4
0.020
Why?
Receptors, Interleukin-4
1
1999
4
0.020
Why?
Receptors, Interleukin-2
1
1999
30
0.020
Why?
Antigens, CD3
1
1999
36
0.020
Why?
Autoantibodies
1
2000
109
0.020
Why?
Embryo, Mammalian
1
2000
195
0.020
Why?
Interleukin-7
1
1999
10
0.020
Why?
RNA-Binding Proteins
1
2000
130
0.020
Why?
Harvey murine sarcoma virus
1
1998
1
0.020
Why?
Stem Cell Factor
1
1998
18
0.020
Why?
Genes, MDR
1
1998
10
0.020
Why?
Models, Genetic
1
1999
162
0.020
Why?
X Chromosome
1
1998
37
0.020
Why?
Thymus Neoplasms
1
1998
23
0.020
Why?
Mutagenesis
1
1999
142
0.020
Why?
Interleukin-3
1
1998
43
0.020
Why?
In Situ Hybridization
1
1999
332
0.020
Why?
Interferon Regulatory Factor-1
1
1998
4
0.020
Why?
Thrombopoietin
1
1998
7
0.020
Why?
Colony-Stimulating Factors
1
1998
27
0.020
Why?
Janus Kinase 2
1
1998
15
0.020
Why?
Transduction, Genetic
1
1998
130
0.020
Why?
CD40 Ligand
1
1998
93
0.020
Why?
Graft Survival
1
1998
151
0.020
Why?
Lymphoma
1
1998
163
0.020
Why?
Respiratory Tract Diseases
1
1997
42
0.020
Why?
Tyrosine
1
1998
145
0.020
Why?
Gene Transfer Techniques
1
1998
154
0.020
Why?
Conalbumin
1
1996
3
0.020
Why?
Phosphoproteins
1
1998
181
0.020
Why?
Indicator Dilution Techniques
1
1996
5
0.020
Why?
Polymerase Chain Reaction
1
1998
597
0.020
Why?
Genetic Vectors
1
1998
349
0.020
Why?
Interleukin-6
1
1998
339
0.020
Why?
Age Factors
1
1999
1152
0.020
Why?
Dose-Response Relationship, Immunologic
1
1995
57
0.020
Why?
Antigens, CD45
1
1995
38
0.020
Why?
Antigens, CD4
1
1995
39
0.020
Why?
Immunosuppressive Agents
1
1996
206
0.020
Why?
Blood-Brain Barrier
1
1995
110
0.020
Why?
Down-Regulation
1
1995
246
0.010
Why?
Receptors, Cell Surface
1
1995
217
0.010
Why?
Regression Analysis
1
1995
539
0.010
Why?
Picornaviridae
1
1991
1
0.010
Why?
Endothelium, Vascular
1
1995
454
0.010
Why?
RNA, Messenger
1
1998
1893
0.010
Why?
Paralysis
1
1989
55
0.010
Why?
Astrocytes
1
1991
291
0.010
Why?
Immunization, Passive
1
1987
65
0.010
Why?
Brain
1
1991
1228
0.010
Why?

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