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David Topham

Concepts (367)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of pubs Most recent pub Pubs by all authors Concept score Why?
Orthomyxoviridae Infections
21
1995
99
6.580
Why?
CD8-Positive T-Lymphocytes
20
1996
223
5.120
Why?
CD4-Positive T-Lymphocytes
23
1991
299
4.400
Why?
Immunologic Memory
18
1996
132
2.900
Why?
Influenza A Virus, H1N1 Subtype
7
2006
85
2.600
Why?
Influenza A virus
14
1995
222
2.440
Why?
Integrin alpha1beta1
4
2004
6
2.320
Why?
Hemagglutinin Glycoproteins, Influenza Virus
5
2008
43
2.310
Why?
Influenza, Human
8
2006
329
2.100
Why?
Influenza Vaccines
8
2008
239
2.010
Why?
Influenza A Virus, H3N2 Subtype
6
2007
64
2.000
Why?
Lung
12
1996
1132
1.930
Why?
Mice, Inbred C57BL
34
1995
1613
1.920
Why?
Mice
63
1987
5900
1.860
Why?
B-Lymphocytes
11
1996
460
1.560
Why?
Antibodies, Viral
14
1989
472
1.490
Why?
Cell Movement
7
1995
352
1.430
Why?
Antigens, Viral
4
2001
151
1.340
Why?
Animals
65
1987
15647
1.300
Why?
Lymphocyte Activation
12
1991
407
1.260
Why?
Spleen
9
1994
338
1.150
Why?
Orthomyxoviridae
4
1997
57
1.020
Why?
T-Lymphocytes
12
1987
546
1.000
Why?
T-Lymphocyte Subsets
4
2006
111
1.000
Why?
Influenza A Virus, H5N1 Subtype
2
2010
26
0.940
Why?
Pandemics
2
2010
10
0.930
Why?
Collagen
2
2004
270
0.910
Why?
Killer Cells, Natural
3
2006
122
0.890
Why?
Immunity, Cellular
3
1998
135
0.860
Why?
Lymphocyte Subsets
2
2009
28
0.860
Why?
Influenza B virus
1
2012
43
0.790
Why?
Genetic Drift
1
2011
3
0.790
Why?
Cross Protection
1
2011
3
0.790
Why?
Cross Reactions
5
2009
110
0.770
Why?
Vaccinia
2
2006
13
0.710
Why?
Interleukins
1
2010
63
0.700
Why?
Antigens, CD95
2
1997
21
0.690
Why?
Interferon-gamma
7
1999
340
0.690
Why?
Blood
1
2009
92
0.670
Why?
Female
27
1987
19061
0.620
Why?
Membrane Glycoproteins
3
1997
350
0.610
Why?
Liver
4
1998
870
0.600
Why?
Herpesviridae Infections
3
2000
71
0.600
Why?
Receptors, Tumor Necrosis Factor, Type II
1
2007
8
0.600
Why?
Integrin alpha2beta1
1
2007
8
0.580
Why?
Histocompatibility Antigens Class I
4
1996
92
0.560
Why?
Histocompatibility Antigens Class II
5
1987
187
0.560
Why?
Respiratory Mucosa
1
2007
81
0.540
Why?
Smallpox
1
2006
14
0.540
Why?
Smallpox Vaccine
1
2006
10
0.540
Why?
Mice, Knockout
13
1996
857
0.540
Why?
Apoptosis
3
2003
782
0.540
Why?
Disease Models, Animal
5
1996
908
0.530
Why?
Immunoglobulin G
5
2003
491
0.510
Why?
Mice, Inbred BALB C
10
1987
616
0.510
Why?
Pneumonia, Viral
3
1997
28
0.500
Why?
Immunoglobulin M
3
1996
146
0.480
Why?
Mice, Transgenic
9
2000
735
0.480
Why?
Gammaherpesvirinae
2
2000
6
0.470
Why?
Antibody Formation
3
2006
176
0.460
Why?
Lymph Nodes
6
1996
207
0.450
Why?
Adoptive Transfer
4
2001
29
0.420
Why?
Peptide Fragments
4
1994
277
0.420
Why?
Interleukin-2
7
1996
198
0.420
Why?
Flow Cytometry
8
1994
597
0.410
Why?
Hemagglutination Inhibition Tests
2
2011
74
0.390
Why?
Antibodies, Neutralizing
2
2011
31
0.390
Why?
Immunophenotyping
4
1995
123
0.370
Why?
Encephalomyelitis, Autoimmune, Experimental
4
1987
13
0.360
Why?
Cell Proliferation
3
2006
480
0.330
Why?
Leukocytes, Mononuclear
2
2008
109
0.330
Why?
Respirovirus
1
1998
11
0.320
Why?
Humans
22
1994
35000
0.320
Why?
Respirovirus Infections
1
1998
65
0.310
Why?
Bone Marrow Cells
4
1998
220
0.300
Why?
Cell Separation
2
2007
224
0.300
Why?
Vaccinia virus
2
2006
53
0.290
Why?
Receptors, Antigen, T-Cell
4
1996
68
0.280
Why?
Kupffer Cells
2
2006
19
0.280
Why?
Enzyme-Linked Immunosorbent Assay
5
1996
459
0.280
Why?
Agammaglobulinemia
1
1996
16
0.280
Why?
Cell Communication
2
2003
135
0.270
Why?
Adult
9
2006
10906
0.270
Why?
Lymphocytes
4
1994
293
0.260
Why?
Male
9
1996
18870
0.250
Why?
Cell Differentiation
6
1998
1021
0.250
Why?
Cell Line
6
1994
1554
0.250
Why?
Cell Survival
5
2003
537
0.250
Why?
Milk Proteins
3
1999
14
0.250
Why?
Organ Specificity
2
2003
158
0.240
Why?
Time Factors
4
1995
3047
0.240
Why?
Kinetics
3
2000
1377
0.240
Why?
Middle Aged
6
2006
9461
0.230
Why?
Vaccines, Synthetic
1
1994
89
0.230
Why?
Ovalbumin
2
2001
54
0.230
Why?
Amino Acid Sequence
5
1994
1198
0.220
Why?
Cytokines
5
1998
555
0.220
Why?
Viral Load
2
2010
138
0.220
Why?
Molecular Sequence Data
6
1994
1993
0.220
Why?
DNA-Binding Proteins
6
1998
661
0.220
Why?
Epitopes, T-Lymphocyte
2
2009
32
0.220
Why?
Repressor Proteins
3
1999
171
0.210
Why?
Virulence
2
2009
152
0.210
Why?
Malaria
2
2009
22
0.210
Why?
Hematopoietic Stem Cells
3
1998
196
0.210
Why?
Hemagglutination Tests
1
2012
25
0.210
Why?
Integrins
2
2009
45
0.210
Why?
Chemokines
2
2004
112
0.200
Why?
Ki-67 Antigen
1
2012
29
0.200
Why?
Encephalomyocarditis virus
2
1989
8
0.200
Why?
Recombinant Proteins
2
2009
706
0.200
Why?
Antigens, Differentiation, T-Lymphocyte
2
1989
34
0.200
Why?
Vaccination
3
1996
197
0.200
Why?
Models, Theoretical
2
2009
190
0.200
Why?
Young Adult
3
2008
1013
0.190
Why?
Antigen Presentation
1
2012
77
0.190
Why?
Cell Cycle
4
1998
247
0.190
Why?
Virus Diseases
2
1997
82
0.190
Why?
Encephalomyelitis
1
1991
5
0.190
Why?
Poliomyelitis
1
1991
5
0.190
Why?
Lectins, C-Type
1
2011
20
0.190
Why?
Cyclooxygenase 2
2
2009
211
0.190
Why?
Phenotype
3
1998
727
0.190
Why?
Neutralization Tests
1
2011
128
0.190
Why?
Liver Transplantation
3
2007
246
0.190
Why?
Models, Immunological
1
2011
62
0.190
Why?
Epithelial Cells
2
2010
324
0.180
Why?
Proteasome Endopeptidase Complex
1
2011
65
0.180
Why?
T-Lymphocytes, Regulatory
1
1991
48
0.180
Why?
Microarray Analysis
1
2010
34
0.180
Why?
Cell Count
1
2011
279
0.180
Why?
Antigens, CD27
1
2010
8
0.180
Why?
Receptors, Interleukin
1
2010
10
0.180
Why?
Antibody-Producing Cells
2
2000
37
0.180
Why?
Biosensing Techniques
1
2010
33
0.180
Why?
Immunity, Innate
1
2011
103
0.180
Why?
Cytopathogenic Effect, Viral
1
2010
27
0.180
Why?
Lymphoid Tissue
2
1997
58
0.170
Why?
Half-Life
1
2010
98
0.170
Why?
Pore Forming Cytotoxic Proteins
2
1997
10
0.170
Why?
Perforin
2
1997
9
0.170
Why?
Hong Kong
1
2009
23
0.170
Why?
MAP Kinase Kinase Kinases
1
2010
38
0.170
Why?
T-Lymphocytes, Helper-Inducer
2
2006
94
0.170
Why?
Immunity, Humoral
1
2009
18
0.170
Why?
Cells, Cultured
8
1995
2367
0.170
Why?
Blood Platelets
1
2012
271
0.170
Why?
Cyclooxygenase 2 Inhibitors
1
2009
61
0.170
Why?
Inflammation
2
2007
518
0.170
Why?
Antigens, CD
1
2011
240
0.170
Why?
T-Lymphocytes, Cytotoxic
1
2010
130
0.170
Why?
Up-Regulation
1
2011
344
0.160
Why?
Ibuprofen
1
2009
10
0.160
Why?
4-1BB Ligand
1
2009
1
0.160
Why?
Toll-Like Receptor 9
1
2009
10
0.160
Why?
Body Weight
1
2010
328
0.160
Why?
Plasmodium falciparum
1
2009
20
0.160
Why?
Protein C
1
2009
31
0.160
Why?
Peptides
1
2011
277
0.160
Why?
Cyclooxygenase Inhibitors
1
2009
63
0.160
Why?
Cytotoxicity, Immunologic
2
1997
116
0.160
Why?
Cell Adhesion
3
1995
253
0.160
Why?
Oligodeoxyribonucleotides
1
2009
138
0.160
Why?
B-Lymphocyte Subsets
1
2009
67
0.150
Why?
P-Glycoprotein
2
1998
63
0.150
Why?
Anti-Inflammatory Agents, Non-Steroidal
1
2009
89
0.150
Why?
Survival Analysis
1
2010
575
0.150
Why?
Integrin alpha1
1
2007
1
0.150
Why?
Trans-Activators
3
1999
343
0.150
Why?
Influenza A Virus, H2N2 Subtype
1
2007
3
0.150
Why?
Antigens, CD28
1
2007
34
0.150
Why?
Cell Aggregation
1
2007
27
0.150
Why?
HLA-DR1 Antigen
1
2007
4
0.150
Why?
Hemagglutinins, Viral
1
2007
21
0.140
Why?
Transcription, Genetic
1
2011
795
0.140
Why?
Neutrophils
1
2009
307
0.140
Why?
Antibodies, Monoclonal
4
1987
725
0.140
Why?
Gene Expression Regulation, Developmental
2
1999
329
0.140
Why?
Hepatitis
1
2006
16
0.130
Why?
Vaccines, Subunit
1
2006
11
0.130
Why?
Viral Plaque Assay
1
2005
27
0.130
Why?
Monocytes
1
2007
294
0.130
Why?
Macrophages
1
2007
329
0.120
Why?
Dogs
1
2005
465
0.120
Why?
Bacterial Infections
1
2006
127
0.120
Why?
Hypersensitivity
1
2004
46
0.120
Why?
Transcription Factors
2
1999
659
0.120
Why?
Immunocompetence
1
2004
30
0.110
Why?
In Situ Nick-End Labeling
1
2004
89
0.110
Why?
Adolescent
3
2006
4513
0.110
Why?
Immunoglobulin A
1
2003
88
0.110
Why?
Ligands
3
2006
287
0.110
Why?
Virus Replication
3
1991
287
0.110
Why?
Bone Marrow Transplantation
2
1999
189
0.110
Why?
Lung Diseases
1
2004
224
0.100
Why?
Retroviridae
2
1998
72
0.100
Why?
Genes, T-Cell Receptor
1
2001
1
0.100
Why?
Egg Proteins
1
2001
6
0.100
Why?
Rhadinovirus
1
2001
3
0.100
Why?
Mice, Inbred Strains
4
1987
238
0.100
Why?
DNA, Recombinant
1
2001
40
0.100
Why?
Kidney
1
2005
581
0.100
Why?
Erythropoiesis
2
1998
65
0.100
Why?
Lymphocyte Cooperation
2
1998
25
0.100
Why?
Transfection
3
1998
833
0.100
Why?
Virus Latency
1
2001
14
0.100
Why?
Chimera
1
2001
34
0.100
Why?
Antigens, CD44
2
1995
16
0.100
Why?
Carrier Proteins
3
1995
410
0.090
Why?
Immunohistochemistry
1
2004
1024
0.090
Why?
Gene Targeting
1
2000
69
0.090
Why?
DNA, Viral
1
2001
288
0.090
Why?
Lymphocyte Depletion
2
1995
60
0.090
Why?
Protein-Tyrosine Kinases
2
1998
164
0.090
Why?
Antibody Specificity
1
2000
104
0.090
Why?
Lymphocyte Count
2
1996
52
0.090
Why?
Tissue Distribution
3
1997
228
0.080
Why?
Convalescence
1
1998
19
0.080
Why?
Myeloproliferative Disorders
1
1998
17
0.080
Why?
Parainfluenza Virus 1, Human
2
1995
37
0.080
Why?
Lymphoproliferative Disorders
1
1998
30
0.080
Why?
Receptors, Cytokine
1
1998
7
0.080
Why?
CD4 Lymphocyte Count
1
1998
147
0.080
Why?
Thymus Gland
4
1998
143
0.080
Why?
Mice, Inbred MRL lpr
1
1997
1
0.080
Why?
Radiation Chimera
1
1997
16
0.080
Why?
Intracellular Signaling Peptides and Proteins
1
1999
130
0.070
Why?
Tumor Necrosis Factor-alpha
2
1991
627
0.070
Why?
Hematopoietic Stem Cell Transplantation
1
1998
124
0.070
Why?
Immunoglobulin mu-Chains
1
1996
10
0.070
Why?
Signal Transduction
3
1998
1465
0.070
Why?
Acute Disease
1
1998
570
0.070
Why?
Germinal Center
1
1996
16
0.070
Why?
Crosses, Genetic
1
1996
55
0.070
Why?
Immunity
1
1997
65
0.070
Why?
Proteins
1
1999
435
0.070
Why?
Immunoglobulin Variable Region
1
1996
42
0.070
Why?
Proto-Oncogene Proteins
1
1998
261
0.060
Why?
Bone Marrow
1
1997
282
0.060
Why?
Suppressor of Cytokine Signaling Proteins
3
1999
13
0.060
Why?
STAT5 Transcription Factor
3
1999
11
0.060
Why?
Dendritic Cells
1
1996
110
0.060
Why?
Mice, Mutant Strains
3
1999
119
0.060
Why?
HLA-DR Antigens
1
1994
49
0.060
Why?
Hematopoiesis
3
1998
128
0.060
Why?
Central Nervous System
1
1995
110
0.060
Why?
Autoimmune Diseases
1
1994
84
0.060
Why?
Mice, Congenic
1
2012
7
0.050
Why?
Plasmodium berghei
1
2012
6
0.050
Why?
Transforming Growth Factor beta
1
1995
362
0.050
Why?
Lung Transplantation
1
2012
10
0.050
Why?
Cell Division
3
1998
735
0.050
Why?
Receptors, Lymphocyte Homing
3
1995
11
0.050
Why?
Fibroblasts
2
1998
514
0.050
Why?
Picornaviridae Infections
1
1991
11
0.050
Why?
Viremia
1
1991
26
0.050
Why?
Antigen-Presenting Cells
2
1995
104
0.050
Why?
Leukocyte Count
1
1991
152
0.050
Why?
Luminescent Measurements
1
2011
47
0.050
Why?
Encephalitis
1
1991
55
0.050
Why?
Antigens
1
2011
101
0.050
Why?
Antigens, CD8
2
1989
30
0.040
Why?
Disease Outbreaks
1
2010
109
0.040
Why?
Models, Biological
2
1999
982
0.040
Why?
Enterovirus Infections
1
1989
27
0.040
Why?
Epitopes, B-Lymphocyte
1
2009
6
0.040
Why?
Malaria Vaccines
1
2009
3
0.040
Why?
Aluminum Hydroxide
1
2009
13
0.040
Why?
Clinical Trials, Phase I as Topic
1
2009
11
0.040
Why?
Antigens, CD137
1
2009
1
0.040
Why?
CpG Islands
1
2009
25
0.040
Why?
Cyclooxygenase 1
1
2009
66
0.040
Why?
Administration, Intranasal
1
2009
62
0.040
Why?
Immunodominant Epitopes
1
2009
24
0.040
Why?
Immunization, Secondary
1
2009
68
0.040
Why?
Pyrazoles
1
2009
56
0.040
Why?
Demyelinating Diseases
1
1989
75
0.040
Why?
Respiratory Function Tests
1
2009
121
0.040
Why?
Interleukin-4
2
1999
160
0.040
Why?
Disease Susceptibility
2
1987
77
0.040
Why?
Adjuvants, Immunologic
1
2009
118
0.040
Why?
Measles virus
1
2007
9
0.040
Why?
Tumor Escape
1
2007
2
0.040
Why?
Clone Cells
2
1996
188
0.040
Why?
Cancer Vaccines
1
2007
31
0.040
Why?
Animals, Newborn
2
1999
470
0.040
Why?
Macrophage Activation
1
2007
53
0.040
Why?
Isoantibodies
1
1987
58
0.040
Why?
Antiviral Agents
1
2009
181
0.040
Why?
HIV
1
2007
73
0.040
Why?
Predictive Value of Tests
1
2009
579
0.040
Why?
Herpesvirus 1, Human
1
2007
63
0.040
Why?
Computer Simulation
1
2009
295
0.040
Why?
Whole-Body Irradiation
1
2007
78
0.040
Why?
Viral Vaccines
1
2007
107
0.030
Why?
Proto-Oncogene Proteins c-bcl-2
1
2007
110
0.030
Why?
Sequence Homology, Amino Acid
1
2007
287
0.030
Why?
Intracellular Fluid
1
2006
40
0.030
Why?
Dose-Response Relationship, Drug
2
1999
1085
0.030
Why?
Alanine Transaminase
1
2006
23
0.030
Why?
Listeria monocytogenes
1
2006
7
0.030
Why?
Tetanus Toxoid
1
2006
40
0.030
Why?
Homeostasis
2
1996
171
0.030
Why?
Phosphorylation
2
1998
754
0.030
Why?
Leukocytes
2
1995
191
0.030
Why?
Dimerization
1
2006
154
0.030
Why?
Hepatocytes
1
2006
54
0.030
Why?
DNA
2
1999
831
0.030
Why?
Severity of Illness Index
1
2009
878
0.030
Why?
Bronchial Hyperreactivity
1
2004
23
0.030
Why?
Th1 Cells
1
2004
72
0.030
Why?
Th2 Cells
1
2004
89
0.030
Why?
Antigens, CD40
1
2003
55
0.030
Why?
Gene Expression Regulation
1
2009
848
0.030
Why?
Alleles
2
1987
200
0.030
Why?
Base Sequence
1
2006
1681
0.020
Why?
Neoplasms
1
2007
701
0.020
Why?
Janus Kinase 3
1
1999
3
0.020
Why?
Receptors, Interleukin-4
1
1999
4
0.020
Why?
Receptors, Interleukin-2
1
1999
28
0.020
Why?
Embryo, Mammalian
1
2000
181
0.020
Why?
Antigens, CD3
1
1999
34
0.020
Why?
Autoantibodies
1
2000
109
0.020
Why?
Interleukin-7
1
1999
10
0.020
Why?
RNA-Binding Proteins
1
2000
132
0.020
Why?
Harvey murine sarcoma virus
1
1998
1
0.020
Why?
Models, Genetic
1
1999
157
0.020
Why?
Stem Cell Factor
1
1998
15
0.020
Why?
Genes, MDR
1
1998
9
0.020
Why?
X Chromosome
1
1998
34
0.020
Why?
Mutagenesis
1
1999
130
0.020
Why?
Thymus Neoplasms
1
1998
22
0.020
Why?
In Situ Hybridization
1
1999
293
0.020
Why?
Interleukin-3
1
1998
40
0.020
Why?
Thrombopoietin
1
1998
3
0.020
Why?
Interferon Regulatory Factor-1
1
1998
4
0.020
Why?
Janus Kinase 2
1
1998
13
0.020
Why?
Colony-Stimulating Factors
1
1998
27
0.020
Why?
Transduction, Genetic
1
1998
111
0.020
Why?
CD40 Ligand
1
1998
92
0.020
Why?
Graft Survival
1
1998
145
0.020
Why?
Lymphoma
1
1998
151
0.020
Why?
Tyrosine
1
1998
133
0.020
Why?
Respiratory Tract Diseases
1
1997
44
0.020
Why?
Gene Transfer Techniques
1
1998
145
0.020
Why?
Phosphoproteins
1
1998
148
0.020
Why?
Conalbumin
1
1996
3
0.020
Why?
Genetic Vectors
1
1998
328
0.020
Why?
Indicator Dilution Techniques
1
1996
5
0.020
Why?
Polymerase Chain Reaction
1
1998
586
0.020
Why?
Age Factors
1
1999
1060
0.020
Why?
Interleukin-6
1
1998
314
0.020
Why?
Dose-Response Relationship, Immunologic
1
1995
60
0.020
Why?
Antigens, CD45
1
1995
39
0.020
Why?
Antigens, CD4
1
1995
36
0.020
Why?
Immunosuppressive Agents
1
1996
200
0.010
Why?
Blood-Brain Barrier
1
1995
103
0.010
Why?
Down-Regulation
1
1995
227
0.010
Why?
Receptors, Cell Surface
1
1995
206
0.010
Why?
Regression Analysis
1
1995
489
0.010
Why?
Picornaviridae
1
1991
1
0.010
Why?
Endothelium, Vascular
1
1995
401
0.010
Why?
RNA, Messenger
1
1998
1791
0.010
Why?
Paralysis
1
1989
50
0.010
Why?
Astrocytes
1
1991
267
0.010
Why?
Immunization, Passive
1
1987
66
0.010
Why?
Brain
1
1991
1161
0.010
Why?

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