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David Topham

Concepts (367)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of pubs Most recent pub Pubs by all authors Concept score Why?
Orthomyxoviridae Infections
21
1995
95
6.790
Why?
CD8-Positive T-Lymphocytes
20
1996
224
5.270
Why?
CD4-Positive T-Lymphocytes
23
1991
303
4.520
Why?
Immunologic Memory
18
1996
119
3.030
Why?
Influenza A Virus, H1N1 Subtype
7
2006
85
2.680
Why?
Influenza A virus
14
1995
225
2.520
Why?
Integrin alpha1beta1
4
2004
6
2.410
Why?
Hemagglutinin Glycoproteins, Influenza Virus
5
2008
43
2.390
Why?
Influenza, Human
8
2006
350
2.120
Why?
Influenza A Virus, H3N2 Subtype
6
2007
62
2.060
Why?
Influenza Vaccines
8
2008
264
2.010
Why?
Lung
12
1996
1159
1.960
Why?
Mice, Inbred C57BL
34
1995
1675
1.950
Why?
Mice
63
1987
6111
1.870
Why?
B-Lymphocytes
11
1996
432
1.650
Why?
Antibodies, Viral
14
1989
472
1.540
Why?
Cell Movement
7
1995
361
1.470
Why?
Antigens, Viral
4
2001
149
1.390
Why?
Animals
65
1987
16093
1.310
Why?
Lymphocyte Activation
12
1991
410
1.300
Why?
Spleen
9
1994
341
1.190
Why?
Orthomyxoviridae
4
1997
58
1.060
Why?
T-Lymphocytes
12
1987
550
1.030
Why?
T-Lymphocyte Subsets
4
2006
112
1.030
Why?
Influenza A Virus, H5N1 Subtype
2
2010
26
0.970
Why?
Pandemics
2
2010
10
0.960
Why?
Collagen
2
2004
290
0.940
Why?
Killer Cells, Natural
3
2006
121
0.920
Why?
Immunity, Cellular
3
1998
132
0.890
Why?
Lymphocyte Subsets
2
2009
27
0.890
Why?
Influenza B virus
1
2012
43
0.820
Why?
Genetic Drift
1
2011
3
0.810
Why?
Cross Protection
1
2011
3
0.810
Why?
Cross Reactions
5
2009
108
0.790
Why?
Vaccinia
2
2006
13
0.730
Why?
Interleukins
1
2010
63
0.720
Why?
Antigens, CD95
2
1997
22
0.710
Why?
Interferon-gamma
7
1999
348
0.700
Why?
Blood
1
2009
93
0.690
Why?
Membrane Glycoproteins
3
1997
366
0.620
Why?
Receptors, Tumor Necrosis Factor, Type II
1
2007
8
0.620
Why?
Herpesviridae Infections
3
2000
71
0.620
Why?
Female
27
1987
19838
0.610
Why?
Liver
4
1998
877
0.610
Why?
Integrin alpha2beta1
1
2007
8
0.600
Why?
Histocompatibility Antigens Class I
4
1996
95
0.580
Why?
Histocompatibility Antigens Class II
5
1987
189
0.570
Why?
Respiratory Mucosa
1
2007
81
0.560
Why?
Smallpox
1
2006
14
0.560
Why?
Smallpox Vaccine
1
2006
10
0.560
Why?
Mice, Knockout
13
1996
895
0.550
Why?
Apoptosis
3
2003
823
0.540
Why?
Disease Models, Animal
5
1996
956
0.540
Why?
Immunoglobulin G
5
2003
488
0.530
Why?
Mice, Inbred BALB C
10
1987
632
0.530
Why?
Pneumonia, Viral
3
1997
27
0.520
Why?
Immunoglobulin M
3
1996
141
0.500
Why?
Mice, Transgenic
9
2000
749
0.490
Why?
Gammaherpesvirinae
2
2000
6
0.490
Why?
Antibody Formation
3
2006
179
0.480
Why?
Lymph Nodes
6
1996
206
0.460
Why?
Adoptive Transfer
4
2001
27
0.440
Why?
Interleukin-2
7
1996
198
0.430
Why?
Peptide Fragments
4
1994
282
0.430
Why?
Flow Cytometry
8
1994
603
0.420
Why?
Hemagglutination Inhibition Tests
2
2011
75
0.400
Why?
Antibodies, Neutralizing
2
2011
32
0.400
Why?
Immunophenotyping
4
1995
114
0.380
Why?
Encephalomyelitis, Autoimmune, Experimental
4
1987
13
0.370
Why?
Leukocytes, Mononuclear
2
2008
110
0.340
Why?
Cell Proliferation
3
2006
515
0.330
Why?
Respirovirus
1
1998
11
0.330
Why?
Respirovirus Infections
1
1998
66
0.320
Why?
Humans
22
1994
36274
0.320
Why?
Bone Marrow Cells
4
1998
221
0.310
Why?
Cell Separation
2
2007
231
0.310
Why?
Vaccinia virus
2
2006
53
0.300
Why?
Receptors, Antigen, T-Cell
4
1996
66
0.290
Why?
Agammaglobulinemia
1
1996
12
0.290
Why?
Kupffer Cells
2
2006
20
0.290
Why?
Enzyme-Linked Immunosorbent Assay
5
1996
462
0.290
Why?
Cell Communication
2
2003
139
0.280
Why?
Adult
9
2006
11351
0.270
Why?
Lymphocytes
4
1994
291
0.270
Why?
Milk Proteins
3
1999
14
0.260
Why?
Cell Survival
5
2003
551
0.250
Why?
Cell Line
6
1994
1585
0.250
Why?
Organ Specificity
2
2003
162
0.250
Why?
Male
9
1996
19675
0.250
Why?
Cell Differentiation
6
1998
1093
0.250
Why?
Kinetics
3
2000
1391
0.250
Why?
Time Factors
4
1995
3182
0.250
Why?
Vaccines, Synthetic
1
1994
90
0.240
Why?
Ovalbumin
2
2001
55
0.230
Why?
Middle Aged
6
2006
9837
0.230
Why?
Viral Load
2
2010
135
0.230
Why?
Amino Acid Sequence
5
1994
1195
0.230
Why?
Cytokines
5
1998
565
0.230
Why?
Molecular Sequence Data
6
1994
1988
0.230
Why?
DNA-Binding Proteins
6
1998
685
0.220
Why?
Epitopes, T-Lymphocyte
2
2009
31
0.220
Why?
Virulence
2
2009
153
0.220
Why?
Malaria
2
2009
22
0.220
Why?
Repressor Proteins
3
1999
176
0.220
Why?
Hematopoietic Stem Cells
3
1998
197
0.220
Why?
Hemagglutination Tests
1
2012
24
0.210
Why?
Integrins
2
2009
48
0.210
Why?
Chemokines
2
2004
111
0.210
Why?
Encephalomyocarditis virus
2
1989
8
0.210
Why?
Ki-67 Antigen
1
2012
29
0.210
Why?
Antigens, Differentiation, T-Lymphocyte
2
1989
34
0.210
Why?
Recombinant Proteins
2
2009
723
0.210
Why?
Models, Theoretical
2
2009
192
0.200
Why?
Antigen Presentation
1
2012
76
0.200
Why?
Virus Diseases
2
1997
83
0.200
Why?
Cell Cycle
4
1998
254
0.200
Why?
Encephalomyelitis
1
1991
5
0.200
Why?
Poliomyelitis
1
1991
5
0.200
Why?
Young Adult
3
2008
1059
0.200
Why?
Lectins, C-Type
1
2011
22
0.200
Why?
Neutralization Tests
1
2011
129
0.200
Why?
Liver Transplantation
3
2007
237
0.190
Why?
Vaccination
3
1996
232
0.190
Why?
Cyclooxygenase 2
2
2009
226
0.190
Why?
Models, Immunological
1
2011
61
0.190
Why?
Phenotype
3
1998
763
0.190
Why?
Epithelial Cells
2
2010
327
0.190
Why?
Proteasome Endopeptidase Complex
1
2011
70
0.190
Why?
Microarray Analysis
1
2010
35
0.190
Why?
T-Lymphocytes, Regulatory
1
1991
49
0.190
Why?
Antigens, CD27
1
2010
6
0.190
Why?
Receptors, Interleukin
1
2010
10
0.190
Why?
Cell Count
1
2011
286
0.190
Why?
Antibody-Producing Cells
2
2000
35
0.180
Why?
Lymphoid Tissue
2
1997
47
0.180
Why?
Immunity, Innate
1
2011
98
0.180
Why?
Biosensing Techniques
1
2010
33
0.180
Why?
Cytopathogenic Effect, Viral
1
2010
27
0.180
Why?
Half-Life
1
2010
100
0.180
Why?
Pore Forming Cytotoxic Proteins
2
1997
9
0.180
Why?
Perforin
2
1997
9
0.180
Why?
Hong Kong
1
2009
23
0.180
Why?
T-Lymphocytes, Helper-Inducer
2
2006
91
0.180
Why?
Immunity, Humoral
1
2009
18
0.180
Why?
MAP Kinase Kinase Kinases
1
2010
42
0.180
Why?
Blood Platelets
1
2012
277
0.170
Why?
Cyclooxygenase 2 Inhibitors
1
2009
63
0.170
Why?
Antigens, CD
1
2011
244
0.170
Why?
Cells, Cultured
8
1995
2479
0.170
Why?
T-Lymphocytes, Cytotoxic
1
2010
128
0.170
Why?
Ibuprofen
1
2009
10
0.170
Why?
Inflammation
2
2007
534
0.170
Why?
4-1BB Ligand
1
2009
1
0.170
Why?
Body Weight
1
2010
327
0.170
Why?
Toll-Like Receptor 9
1
2009
12
0.170
Why?
Plasmodium falciparum
1
2009
20
0.170
Why?
Up-Regulation
1
2011
363
0.170
Why?
Protein C
1
2009
31
0.170
Why?
Peptides
1
2011
285
0.170
Why?
Cytotoxicity, Immunologic
2
1997
115
0.160
Why?
Cyclooxygenase Inhibitors
1
2009
66
0.160
Why?
B-Lymphocyte Subsets
1
2009
57
0.160
Why?
Oligodeoxyribonucleotides
1
2009
136
0.160
Why?
Cell Adhesion
3
1995
261
0.160
Why?
P-Glycoprotein
2
1998
66
0.160
Why?
Anti-Inflammatory Agents, Non-Steroidal
1
2009
92
0.160
Why?
Integrin alpha1
1
2007
1
0.160
Why?
Survival Analysis
1
2010
606
0.150
Why?
Influenza A Virus, H2N2 Subtype
1
2007
3
0.150
Why?
Antigens, CD28
1
2007
35
0.150
Why?
Cell Aggregation
1
2007
27
0.150
Why?
HLA-DR1 Antigen
1
2007
4
0.150
Why?
Trans-Activators
3
1999
365
0.150
Why?
Hemagglutinins, Viral
1
2007
21
0.150
Why?
Transcription, Genetic
1
2011
812
0.140
Why?
Antibodies, Monoclonal
4
1987
711
0.140
Why?
Neutrophils
1
2009
312
0.140
Why?
Hepatitis
1
2006
14
0.140
Why?
Gene Expression Regulation, Developmental
2
1999
351
0.140
Why?
Vaccines, Subunit
1
2006
11
0.140
Why?
Viral Plaque Assay
1
2005
28
0.130
Why?
Monocytes
1
2007
308
0.130
Why?
Macrophages
1
2007
346
0.130
Why?
Dogs
1
2005
468
0.130
Why?
Bacterial Infections
1
2006
130
0.120
Why?
Hypersensitivity
1
2004
44
0.120
Why?
Transcription Factors
2
1999
687
0.120
Why?
Immunocompetence
1
2004
30
0.120
Why?
In Situ Nick-End Labeling
1
2004
94
0.120
Why?
Immunoglobulin A
1
2003
90
0.110
Why?
Ligands
3
2006
288
0.110
Why?
Virus Replication
3
1991
291
0.110
Why?
Adolescent
3
2006
4766
0.110
Why?
Bone Marrow Transplantation
2
1999
197
0.110
Why?
Lung Diseases
1
2004
228
0.110
Why?
Retroviridae
2
1998
73
0.100
Why?
Genes, T-Cell Receptor
1
2001
1
0.100
Why?
Egg Proteins
1
2001
6
0.100
Why?
Rhadinovirus
1
2001
3
0.100
Why?
Mice, Inbred Strains
4
1987
245
0.100
Why?
DNA, Recombinant
1
2001
38
0.100
Why?
Erythropoiesis
2
1998
62
0.100
Why?
Kidney
1
2005
586
0.100
Why?
Lymphocyte Cooperation
2
1998
25
0.100
Why?
Virus Latency
1
2001
14
0.100
Why?
Chimera
1
2001
35
0.100
Why?
Antigens, CD44
2
1995
15
0.100
Why?
Transfection
3
1998
859
0.100
Why?
Carrier Proteins
3
1995
426
0.090
Why?
Lymphocyte Depletion
2
1995
50
0.090
Why?
Gene Targeting
1
2000
68
0.090
Why?
Immunohistochemistry
1
2004
1064
0.090
Why?
DNA, Viral
1
2001
292
0.090
Why?
Protein-Tyrosine Kinases
2
1998
170
0.090
Why?
Antibody Specificity
1
2000
106
0.090
Why?
Lymphocyte Count
2
1996
53
0.090
Why?
Tissue Distribution
3
1997
236
0.090
Why?
Convalescence
1
1998
19
0.080
Why?
Myeloproliferative Disorders
1
1998
18
0.080
Why?
Parainfluenza Virus 1, Human
2
1995
37
0.080
Why?
Lymphoproliferative Disorders
1
1998
30
0.080
Why?
Receptors, Cytokine
1
1998
9
0.080
Why?
CD4 Lymphocyte Count
1
1998
148
0.080
Why?
Thymus Gland
4
1998
144
0.080
Why?
Mice, Inbred MRL lpr
1
1997
1
0.080
Why?
Radiation Chimera
1
1997
15
0.080
Why?
Intracellular Signaling Peptides and Proteins
1
1999
138
0.070
Why?
Hematopoietic Stem Cell Transplantation
1
1998
131
0.070
Why?
Tumor Necrosis Factor-alpha
2
1991
659
0.070
Why?
Immunoglobulin mu-Chains
1
1996
10
0.070
Why?
Germinal Center
1
1996
15
0.070
Why?
Acute Disease
1
1998
586
0.070
Why?
Crosses, Genetic
1
1996
57
0.070
Why?
Immunity
1
1997
66
0.070
Why?
Signal Transduction
3
1998
1567
0.070
Why?
Immunoglobulin Variable Region
1
1996
40
0.070
Why?
Proteins
1
1999
468
0.070
Why?
Bone Marrow
1
1997
287
0.070
Why?
Proto-Oncogene Proteins
1
1998
289
0.070
Why?
Suppressor of Cytokine Signaling Proteins
3
1999
15
0.060
Why?
STAT5 Transcription Factor
3
1999
11
0.060
Why?
Dendritic Cells
1
1996
121
0.060
Why?
Mice, Mutant Strains
3
1999
123
0.060
Why?
HLA-DR Antigens
1
1994
55
0.060
Why?
Hematopoiesis
3
1998
129
0.060
Why?
Central Nervous System
1
1995
113
0.060
Why?
Autoimmune Diseases
1
1994
80
0.060
Why?
Mice, Congenic
1
2012
7
0.050
Why?
Plasmodium berghei
1
2012
6
0.050
Why?
Lung Transplantation
1
2012
12
0.050
Why?
Cell Division
3
1998
762
0.050
Why?
Receptors, Lymphocyte Homing
3
1995
11
0.050
Why?
Transforming Growth Factor beta
1
1995
412
0.050
Why?
Fibroblasts
2
1998
534
0.050
Why?
Picornaviridae Infections
1
1991
13
0.050
Why?
Viremia
1
1991
26
0.050
Why?
Antigen-Presenting Cells
2
1995
103
0.050
Why?
Leukocyte Count
1
1991
161
0.050
Why?
Luminescent Measurements
1
2011
49
0.050
Why?
Encephalitis
1
1991
55
0.050
Why?
Antigens
1
2011
99
0.050
Why?
Antigens, CD8
2
1989
29
0.050
Why?
Enterovirus Infections
1
1989
27
0.040
Why?
Disease Outbreaks
1
2010
117
0.040
Why?
Models, Biological
2
1999
1008
0.040
Why?
Epitopes, B-Lymphocyte
1
2009
6
0.040
Why?
Malaria Vaccines
1
2009
3
0.040
Why?
Aluminum Hydroxide
1
2009
13
0.040
Why?
Clinical Trials, Phase I as Topic
1
2009
10
0.040
Why?
Antigens, CD137
1
2009
1
0.040
Why?
CpG Islands
1
2009
27
0.040
Why?
Cyclooxygenase 1
1
2009
71
0.040
Why?
Administration, Intranasal
1
2009
61
0.040
Why?
Immunodominant Epitopes
1
2009
24
0.040
Why?
Immunization, Secondary
1
2009
71
0.040
Why?
Pyrazoles
1
2009
57
0.040
Why?
Demyelinating Diseases
1
1989
77
0.040
Why?
Respiratory Function Tests
1
2009
121
0.040
Why?
Disease Susceptibility
2
1987
79
0.040
Why?
Interleukin-4
2
1999
163
0.040
Why?
Adjuvants, Immunologic
1
2009
117
0.040
Why?
Measles virus
1
2007
9
0.040
Why?
Tumor Escape
1
2007
2
0.040
Why?
Clone Cells
2
1996
186
0.040
Why?
Cancer Vaccines
1
2007
33
0.040
Why?
Macrophage Activation
1
2007
56
0.040
Why?
Isoantibodies
1
1987
57
0.040
Why?
Animals, Newborn
2
1999
488
0.040
Why?
Antiviral Agents
1
2009
175
0.040
Why?
HIV
1
2007
71
0.040
Why?
Herpesvirus 1, Human
1
2007
65
0.040
Why?
Computer Simulation
1
2009
302
0.040
Why?
Whole-Body Irradiation
1
2007
83
0.040
Why?
Predictive Value of Tests
1
2009
606
0.040
Why?
Viral Vaccines
1
2007
109
0.040
Why?
Proto-Oncogene Proteins c-bcl-2
1
2007
116
0.040
Why?
Sequence Homology, Amino Acid
1
2007
288
0.030
Why?
Intracellular Fluid
1
2006
42
0.030
Why?
Alanine Transaminase
1
2006
23
0.030
Why?
Listeria monocytogenes
1
2006
6
0.030
Why?
Dose-Response Relationship, Drug
2
1999
1117
0.030
Why?
Tetanus Toxoid
1
2006
40
0.030
Why?
Homeostasis
2
1996
177
0.030
Why?
Leukocytes
2
1995
189
0.030
Why?
Hepatocytes
1
2006
56
0.030
Why?
Dimerization
1
2006
157
0.030
Why?
Phosphorylation
2
1998
774
0.030
Why?
Bronchial Hyperreactivity
1
2004
26
0.030
Why?
DNA
2
1999
845
0.030
Why?
Severity of Illness Index
1
2009
922
0.030
Why?
Th1 Cells
1
2004
70
0.030
Why?
Th2 Cells
1
2004
94
0.030
Why?
Antigens, CD40
1
2003
54
0.030
Why?
Gene Expression Regulation
1
2009
888
0.030
Why?
Alleles
2
1987
205
0.030
Why?
Base Sequence
1
2006
1683
0.020
Why?
Neoplasms
1
2007
739
0.020
Why?
Janus Kinase 3
1
1999
4
0.020
Why?
Receptors, Interleukin-4
1
1999
4
0.020
Why?
Receptors, Interleukin-2
1
1999
30
0.020
Why?
Autoantibodies
1
2000
98
0.020
Why?
Antigens, CD3
1
1999
38
0.020
Why?
Embryo, Mammalian
1
2000
188
0.020
Why?
Interleukin-7
1
1999
10
0.020
Why?
RNA-Binding Proteins
1
2000
130
0.020
Why?
Harvey murine sarcoma virus
1
1998
1
0.020
Why?
Stem Cell Factor
1
1998
17
0.020
Why?
Genes, MDR
1
1998
10
0.020
Why?
Models, Genetic
1
1999
161
0.020
Why?
X Chromosome
1
1998
37
0.020
Why?
Thymus Neoplasms
1
1998
23
0.020
Why?
Mutagenesis
1
1999
130
0.020
Why?
In Situ Hybridization
1
1999
323
0.020
Why?
Interleukin-3
1
1998
43
0.020
Why?
Interferon Regulatory Factor-1
1
1998
4
0.020
Why?
Thrombopoietin
1
1998
7
0.020
Why?
Janus Kinase 2
1
1998
13
0.020
Why?
Colony-Stimulating Factors
1
1998
27
0.020
Why?
Transduction, Genetic
1
1998
124
0.020
Why?
CD40 Ligand
1
1998
91
0.020
Why?
Graft Survival
1
1998
148
0.020
Why?
Lymphoma
1
1998
162
0.020
Why?
Tyrosine
1
1998
132
0.020
Why?
Respiratory Tract Diseases
1
1997
45
0.020
Why?
Gene Transfer Techniques
1
1998
147
0.020
Why?
Phosphoproteins
1
1998
156
0.020
Why?
Conalbumin
1
1996
3
0.020
Why?
Indicator Dilution Techniques
1
1996
5
0.020
Why?
Genetic Vectors
1
1998
339
0.020
Why?
Polymerase Chain Reaction
1
1998
596
0.020
Why?
Interleukin-6
1
1998
339
0.020
Why?
Age Factors
1
1999
1128
0.020
Why?
Dose-Response Relationship, Immunologic
1
1995
60
0.020
Why?
Antigens, CD45
1
1995
37
0.020
Why?
Antigens, CD4
1
1995
37
0.020
Why?
Immunosuppressive Agents
1
1996
200
0.020
Why?
Blood-Brain Barrier
1
1995
108
0.020
Why?
Down-Regulation
1
1995
237
0.010
Why?
Receptors, Cell Surface
1
1995
203
0.010
Why?
Regression Analysis
1
1995
527
0.010
Why?
Picornaviridae
1
1991
1
0.010
Why?
Endothelium, Vascular
1
1995
406
0.010
Why?
RNA, Messenger
1
1998
1863
0.010
Why?
Paralysis
1
1989
54
0.010
Why?
Astrocytes
1
1991
280
0.010
Why?
Immunization, Passive
1
1987
66
0.010
Why?
Brain
1
1991
1214
0.010
Why?

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