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Jiyong Zhao

Title	Associate Professor
Institution	School of Medicine and Dentistry
Department	Biomedical Genetics
Address	University of Rochester Medical Center School of Medicine and Dentistry 601 Elmwood Ave, Box 633 Rochester NY 14642

Awards And Honors

1991	-	1992	Predoctoral Fellowship Award- Competitive Molecular Cellular and Developmental Biology Research Fellowship. Iowa State University. Ames, Iowa.
1992	-	1993	Predoctoral Fellowship Award- Fung Endowment Fellowship for Research. Iowa State University, Ames, Iowa.
1993	-	1994	Predoctoral Fellowship Award- Fung Endowment Fellowship for Research. Iowa State University, Ames, Iowa.
1997	-	1999	Postdoctoral Fellowship Award- American Cancer Society Postdoctoral Fellowship.

Selected Publications

DeRan M, Pulvino M, Zhao J. Assessing G1-to-S-phase progression after genotoxic stress. Methods Mol Biol. 2011; 782:221-30.

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Kim SW, Oleksyn DW, Rossi RM, Jordan CT, Sanz I, Chen L, Zhao J. Protein kinase C-associated kinase is required for NF-kappaB signaling and survival in diffuse large B-cell lymphoma cells. Blood. 2008 Feb 1; 111(3):1644-53.

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DeRan M, Pulvino M, Greene E, Su C, Zhao J. Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition. Mol Cell Biol. 2008 Jan; 28(1):435-47.

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Le XF, Bedrosian I, Mao W, Murray M, Lu Z, Keyomarsi K, Lee MH, Zhao J, Bast RC. Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway. Cell Cycle. 2006 Aug; 5(15):1654-61.

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Zhao J. Coordination of DNA synthesis and histone gene expression during normal cell cycle progression and after DNA damage. Cell Cycle. 2004 Jun; 3(6):695-7.

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Su C, Gao G, Schneider S, Helt C, Weiss C, O'Reilly MA, Bohmann D, Zhao J. DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway. EMBO J. 2004 Mar 10; 23(5):1133-43.

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Barbie DA, Kudlow BA, Frock R, Zhao J, Johnson BR, Dyson N, Harlow E, Kennedy BK. Nuclear reorganization of mammalian DNA synthesis prior to cell cycle exit. Mol Cell Biol. 2004 Jan; 24(2):595-607.

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Gao G, Bracken AP, Burkard K, Pasini D, Classon M, Attwooll C, Sagara M, Imai T, Helin K, Zhao J. NPAT expression is regulated by E2F and is essential for cell cycle progression. Mol Cell Biol. 2003 Apr; 23(8):2821-33.

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Zhao J, Kennedy BK, Lawrence BD, Barbie DA, Matera AG, Fletcher JA, Harlow E. NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription. Genes Dev. 2000 Sep 15; 14(18):2283-97.

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Zhao J, Dynlacht B, Imai T, Hori T, Harlow E. Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry. Genes Dev. 1998 Feb 15; 12(4):456-61.

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Wang Y, Zhao J, Clapper J, Martin LD, Du C, DeVore ER, Harkins K, Dobbs DL, Benbow RM. Mimosine differentially inhibits DNA replication and cell cycle progression in somatic cells compared to embryonic cells of Xenopus laevis. Exp Cell Res. 1995 Mar; 217(1):84-91.

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Zhao J, Benbow RM. Inhibition of DNA replication in cell-free extracts of Xenopus laevis eggs by extracts of Xenopus laevis oocytes. Dev Biol. 1994 Jul; 164(1):52-62.

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Zhao J, Benbow RM. An inhibitor of DNA topoisomerase I from Xenopus laevis ovaries. Biochemistry. 1993 Oct 12; 32(40):10622-8.

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Benbow RM, Zhao J, Larson DD. On the nature of origins of DNA replication in eukaryotes. Bioessays. 1992 Oct; 14(10):661-70.

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Zhao JY, Ford CF, Glatz CE, Rougvie MA, Gendel SM. Polyelectrolyte precipitation of beta-galactosidase fusions containing poly-aspartic acid tails. J Biotechnol. 1990 Jun; 14(3-4):273-83.

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Zhu XM, Zhao JY, Luo QX, Wang ZT. [Analysis of degradative plasmids by pyrolysis gas liquid chromatography]. Wei Sheng Wu Xue Bao. 1988 Mar; 28(1):62-7.

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