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Marc Lande

TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentPediatrics
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 777
Rochester NY 14642
 
 Awards And Honors
1981     Phi Beta Kappa ( University of Virginia)
1982     Raven Society (University of Virginia)
1988     Gilbert Forbes Resident Research Award
1990     Commissioned Officer Service Award
1993     Henry Christian Memorial Award  | American Federation For Clinical Research Foundation
1996     Rose Award (OHSU)
1997     Rose Award (OHSU)
2006     American College of Cardiology Foundation/Pfizer Visiting Professor in Cardiovascular Medicine Award  | (Visiting Professor - Ron Portman, MD)
2008     Society for Pediatric Research Election (SPR)
 
 Overview
Hypertension is estimated to affect 50 million Americans and is a leading cause of cardiovascular disease, stroke, and kidney disease. Although such morbid events as stroke and myocardial infarction are uncommon in childhood, it is clear that the origins of cardiovascular disease and essential hypertension begin early in life and that hypertensive end-organ damage may occur at a young age. Understanding the early time course in how hypertension affects the susceptible organs is important, so that strategies to prevent the development of target-organ damage can be developed.

Dr. Lande is studying vascular changes as markers of early hypertensive target-organ damage in children. In addition, he is studying the neurocognitive effects of hypertension in children and determining any potential benefit of antihypertensive therapy on cognition. He is also focusing on the psychological correlates of hypertension in children.

 
 Selected Publications
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  1. Lande MB, Kupferman JC, Hooper SR, Pavlakis SG, Batisky DL, Adams HR. Blood pressure and school performance. Psychosom Med. 2014 Feb; 76(2):163-6.
    View in: PubMed
  2. Lande MB, Kupferman JC. Pediatric hypertension: the year in review. Clin Pediatr (Phila). 2014 Apr; 53(4):315-9.
    View in: PubMed
  3. Lande MB, Adams HR, Kupferman JC, Hooper SR, Szilagyi PG, Batisky DL. A multicenter study of neurocognition in children with hypertension: Methods, challenges, and solutions. J Am Soc Hypertens. 2013 Sep-Oct; 7(5):353-62.
    View in: PubMed
  4. Kupferman JC, Lande MB, Adams HR, Pavlakis SG. Primary hypertension and neurocognitive and executive functioning in school-age children. Pediatr Nephrol. 2013 Mar; 28(3):401-8.
    View in: PubMed
  5. Lande MB, Kupferman JC, Adams HR. Neurocognitive alterations in hypertensive children and adolescents. J Clin Hypertens (Greenwich). 2012 Jun; 14(6):353-9.
    View in: PubMed
  6. Hooper SR, Gerson AC, Butler RW, Gipson DS, Mendley SR, Lande MB, Shinnar S, Wentz A, Matheson M, Cox C, Furth SL, Warady BA. Neurocognitive functioning of children and adolescents with mild-to-moderate chronic kidney disease. Clin J Am Soc Nephrol. 2011 Aug; 6(8):1824-30.
    View in: PubMed
  7. Lande MB, Gerson AC, Hooper SR, Cox C, Matheson M, Mendley SR, Gipson DS, Wong C, Warady BA, Furth SL, Flynn JT. Casual blood pressure and neurocognitive function in children with chronic kidney disease: a report of the children with chronic kidney disease cohort study. Clin J Am Soc Nephrol. 2011 Aug; 6(8):1831-7.
    View in: PubMed
  8. Adams HR, Szilagyi PG, Gebhardt L, Lande MB. Learning and attention problems among children with pediatric primary hypertension. Pediatrics. 2010 Dec; 126(6):e1425-9.
    View in: PubMed
  9. Jo CO, Lande MB, Meagher CC, Wang H, Vermilion RP. A simple method of measuring thoracic aortic pulse wave velocity in children: methods and normal values. J Am Soc Echocardiogr. 2010 Jul; 23(7):735-40.
    View in: PubMed
  10. Lande MB, Adams H, Falkner B, Waldstein SR, Schwartz GJ, Szilagyi PG, Wang H, Palumbo D. Parental assessment of executive function and internalizing and externalizing behavior in primary hypertension after anti-hypertensive therapy. J Pediatr. 2010 Jul; 157(1):114-9.
    View in: PubMed
  11. Gerson AC, Wentz A, Abraham AG, Mendley SR, Hooper SR, Butler RW, Gipson DS, Lande MB, Shinnar S, Moxey-Mims MM, Warady BA, Furth SL. Health-related quality of life of children with mild to moderate chronic kidney disease. Pediatrics. 2010 Feb; 125(2):e349-57.
    View in: PubMed
  12. Lande MB, Pearson TA, Vermilion RP, Auinger P, Fernandez ID. Elevated blood pressure, race/ethnicity, and C-reactive protein levels in children and adolescents. Pediatrics. 2008 Dec; 122(6):1252-7.
    View in: PubMed
  13. Lande MB, Adams H, Falkner B, Waldstein SR, Schwartz GJ, Szilagyi PG, Wang H, Palumbo D. Parental assessments of internalizing and externalizing behavior and executive function in children with primary hypertension. J Pediatr. 2009 Feb; 154(2):207-12.
    View in: PubMed
  14. Lande MB, Meagher CC, Fisher SG, Belani P, Wang H, Rashid M. Left ventricular mass index in children with white coat hypertension. J Pediatr. 2008 Jul; 153(1):50-4.
    View in: PubMed
  15. Lande MB, Flynn JT. Treatment of hypertension in children and adolescents. Pediatr Nephrol. 2009 Oct; 24(10):1939-49.
    View in: PubMed
  16. Nicoletta JA, Lande MB. Medical evaluation and treatment of urolithiasis. Pediatr Clin North Am. 2006 Jun; 53(3):479-91, vii.
    View in: PubMed
  17. Lande MB, Carson NL, Roy J, Meagher CC. Effects of childhood primary hypertension on carotid intima media thickness: a matched controlled study. Hypertension. 2006 Jul; 48(1):40-4.
    View in: PubMed
  18. Gerson AC, Butler R, Moxey-Mims M, Wentz A, Shinnar S, Lande MB, Mendley SR, Warady BA, Furth SL, Hooper SR. Neurocognitive outcomes in children with chronic kidney disease: Current findings and contemporary endeavors. Ment Retard Dev Disabil Res Rev. 2006; 12(3):208-15.
    View in: PubMed
  19. Lande MB, Varade W, Erkan E, Niederbracht Y, Schwartz GJ. Role of urinary supersaturation in the evaluation of children with urolithiasis. Pediatr Nephrol. 2005 Apr; 20(4):491-4.
    View in: PubMed
  20. Schwaderer AL, Arend L, Lande MB. Granulomatous interstitial nephritis associated with bone marrow transplantation. Pediatr Nephrol. 2005 Apr; 20(4):539-42.
    View in: PubMed
  21. Lande MB, Kaczorowski JM, Auinger P, Schwartz GJ, Weitzman M. Elevated blood pressure and decreased cognitive function among school-age children and adolescents in the United States. J Pediatr. 2003 Dec; 143(6):720-4.
    View in: PubMed
  22. Chan JC, Mahan JD, Trachtman H, Scheinman J, Flynn JT, Alon US, Lande MB, Weiss RA, Norkus EP. Vitamin E therapy in IgA nephropathy: a double-blind, placebo-controlled study. Pediatr Nephrol. 2003 Oct; 18(10):1015-9.
    View in: PubMed
  23. Lande MB, Gullion C, Hogg RJ, Gauthier B, Shah B, Leonard MB, Bonilla-Felix M, Nash M, Roy S, Strife CF, Arbus G. Long versus standard initial steroid therapy for children with the nephrotic syndromeA report from the Southwest Pediatric Nephrology Study Group. Pediatr Nephrol. 2003 Apr; 18(4):342-6.
    View in: PubMed
  24. Soliday E, Lande MB. Family structure and the course of steroid-sensitive nephrotic syndrome. Pediatr Nephrol. 2002 Jan; 17(1):41-4.
    View in: PubMed
  25. Soliday E, Moore KJ, Lande MB. Daily reports and pooled time series analysis: pediatric psychology applications. J Pediatr Psychol. 2002 Jan-Feb; 27(1):67-76.
    View in: PubMed
  26. Lande MB, Thomas GA, Houghton DC. Membranous nephropathy associated with chronic immune thrombocytopenic purpura in childhood. Am J Kidney Dis. 2001 May; 37(5):E40.
    View in: PubMed
  27. Soliday E, Kool E, Lande MB. Family environment, child behavior, and medical indicators in children with kidney disease. Child Psychiatry Hum Dev. 2001; 31(4):279-95.
    View in: PubMed
  28. Brunner LJ, Pai KS, Munar MY, Lande MB, Olyaei AJ, Mowry JA. Effect of grapefruit juice on cyclosporin A pharmacokinetics in pediatric renal transplant patients. Pediatr Transplant. 2000 Nov; 4(4):313-21.
    View in: PubMed
  29. Lande MB, Leonard MB. Variability among pediatric nephrologists in the initial therapy of nephrotic syndrome. Pediatr Nephrol. 2000 Aug; 14(8-9):766-9.
    View in: PubMed
  30. Goldstein SL, Somers MJ, Lande MB, Brewer ED, Jabs KL. Acyclovir prophylaxis of varicella in children with renal disease receiving steroids. Pediatr Nephrol. 2000 Apr; 14(4):305-8.
    View in: PubMed
  31. Soliday E, Kool E, Lande MB. Psychosocial adjustment in children with kidney disease. J Pediatr Psychol. 2000 Mar; 25(2):93-103.
    View in: PubMed
  32. Soliday E, Grey S, Lande MB. Behavioral effects of corticosteroids in steroid-sensitive nephrotic syndrome. Pediatrics. 1999 Oct; 104(4):e51.
    View in: PubMed
  33. Lashley DB, Barry JM, Demattos AM, Lande MB, Mowry JA. Kidney transplantation in children: a single center experience. J Urol. 1999 Jun; 161(6):1920-5.
    View in: PubMed
  34. Lande MB, Mowry JA, Houghton DC, White CR, Borzy MS. Immune complex disease associated with Epstein-Barr virus infectious mononucleosis. Pediatr Nephrol. 1998 Oct; 12(8):651-3.
    View in: PubMed
  35. Lande MB, Jo I, Zeidel ML, Somers M, Harris HW. Phosphorylation of aquaporin-2 does not alter the membrane water permeability of rat papillary water channel-containing vesicles. J Biol Chem. 1996 Mar 8; 271(10):5552-7.
    View in: PubMed
  36. D'Angio CT, Froehlke RG, Plank GA, Meehan DJ, Aguilar CM, Lande MB, Hugar L. Long-term outcome of Haemophilus influenzae meningitis in Navajo Indian children. Arch Pediatr Adolesc Med. 1995 Sep; 149(9):1001-8.
    View in: PubMed
  37. Lande MB, Donovan JM, Zeidel ML. The relationship between membrane fluidity and permeabilities to water, solutes, ammonia, and protons. J Gen Physiol. 1995 Jul; 106(1):67-84.
    View in: PubMed
  38. Agre P, Smith BL, Baumgarten R, Preston GM, Pressman E, Wilson P, Illum N, Anstee DJ, Lande MB, Zeidel ML. Human red cell Aquaporin CHIP. II. Expression during normal fetal development and in a novel form of congenital dyserythropoietic anemia. J Clin Invest. 1994 Sep; 94(3):1050-8.
    View in: PubMed
  39. Lande MB, Priver NA, Zeidel ML. Determinants of apical membrane permeabilities of barrier epithelia. Am J Physiol. 1994 Aug; 267(2 Pt 1):C367-74.
    View in: PubMed
  40. Lande MB, Gleeson JG, Sundel RP. Kawasaki disease and acute renal failure. Pediatr Nephrol. 1993 Oct; 7(5):593.
    View in: PubMed
  41. Lande MB, Kim MS, Bartlett C, Guay-Woodford LM. Reversible Fanconi syndrome associated with valproate therapy. J Pediatr. 1993 Aug; 123(2):320-2.
    View in: PubMed
  42. Lande MB, Richardson AC, White KC. The role of syphilis serology in the evaluation of suspected sexual abuse. Pediatr Infect Dis J. 1992 Feb; 11(2):125-7.
    View in: PubMed

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