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Marshall Lichtman

TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentMedicine
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box MED
Rochester NY 14642
Other Positions
TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentBiochemistry and Biophysics

 
 Awards And Honors
1957     James A. Gibson Anatomical Sciences Honor Society  | University of Buffalo School of Medicine
1959     James A. Gibson Anatomical Society Prize  | University of Buffalo School of Medicine
1960     Alpha Omega Alpha Medical Honor Society  | University of Buffalo School of Medicine
1960     Wayne-Atwell Medicine Award and Prize  | University of Buffalo School of Medicine
1960     Morris-Stein Neuroscience Award and Prize  | University of Buffalo School of Medicine
1960     Buffalo Surgical Society Prize  | University of Buffalo School of Medicine
1960     Buffalo Obstetrical and Gynecological Society Prize  | University of Buffalo School of Medicine
1960     Mosby Publishing Company Scholarship Award  | Mosby Publishing Company
1969 - 1974Scholar of the Leukemia Society of America  | Leukemia Society of America
1973     Elected to the American Society for Clinical Investigation  | American Society for Clinical Investigation
1974     Elected to the Association of American Physicians  | Association of American Physicians
1989     President, American Society of Hematology  | American Society of Hematology
1994     Master, American College of Physicians  | American College of Physicians
2001     Distinguished Alumnus Award 2001  | University of Buffalo School of Medicine and Biomedical Sciences
2006     Rochester Academy of Medicine, Certificate of Merit  | Rochester Academy of Medicine
2007     Marshall A. Lichtman Annual Research Symposium  | The Leukemia & Lymphoma Society
2008     Marshall A. Lichtman Specialized Center of Research Grant  | The Leukemia & Lymphoma Society
 
 Overview
Marshall A. Lichtman received the Bachelor of Arts degree from Cornell University and the M.D. degree from the University of Buffalo School of Medicine in 1960.

Dr. Lichtman was a resident in medicine at the University of Rochester Medical Center and Strong Memorial Hospital from 1960-1963. After two years in the Public Health Service (1963-1965), he returned to Rochester to be Chief Resident in Medicine (1965-1966). Thereafter, he was awarded a Special Postdoctoral Research Fellowship from the National Institutes of Health from 1967 to 1969 to conduct studies on the biochemistry and physiology of blood cells and their abnormalities in leukemia. Dr. Lichtman was named a Scholar of the Leukemia Society of America in 1969. In 1968 he was appointed Assistant Professor of Medicine and in 1970, Assistant Professor of Biophysics. He was appointed Professor of Medicine and of Biophysics in 1974. In 1975 he was named Chief of the Hematology Unit. From 1979 to 1980, he was Associate Dean for Academic Affairs and Research, from 1980 to 1988, he was Senior Associate Dean for Academic Affairs and Research, and from 1988 to 1989, he was Academic Dean, in addition to his role as a teacher, scientist, and hematologist.

Dr. Lichtman served as the sixth Dean of the University of Rochester School of Medicine and Dentistry for six years from January 1, 1990 to December 31, 1995 and during that time supervised the School's thirty-three academic departments, divisions, and Centers, fifteen hundred medical, graduate, and post-doctoral students, nine hundred full-time faculty, and diverse educational, research, and patient care programs. From 1996 to 2007, he was the Executive Vice President for Research and Medical Affairs of The Leukemia and Lymphoma Society, retaining his appointment as Professor of Medicine and of Biochemistry and Biophysics at the University of Rochester.

Dr. Lichtman has served on the editorial board of nine scientific journals and as the editor-in-chief of Blood Cells, Molecules, and Diseases. He has been the editor of three monographs and five textbooks of hematology, one of which is in its eighth edition, and has authored over 300 scientific articles, reviews, editorials, and book chapters on the physiology, biochemistry, and disorders of blood cells. From 1967 to 1995, his research was sponsored by the National Institutes of Health, the American Cancer Society, the Leukemia Society of America, the Department of Energy, the U.S. Army Biomedical Research Program, and several foundations. He has been elected to the American Society for Clinical Investigation and the Association of American Physicians, and is a member of several scientific societies including the American Physiological Society and the American Society of Cell Biology. He is a Master of The American College of Physicians. He has received the Distinguished Alumnus Award of the University of Buffalo School Of Medicine and the Certificate of Merit of the Rochester Academy of Medicine. He is listed in Marquis Who's Who in America, in the World, in Frontiers of Science and Technology, and in Medicine and Healthcare.

Dr. Lichtman has been a visiting professor at over forty Medical Centers in the United States and Canada, has served on several national advisory groups, including the Hematology Study Section of the National Institutes of Health. He was Chair of the peer review group of the Division of Biological and Medical Research of the U.S. Navy, and Chair of the Scientific Council of the American Red Cross, Holland Research Laboratories. He has been president of the American Society of Hematology and has been Chair of the Society's Advisory Board. Dr. Lichtman has served on the Council for Graduate Medical Education of the State of New York and the Board of Trustees of the State University of New York, the later two positions, Gubernatorial appointments. He was a member of the Board of Governors of the American Red Cross.

 
 Selected Publications
  • Lichtman MA. A historical perspective on the development of the cytarabine (7days) and daunorubicin (3days) treatment regimen for acute myelogenous leukemia: 2013 the 40th anniversary of 7+3. Blood Cells Mol Dis. 2013 Feb; 50(2):119-30.
    View in: PubMed
  • Lichtman MA. Call it cancer: letting the histopathology determine the diagnosis. Oncologist. 2012; 17(5):586.
    View in: PubMed
  • Lichtman MA. Obesity and the risk of chronic myelogenous leukemia: is this another example of the neoplastic effects of increased body fat? Leukemia. 2012 Jan; 26(1):183-4.
    View in: PubMed
  • Segel GB, Simon W, Lichtman MA. Should we still be focused on red cell hemoglobin F as the principal explanation for the salutary effect of hydroxyurea in sickle cell disease? Pediatr Blood Cancer. 2011 Jul 15; 57(1):8-9.
    View in: PubMed
  • Segel GB, Halterman MW, Lichtman MA. The paradox of the neutrophil's role in tissue injury. J Leukoc Biol. 2011 Mar; 89(3):359-72.
    View in: PubMed
  • Lichtman MA. Monoclonal gammopathy: do we know its significance? Blood Cells Mol Dis. 2010 Dec 15; 45(4):267-8.
    View in: PubMed
  • Lichtman MA. Obesity and the risk for a hematological malignancy: leukemia, lymphoma, or myeloma. Oncologist. 2010; 15(10):1083-101.
    View in: PubMed
  • Lichtman MA. Establishment of the Ernest Beutler Memorial Lecture. Best Pract Res Clin Haematol. 2009 Dec; 22(4):479-81.
    View in: PubMed
  • Lichtman MA. Is there an entity of chemically induced BCR-ABL-positive chronic myelogenous leukemia? Oncologist. 2008 Jun; 13(6):645-54.
    View in: PubMed
  • Lichtman MA. Battling the hematological malignancies: the 200 years' war. Oncologist. 2008 Feb; 13(2):126-38.
    View in: PubMed
  • Lichtman MA. Chronic megakaryocytic leukemia, misnamed chronic idiopathic myelofibrosis, has neoplastic not hyperplastic megakaryocytopoiesis. Blood. 2007 Oct 15; 110(8):3085-6.
    View in: PubMed
  • Lichtman MA. Cigarette smoking, cytogenetic abnormalities, and acute myelogenous leukemia. Leukemia. 2007 Jun; 21(6):1137-40.
    View in: PubMed
  • Simon W, Segel GB, Lichtman MA. Early allogeneic stem cell transplantation for chronic myelogenous leukemia in the imatinib era: a preliminary assessment. Blood Cells Mol Dis. 2006 Sep-Oct; 37(2):116-24; discussion 125-7.
    View in: PubMed
  • Lichtman MA, Segel GB. Uncommon phenotypes of acute myelogenous leukemia: basophilic, mast cell, eosinophilic, and myeloid dendritic cell subtypes: a review. Blood Cells Mol Dis. 2005 Nov-Dec; 35(3):370-83.
    View in: PubMed
  • Lichtman MA. Is it chronic idiopathic myelofibrosis, myelofibrosis with myeloid metaplasia, chronic megakaryocytic-granulocytic myelosis, or chronic megakaryocytic leukemia? Further thoughts on the nosology of the clonal myeloid disorders. Leukemia. 2005 Jul; 19(7):1139-41.
    View in: PubMed
  • Lichtman MA, Hunter MD, Liders GJ. Intellectual property--the dispute between research institutions and voluntary health agencies. Nat Biotechnol. 2004 Apr; 22(4):385-6.
    View in: PubMed
  • Lichtman MA, Rowe JM. The relationship of patient age to the pathobiology of the clonal myeloid diseases. Semin Oncol. 2004 Apr; 31(2):185-97.
    View in: PubMed
  • Segel GB, Lichtman MA. Familial (inherited) leukemia, lymphoma, and myeloma: an overview. Blood Cells Mol Dis. 2004 Jan-Feb; 32(1):246-61.
    View in: PubMed
  • Segel GB, Woodlock TJ, Xu J, Li L, Felgar RE, Ryan DH, Lichtman MA, Wang N. Early gene activation in chronic leukemic B lymphocytes induced toward a plasma cell phenotype. Blood Cells Mol Dis. 2003 May-Jun; 30(3):277-87.
    View in: PubMed
  • Lichtman MA. Language and the clonal myeloid diseases. Blood. 2002 Jan 15; 99(2):725-6.
    View in: PubMed
  • Lichtman MA, Oakes D. The productivity and impact of the Leukemia & Lymphoma Society Scholar Program: the apparent positive effect of peer review. Blood Cells Mol Dis. 2001 Nov-Dec; 27(6):1020-7.
    View in: PubMed
  • Lichtman MA. The stem cell in the pathogenesis and treatment of myelogenous leukemia: a perspective. Leukemia. 2001 Oct; 15(10):1489-94.
    View in: PubMed
  • Cech TR, Egan LW, Doyle C, Gallin E, Lichtman MA, Queenan CJ, Sung N. The biomedical research bottleneck. Science. 2001 Jul 27; 293(5530):573.
    View in: PubMed
  • Lichtman MA. Differentiation versus maturation of neoplastic hematopoietic cells: an important distinction. Blood Cells Mol Dis. 2001 May-Jun; 27(3):649-52.
    View in: PubMed
  • Lichtman MA. Introduction of Ernest Beutler, MD. Leukemia. 2001 Apr; 15(4):656-7.
    View in: PubMed
  • Lichtman MA. Hope for leukemia. Health News. 2001 Jan; 7(1):3.
    View in: PubMed
  • Lichtman MA. Myelodysplasia or myeloneoplasia: thoughts on the nosology of clonal myeloid diseases. Blood Cells Mol Dis. 2000 Dec; 26(6):572-81.
    View in: PubMed
  • Lichtman MA. Interrupting the inhibiton of normal hematopoiesis in myelogenous leukemia: a hypothetical approach to therapy. Stem Cells. 2000; 18(5):304-6.
    View in: PubMed
  • Woodlock TJ, Chen X, Young DA, Bethlendy G, Lichtman MA, Segel GB. Association of HSP60-like proteins with the L-system amino acid transporter. Arch Biochem Biophys. 1997 Feb 1; 338(1):50-6.
    View in: PubMed
  • Li WZ, Lin P, Frydman J, Boal TR, Cardillo TS, Richard LM, Toth D, Lichtman MA, Hartl FU, Sherman F, et al. Tcp20, a subunit of the eukaryotic TRiC chaperonin from humans and yeast. J Biol Chem. 1994 Jul 15; 269(28):18616-22.
    View in: PubMed
  • Woodlock TJ, Young DA, Boal TR, Lichtman MA, Segel GB. Phorbol ester-induced membrane proteins in chronic leukemic B-lymphocytes. Candidate proteins for the L-system amino acid transporter. J Biol Chem. 1993 Jul 25; 268(21):16020-7.
    View in: PubMed
  • Harmon CS, Lichtman M, Parker R, Hallas G. Making new employees an integral part of the team. Contemp Longterm Care. 1992 Aug; 15(8):24, 70.
    View in: PubMed
  • Segel GB, Boal TR, Cardillo TS, Murant FG, Lichtman MA, Sherman F. Isolation of a gene encoding a chaperonin-like protein by complementation of yeast amino acid transport mutants with human cDNA. Proc Natl Acad Sci U S A. 1992 Jul 1; 89(13):6060-4.
    View in: PubMed
  • Sham RL, Packman CH, Abboud CN, Lichtman MA. Signal transduction and the regulation of actin conformation during myeloid maturation: studies in HL60 cells. Blood. 1991 Jan 15; 77(2):363-70.
    View in: PubMed
  • Liang SL, Woodlock TJ, Whitin JC, Lichtman MA, Segel GB. Signal transduction in N-formyl-methionyl-leucyl-phenylalanine and concanavalin A stimulated human neutrophils: superoxide production without a rise in intracellular free calcium. J Cell Physiol. 1990 Nov; 145(2):295-302.
    View in: PubMed
  • Packman CH, Lichtman MA. Activation of neutrophils: measurement of actin conformational changes by flow cytometry. Blood Cells. 1990; 16(1):193-205; discussion 205-7.
    View in: PubMed
  • Sham RL, Packman CH, Abboud CN, Lichtman MA. Control of actin conformation in AML myeloblasts: the effects of bryostatin and TPA. Leuk Res. 1990; 14(10):863-8.
    View in: PubMed
  • Costa-Casnellie MR, Cragoe EJ, Segel GB, Lichtman MA. Activation of the Na+/H+ exchanger by phorbol ester and osmotic shock is dependent on the degree of neutrophilic maturation. J Cell Physiol. 1989 Nov; 141(2):294-300.
    View in: PubMed
  • Segel GB, Woodlock TJ, Murant FG, Lichtman MA. Photoinhibition of 2-amino-2-carboxybicyclo[2,2,1]heptane transport by O-diazoacetyl-L-serine. An initial step in identifying the L-system amino acid transporter. J Biol Chem. 1989 Oct 5; 264(28):16399-402.
    View in: PubMed
  • Woodlock TJ, Segel GB, Lichtman MA. Diacylglycerol and calcium induce rapid enhancement of A-system amino acid transport by independent mechanisms in human T-lymphocytes. J Cell Physiol. 1989 Oct; 141(1):33-9.
    View in: PubMed
  • Liesveld JL, Abboud CN, Duerst RE, Ryan DH, Brennan JK, Lichtman MA. Characterization of human marrow stromal cells: role in progenitor cell binding and granulopoiesis. Blood. 1989 May 15; 73(7):1794-800.
    View in: PubMed
  • Phatak PD, Packman CH, Lichtman MA. Protein kinase C modulates actin conformation in human T lymphocytes. J Immunol. 1988 Nov 1; 141(9):2929-34.
    View in: PubMed
  • Simon W, Segel GB, Lichtman MA. Upper and lower time limits in the decision to recommend marrow transplantation for patients with chronic myelogenous leukaemia. Br J Haematol. 1988 Sep; 70(1):31-6.
    View in: PubMed
  • Costa-Casnellie MR, Segel GB, Lichtman MA. The Na+/H+ exchanger in immature and mature granulocytic HL-60 cells. Property changes induced by intracellular acidification and cell maturation. J Biol Chem. 1988 Aug 25; 263(24):11851-5.
    View in: PubMed
  • Segel GB, Woodlock TJ, Lichtman MA. Trans-stimulation of L-system amino acid transport in normal and chronic leukemic human lymphocytes: phorbol ester restores function in CLL. J Cell Physiol. 1988 Mar; 134(3):503-8.
    View in: PubMed
  • Woodlock TJ, Segel GB, Lichtman MA. Phorbol ester restores L-system amino acid transport of B lymphocytes in chronic lymphocytic leukemia. J Clin Invest. 1988 Jan; 81(1):32-8.
    View in: PubMed
  • Lichtman MA, Heal J, Rowe JM. Hyperleukocytic leukaemia: rheological and clinical features and management. Baillieres Clin Haematol. 1987 Sep; 1(3):725-46.
    View in: PubMed
  • Wallace PJ, Packman CH, Wersto RP, Lichtman MA. The effects of sulfhydryl inhibitors and cytochalasin on the cytoplasmic and cytoskeletal actin of human neutrophils. J Cell Physiol. 1987 Aug; 132(2):325-30.
    View in: PubMed
  • Costa-Casnellie MR, Segel GB, Cragoe EJ, Lichtman MA. Characterization of the Na+/H+ exchanger during maturation of HL-60 cells induced by dimethyl sulfoxide. J Biol Chem. 1987 Jul 5; 262(19):9093-7.
    View in: PubMed
  • Liesveld JL, Rowe JM, Lichtman MA. Variability of the erythropoietic response in autoimmune hemolytic anemia: analysis of 109 cases. Blood. 1987 Mar; 69(3):820-6.
    View in: PubMed
  • Wallace PJ, Packman CH, Lichtman MA. Maturation-associated changes in the peripheral cytoplasm of human neutrophils: a review. Exp Hematol. 1987 Jan; 15(1):34-45.
    View in: PubMed
  • Costa-Casnellie MR, Segel GB, Lichtman MA. Signal transduction in human monocytes: relationship between superoxide production and the level of kinase C in the membrane. J Cell Physiol. 1986 Dec; 129(3):336-42.
    View in: PubMed
  • Segel GB, Simon W, Lichtman MA. Variables influencing the timing of marrow transplantation in patients with chronic myelogenous leukemia. Blood. 1986 Nov; 68(5):1055-64.
    View in: PubMed
  • Scully SP, Segel GB, Lichtman MA. Relationship of superoxide production to cytoplasmic free calcium in human monocytes. J Clin Invest. 1986 Apr; 77(4):1349-56.
    View in: PubMed
  • Lichtman MA, Santillo P. Red cell egress from the marrow: ? vis-à-tergo. Blood Cells. 1986; 12(1):11-23.
    View in: PubMed
  • Costa-Casnellie MR, Segel GB, Lichtman MA. Concanavalin A and phorbol ester cause opposite subcellular redistribution of protein kinase C. Biochem Biophys Res Commun. 1985 Dec 31; 133(3):1139-44.
    View in: PubMed
  • Segel GB, Tometsko AM, Lichtman MA. Y+- and L-system amino acid transport in normal and chronic lymphocytic leukemia lymphocytes: photoinhibition by fluoronitrophenylazide. Arch Biochem Biophys. 1985 Nov 1; 242(2):347-54.
    View in: PubMed
  • Slovick FT, Abboud CN, Brennan JK, Lichtman MA. Modulation of in vitro eosinophil progenitors by hydrocortisone: role of accessory cells and interleukins. Blood. 1985 Nov; 66(5):1072-9.
    View in: PubMed
  • Segel GB, Ryan DH, Lichtman MA. Ecto-nucleotide triphosphatase activity of human lymphocytes: studies of normal and CLL lymphocytes. J Cell Physiol. 1985 Sep; 124(3):424-32.
    View in: PubMed
  • Wallace PJ, Wersto RP, Packman CH, Lichtman MA. Chemotactic peptide-induced changes in neutrophil actin conformation. J Cell Biol. 1984 Sep; 99(3):1060-5.
    View in: PubMed
  • Scully SP, Segel GB, Lichtman MA. Calcium exchange and ionized cytoplasmic calcium in resting and activated human monocytes. J Clin Invest. 1984 Aug; 74(2):589-99.
    View in: PubMed
  • Segel GB, Simon W, Lichtman MA. Multicomponent analysis of amino acid transport in human lymphocytes. Diminished L-system transport in chronic leukemic B lymphocytes. J Clin Invest. 1984 Jul; 74(1):17-24.
    View in: PubMed
  • Slovick FT, Abboud CN, Brennan JK, Lichtman MA. Survival of granulocytic progenitors in the nonadherent and adherent compartments of human long-term marrow cultures. Exp Hematol. 1984 Jun; 12(5):327-38.
    View in: PubMed
  • Rowe JM, Lichtman MA. Hyperleukocytosis and leukostasis: common features of childhood chronic myelogenous leukemia. Blood. 1984 May; 63(5):1230-4.
    View in: PubMed
  • Lichtman MA. The relationship of stromal cells to hemopoietic cells in marrow. Kroc Found Ser. 1984; 18:3-29.
    View in: PubMed
  • Lichtman MA. The relationship of excessive white cell accumulation to vascular insufficiency in patients with leukemia. Kroc Found Ser. 1984; 16:295-306.
    View in: PubMed
  • Segel GB, Simon W, Lichtman MA. A multicomponent analysis of amino acid transport systems in human lymphocytes. 1. Kinetic parameters of the A and L systems and pathways of uptake of naturally occurring amino acids in blood lymphocytes. J Cell Physiol. 1983 Sep; 116(3):372-8.
    View in: PubMed
  • Doolittle RL, Packman CH, Lichtman MA. Amino-sugars enhance recognition and phagocytosis of particles by human neutrophils. Blood. 1983 Sep; 62(3):697-701.
    View in: PubMed
  • Lichtman AH, Segel GB, Lichtman MA. The role of calcium in lymphocyte proliferation. (An interpretive review). Blood. 1983 Mar; 61(3):413-22.
    View in: PubMed
  • Lichtman MA. Hemopoietic stem cell disorders. Am J Med Technol. 1983 Feb; 49(2):97-102.
    View in: PubMed
  • Santillo PA, Lichtman MA. Holey red cells: a brief note. Blood Cells. 1983; 9(1):169-72.
    View in: PubMed
  • Barlow GH, Brennan JK, Abboud CN, Francis CW, Lichtman AH, Lichtman MA. Secretion of plasminogen activator by the human macrophage-like cell line, GCT: separation from colony-stimulating and erythropoiesis-enhancing activities. Br J Haematol. 1982 Dec; 52(4):645-55.
    View in: PubMed
  • Scully SP, Segel GB, Lichtman MA. Plasma membrane vesicles prepared from unadhered monocytes: characterization of calcium transport and the calcium ATPase. Cell Calcium. 1982 Dec; 3(6):515-30.
    View in: PubMed
  • Segel GB, Lichtman MA. Decreased L-system for amino acid transport in chronic lymphocytic leukemic lymphocytes. J Biol Chem. 1982 Aug 25; 257(16):9255-7.
    View in: PubMed
  • Lichtman MA, Rowe JM. Hyperleukocytic leukemias: rheological, clinical, and therapeutic considerations. Blood. 1982 Aug; 60(2):279-83.
    View in: PubMed
  • Lichtman AH, Segel GB, Lichtman MA. Effects of trifluoperazine and mitogenic lectins on calcium ATPase activity and calcium transport by human lymphocyte plasma membrane vesicles. J Cell Physiol. 1982 May; 111(2):213-7.
    View in: PubMed
  • Weiner AS, Lichtman M. The nursing home as a teaching and research center. J Long Term Care Adm. 1982; 10(3):2-8.
    View in: PubMed
  • Abboud CN, Brennan JK, Barlow GH, Lichtman MA. Hydrophobic adsorption chromatography of colony-stimulating activities and erythroid-enhancing activity from the human monocyte-like cell line, GCT. Blood. 1981 Dec; 58(6):1148-54.
    View in: PubMed
  • Brennan JK, Abboud CN, DiPersio JF, Barlow GH, Lichtman MA. Autostimulation of growth by human myelogenous leukemia cells (HL-60). Blood. 1981 Oct; 58(4):803-12.
    View in: PubMed
  • Lawrence WD, Packman CH, Rowe JM, Lichtman MA. Attachment of particle-bound IgG and complement to human neutrophils. Blood. 1981 Oct; 58(4):772-81.
    View in: PubMed
  • Segel GB, Simon W, Lichtman AH, Lichtman MA. The activation of lymphocyte plasma membrane (Na,K)-ATPase by EGTA is explained better by zinc than calcium chelation. J Biol Chem. 1981 Jul 10; 256(13):6629-32.
    View in: PubMed
  • Lichtman AH, Segel GB, Lichtman MA. Calcium transport and calcium-ATPase activity in human lymphocyte plasma membrane vesicles. J Biol Chem. 1981 Jun 25; 256(12):6148-54.
    View in: PubMed
  • Moosavi H, Lichtman MA, Donnelly JA, Churukian CJ. Plastic-embedded human marrow biopsy specimens: improved histochemical methods. Arch Pathol Lab Med. 1981 May; 105(5):269-73.
    View in: PubMed
  • Quastel MR, Segel GB, Lichtman MA. The effect of calcium chelation on lymphocyte monovalent cation permeability, transport and concentration. J Cell Physiol. 1981 May; 107(2):165-70.
    View in: PubMed
  • Segel GB, Cokelet GR, Lichtman MA. The measurement of lymphocyte volume: importance of reference particle deformability and counting solution tonicity. Blood. 1981 May; 57(5):894-9.
    View in: PubMed
  • Lichtman MA. The ultrastructure of the hemopoietic environment of the marrow: a review. Exp Hematol. 1981 Apr; 9(4):391-410.
    View in: PubMed
  • Segel GB, Lichtman MA. Amino acid transport in human lymphocytes: distinctions in the enhanced uptake with PHA treatment or amino acid deprivation. J Cell Physiol. 1981 Feb; 106(2):303-8.
    View in: PubMed
  • DiPersio JF, Brennan JK, Lichtman MA, Abboud CN, Kirkpatrick FH. The fractionation, characterization, and subcellular localization of colony-stimulating activities released by the human monocyte-like cell line, GCT. Blood. 1980 Oct; 56(4):717-27.
    View in: PubMed
  • Segel GB, Lichtman MA. The apparent discrepancy of ouabain inhibition of cation transport and of lymphocyte proliferation is explained by time-dependency of ouabain binding. J Cell Physiol. 1980 Jul; 104(1):21-6.
    View in: PubMed
  • Segel GB, Lukacher A, Gordon BR, Lichtman MA. Glucocorticoid suppression of human lymphocyte DNA synthesis: influence of phytohemagglutinin concentration. J Lab Clin Med. 1980 Apr; 95(4):624-32.
    View in: PubMed
  • Brennan JK, Lichtman MA, DiPersio JF, Abboud CN. Chemical mediators of granulopoiesis: a review. Exp Hematol. 1980 Apr; 8(4):441-64.
    View in: PubMed
  • Lichtman AH, Segel GB, Lichtman MA. Total and exchangeable calcium in lymphocytes: effects of PHA and A23187. J Supramol Struct. 1980; 14(1):65-75.
    View in: PubMed
  • Abboud CN, DiPersio JF, Brennan JK, Lichtman MA. Erythropoietic enhancing activity (EEA) secreted by the human cell line, GCT. J Supramol Struct. 1980; 13(2):199-209.
    View in: PubMed
  • Abboud CN, Brennan JK, Lichtman MA, Nusbacher J. Quantification of erythroid and granulocytic precursor cells in plateletpheresis residues. Transfusion. 1980 Jan-Feb; 20(1):9-16.
    View in: PubMed
  • Brennan JK, DiPersio JF, Abboud CN, Lichtman MA. The exceptional responsiveness of certain human myeloid leukemia cells to colony-stimulating activity. Blood. 1979 Dec; 54(6):1230-9.
    View in: PubMed
  • Lichtman AH, Segel GB, Lichtman MA. An ultrasensitive method for the measurement of human leukocyte calcium: lymphocytes. Clin Chim Acta. 1979 Oct 1; 97(2-3):107-21.
    View in: PubMed
  • Segel GB, Simon W, Lichtman MA. Regulation of sodium and potassium transport in phytohemagglutinin-stimulated human blood lymphocytes. J Clin Invest. 1979 Sep; 64(3):834-41.
    View in: PubMed
  • Segel GB, Kovach G, Lichtman MA. Sodium-potassium adenosine triphosphatase activity of human lymphocyte membrane vesicles: kinetic parameters, substrate specificity, and effects of phytohemagglutinin. J Cell Physiol. 1979 Jul; 100(1):109-17.
    View in: PubMed
  • Segel GB, Androphy EJ, Lichtman MA. Increased ouabain-sensitive glycolysis of lymphocytes treated with phytohemagglutinin: relationship to potassium transport. J Cell Physiol. 1978 Dec; 97(3 Pt 2 Suppl 1):407-12.
    View in: PubMed
  • Chamberlain JK, Lichtman MA. Marrow cell egress: specificity of the site of penetration into the sinus. Blood. 1978 Nov; 52(5):959-68.
    View in: PubMed
  • Daniel A, Cohen J, Lichtman MA, Murphy MS, Schreiner BF, Shah PM. The relationships among arterial oxygen flow rate, oxygen binding by hemoglobin, and oxygen utilization in chronic cardiac decompensation. J Lab Clin Med. 1978 Apr; 91(4):635-49.
    View in: PubMed
  • Di Persio JF, Brennan JK, Lichtman MA, Speiser BL. Human cell lines that elaborate colon-stimulating activity for the marrow cells of man and other species. Blood. 1978 Mar; 51(3):507-19.
    View in: PubMed
  • Segel GB, Lichtman MA. The effect of method on the measurement of K+ concentration in PHA-treated human blood lymphocytes. Exp Cell Res. 1978 Mar 1; 112(1):95-102.
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  • Gordon BR, Segel GB, Brennan JK, Lichtman MA. Effect of molecular modification on the inhibition of lymphocyte blastogenesis by cardiac glycosides. Blood. 1978 Mar; 51(3):497-505.
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  • Lichtman MA, Chamberlain JK, Simon W, Santillo PA. Parasinusoidal location of megakaryocytes in marrow: a determinant of platelet release. Am J Hematol. 1978; 4(4):303-12.
    View in: PubMed
  • Solomon JR, Lichtman M. Nursing home nucleus generates array of outreach services. Hospitals. 1977 Dec 16; 51(24):85-6, 88, 90.
    View in: PubMed
  • Segel GB, Lichtman MA. Decreased membrane potassium permeability and transport in human chronic leukemic and tonsillar lymphocytes. J Cell Physiol. 1977 Nov; 93(2):277-84.
    View in: PubMed
  • Lichtman MA, Chamberlain JK, Weed RI, Pincus A, Santillo PA. The regulation of the release of granulocytes from normal marrow. Prog Clin Biol Res. 1977; 13:53-75.
    View in: PubMed
  • Lichtman MA, Chamberlain JK, Weed RI, Pincus A, Santillo PA. The regulation of the release of granulocytes from normal marrow. Prog Clin Biol Res. 1977; 13:53-75.
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  • Lichtman MA, Chamberlain JK, Simon W, Santillo PA. The parasinusoidal location of megakaryocytes in marrow: a determinant of platelet release and a physiologic version of vascular invasion and metastasis. Trans Assoc Am Physicians. 1977; 90:313-23.
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  • Segel GB, Lichtman MA. Potasssium transport in human blood lymphocytes treated with phytohemagglutinin. J Clin Invest. 1976 Dec; 58(6):1358-69.
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  • Peck WA, Rockwell LH, Lichtman MA. Adaptive enhancement of amino acid uptake and exodus by thymic lymphocytes: influence of pH. J Cell Physiol. 1976 Nov; 89(3):417-27.
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  • Lightman MA, Murphy MS. Reduced red cell membrane potential and acidification of the plasma in response to contrast materials. Time course of the alteration in plasma pH. Invest Radiol. 1976 Nov-Dec; 11(6):588-93.
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  • Segel GB, Lichtman MA, Gordon BR, MacPherson JL, Nusbacher J. Plateletpheresis residues: a source of large quantities of human blood lymphocytes. Transfusion. 1976 Sep-Oct; 16(5):455-9.
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  • Grammens GL, Brennan JK, Lichtman MA. Inhibitory activity in human marrow plasma directed against mouse marrow cell proliferation: reduced in subjects with decreased granulopoiesis. Nouv Rev Fr Hematol. 1976 Jun; 16(1):37-46.
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  • Segel GB, Lichtman MA, Hollander MM, Gordon BR, Klemperer MR. Human lymphocyte potassium content during the initiation of phytohemagglutinin-induced mitogenesis. J Cell Physiol. 1976 May; 88(1):43-8.
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  • Lichtman MA, Murphy MS, Adamson JW. Detection of mutant hemoglobins with altered affinity for oxygen. A simplified technique. Ann Intern Med. 1976 May; 84(5):517-20.
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  • Segel GB, Gordon BR, Lichtman MA, Hollander MM, Klemperer MR. Exodus of 42K+ and 86Rb+ from rat thymic and human blood lymphocytes exposed to phytohemagglutinin. J Cell Physiol. 1976 Mar; 87(3):337-43.
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  • Brennan JK, Lichtman MA, Chamberlain JK, Leblond P. Isolation of variant lymphoma cells with reduced growth requirements for extracellular calcium and magnesium and enhanced oncogenicity. Blood. 1976 Mar; 47(3):447-59.
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  • Lichtman MA, Murphy M, Pogal M. The use of a single venous blood sample to assess oxygen binding in haemoglobin. Br J Haematol. 1976 Jan; 32(1):89-98.
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  • Frengley PA, Lichtman MA, Peck WA. Adaptive enhancement of amino acid transport in human leukemia leukocytes: studies with alpha-aminoisobutyric acid. J Lab Clin Med. 1975 Dec; 86(6):984-6.
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  • Lichtman MA, Murphy MS, Whitbeck AA, Pogal M, Lipchik EO. Acidification of plasma by the red cell due to radiographic contrast materials. Circulation. 1975 Nov; 52(5):943-50.
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  • Lichtman MA. Does ATP decrease exponentially during red cell aging? Nouv Rev Fr Hematol. 1975 Nov-Dec; 15(6):625-32.
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  • Brennan JK, Mansky J, Roberts G, Lichtman MA. Improved methods for reducing calcium and magnesium concentrations in tissue culture medium: application to studies of lymphoblast proliferation in vitro. In Vitro. 1975 Nov-Dec; 11(6):354-60.
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  • Segel GB, Hollander MM, Gordon BR, Klemperer MR, Lichtman MA. A rapid phytohemagglutinin induced alteration in lymphocyte potassium permeability. J Cell Physiol. 1975 Oct; 86(2 PT 2 SUPPL 1):327-35.
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  • Lichtman MA, Whitbeck AA, Murphy M. Factitious changes in binding of oxygen to hemoglobin when based on extracellular pH in the presence of certain blood additives like radiographic contrast media. Invest Radiol. 1975 May-Jun; 10(3):225-30.
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  • Cuff JM, Lichtman A. The early effects of ouabain on potassium metabolism and rate of proliferation of mouse lymphoblasts. J Cell Physiol. 1975 Apr; 85(2 Pt 1):209-15.
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  • Cuff JM, Lichtman MA. Adaptation of potassium metabolism and restoration of mitosis during prolonged treatment of mouse lymphoblasts with ouabain. J Cell Physiol. 1975 Apr; 85(2 Pt 1):217-26.
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  • Cuff JM, Lichtman MA. The effects of ouabain on the cell mitotic cycle of mouse lymphoblasts. J Cell Physiol. 1975 Apr; 85(2 Pt 1):227-34.
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  • Lichtman MA. The effect of hemodialysis on intraerythrocytic phosphate compounds and oxygen binding to hemoglobin. Kidney Int Suppl. 1975 Jan; (2):134-7.
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  • Lichtman MA, Lipchik EO. Acidification of plasma by the red cell in the presence of radiographic contrast materials: a possible cause of adverse effects on the heart. Trans Assoc Am Physicians. 1975; 88:265-70.
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  • Feldman MJ, Kraetsch RE, Lichtman MA, Peck WA. Uptake of 3-0-methyl-14C-D-glucose by rat thymic lymphocytes: insensitivity to cortisol and inhibitors of ribonucleic acid and protein synthesis, and senstivity to cytochalasin B. J Reticuloendothel Soc. 1974 Dec; 16(6):318-26.
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  • Frengley PA, Peck WA, Lichtman MA. Accelerated active transport of alpha aminoisobutyric acid by human leukemic leukocytes in an amino acid deficient environment. Exp Cell Res. 1974 Oct; 88(2):442-4.
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  • Lichtman MA, Cohen J, Young JA, Whitbeck AA, Murphy M. The relationships between arterial oxygen flow rate, oxygen binding by hemoglobin, and oxygen utilization after myocardial infarction. J Clin Invest. 1974 Sep; 54(3):501-13.
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  • Lichtman MA, Murphy MS, Whitbeck AA, Kearney EA. Oxygen binding to haemoglobin in subjects with hypoproliferative anaemia, with and without chronic renal disease: role of pH. Br J Haematol. 1974 Jul; 27(3):439-52.
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  • Lichtman MA. Editorial: Hypoalimentation during hyperalimentation. N Engl J Med. 1974 Jun 20; 290(25):1432-3.
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  • Lichtman MA, Cohen J, Murphy MS, Kearney EA, Whitbeck AA. Effect of propranolol on oxygen binding to hemoglobin in vitro and in vivo. Circulation. 1974 May; 49(5):881-6.
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  • Lichtman MA, Murphy MS, Byer BJ, Freeman RB. Hemoglobin affinity for oxygen in chronic renal disease: the effect of hemodialysis. Blood. 1974 Mar; 43(3):417-24.
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  • Lichtman MA, Cohen J, Young JA, Yu PN. Reduced arterial oxygen flow and respiratory alkalosis following myocardial infarction: role of hemoglobin-oxygen affinity in the maintenance of oxygen consumption. Trans Assoc Am Physicians. 1974; 87:233-47.
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  • Giordano GF, Lichtman MA. The role of sulfhydryl groups in human neutrophil adhesion, movement and particle ingestion. J Cell Physiol. 1973 Dec; 82(3):387-95.
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  • Taft EG, Grossman J, Abraham GN, Leddy JP, Lichtman MA. Pseudoleukocytosis due to cryoprotein crystals. Am J Clin Pathol. 1973 Nov; 60(5):669-71.
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  • Brennan JK, Lichtman MA. The effect of extracellular calcium and magnesium on the proliferation of murine lymphoblasts. J Cell Physiol. 1973 Aug; 82(1):101-12.
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  • Bricker NS. The time for reflection: a luxury of the past. J Clin Invest. 1973 Jun; 52(6):1518-25.
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  • Young JA, Lichtman MA, Cohen J. Reduced red cell 2,3-diphosphoglycerate and adenosine triphosphate, hypophosphatemia, and increased hemoglobin-oxygen affinity after cardiac surgery. Circulation. 1973 Jun; 47(6):1313-8.
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  • Baran DT, Peck WA, Frengley PA, Lichtman MA. Cortisol-induced inhibition of amino acid transport in thymic lymphocytes: kinetic parameters; relation to ATP levels and protein synthesis; and specificity. Biochim Biophys Acta. 1973 May 25; 307(3):627-39.
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  • Giordano GF, Lichtman MA. Marrow cell egress. The central interaction of barrier pore size and cell maturation. J Clin Invest. 1973 May; 52(5):1154-64.
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  • Lightman MA. Rheology of leukocytes, leukocyte suspensions, and blood in leukemia. Possible relationship to clinical manifestations. J Clin Invest. 1973 Feb; 52(2):350-8.
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  • Lichtman MA, Jackson AH, Peck WA. Lymphocyte monovalent cation metabolism: cell volume, cation content and cation transport. J Cell Physiol. 1972 Dec; 80(3):383-96.
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  • Lichtman MA, Marinetti GV. Erythrocyte shape alteration "in vitro": relationship to plasma and cellular factors. Abstract. Nouv Rev Fr Hematol. 1972 Nov-Dec; 12(6):755-6.
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  • Lichtman MA, Weed RI. Divalent cation content of normal and ATP-depleted erythrocytes and erythrocyte membranes. Nouv Rev Fr Hematol. 1972 Nov-Dec; 12(6):799-813.
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  • Baran DT, Lichtman MA, Peck WA. Alpha-aminoisobutyric acid transport in human leukemic lymphocytes: in vitro characteristics and inhibition by cortisol and cycloheximide. J Clin Invest. 1972 Aug; 51(8):2181-9.
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  • Lichtman MA, Weed RI. Peripheral cytoplasmic characteristics of leukocytes in monocytic leukemia: relationship to clinical manifestations. Blood. 1972 Jul; 40(1):52-61.
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  • Lichtman MA, Weed RI. Alteration of the cell periphery during granulocyte maturation: relationship to cell function. Blood. 1972 Mar; 39(3):301-16.
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  • Oken MM, Lichtman MA, Miller DR, Leblond P. Spherocytic hemolytic disease during magnesium deprivation in the rat. Blood. 1971 Oct; 38(4):468-78.
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  • Miller DR, Rickles FR, Lichtman MA, La Celle PL, Bates J, Weed RI. A new variant of hereditary hemolytic anemia with stomatocytosis and erythrocyte cation abnormality. Blood. 1971 Aug; 38(2):184-204.
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  • Lichtman MA, Miller DR, Cohen J, Waterhouse C. Reduced red cell glycolysis, 2, 3-diphosphoglycerate and adenosine triphosphate concentration, and increased hemoglobin-oxygen affinity caused by hypophosphatemia. Ann Intern Med. 1971 Apr; 74(4):562-8.
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  • Lichtman MA. Cellular deformability during maturation of the myeloblast. Possible role in marrow egress. N Engl J Med. 1970 Oct 29; 283(18):943-8.
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  • Lichtman MA, Miller DR. Erythrocyte glycolysis, 2,3-diphosphoglycerate and adenosine triphosphate concentration in uremic subjects: relationship to extracellular phosphate concentration. J Lab Clin Med. 1970 Aug; 76(2):267-79.
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  • Lichtman MA, Weed RI. Electrophoretic mobility and N-acetyl neuraminic acid content of human normal and leukemic lymphocytes and granulocytes. Blood. 1970 Jan; 35(1):12-22.
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  • Lichtman MA, Weed RI. The monovalent cation content and adenosine triphosphatase activity of human normal and leukemic granulocytes and lymphocytes: relationship to cell volume and morphologic age. Blood. 1969 Nov; 34(5):645-60.
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  • Lichtman MA, Miller DR, Freeman RB. "Mountain sickness" at low altitude due to hypophosphatemia. N Engl J Med. 1969 Sep 4; 281(10):567.
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  • Lichtman MA, Miller DR, Freeman RB. Erythrocyte adenosine triphosphate depletion during hypophosphatemia in a uremic subject. N Engl J Med. 1969 Jan 30; 280(5):240-4.
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  • Lichtman MA, Miller DR, Weed RI. Energy metabolism in uremic red cells: relationship of red cell adenosine triphosphate concentration to extracellular phosphate. Trans Assoc Am Physicians. 1969; 82:331-43.
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  • Lichtman MA, Hoyer LW, Sears DA. Erythrocyte deformation and hemolytic anemia coincident with the microvascular disease of rejecting renal homotransplants. Am J Med Sci. 1968 Oct; 256(4):239-46.
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  • Lichtman MA, Vaughan JH, Hames CG. The distribution of serum immunoglobulins, anti-gamma-G globulins ("rheumatoid factors") and antinuclear antibodies in White and Negro subjects in Evans County, Georgia. Arthritis Rheum. 1967 Jun; 10(3):204-15.
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  • Lichtman MA, Woods JW. Catecholamine excretion in young white and Negro males with normal and elevated blood pressure. J Chronic Dis. 1967 Mar; 20(3):119-28.
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  • LICHTMAN MA, HAMES CG, MCDONOUGH JR. SERUM PROTEIN ELECTROPHORETIC FRACTIONS AMONG NEGRO AND WHITE SUBJECT IN EVANS COUNTY, GEORGIA. Am J Clin Nutr. 1965 Jun; 16:492-508.
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  • MCDONOUGH JR, HAMES CG, GARRISON GE, STULB SC, LICHTMAN MA, HEFELFINGER DC. GRAND ROUNDS AT BARNES HOSPITAL. II. MUSCULAR SUBAORTIC STENOSIS. J Chronic Dis. 1965 Mar; 18:267-74.
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  • MCDONOUGH JR, HAMES CG, GARRISON GE, STULB SC, LICHTMAN MA, HEFELFINGER DC. THE RELATIONSHIP OF HEMATOCRIT TO CARDIOVASCULAR STATES OF HEALTH IN THE NEGRO AND WHITE POPULATION OF EVANS COUNTY, GEORGIA. J Chronic Dis. 1965 Mar; 18:243-57.
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  • MCDONOUGH JR, HAMES CG, GARRISON GE, STULB SC, LICHTMAN MA, HEFELFINGER DC. GRAND ROUNDS AT BARNES HOSPITAL. I. PERIODIC FEVER. J Chronic Dis. 1965 Mar; 18:261-7.
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  • SLAUNWHITE WR, LICHTMAN MA, SANDBERG AA. STUDIES ON PHENOLIC STEROIDS IN HUMAN SUBJECTS. VI. BIOSYNTHESIS OF ESTRIOLGLUCOSIDURONIC ACID-16-C-14 BY HUMAN LIVER. J Clin Endocrinol Metab. 1964 Jul; 24:638-43.
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