Dr. Bisognano is a Professor of Medicine and Director of Cardiac Rehabilitation and Clinical Preventive Cardiology. He joined the faculty in September 2001 from the University of Michigan where he participated in the Hypertension and Vascular Medicine Program as well as the Heart Failure and Transplantation Program.

Dr. Bisognano's research focuses on cardiovascular risk factor reduction, with a particular interest on improving compliance with the national guidelines for the treatment of hypertension. He is also interested in the etiology of hypertensive urgencies and emergencies, including the development of evidence-based treatment protocols for office patients with severely elevated blood pressure but no evidence of ongoing target organ damage. Additionally, he is interested in a community-based education program in the evaluation and treatment of hypertension, noting that only a small fraction of patients with hypertension achieve the blood pressure goals suggested by the national guidelines.

Dr. Bisognano is Upstate Governor for the New York American College of Cardiology through March 31, 2012. He is also the President, of the New York Cardiological Society, effective September 30, 2010 – March 31, 2012, and the President of theNew York Chapter, American College of Cardiology, present to September 30, 2010 through March 31, 2012.

• Lien SF, Bisognano JD. Perioperative hypertension: defining at-risk patients and their management. Curr Hypertens Rep. 2012 Oct; 14(5):432-41.
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• Davidson AC, Bisognano JD. Interventional approaches for resistant hypertension. Curr Opin Nephrol Hypertens. 2012 Sep; 21(5):475-80.
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• Gassler JP, Lynch PS, Bisognano JD. The role of baroreflex activation therapy in sympathetic modulation for the treatment of resistant hypertension. Heart. 2012 Dec; 98(23):1689-92.
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• Woolf KJ, Zabad MN, Post JM, McNitt S, Williams GC, Bisognano JD. Effect of nicotine replacement therapy on cardiovascular outcomes after acute coronary syndromes. Am J Cardiol. 2012 Oct 1; 110(7):968-70.
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• Rich DQ, Zareba W, Beckett W, Hopke PK, Oakes D, Frampton MW, Bisognano J, Chalupa D, Bausch J, O'Shea K, Wang Y, Utell MJ. Are ambient ultrafine, accumulation mode, and fine particles associated with adverse cardiac responses in patients undergoing cardiac rehabilitation? Environ Health Perspect. 2012 Aug; 120(8):1162-9.
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• Bakris GL, Nadim MK, Haller H, Lovett EG, Schafer JE, Bisognano JD. Baroreflex Activation Therapy provides durable benefit in patients with resistant hypertension: results of long-term follow-up in the Rheos Pivotal Trial. J Am Soc Hypertens. 2012 Mar; 6(2):152-8.
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• Bisognano JD, Speranza PS, Becker LM, Norwood WS, Bradley A, Nazar MD, Beckman HB. Creating community collaboration to improve the care of patients with high blood pressure: lessons from Rochester, new york. J Clin Hypertens (Greenwich). 2012 Mar; 14(3):178-83.
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• Woolf KJ, Bisognano JD. Nondrug interventions for treatment of hypertension. J Clin Hypertens (Greenwich). 2011 Nov; 13(11):829-35.
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• Bisognano JD, Bakris G, Nadim MK, Sanchez L, Kroon AA, Schafer J, de Leeuw PW, Sica DA. Baroreflex activation therapy lowers blood pressure in patients with resistant hypertension: results from the double-blind, randomized, placebo-controlled rheos pivotal trial. J Am Coll Cardiol. 2011 Aug 9; 58(7):765-73.
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• Bisognano JD, Kaufman CL, Bach DS, Lovett EG, de Leeuw P. Improved cardiac structure and function with chronic treatment using an implantable device in resistant hypertension: results from European and United States trials of the Rheos system. J Am Coll Cardiol. 2011 Apr 26; 57(17):1787-8.
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• Gewirtz JR, Bisognano JD. Catheter-based renal sympathetic denervation: a targeted approach to resistant hypertension. Cardiol J. 2011; 18(1):97-102.
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• Taylor JG, Bisognano JD. Baroreflex stimulation in antihypertensive treatment. Curr Hypertens Rep. 2010 Jun; 12(3):176-81.
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• McClintic BR, McClintic JI, Bisognano JD, Block RC. The relationship between retinal microvascular abnormalities and coronary heart disease: a review. Am J Med. 2010 Apr; 123(4):374.e1-7.
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• Bergset J, Storozynsky E, Bisognano JD. Renin inhibition for hypertension: selecting the right role for a new class of drug. Am J Ther. 2010 Mar-Apr; 17(2):182-7.
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• Nelson R, Antonetti I, Bisognano JD, Sloand J. Obesity-related cardiorenal syndrome. J Clin Hypertens (Greenwich). 2010 Jan; 12(1):59-63.
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• Baker ML, Wormer D, Bisognano JD. Thromboembolic events of mitral valve endocarditis. Cardiol J. 2010; 17(2):192-3.
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• Aung T, Bisognano JD, Morgan MA. Allergic respiratory disease as a potential co-morbidity for hypertension. Cardiol J. 2010; 17(5):443-7.
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• Rao M, Rajda G, Uppuluri S, Beck GR, Liu L, Bisognano JD. The role of continuous positive airway pressure in the treatment of hypertension in patients with obstructive sleep apnea-hypoapnea syndrome: a review of randomized trials. Rev Recent Clin Trials. 2010 Jan; 5(1):35-42.
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• Yoder SR, Thornburg LL, Bisognano JD. Hypertension in pregnancy and women of childbearing age. Am J Med. 2009 Oct; 122(10):890-5.
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• Young KC, Teeters JC, Benesch CG, Bisognano JD, Illig KA. Cost-effectiveness of treating resistant hypertension with an implantable carotid body stimulator. J Clin Hypertens (Greenwich). 2009 Oct; 11(10):555-63.
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• Ban-Hoefen M, Bernstein SH, Bisognano JD, Pryor JG, Friedberg JW. Symptomatic intracardiac diffuse large B-cell lymphoma. Am J Hematol. 2009 Oct; 84(10):683-5.
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• Gassler JP, Bisognano JD. Commentary: revisiting the early morning blood pressure surge and myocardial ischemia. J Clin Hypertens (Greenwich). 2009 Jul; 11(7):348-50.
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• Zareba KM, Shenkman HJ, Bisognano JD. Comparison of acute electrocardiographic presentation in patients with diastolic vs systolic heart failure. Congest Heart Fail. 2009 Jul-Aug; 15(4):165-9.
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• Joshi N, Taylor J, Bisognano JD. Implantable device therapy for the treatment of resistant hypertension. J Cardiovasc Transl Res. 2009 Jun; 2(2):150-3.
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• Azzara CD, Nickels MW, Bisognano JD. Labile hypertension: lessons to be learned from musical improvisation. J Clin Hypertens (Greenwich). 2009 Mar; 11(3):113-5.
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• Jindal V, Baker ML, Aryangat A, Wittlin SD, Bisognano JD, Richter HS. Pheochromocytoma: presenting with regular cyclic blood pressure and inverted Takotsubo cardiomyopathy. J Clin Hypertens (Greenwich). 2009 Feb; 11(2):81-6.
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• Uppuluri SC, Storozynsky E, Bisognano JD. Baroreflex device therapy in the treatment of hypertension. Curr Hypertens Rep. 2009 Feb; 11(1):69-75.
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• Hong JA, Bisognano JD. Metoprolol succinate therapy associated with erythema multiforme. Cardiol J. 2009; 16(1):82-3.
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• Zeglin MA, Pacos J, Bisognano JD. Hypertension in the very elderly: Brief review of management. Cardiol J. 2009; 16(4):379-85.
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• Navaneethan SD, Lohmeier TE, Bisognano JD. Baroreflex stimulation: A novel treatment option for resistant hypertension. J Am Soc Hypertens. 2009 Jan-Feb; 3(1):69-74.
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• Dockery BK, Bisognano JD. Direct renin inhibition: an analysis of possible benefits. Curr Hypertens Rep. 2008 Aug; 10(4):313-8.
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• Zareba KM, Shenkman HJ, Bisognano JD. Predictive value of admission electrocardiography in patients with heart failure. Congest Heart Fail. 2008 Jul-Aug; 14(4):173-9.
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• Maki KC, Curry LL, Carakostas MC, Tarka SM, Reeves MS, Farmer MV, McKenney JM, Toth PD, Schwartz SL, Lubin BC, Dicklin MR, Boileau AC, Bisognano JD. The hemodynamic effects of rebaudioside A in healthy adults with normal and low-normal blood pressure. Food Chem Toxicol. 2008 Jul; 46 Suppl 7:S40-6.
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• Ban-Hoefen M, Zeglin MA, Bisognano JD. Diffuse large B cell lymphoma presenting as a cardiac mass and odynophagia. Cardiol J. 2008; 15(5):471-4.
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• Sloand JA, Illig KA, Bisognano JD. Improved control of resistant hypertension with device-mediated electrical carotid sinus baroreflex stimulation. J Clin Hypertens (Greenwich). 2007 Sep; 9(9):716-9.
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• Filippone JD, Bisognano JD. Baroreflex stimulation in the treatment of hypertension. Curr Opin Nephrol Hypertens. 2007 Sep; 16(5):403-8.
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• Sloand JA, Bisognano JD. Vascular disease in an expanding world: seeking answers inside and outside of the box. J Clin Hypertens (Greenwich). 2007 Apr; 9(4):246-8.
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• Shenkman HJ, Zareba W, Bisognano JD. Comparison of prognostic significance of amino-terminal pro-brain natriuretic Peptide versus blood urea nitrogen for predicting events in patients hospitalized for heart failure. Am J Cardiol. 2007 Apr 15; 99(8):1143-5.
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• Bisognano JD, Townsend KA, Skyles AJ, Samuels KM. Prevalence of comorbidities and their influence on blood pressure goal attainment in geriatric patients. Am J Geriatr Cardiol. 2007 Jan-Feb; 16(1):24-9.
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• Sloand JA, Balakrishnan SL, Fong MW, Bisognano JD. Evaluation and treatment of resistant hypertension. Cardiol J. 2007; 14(4):329-30.
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• Fong MW, Filippone JD, Beck GR, Katz MG, Bisognano JD. Improving care in resistant hypertension: medication trends and nonpharmacologic strategies in a specialty clinic. Am J Cardiovasc Drugs. 2007; 7(6):449-52.
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• Bisognano JD, McLaughlin T, Roberts CS, Tang SS. Calcium channel blockers, angiotensin receptor blockers, and angiotensin-converting enzyme inhibitors: effectiveness in combination with diuretics or beta-blockers for treating hypertension. Vasc Health Risk Manag. 2007; 3(5):579-85.
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• Filippone JD, Sloand JA, Illig KA, Bisognano JD. Electrical stimulation of the carotid sinus for the treatment of resistant hypertension. Curr Hypertens Rep. 2006 Oct; 8(5):420-4.
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• Moser M, Izzo JL, Bisognano J. Hypertensive emergencies. J Clin Hypertens (Greenwich). 2006 Apr; 8(4):275-81.
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• Vorobiof G, Blaxall BC, Bisognano JD. The future of endothelin-receptor antagonism as treatment for systemic hypertension. Curr Hypertens Rep. 2006 Apr; 8(1):35-44.
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• Bender SR, Fong MW, Heitz S, Bisognano JD. Characteristics and management of patients presenting to the emergency department with hypertensive urgency. J Clin Hypertens (Greenwich). 2006 Jan; 8(1):12-8.
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• Bisognano JD, McGrody KS, Spence AM. Myocarditis from the Chinese sumac tree. Ann Intern Med. 2005 Jul 19; 143(2):159-60.
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• Hill MD, Bisognano JD. Leukoaraiosis: the brain under pressure: target for treatment? Neurology. 2005 Jun 14; 64(11):1832-3.
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• Bisognano JD, Lindenfeld J, Hammond E, Zisman LS. Coronary artery vasospasm causing acute myocardial infarction in a heart transplant recipient. J Heart Lung Transplant. 2005 Mar; 24(3):355-8.
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• Berk BC, Bisognano JD. VALUE in hypertension treatment. Curr Hypertens Rep. 2004 Dec; 6(6):411-3.
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• Valentini M, Julius S, Palatini P, Brook RD, Bard RL, Bisognano JD, Kaciroti N. Attenuation of haemodynamic, metabolic and energy expenditure responses to isoproterenol in patients with hypertension. J Hypertens. 2004 Oct; 22(10):1999-2006.
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• Bisognano J, McLaughlin T, Roberts CS, Battleman D, Schwartz B, Garza D, Tang S. Incremental effectiveness of amlodipine besylate in the treatment of hypertension with single and multiple medication regimens. Am J Hypertens. 2004 Aug; 17(8):676-83.
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• Majahalme SK, Smith DE, Cooper JV, Kline-Rogers E, Mehta RH, Eagle KA, Bisognano JD. Comparison of patients with acute coronary syndrome with and without systemic hypertension. Am J Cardiol. 2003 Aug 1; 92(3):258-63.
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• Bisognano JD, Weinberger HD, Bohlmeyer TJ, Pende A, Raynolds MV, Sastravaha A, Roden R, Asano K, Blaxall BC, Wu SC, Communal C, Singh K, Colucci W, Bristow MR, Port DJ. Myocardial-directed overexpression of the human beta(1)-adrenergic receptor in transgenic mice. J Mol Cell Cardiol. 2000 May; 32(5):817-30.
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• Bisognano JD, Cody RJ. The renin-angiotensin system antagonism in the treatment of hypertension. Curr Hypertens Rep. 1999 Aug; 1(4):275-7.
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• Bisognano JD, Morgan MB, Lowes BD, Wolfel EE, Lindenfeld J, Zisman LS. Acute parvovirus infection in a heart transplant recipient. Transplant Proc. 1999 Aug; 31(5):2159-60.
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• Bisognano JD, Weder AB. Effective treatment of severe hypertension. Prog Cardiovasc Nurs. 1999; 14(4):150-2, 158.
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• Bisognano JD, Merrick DT, Popylisen SL, Hoffman MS, Weinberger HD. Congenital duplication of the tricuspid valve presenting as a circumscribed obstructive mass in the right ventricular outflow tract. J Am Soc Echocardiogr. 1998 May; 11(5):480-2.
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• Bisognano JD, Horwitz LD. Combination therapy with an angiotensin converting enzyme inhibitor and an angiotensin-II receptor antagonist for refractory essential hypertension. West J Med. 1998 Apr; 168(4):272-4.
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• Bisognano JD, Young B, Brown JM, Gill EA, Fang FC, Zisman LS. Diverse presentation of aberrant origin of the right subclavian artery: two case reports. Chest. 1997 Dec; 112(6):1693-7.
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• Pende A, Tremmel KD, DeMaria CT, Blaxall BC, Minobe WA, Sherman JA, Bisognano JD, Bristow MR, Brewer G, Port J. Regulation of the mRNA-binding protein AUF1 by activation of the beta-adrenergic receptor signal transduction pathway. J Biol Chem. 1996 Apr 5; 271(14):8493-501.
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• Freedman JC, Novak TS, Bisognano JD, Pratap PR. Voltage dependence of DIDS-insensitive chloride conductance in human red blood cells treated with valinomycin or gramicidin. J Gen Physiol. 1994 Nov; 104(5):961-83.
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• Bisognano JD, Dix JA, Pratap PR, Novak TS, Freedman JC. Proton (or hydroxide) fluxes and the biphasic osmotic response of human red blood cells. J Gen Physiol. 1993 Jul; 102(1):99-123.
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