Geunyoung Yoon
| Title | Associate Professor |
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| Institution | School of Medicine and Dentistry |
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| Department | Ophthalmology |
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| Title | Associate Professor |
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| Institution | School of Medicine and Dentistry |
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| Department | Biomedical Engineering |
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| Title | Associate Professor |
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| Institution | University of Rochester, River Campus |
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| Department | The Institute of Optics |
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| Title | Associate Professor |
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| Institution | University of Rochester, River Campus |
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| Department | Center for Visual Science A&S |
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Research projects in the Advanced Physiological Optics Laboratory have been focusing on optics of the eye. The goals of the projects are to objectively understand optical quality of the eye and to improve visual performance by correcting the optical defects in the eye with various correction methods. We have successfully developed the large dynamic range wavefront sensor with high measurement sensitivity that allows us to measure highly aberrated eyes such as advanced keratoconus. We have also developed the customized correction methods. These include customized optical components such as phase plate and soft contact lenses, and laser refractive surgery. We recently implemented the large stroke adaptive optics system for vision testing that has sufficient deformable mirror stroke to correct the highly aberrated eyes such as advanced keratoconus. This powerful tool is being used to understand interaction between optics of the eye and adaptation effects of the human visual system. We are currently expanding our research scope to presbyopia, accommodation and dry eye with advanced intraocular imaging system such as Fourier domain optical coherence tomography and high-resolution magnetic resonance imaging. We have also been very active in collaborating with PIs in intramural and extramural research laboratories and industry.
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Sabesan R, Zheleznyak L, Yoon G. Binocular visual performance and summation after correcting higher order aberrations. Biomed Opt Express. 2012 Dec 1; 3(12):3176-89.
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Yadav R, Kottaiyan R, Ahmad K, Yoon G. Epithelium and Bowman's layer thickness and light scatter in keratoconic cornea evaluated using ultrahigh resolution optical coherence tomography. J Biomed Opt. 2012 Nov 1; 17(11):116010.
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Zheleznyak L, Kim MJ, Macrae S, Yoon G. Impact of corneal aberrations on through-focus image quality of presbyopia-correcting intraocular lenses using an adaptive optics bench system. J Cataract Refract Surg. 2012 Oct; 38(10):1724-33.
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Pantanelli SM, Sabesan R, Ching SS, Yoon G, Hindman HB. Visual performance with wave aberration correction after penetrating, deep anterior lamellar, or endothelial keratoplasty. Invest Ophthalmol Vis Sci. 2012 Aug; 53(8):4797-804.
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Koh S, Tung C, Kottaiyan R, Zavislan J, Yoon G, Aquavella J. Effect of airflow exposure on the tear meniscus. J Ophthalmol. 2012; 2012:983182.
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Kottaiyan R, Yoon G, Wang Q, Yadav R, Zavislan JM, Aquavella JV. Integrated multimodal metrology for objective and noninvasive tear evaluation. Ocul Surf. 2012 Jan; 10(1):43-50.
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Kim MJ, Zheleznyak L, Macrae S, Tchah H, Yoon G. Objective evaluation of through-focus optical performance of presbyopia-correcting intraocular lenses using an optical bench system. J Cataract Refract Surg. 2011 Jul; 37(7):1305-12.
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Kim SW, Yang H, Yoon G, Lee YJ, Kweon MN, Kim JK, Seo KY. Higher-order aberration changes after Implantable Collamer Lens implantation for myopia. Am J Ophthalmol. 2011 Apr; 151(4):653-662.e1.
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Yadav R, Ahmad K, Yoon G. Scanning system design for large scan depth anterior segment optical coherence tomography. Opt Lett. 2010 Jun 1; 35(11):1774-6.
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Bühren J, Yoon G, MacRae S, Huxlin K. Contribution of optical zone decentration and pupil dilation on the change of optical quality after myopic photorefractive keratectomy in a cat model. J Refract Surg. 2010 Mar; 26(3):183-90.
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Koh S, Tung C, Aquavella J, Yadav R, Zavislan J, Yoon G. Simultaneous measurement of tear film dynamics using wavefront sensor and optical coherence tomography. Invest Ophthalmol Vis Sci. 2010 Jul; 51(7):3441-8.
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Bühren J, Kook D, Yoon G, Kohnen T. Detection of subclinical keratoconus by using corneal anterior and posterior surface aberrations and thickness spatial profiles. Invest Ophthalmol Vis Sci. 2010 Jul; 51(7):3424-32.
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Sabesan R, Yoon G. Neural compensation for long-term asymmetric optical blur to improve visual performance in keratoconic eyes. Invest Ophthalmol Vis Sci. 2010 Jul; 51(7):3835-9.
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Bühren J, Nagy L, Yoon G, MacRae S, Kohnen T, Huxlin KR. The effect of the asphericity of myopic laser ablation profiles on the induction of wavefront aberrations. Invest Ophthalmol Vis Sci. 2010 May; 51(5):2805-12.
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Sabesan R, Yoon G. Visual performance after correcting higher order aberrations in keratoconic eyes. J Vis. 2009; 9(5):6.1-10.
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Bühren J, Pesudovs K, Martin T, Strenger A, Yoon G, Kohnen T. Comparison of optical quality metrics to predict subjective quality of vision after laser in situ keratomileusis. J Cataract Refract Surg. 2009 May; 35(5):846-55.
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Tahzib NG, MacRae SM, Yoon G, Berendschot TT, Eggink FA, Hendrikse F, Nuijts RM. Higher-order aberrations after implantation of iris-fixated rigid or foldable phakic intraocular lenses. J Cataract Refract Surg. 2008 Nov; 34(11):1913-20.
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Chen M, Yoon G. Posterior corneal aberrations and their compensation effects on anterior corneal aberrations in keratoconic eyes. Invest Ophthalmol Vis Sci. 2008 Dec; 49(12):5645-52.
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Yoon G, Pantanelli S, MacRae S. Comparison of Zernike and Fourier wavefront reconstruction algorithms in representing corneal aberration of normal and abnormal eyes. J Refract Surg. 2008 Jun; 24(6):582-90.
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Bühren J, Yoon G, Kenner S, MacRae S, Huxlin K. The effect of optical zone decentration on lower- and higher-order aberrations after photorefractive keratectomy in a cat model. Invest Ophthalmol Vis Sci. 2007 Dec; 48(12):5806-14.
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Chen M, Sabesan R, Ahmad K, Yoon G. Correcting anterior corneal aberration and variability of lens movements in keratoconic eyes with back-surface customized soft contact lenses. Opt Lett. 2007 Nov 1; 32(21):3203-5.
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Sabesan R, Ahmad K, Yoon G. Correcting highly aberrated eyes using large-stroke adaptive optics. J Refract Surg. 2007 Nov; 23(9):947-52.
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Doble N, Miller DT, Yoon G, Williams DR. Requirements for discrete actuator and segmented wavefront correctors for aberration compensation in two large populations of human eyes. Appl Opt. 2007 Jul 10; 46(20):4501-14.
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Pantanelli S, MacRae S, Jeong TM, Yoon G. Characterizing the wave aberration in eyes with keratoconus or penetrating keratoplasty using a high-dynamic range wavefront sensor. Ophthalmology. 2007 Nov; 114(11):2013-21.
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Nagy LJ, MacRae S, Yoon G, Wyble M, Wang J, Cox I, Huxlin KR. Photorefractive keratectomy in the cat eye: biological and optical outcomes. J Cataract Refract Surg. 2007 Jun; 33(6):1051-64.
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Sabesan R, Jeong TM, Carvalho L, Cox IG, Williams DR, Yoon G. Vision improvement by correcting higher-order aberrations with customized soft contact lenses in keratoconic eyes. Opt Lett. 2007 Apr 15; 32(8):1000-2.
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Carvalho LA, Yoon G. [Measuring the refractive power of customized soft contact lenses]. Arq Bras Oftalmol. 2007 Jan-Feb; 70(1):67-72.
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Chung SH, Lee IS, Lee YG, Lee HK, Kim EK, Yoon G, Seo KY. Comparison of higher-order aberrations after wavefront-guided laser in situ keratomileusis and laser-assisted subepithelial keratectomy. J Cataract Refract Surg. 2006 May; 32(5):779-84.
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Yoon G, Pantanelli S, Nagy LJ. Large-dynamic-range Shack-Hartmann wavefront sensor for highly aberrated eyes. J Biomed Opt. 2006 May-Jun; 11(3):30502.
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Padmanabhan P, Yoon G, Porter J, Rao SK, Roy J, Choudhury M. Wavefront aberrations in eyes with Acrysof monofocal intraocular lenses. J Refract Surg. 2006 Mar; 22(3):237-42.
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Porter J, Yoon G, Lozano D, Wolfing J, Tumbar R, Macrae S, Cox IG, Williams DR. Aberrations induced in wavefront-guided laser refractive surgery due to shifts between natural and dilated pupil center locations. J Cataract Refract Surg. 2006 Jan; 32(1):21-32.
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Porter J, Yoon G, MacRae S, Pan G, Twietmeyer T, Cox IG, Williams DR. Surgeon offsets and dynamic eye movements in laser refractive surgery. J Cataract Refract Surg. 2005 Nov; 31(11):2058-66.
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Jeong TM, Menon M, Yoon G. Measurement of wave-front aberration in soft contact lenses by use of a Shack-Hartmann wave-front sensor. Appl Opt. 2005 Jul 20; 44(21):4523-7.
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Yoon G, Macrae S, Williams DR, Cox IG. Causes of spherical aberration induced by laser refractive surgery. J Cataract Refract Surg. 2005 Jan; 31(1):127-35.
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Yoon G, Jeong TM, Cox IG, Williams DR. Vision improvement by correcting higher-order aberrations with phase plates in normal eyes. J Refract Surg. 2004 Sep-Oct; 20(5):S523-7.
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Huxlin KR, Yoon G, Nagy L, Porter J, Williams D. Monochromatic ocular wavefront aberrations in the awake-behaving cat. Vision Res. 2004; 44(18):2159-69.
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Porter J, MacRae S, Yoon G, Roberts C, Cox IG, Williams DR. Separate effects of the microkeratome incision and laser ablation on the eye's wave aberration. Am J Ophthalmol. 2003 Aug; 136(2):327-37.
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Doble N, Yoon G, Chen L, Bierden P, Singer B, Olivier S, Williams DR. Use of a microelectromechanical mirror for adaptive optics in the human eye. Opt Lett. 2002 Sep 1; 27(17):1537-9.
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Yoon GY, Williams DR. Visual performance after correcting the monochromatic and chromatic aberrations of the eye. J Opt Soc Am A Opt Image Sci Vis. 2002 Feb; 19(2):266-75.
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Hofer H, Chen L, Yoon GY, Singer B, Yamauchi Y, Williams DR. Improvement in retinal image quality with dynamic correction of the eye's aberrations. Opt Express. 2001 May 21; 8(11):631-43.
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Williams D, Yoon GY, Porter J, Guirao A, Hofer H, Cox I. Visual benefit of correcting higher order aberrations of the eye. J Refract Surg. 2000 Sep-Oct; 16(5):S554-9.
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