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Jill Cholette

TitleAssistant Professor
InstitutionSchool of Medicine and Dentistry
DepartmentPediatrics
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 667
Rochester NY 14642
 
 Awards And Honors
1992     Abbey Howe Turner Award excellence in biological sciences
1993     Sarah Williston Scholar for academic excellence
1993 - 1994Who's Who Among Students in American Universities & Colleges
1994     Psi Chi, The National Honor Society in Psychology
1995     Sigma Xi, The Scientific Research Society
1999     Alpha Omega Alpha Honors Medical Society
1999     The Bryce Collier Prize (student whose performance demonstrates exceptional qualitites of responsibility
1999     The Benjamin Rush Prize (4th yr med student who gave unusual promise of creative scholars
1999     The Glasgow Citation (awarded by the American Medical Women's Assoc to those whose academic work is high quality
1999     American Medical Women's Association Award
2000     David A. Haller Award - outstanding devotion and contribution to patient care
2005     Clausen-Bradford Fellowship Training Award
2007 - 2010Strong Children's Research Center New Investigator  | URMC
2012     Therapeutics Specialty Award  | Society of Critical Care Medicine
2012     Research Citation Finalist  | Society of Critical Care Medicine
 
 Overview
Dr. Jill Cholette has research interests in thrombosis and use of blood products in critically ill pediatric patients, particularly those undergoing cardiac surgery. Dr. Cholette is working to clarify the role of inflammation in the development of thrombosis, and to determine the optimal anticoagulation regimen for the pediatric post-op cardiac surgery patient.

Her other work involves blood utilization in the pediatric ICU patient, and she is developing a transfusion strategy for the pediatric post-op cardiac surgery patients.

Dr. Cholette's clinical interests are: thrombosis, hemostasis, and inflammation.

Scientific Reviewer for Pediatric Clinical Research Organization (PCRO) at URMC 2009-present

Scientific Reviewer for Strong Children's Research Center Small Grant Program URMC June 2013

Journal Reviewer:
The Annals of Thoracic Surgery 2007-present
Thrombosis Research 2008-present
Postgraduate Medicine 2009-present

Pediatric Acute Lung Injury and Sepsis (PALISI) Member
March 2010-present

Pediatric Blood Research Network (BLOOD NET) Member
September 2011-present

Prevalence of Acute critical Neurologic disease in children: a Global Epidemiological Assessment (PANGEA). November 2011-present; PI: Erika Fink; University of Pittsburgh
Site PI: Jill M. Cholette

Prophylaxis against thrombosis practice (PROTRACT) Study February 2012-present
PI: Vince Faustino MD; Yale University Site PI: Jill M. Cholette

Ongoing studies:
Prospective randomized controlled clinical trial comparing a restrictive v. liberal transfusion strategy in neonates and infants undergoing surgery for congenital heart disease. Principle Investigator: Cholette JM

Impact of washed blood on outcomes in adults with acute leukemia.
Co-principle investigator: Cholette JM

Comparing Ultrasound Dilution with Fick Principle in Assessing Cardiac Output and Shunt Fraction in Patients with Congenital Heart Disease.
Co-investigator Cholette JM.

Identification and significance of biologic mediators in red cell concentrates.
Co-investigator: Cholette JM

An investigation of the adverse effects of the storage age of RBC transfusions to critically ill medical patients.
Co-investigator: Cholette JM

 
 Selected Publications
List All   |   Timeline
  1. Lehoux J, Swartz MF, Atallah-Yunes N, Cholette JM, Alfieris GM. Regression of left ventricular hypertrophy in children following the Ross procedure. Interact Cardiovasc Thorac Surg. 2014 May; 18(5):607-10.
    View in: PubMed
  2. Walters AM, Swartz MF, Patel S, Cholette JM, Atallah-Yunes N, Alfieris GM. Risk factors for a positive neoaortic arch gradient after stage I palliation for hypoplastic left heart syndrome. Ann Thorac Surg. 2013 Aug; 96(2):645-50.
    View in: PubMed
  3. Swartz MF, Morrow D, Atallah-Yunes N, Cholette JM, Gensini F, Kavey RE, Alfieris GM. Hypertensive changes within the aortic arch of infants and children with isolated coarctation. Ann Thorac Surg. 2013 Jul; 96(1):190-5.
    View in: PubMed
  4. Cholette JM, Powers KS, Alfieris GM, Angona R, Henrichs KF, Masel D, Swartz MF, Daugherty LE, Belmont K, Blumberg N. Transfusion of Cell Saver Salvaged Blood in Neonates and Infants Undergoing Open Heart Surgery Significantly Reduces RBC and Coagulant Product Transfusions and Donor Exposures: Results of a Prospective, Randomized, Clinical Trial*. Pediatr Crit Care Med. 2013 Feb; 14(2):137-47.
    View in: PubMed
  5. Swartz MF, Sena A, Atallah-Yunes N, Meagher C, Cholette JM, Gensini F, Alfieris GM. Decreased incidence of supravalvar pulmonary stenosis after arterial switch operation. Circulation. 2012 Sep 11; 126(11 Suppl 1):S118-22.
    View in: PubMed
  6. Swartz MF, Schiralli MP, Angona R, Cholette JM, Gensini F, Alfieris GM. The Effect of Repeat Sternotomy during Right Ventricular Outflow Tract Reconstruction. Congenit Heart Dis. 2013 Mar; 8(2):142-8.
    View in: PubMed
  7. Cholette JM, Henrichs KF, Alfieris GM, Powers KS, Phipps R, Spinelli SL, Swartz M, Gensini F, Daugherty LE, Nazarian E, Rubenstein JS, Sweeney D, Eaton M, Lerner NB, Blumberg N. Washing red blood cells and platelets transfused in cardiac surgery reduces postoperative inflammation and number of transfusions: results of a prospective, randomized, controlled clinical trial. Pediatr Crit Care Med. 2012 May; 13(3):290-9.
    View in: PubMed
  8. Swartz MF, Atallah-Yunes N, Meagher C, Schiralli MP, Cholette J, Orie J, Gensini F, Kavey RE, Alfieris GM. Surgical strategy for aortic coarctation repair resulting in physiologic arm and leg blood pressures. Congenit Heart Dis. 2011 Nov-Dec; 6(6):583-91.
    View in: PubMed
  9. Schiralli MP, Cholette JM, Swartz MF, Vermilion R, Meagher C, Alfieris GM. Carpentier edwards porcine valved conduit for right ventricular outflow tract reconstruction. J Card Surg. 2011 Nov; 26(6):643-9.
    View in: PubMed
  10. Cholette JM, Rubenstein JS, Alfieris GM, Powers KS, Eaton M, Lerner NB. Children with single-ventricle physiology do not benefit from higher hemoglobin levels post cavopulmonary connection: results of a prospective, randomized, controlled trial of a restrictive versus liberal red-cell transfusion strategy. Pediatr Crit Care Med. 2011 Jan; 12(1):39-45.
    View in: PubMed
  11. Alfieris GM, Gangemi JJ, Schiralli MP, Swartz MF, Cholette JM. Modified repair of truncus arteriosus to maintain pulmonary artery architecture. Ann Thorac Surg. 2010 Sep; 90(3):1038-9.
    View in: PubMed
  12. Cholette JM, Mamikonian L, Alfieris GM, Blumberg N, Lerner NB. Aspirin resistance following pediatric cardiac surgery. Thromb Res. 2010 Sep; 126(3):200-6.
    View in: PubMed
  13. Cholette JM, Blumberg N, Phipps RP, McDermott MP, Gettings KF, Lerner NB. Developmental changes in soluble CD40 ligand. J Pediatr. 2008 Jan; 152(1):50-4, 54.e1.
    View in: PubMed
  14. Cholette JM, Rubenstein JS, Alfieris GM, McDermott MP, Harmon WG, Vermilion R, Eaton MP, Gangemi JJ, Lerner NB. Elevated risk of thrombosis in neonates undergoing initial palliative cardiac surgery. Ann Thorac Surg. 2007 Oct; 84(4):1320-5.
    View in: PubMed
  15. Cholette JM, Caserta M, Hardy D, Connolly HV. Outcome of pulmonary function in Lemierre's disease-associated acute respiratory distress syndrome. Pediatr Pulmonol. 2007 Apr; 42(4):389-92.
    View in: PubMed

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