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Mark Taubman

TitleProfessor
InstitutionSchool of Medicine and Dentistry
DepartmentMedicine
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 706
Rochester NY 14642
Other Positions
TitleDean, School of Medicine & Dentistry
InstitutionSchool of Medicine and Dentistry
DepartmentDean's Office, SMD

TitleUniversity Vice President for Health Sciences
InstitutionUniversity of Rochester Medical Center
DepartmentOffice of VP for Health Sciences

 
 Awards And Honors
1972 - 1978NIH Training Grant Medical Scientist Training Program, New York University School of Medicine, New York, NY
1983 - 1984NIH Institutional Training Grant for Cardiovascular Research Brigham & Women's Hospital, Boston, MA
1984 - 1989NIH Clinical Investigator Award "Vascular smooth muscle cDNA contractile protein clones" Boston Children's Hospital, Boston, MA
1991 - 1995Irma T. Hirschl Award "Isolation and characterization of genes regulating blood vessel growth
1996     Distinguished Research Award, Department of Medicine, Mount Sinai School Of Medicine
2002     Special Recognition Award, Council on Arteriosclerosis, Thrombosis, and Vascular Biology
2004     Alpha Omega Alpha
 
 Overview
Dr. Mark B. Taubman received his BA in Biochemistry from Columbia University and his M.D. from New York University School of Medicine. He subsequently completed a Residency in Internal Medicine and a Fellowship in Cardiovascular Diseases at the Brigham and Women's Hospital of Harvard Medical School. After 5 years on the faculty of the Brigham and Women's Hospital, he joined the Mount Sinai School of Medicine in New York, where he developed a well-funded research program in vascular biology, focusing on the regulation of pro-inflammatory and pro-thrombotic molecules in smooth muscle cells and in the arterial wall. In addition to his research program, Dr. Taubman was the Director of the Cardiology Fellowship, the Principal Investigator of an NIH training grant in Molecular Cardiology, and the Director of the Medical Scientist Training Program (MD-PhD). In 2003, Dr. Taubman moved to the University of Rochester as Chief of the Cardiology Division, and the Director of the Cardiovascular Research Institute. In 2007, Dr. Taubman was appointed Chairman of the Department of Medicine. Dr. Taubman has served as a charter member of the AICS study section of the NHLBI and the Chairman of the Research Committee of the National American Heart Association (AHA). In 2006, in recognition of his contributions to vascular biology, he received the Russell Ross Memorial Award of the Arteriosclerosis, Thrombosis, and Vascular Biology Council of the AHA. In 2007, Dr. Taubman was named Editor-in-Chief of the AHA journal, Arteriosclerosis, Thrombosis, and Vascular Biology.

 
 Selected Publications
  • Rong JX, Blachford C, Feig JE, Bander I, Mayne J, Kusunoki J, Miller C, Davis M, Wilson M, Dehn S, Thorp E, Tabas I, Taubman MB, Rudel LL, Fisher EA. ACAT Inhibition Reduces the Progression of Preexisting, Advanced Atherosclerotic Mouse Lesions Without Plaque or Systemic Toxicity. Arterioscler Thromb Vasc Biol. 2013 Jan; 33(1):4-12.
    View in: PubMed
  • Dhawan L, Liu B, Pytlak A, Kulshrestha S, Blaxall BC, Taubman MB. Y-Box Binding Protein 1 and RNase UK114 Mediate Monocyte Chemoattractant Protein 1 mRNA Stability in Vascular Smooth Muscle Cells. Mol Cell Biol. 2012 Sep; 32(18):3768-75.
    View in: PubMed
  • Stewart JC, Chalupa DC, Devlin RB, Frasier LM, Huang LS, Little EL, Lee SM, Phipps RP, Pietropaoli AP, Taubman MB, Utell MJ, Frampton MW. Vascular effects of ultrafine particles in persons with type 2 diabetes. Environ Health Perspect. 2010 Dec; 118(12):1692-8.
    View in: PubMed
  • Liu B, Dhawan L, Blaxall BC, Taubman MB. Protein kinase Cd mediates MCP-1 mRNA stabilization in vascular smooth muscle cells. Mol Cell Biochem. 2010 Nov; 344(1-2):73-9.
    View in: PubMed
  • Fu J, Taubman MB. Prolyl hydroxylase EGLN3 regulates skeletal myoblast differentiation through an NF-kappaB-dependent pathway. J Biol Chem. 2010 Mar 19; 285(12):8927-35.
    View in: PubMed
  • Spinelli SL, Casey AE, Pollock SJ, Gertz JM, McMillan DH, Narasipura SD, Mody NA, King MR, Maggirwar SB, Francis CW, Taubman MB, Blumberg N, Phipps RP. Platelets and megakaryocytes contain functional nuclear factor-kappaB. Arterioscler Thromb Vasc Biol. 2010 Mar; 30(3):591-8.
    View in: PubMed
  • Mackman N, Taubman M. Tissue factor: past, present, and future. Arterioscler Thromb Vasc Biol. 2009 Dec; 29(12):1986-8.
    View in: PubMed
  • Kasthuri RS, Taubman MB, Mackman N. Role of tissue factor in cancer. J Clin Oncol. 2009 Oct 10; 27(29):4834-8.
    View in: PubMed
  • Bernard JJ, Seweryniak KE, Koniski AD, Spinelli SL, Blumberg N, Francis CW, Taubman MB, Palis J, Phipps RP. Foxp3 regulates megakaryopoiesis and platelet function. Arterioscler Thromb Vasc Biol. 2009 Nov; 29(11):1874-82.
    View in: PubMed
  • Yao JL, Ryan CK, Francis CW, Kohli M, Taubman MB, Khorana AA. Tissue factor and VEGF expression in prostate carcinoma: a tissue microarray study. Cancer Invest. 2009 May; 27(4):430-4.
    View in: PubMed
  • Springer DL, Miller JH, Spinelli SL, Pasa-Tolic L, Purvine SO, Daly DS, Zangar RC, Jin S, Blumberg N, Francis CW, Taubman MB, Casey AE, Wittlin SD, Phipps RP. Platelet proteome changes associated with diabetes and during platelet storage for transfusion. J Proteome Res. 2009 May; 8(5):2261-72.
    View in: PubMed
  • Blumberg N, Spinelli SL, Francis CW, Taubman MB, Phipps RP. The platelet as an immune cell-CD40 ligand and transfusion immunomodulation. Immunol Res. 2009; 45(2-3):251-60.
    View in: PubMed
  • Wang L, Miller C, Swarthout RF, Rao M, Mackman N, Taubman MB. Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury. Blood. 2009 Jan 15; 113(3):705-13.
    View in: PubMed
  • Khorana AA, Francis CW, Menzies KE, Wang JG, Hyrien O, Hathcock J, Mackman N, Taubman MB. Plasma tissue factor may be predictive of venous thromboembolism in pancreatic cancer. J Thromb Haemost. 2008 Nov; 6(11):1983-5.
    View in: PubMed
  • O'Brien JJ, Spinelli SL, Tober J, Blumberg N, Francis CW, Taubman MB, Palis J, Seweryniak KE, Gertz JM, Phipps RP. 15-deoxy-delta12,14-PGJ2 enhances platelet production from megakaryocytes. Blood. 2008 Nov 15; 112(10):4051-60.
    View in: PubMed
  • Alexis JD, Pyo RT, Chereshnev I, Katz J, Rollins BJ, Charo IF, Taubman MB. Inhibition of MCP-1/CCR2 signaling does not inhibit intimal proliferation in a mouse aortic transplant model. J Vasc Res. 2008; 45(6):538-46.
    View in: PubMed
  • Mackman N, Taubman MB. Does tissue factor expression by vascular smooth muscle cells provide a link between C-reactive protein and cardiovascular disease? Arterioscler Thromb Vasc Biol. 2008 Apr; 28(4):601-3.
    View in: PubMed
  • Taubman MB, Wang L, Miller C. The role of smooth muscle derived tissue factor in mediating thrombosis and arterial injury. Thromb Res. 2008; 122 Suppl 1:S78-81.
    View in: PubMed
  • Spinelli SL, O'Brien JJ, Bancos S, Lehmann GM, Springer DL, Blumberg N, Francis CW, Taubman MB, Phipps RP. The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects. PPAR Res. 2008; 2008:328172.
    View in: PubMed
  • Ray DM, Spinelli SL, Pollock SJ, Murant TI, O'Brien JJ, Blumberg N, Francis CW, Taubman MB, Phipps RP. Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles. Thromb Haemost. 2008 Jan; 99(1):86-95.
    View in: PubMed
  • White RJ, Meoli DF, Swarthout RF, Kallop DY, Galaria II, Harvey JL, Miller CM, Blaxall BC, Hall CM, Pierce RA, Cool CD, Taubman MB. Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2007 Sep; 293(3):L583-90.
    View in: PubMed
  • Khorana AA, Ahrendt SA, Ryan CK, Francis CW, Hruban RH, Hu YC, Hostetter G, Harvey J, Taubman MB. Tissue factor expression, angiogenesis, and thrombosis in pancreatic cancer. Clin Cancer Res. 2007 May 15; 13(10):2870-5.
    View in: PubMed
  • Mieszczanska H, Kaba NK, Francis CW, Gerich JE, Dodis R, Schwarz KQ, Phipps RP, Smith BH, Lee M, Messing S, Taubman MB. Effects of pioglitazone on fasting and postprandial levels of lipid and hemostatic variables in overweight non-diabetic patients with coronary artery disease. J Thromb Haemost. 2007 May; 5(5):942-9.
    View in: PubMed
  • Fu J, Menzies K, Freeman RS, Taubman MB. EGLN3 prolyl hydroxylase regulates skeletal muscle differentiation and myogenin protein stability. J Biol Chem. 2007 Apr 27; 282(17):12410-8.
    View in: PubMed
  • Dhawan L, Liu B, Blaxall BC, Taubman MB. A novel role for the glucocorticoid receptor in the regulation of monocyte chemoattractant protein-1 mRNA stability. J Biol Chem. 2007 Apr 6; 282(14):10146-52.
    View in: PubMed
  • O'Brien JJ, Ray DM, Spinelli SL, Blumberg N, Taubman MB, Francis CW, Wittlin SD, Phipps RP. The platelet as a therapeutic target for treating vascular diseases and the role of eicosanoid and synthetic PPARgamma ligands. Prostaglandins Other Lipid Mediat. 2007 Jan; 82(1-4):68-76.
    View in: PubMed
  • Liu B, Poon M, Taubman MB. PDGF-BB enhances monocyte chemoattractant protein-1 mRNA stability in smooth muscle cells by downregulating ribonuclease activity. J Mol Cell Cardiol. 2006 Jul; 41(1):160-9.
    View in: PubMed
  • Bogdanov VY, Kirk RI, Miller C, Hathcock JJ, Vele S, Gazdoiu M, Nemerson Y, Taubman MB. Identification and characterization of murine alternatively spliced tissue factor. J Thromb Haemost. 2006 Jan; 4(1):158-67.
    View in: PubMed
  • White RJ, Galaria II, Harvey J, Blaxall BC, Cool CD, Taubman MB. Tissue factor is induced in a rodent model of severe pulmonary hypertension characterized by neointimal lesions typical of human disease. Chest. 2005 Dec; 128(6 Suppl):612S-613S.
    View in: PubMed
  • Campagnolo L, Leahy A, Chitnis S, Koschnick S, Fitch MJ, Fallon JT, Loskutoff D, Taubman MB, Stuhlmann H. EGFL7 is a chemoattractant for endothelial cells and is up-regulated in angiogenesis and arterial injury. Am J Pathol. 2005 Jul; 167(1):275-84.
    View in: PubMed
  • Charo IF, Taubman MB. Chemokines in the pathogenesis of vascular disease. Circ Res. 2004 Oct 29; 95(9):858-66.
    View in: PubMed
  • Pyo RT, Sato Y, Mackman N, Taubman MB. Mice deficient in tissue factor demonstrate attenuated intimal hyperplasia in response to vascular injury and decreased smooth muscle cell migration. Thromb Haemost. 2004 Sep; 92(3):451-8.
    View in: PubMed
  • Pyo R, Jensen KK, Wiekowski MT, Manfra D, Alcami A, Taubman MB, Lira SA. Inhibition of intimal hyperplasia in transgenic mice conditionally expressing the chemokine-binding protein M3. Am J Pathol. 2004 Jun; 164(6):2289-97.
    View in: PubMed
  • Menzies K, Liu B, Kim WJ, Moschella MC, Taubman MB. Regulation of the SM-20 prolyl hydroxylase gene in smooth muscle cells. Biochem Biophys Res Commun. 2004 May 7; 317(3):801-10.
    View in: PubMed
  • Kodali RB, Kim WJ, Galaria II, Miller C, Schecter AD, Lira SA, Taubman MB. CCL11 (Eotaxin) induces CCR3-dependent smooth muscle cell migration. Arterioscler Thromb Vasc Biol. 2004 Jul; 24(7):1211-6.
    View in: PubMed
  • Schecter AD, Berman AB, Yi L, Ma H, Daly CM, Soejima K, Rollins BJ, Charo IF, Taubman MB. MCP-1-dependent signaling in CCR2(-/-) aortic smooth muscle cells. J Leukoc Biol. 2004 Jun; 75(6):1079-85.
    View in: PubMed
  • Kim WJ, Chereshnev I, Gazdoiu M, Fallon JT, Rollins BJ, Taubman MB. MCP-1 deficiency is associated with reduced intimal hyperplasia after arterial injury. Biochem Biophys Res Commun. 2003 Oct 24; 310(3):936-42.
    View in: PubMed
  • Haque NS, Fallon JT, Pan JJ, Taubman MB, Harpel PC. Chemokine receptor-8 (CCR8) mediates human vascular smooth muscle cell chemotaxis and metalloproteinase-2 secretion. Blood. 2004 Feb 15; 103(4):1296-304.
    View in: PubMed
  • Schecter AD, Berman AB, Taubman MB. Chemokine receptors in vascular smooth muscle. Microcirculation. 2003 Jun; 10(3-4):265-72.
    View in: PubMed
  • Taubman MB. Angiotensin II: a vasoactive hormone with ever-increasing biological roles. Circ Res. 2003 Jan 10; 92(1):9-11.
    View in: PubMed
  • Pawlinski R, Fernandes A, Kehrle B, Pedersen B, Parry G, Erlich J, Pyo R, Gutstein D, Zhang J, Castellino F, Melis E, Carmeliet P, Baretton G, Luther T, Taubman M, Rosen E, Mackman N. Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction. Proc Natl Acad Sci U S A. 2002 Nov 26; 99(24):15333-8.
    View in: PubMed
  • Rong JX, Berman JW, Taubman MB, Fisher EA. Lysophosphatidylcholine stimulates monocyte chemoattractant protein-1 gene expression in rat aortic smooth muscle cells. Arterioscler Thromb Vasc Biol. 2002 Oct 1; 22(10):1617-23.
    View in: PubMed
  • Roque M, Kim WJ, Gazdoin M, Malik A, Reis ED, Fallon JT, Badimon JJ, Charo IF, Taubman MB. CCR2 deficiency decreases intimal hyperplasia after arterial injury. Arterioscler Thromb Vasc Biol. 2002 Apr 1; 22(4):554-9.
    View in: PubMed
  • Lieb ME, Menzies K, Moschella MC, Ni R, Taubman MB. Mammalian EGLN genes have distinct patterns of mRNA expression and regulation. Biochem Cell Biol. 2002; 80(4):421-6.
    View in: PubMed
  • Schecter AD, Berman AB, Yi L, Mosoian A, McManus CM, Berman JW, Klotman ME, Taubman MB. HIV envelope gp120 activates human arterial smooth muscle cells. Proc Natl Acad Sci U S A. 2001 Aug 28; 98(18):10142-7.
    View in: PubMed
  • Roqué M, Reis ED, Cordon-Cardo C, Taubman MB, Fallon JT, Fuster V, Badimon JJ. Effect of p27 deficiency and rapamycin on intimal hyperplasia: in vivo and in vitro studies using a p27 knockout mouse model. Lab Invest. 2001 Jun; 81(6):895-903.
    View in: PubMed
  • Poon M, Gertz SD, Fallon JT, Wiegman P, Berman JW, Sarembock IJ, Taubman MB. Dexamethasone inhibits macrophage accumulation after balloon arterial injury in cholesterol fed rabbits. Atherosclerosis. 2001 Apr; 155(2):371-80.
    View in: PubMed
  • Holness W, Santore TA, Brown GP, Fallon JT, Taubman MB, Iyengar R. Expression of Q227L-Galpha(s) inhibits intimal vessel wall hyperplasia after balloon injury. Proc Natl Acad Sci U S A. 2001 Jan 30; 98(3):1288-93.
    View in: PubMed
  • Haque NS, Fallon JT, Taubman MB, Harpel PC. The chemokine receptor CCR8 mediates human endothelial cell chemotaxis induced by I-309 and Kaposi sarcoma herpesvirus-encoded vMIP-I and by lipoprotein(a)-stimulated endothelial cell conditioned medium. Blood. 2001 Jan 1; 97(1):39-45.
    View in: PubMed
  • Roqué M, Reis ED, Fuster V, Padurean A, Fallon JT, Taubman MB, Chesebro JH, Badimon JJ. Inhibition of tissue factor reduces thrombus formation and intimal hyperplasia after porcine coronary angioplasty. J Am Coll Cardiol. 2000 Dec; 36(7):2303-10.
    View in: PubMed
  • Weintraub AS, Schnapp LM, Lin X, Taubman MB. Osteopontin deficiency in rat vascular smooth muscle cells is associated with an inability to adhere to collagen and increased apoptosis. Lab Invest. 2000 Nov; 80(11):1603-15.
    View in: PubMed
  • Haque NS, Zhang X, French DL, Li J, Poon M, Fallon JT, Gabel BR, Taubman MB, Koschinsky M, Harpel PC. CC chemokine I-309 is the principal monocyte chemoattractant induced by apolipoprotein(a) in human vascular endothelial cells. Circulation. 2000 Aug 15; 102(7):786-92.
    View in: PubMed
  • Schecter AD, Spirn B, Rossikhina M, Giesen PL, Bogdanov V, Fallon JT, Fisher EA, Schnapp LM, Nemerson Y, Taubman MB. Release of active tissue factor by human arterial smooth muscle cells. Circ Res. 2000 Jul 21; 87(2):126-32.
    View in: PubMed
  • Calderon TM, Gertz SD, Sarembock IJ, Berliner JA, Fallon JT, Taubman MB, Berman JW. Induction of IG9 monocyte adhesion molecule expression in smooth muscle and endothelial cells after balloon arterial injury in cholesterol-fed rabbits. Arterioscler Thromb Vasc Biol. 2000 May; 20(5):1293-300.
    View in: PubMed
  • Giesen PL, Fyfe BS, Fallon JT, Roque M, Mendlowitz M, Rossikhina M, Guha A, Badimon JJ, Nemerson Y, Taubman MB. Intimal tissue factor activity is released from the arterial wall after injury. Thromb Haemost. 2000 Apr; 83(4):622-8.
    View in: PubMed
  • Schecter AD, Calderon TM, Berman AB, McManus CM, Fallon JT, Rossikhina M, Zhao W, Christ G, Berman JW, Taubman MB. Human vascular smooth muscle cells possess functional CCR5. J Biol Chem. 2000 Feb 25; 275(8):5466-71.
    View in: PubMed
  • Roque M, Fallon JT, Badimon JJ, Zhang WX, Taubman MB, Reis ED. Mouse model of femoral artery denudation injury associated with the rapid accumulation of adhesion molecules on the luminal surface and recruitment of neutrophils. Arterioscler Thromb Vasc Biol. 2000 Feb; 20(2):335-42.
    View in: PubMed
  • Hirshfeld JW, Banas JS, Brundage BH, Cowley M, Dehmer GJ, Ellis SG, Ewy GA, Faxon DP, Holmes DR, Jacobs AK, Little WC, Magorien RD, Nocero MA, Oesterle S, Pepine CJ, Taubman M, Tommaso C, Vlietstra RE, Vogel R, Forrester JS, Douglas PS, Faxon DP, Fischer JD, Gregoratos G, Wolk MJ, et al. American College of Cardiology training statement on recommendations for the structure of an optimal adult interventional cardiology training program: a report of the American College of Cardiology task force on clinical expert consensus documents. J Am Coll Cardiol. 1999 Dec; 34(7):2141-7.
    View in: PubMed
  • Poon M, Cohen J, Siddiqui Z, Fallon JT, Taubman MB. Trapidil inhibits monocyte chemoattractant protein-1 and macrophage accumulation after balloon arterial injury in rabbits. Lab Invest. 1999 Nov; 79(11):1369-75.
    View in: PubMed
  • Poon M, Liu B, Taubman MB. Identification of a novel dexamethasone-sensitive RNA-destabilizing region on rat monocyte chemoattractant protein 1 mRNA. Mol Cell Biol. 1999 Oct; 19(10):6471-8.
    View in: PubMed
  • Aikawa M, Voglic SJ, Sugiyama S, Rabkin E, Taubman MB, Fallon JT, Libby P. Dietary lipid lowering reduces tissue factor expression in rabbit atheroma. Circulation. 1999 Sep 14; 100(11):1215-22.
    View in: PubMed
  • Taubman MB, Giesen PL, Schecter AD, Nemerson Y. Regulation of the procoagulant response to arterial injury. Thromb Haemost. 1999 Aug; 82(2):801-5.
    View in: PubMed
  • Camera M, Giesen PL, Fallon J, Aufiero BM, Taubman M, Tremoli E, Nemerson Y. Cooperation between VEGF and TNF-alpha is necessary for exposure of active tissue factor on the surface of human endothelial cells. Arterioscler Thromb Vasc Biol. 1999 Mar; 19(3):531-7.
    View in: PubMed
  • Moschella MC, Menzies K, Tsao L, Lieb MA, Kohtz JD, Kohtz DS, Taubman MB. SM-20 is a novel growth factor-responsive gene regulated during skeletal muscle development and differentiation. Gene Expr. 1999; 8(1):59-66.
    View in: PubMed
  • Lieb ME, Taubman MB. Preparation of cDNA libraries from vascular cells. Methods Mol Med. 1999; 30:47-57.
    View in: PubMed
  • Bogdanov VY, Poon M, Taubman MB. Platelet-derived growth factor-specific regulation of the JE promoter in rat aortic smooth muscle cells. J Biol Chem. 1998 Sep 18; 273(38):24932-8.
    View in: PubMed
  • Gertz SD, Fallon JT, Gallo R, Taubman MB, Banai S, Barry WL, Gimple LW, Nemerson Y, Thiruvikraman S, Naidu SS, Chesebro JH, Fuster V, Sarembock IJ, Badimon JJ. Hirudin reduces tissue factor expression in neointima after balloon injury in rabbit femoral and porcine coronary arteries. Circulation. 1998 Aug 11; 98(6):580-7.
    View in: PubMed
  • Hall CL, Taubman MB, Nemerson Y, Turitto VT. Factor Xa generation at the surface of cultured rat vascular smooth muscle cells in an in vitro flow system. J Biomech Eng. 1998 Aug; 120(4):484-90.
    View in: PubMed
  • Schecter AD, Rollins BJ, Zhang YJ, Charo IF, Fallon JT, Rossikhina M, Giesen PL, Nemerson Y, Taubman MB. Tissue factor is induced by monocyte chemoattractant protein-1 in human aortic smooth muscle and THP-1 cells. J Biol Chem. 1997 Nov 7; 272(45):28568-73.
    View in: PubMed
  • Poon M, Zhang X, Dunsky K, Taubman MB, Harpel PC. Apolipoprotein(a) is a human vascular endothelial cell agonist: studies on the induction in endothelial cells of monocyte chemotactic factor activity. Clin Genet. 1997 Nov; 52(5):308-13.
    View in: PubMed
  • Schecter AD, Giesen PL, Taby O, Rosenfield CL, Rossikhina M, Fyfe BS, Kohtz DS, Fallon JT, Nemerson Y, Taubman MB. Tissue factor expression in human arterial smooth muscle cells. TF is present in three cellular pools after growth factor stimulation. J Clin Invest. 1997 Nov 1; 100(9):2276-85.
    View in: PubMed
  • Poon M, Zhang X, Dunsky KG, Taubman MB, Harpel PC. Apolipoprotein(a) induces monocyte chemotactic activity in human vascular endothelial cells. Circulation. 1997 Oct 21; 96(8):2514-9.
    View in: PubMed
  • Taubman MB, Fallon JT, Schecter AD, Giesen P, Mendlowitz M, Fyfe BS, Marmur JD, Nemerson Y. Tissue factor in the pathogenesis of atherosclerosis. Thromb Haemost. 1997 Jul; 78(1):200-4.
    View in: PubMed
  • Poon M, Marx SO, Gallo R, Badimon JJ, Taubman MB, Marks AR. Rapamycin inhibits vascular smooth muscle cell migration. J Clin Invest. 1996 Nov 15; 98(10):2277-83.
    View in: PubMed
  • Taby O, Rosenfield CL, Bogdanov V, Nemerson Y, Taubman MB. Cloning of the rat tissue factor cDNA and promoter: identification of a serum-response region. Thromb Haemost. 1996 Nov; 76(5):697-702.
    View in: PubMed
  • Thiruvikraman SV, Guha A, Roboz J, Taubman MB, Nemerson Y, Fallon JT. In situ localization of tissue factor in human atherosclerotic plaques by binding of digoxigenin-labeled factors VIIa and X. Lab Invest. 1996 Oct; 75(4):451-61.
    View in: PubMed
  • Marmur JD, Thiruvikraman SV, Fyfe BS, Guha A, Sharma SK, Ambrose JA, Fallon JT, Nemerson Y, Taubman MB. Identification of active tissue factor in human coronary atheroma. Circulation. 1996 Sep 15; 94(6):1226-32.
    View in: PubMed
  • Weintraub AS, Giachelli CM, Krauss RS, Almeida M, Taubman MB. Autocrine secretion of osteopontin by vascular smooth muscle cells regulates their adhesion to collagen gels. Am J Pathol. 1996 Jul; 149(1):259-72.
    View in: PubMed
  • Poon M, Hsu WC, Bogdanov VY, Taubman MB. Secretion of monocyte chemotactic activity by cultured rat aortic smooth muscle cells in response to PDGF is due predominantly to the induction of JE/MCP-1. Am J Pathol. 1996 Jul; 149(1):307-17.
    View in: PubMed
  • Wax SD, Tsao L, Lieb ME, Fallon JT, Taubman MB. SM-20 is a novel 40-kd protein whose expression in the arterial wall is restricted to smooth muscle. Lab Invest. 1996 Apr; 74(4):797-808.
    View in: PubMed
  • Harpel PC, Poon M, Zhang X, Taubman MB. Lipoprotein(a): searching for a function. Trans Am Clin Climatol Assoc. 1996; 107:125-33.
    View in: PubMed
  • Green RS, Lieb ME, Weintraub AS, Gacheru SN, Rosenfield CL, Shah S, Kagan HM, Taubman MB. Identification of lysyl oxidase and other platelet-derived growth factor-inducible genes in vascular smooth muscle cells by differential screening. Lab Invest. 1995 Oct; 73(4):476-82.
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  • Patton WF, Erdjument-Bromage H, Marks AR, Tempst P, Taubman MB. Components of the protein synthesis and folding machinery are induced in vascular smooth muscle cells by hypertrophic and hyperplastic agents. Identification by comparative protein phenotyping and microsequencing. J Biol Chem. 1995 Sep 8; 270(36):21404-10.
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  • Wax SD, Rosenfield CL, Taubman MB. Identification of a novel growth factor-responsive gene in vascular smooth muscle cells. J Biol Chem. 1994 Apr 29; 269(17):13041-7.
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  • Applegate D, Feng W, Green RS, Taubman MB. Cloning and expression of a novel acidic calponin isoform from rat aortic vascular smooth muscle. J Biol Chem. 1994 Apr 8; 269(14):10683-90.
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  • Taubman MB. Tissue factor regulation in vascular smooth muscle: a summary of studies performed using in vivo and in vitro models. Am J Cardiol. 1993 Sep 9; 72(8):55C-60C.
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  • Taubman MB. Gene induction in vessel wall injury. Thromb Haemost. 1993 Jul 1; 70(1):180-3.
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  • Marmur JD, Rossikhina M, Guha A, Fyfe B, Friedrich V, Mendlowitz M, Nemerson Y, Taubman MB. Tissue factor is rapidly induced in arterial smooth muscle after balloon injury. J Clin Invest. 1993 May; 91(5):2253-9.
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  • Taubman MB, Marmur JD, Rosenfield CL, Guha A, Nichtberger S, Nemerson Y. Agonist-mediated tissue factor expression in cultured vascular smooth muscle cells. Role of Ca2+ mobilization and protein kinase C activation. J Clin Invest. 1993 Feb; 91(2):547-52.
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  • Rothman A, Kulik TJ, Taubman MB, Berk BC, Smith CW, Nadal-Ginard B. Development and characterization of a cloned rat pulmonary arterial smooth muscle cell line that maintains differentiated properties through multiple subcultures. Circulation. 1992 Dec; 86(6):1977-86.
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  • Marmur JD, Poon M, Rossikhina M, Taubman MB. Induction of PDGF-responsive genes in vascular smooth muscle. Implications for the early response to vessel injury. Circulation. 1992 Dec; 86(6 Suppl):III53-60.
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  • Taubman MB, Rollins BJ, Poon M, Marmur J, Green RS, Berk BC, Nadal-Ginard B. JE mRNA accumulates rapidly in aortic injury and in platelet-derived growth factor-stimulated vascular smooth muscle cells. Circ Res. 1992 Feb; 70(2):314-25.
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  • Safirstein R, Megyesi J, Saggi SJ, Price PM, Poon M, Rollins BJ, Taubman MB. Expression of cytokine-like genes JE and KC is increased during renal ischemia. Am J Physiol. 1991 Dec; 261(6 Pt 2):F1095-101.
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  • Poon M, Megyesi J, Green RS, Zhang H, Rollins BJ, Safirstein R, Taubman MB. In vivo and in vitro inhibition of JE gene expression by glucocorticoids. J Biol Chem. 1991 Nov 25; 266(33):22375-9.
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  • Griendling KK, Taubman MB, Akers M, Mendlowitz M, Alexander RW. Characterization of phosphatidylinositol-specific phospholipase C from cultured vascular smooth muscle cells. J Biol Chem. 1991 Aug 15; 266(23):15498-504.
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  • Marks AR, Taubman MB, Saito A, Dai Y, Fleischer S. The ryanodine receptor/junctional channel complex is regulated by growth factors in a myogenic cell line. J Cell Biol. 1991 Jul; 114(2):303-12.
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  • Berk BC, Taubman MB, Griendling KK, Cragoe EJ, Fenton JW, Brock TA. Thrombin-stimulated events in cultured vascular smooth-muscle cells. Biochem J. 1991 Mar 15; 274 ( Pt 3):799-805.
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  • Berk BC, Taubman MB, Cragoe EJ, Fenton JW, Griendling KK. Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. Calcium and protein kinase C-dependent and -independent pathways. J Biol Chem. 1990 Oct 5; 265(28):17334-40.
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  • Grant JW, Taubman MB, Church SL, Johnson RL, Nadal-Ginard B. Mammalian nonsarcomeric myosin regulatory light chains are encoded by two differentially regulated and linked genes. J Cell Biol. 1990 Sep; 111(3):1127-35.
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  • Ip JH, Fuster V, Badimon L, Badimon J, Taubman MB, Chesebro JH. Syndromes of accelerated atherosclerosis: role of vascular injury and smooth muscle cell proliferation. J Am Coll Cardiol. 1990 Jun; 15(7):1667-87.
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  • Marks AR, Tempst P, Hwang KS, Taubman MB, Inui M, Chadwick C, Fleischer S, Nadal-Ginard B. Molecular cloning and characterization of the ryanodine receptor/junctional channel complex cDNA from skeletal muscle sarcoplasmic reticulum. Proc Natl Acad Sci U S A. 1989 Nov; 86(22):8683-7.
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  • Taubman MB, Smith CW, Izumo S, Grant JW, Endo T, Andreadis A, Nadal-Ginard B. The expression of sarcomeric muscle-specific contractile protein genes in BC3H1 cells: BC3H1 cells resemble skeletal myoblasts that are defective for commitment to terminal differentiation. J Cell Biol. 1989 May; 108(5):1799-806.
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  • Taubman MB, Berk BC, Izumo S, Tsuda T, Alexander RW, Nadal-Ginard B. Angiotensin II induces c-fos mRNA in aortic smooth muscle. Role of Ca2+ mobilization and protein kinase C activation. J Biol Chem. 1989 Jan 5; 264(1):526-30.
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  • Taubman MB, Grant JW, Nadal-Ginard B. Cloning and characterization of mammalian myosin regulatory light chain (RLC) cDNA: the RLC gene is expressed in smooth, sarcomeric, and nonmuscle tissues. J Cell Biol. 1987 Jun; 104(6):1505-13.
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  • Goldberg BD, Phelps RG, Kessler E, Klein MJ, Taubman MB. The carboxyl fragment released by bacterial collagenase from human type I procollagen: antibodies to the propeptide determinants. Coll Relat Res. 1985 Nov; 5(5):393-404.
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  • Berk BC, Brock TA, Webb RC, Taubman MB, Atkinson WJ, Gimbrone MA, Alexander RW. Epidermal growth factor, a vascular smooth muscle mitogen, induces rat aortic contraction. J Clin Invest. 1985 Mar; 75(3):1083-6.
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  • Taubman MB, Goldberg B. Antigenic relatedness of primate procollagens as determined by a competitive radioimmunoassay. Comp Biochem Physiol B. 1978; 59(1):47-9.
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  • Taubman MB, Kammerman S, Goldberg B. Radioimmunoassay of procollagen in serum of patients with Paget's disease of bone. Proc Soc Exp Biol Med. 1976 Jun; 152(2):284-7.
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  • Taubman MB, Goldberg B. The processing of procollagen in cultures of human and mouse fibroblasts. Arch Biochem Biophys. 1976 Apr; 173(2):490-4.
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  • Goldberg B, Taubman MB, Radin A. Procollagen peptidase: its mode of action on the native substrate. Cell. 1975 Jan; 4(1):45-50.
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  • Taubman MB, Goldberg B, Sherr C. Radioimmunoassay for human procollagen. Science. 1974 Dec 20; 186(4169):1115-7.
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  • Sherr CJ, Taubman MB, Goldberg B. Isolation of a disulfide-stabilized, three-chain polypeptide fragment unique to the precursor of human collagen. J Biol Chem. 1973 Oct 25; 248(20):7033-8.
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