Timothy Bushnell
| Title | Assistant Professor |
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| Institution | School of Medicine and Dentistry |
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| Department | Pediatrics in the Center for Pediatric Biomedical Research |
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| Address | University of Rochester Medical Center School of Medicine and Dentistry 601 Elmwood Ave, Box 703 Rochester NY 14642
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| Title | Director, Core Operations |
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| Institution | School of Medicine and Dentistry |
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| Department | Dean's Office M&D - Administration |
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| Title | Assistant Professor |
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| Institution | University of Rochester Medical Center |
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| Department | Cancer Center |
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| 1983 |
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| Eagle Scout | | 1995 |
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| American Society of Microbiology Student Travel Grant Award | | 1995 |
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| Young Investigator Award | | 1996 |
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| American Society of Microbiology Student Travel Grant Award |
My main research focus is the development and application of high-end flow cytometric assays to support the research programs of members of the URMC community.
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Kingsley PD, Greenfest-Allen E, Frame JM, Bushnell TP, Malik J, McGrath KE, Stoeckert CJ, Palis J. Ontogeny of erythroid gene expression. Blood. 2013 Feb 7; 121(6):e5-e13.
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Williams MA, Bauer S, Lu W, Guo J, Walter S, Bushnell TP, Lillehoj EP, Georas SN. Deletion of the mucin-like molecule muc1 enhances dendritic cell activation in response to toll-like receptor ligands. J Innate Immun. 2010; 2(2):123-43.
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Palapattu GS, Wu C, Silvers CR, Martin HB, Williams K, Salamone L, Bushnell T, Huang LS, Yang Q, Huang J. Selective expression of CD44, a putative prostate cancer stem cell marker, in neuroendocrine tumor cells of human prostate cancer. Prostate. 2009 May 15; 69(7):787-98.
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Teodori L, Bushnell T, Campanella L, Tárnok A. GFP: from humble beginnings to Nobel winnings--the color that changed cytometry. Cytometry A. 2008 Dec; 73A(12):1109-10.
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Wang PY, Young F, Chen CY, Stevens BM, Neering SJ, Rossi RM, Bushnell T, Kuzin I, Heinrich D, Bottaro A, Jordan CT. The biologic properties of leukemias arising from BCR/ABL-mediated transformation vary as a function of developmental origin and activity of the p19ARF gene. Blood. 2008 Nov 15; 112(10):4184-92.
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McGrath KE, Bushnell TP, Palis J. Multispectral imaging of hematopoietic cells: where flow meets morphology. J Immunol Methods. 2008 Jul 31; 336(2):91-7.
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Enos ME, Bancos SA, Bushnell T, Crispe IN. E2F4 modulates differentiation and gene expression in hematopoietic progenitor cells during commitment to the lymphoid lineage. J Immunol. 2008 Mar 15; 180(6):3699-707.
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McGrath KE, Kingsley PD, Koniski AD, Porter RL, Bushnell TP, Palis J. Enucleation of primitive erythroid cells generates a transient population of "pyrenocytes" in the mammalian fetus. Blood. 2008 Feb 15; 111(4):2409-17.
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Guzman ML, Li X, Corbett CA, Rossi RM, Bushnell T, Liesveld JL, Hébert J, Young F, Jordan CT. Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8). Blood. 2007 Dec 15; 110(13):4436-44.
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Graf B, Bushnell T, Miller J. LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the central supramolecular activation cluster and exclusion of CD45 from the immunological synapse. J Immunol. 2007 Aug 1; 179(3):1616-24.
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Ryan EP, Bushnell TP, Friedman AE, Rahman I, Phipps RP. Cyclooxygenase-2 independent effects of cyclooxygenase-2 inhibitors on oxidative stress and intracellular glutathione content in normal and malignant human B-cells. Cancer Immunol Immunother. 2008 Mar; 57(3):347-58.
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Neff-LaFord H, Teske S, Bushnell TP, Lawrence BP. Aryl hydrocarbon receptor activation during influenza virus infection unveils a novel pathway of IFN-gamma production by phagocytic cells. J Immunol. 2007 Jul 1; 179(1):247-55.
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Neering SJ, Bushnell T, Sozer S, Ashton J, Rossi RM, Wang PY, Bell DR, Heinrich D, Bottaro A, Jordan CT. Leukemia stem cells in a genetically defined murine model of blast-crisis CML. Blood. 2007 Oct 1; 110(7):2578-85.
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Kingsley PD, Malik J, Emerson RL, Bushnell TP, McGrath KE, Bloedorn LA, Bulger M, Palis J. "Maturational" globin switching in primary primitive erythroid cells. Blood. 2006 Feb 15; 107(4):1665-72.
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Xing L, Bushnell TP, Carlson L, Tai Z, Tondravi M, Siebenlist U, Young F, Boyce BF. NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis. J Bone Miner Res. 2002 Jul; 17(7):1200-10.
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Kuzin II, Snyder JE, Ugine GD, Wu D, Lee S, Bushnell T, Insel RA, Young FM, Bottaro A. Tetracyclines inhibit activated B cell function. Int Immunol. 2001 Jul; 13(7):921-31.
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