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Timothy Bushnell

TitleAssistant Professor
InstitutionSchool of Medicine and Dentistry
DepartmentPediatrics in the Center for Pediatric Biomedical Research
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 703
Rochester NY 14642
Other Positions
TitleDirector, Core Operations
InstitutionSchool of Medicine and Dentistry
DepartmentDean's Office M&D - Administration

TitleAssistant Professor
InstitutionUniversity of Rochester Medical Center
DepartmentCancer Center

 
 Name Suffix
Jr.

 
 Awards And Honors
1983     Eagle Scout
1995     American Society of Microbiology Student Travel Grant Award
1995     Young Investigator Award
1996     American Society of Microbiology Student Travel Grant Award
 
 Overview
My main research focus is the development and application of high-end flow cytometric assays to support the research programs of members of the URMC community.

 
 Selected Publications
  • Kingsley PD, Greenfest-Allen E, Frame JM, Bushnell TP, Malik J, McGrath KE, Stoeckert CJ, Palis J. Ontogeny of erythroid gene expression. Blood. 2013 Feb 7; 121(6):e5-e13.
    View in: PubMed
  • Williams MA, Bauer S, Lu W, Guo J, Walter S, Bushnell TP, Lillehoj EP, Georas SN. Deletion of the mucin-like molecule muc1 enhances dendritic cell activation in response to toll-like receptor ligands. J Innate Immun. 2010; 2(2):123-43.
    View in: PubMed
  • Palapattu GS, Wu C, Silvers CR, Martin HB, Williams K, Salamone L, Bushnell T, Huang LS, Yang Q, Huang J. Selective expression of CD44, a putative prostate cancer stem cell marker, in neuroendocrine tumor cells of human prostate cancer. Prostate. 2009 May 15; 69(7):787-98.
    View in: PubMed
  • Teodori L, Bushnell T, Campanella L, Tárnok A. GFP: from humble beginnings to Nobel winnings--the color that changed cytometry. Cytometry A. 2008 Dec; 73A(12):1109-10.
    View in: PubMed
  • Wang PY, Young F, Chen CY, Stevens BM, Neering SJ, Rossi RM, Bushnell T, Kuzin I, Heinrich D, Bottaro A, Jordan CT. The biologic properties of leukemias arising from BCR/ABL-mediated transformation vary as a function of developmental origin and activity of the p19ARF gene. Blood. 2008 Nov 15; 112(10):4184-92.
    View in: PubMed
  • McGrath KE, Bushnell TP, Palis J. Multispectral imaging of hematopoietic cells: where flow meets morphology. J Immunol Methods. 2008 Jul 31; 336(2):91-7.
    View in: PubMed
  • Enos ME, Bancos SA, Bushnell T, Crispe IN. E2F4 modulates differentiation and gene expression in hematopoietic progenitor cells during commitment to the lymphoid lineage. J Immunol. 2008 Mar 15; 180(6):3699-707.
    View in: PubMed
  • McGrath KE, Kingsley PD, Koniski AD, Porter RL, Bushnell TP, Palis J. Enucleation of primitive erythroid cells generates a transient population of "pyrenocytes" in the mammalian fetus. Blood. 2008 Feb 15; 111(4):2409-17.
    View in: PubMed
  • Guzman ML, Li X, Corbett CA, Rossi RM, Bushnell T, Liesveld JL, Hébert J, Young F, Jordan CT. Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8). Blood. 2007 Dec 15; 110(13):4436-44.
    View in: PubMed
  • Graf B, Bushnell T, Miller J. LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the central supramolecular activation cluster and exclusion of CD45 from the immunological synapse. J Immunol. 2007 Aug 1; 179(3):1616-24.
    View in: PubMed
  • Ryan EP, Bushnell TP, Friedman AE, Rahman I, Phipps RP. Cyclooxygenase-2 independent effects of cyclooxygenase-2 inhibitors on oxidative stress and intracellular glutathione content in normal and malignant human B-cells. Cancer Immunol Immunother. 2008 Mar; 57(3):347-58.
    View in: PubMed
  • Neff-LaFord H, Teske S, Bushnell TP, Lawrence BP. Aryl hydrocarbon receptor activation during influenza virus infection unveils a novel pathway of IFN-gamma production by phagocytic cells. J Immunol. 2007 Jul 1; 179(1):247-55.
    View in: PubMed
  • Neering SJ, Bushnell T, Sozer S, Ashton J, Rossi RM, Wang PY, Bell DR, Heinrich D, Bottaro A, Jordan CT. Leukemia stem cells in a genetically defined murine model of blast-crisis CML. Blood. 2007 Oct 1; 110(7):2578-85.
    View in: PubMed
  • Kingsley PD, Malik J, Emerson RL, Bushnell TP, McGrath KE, Bloedorn LA, Bulger M, Palis J. "Maturational" globin switching in primary primitive erythroid cells. Blood. 2006 Feb 15; 107(4):1665-72.
    View in: PubMed
  • Xing L, Bushnell TP, Carlson L, Tai Z, Tondravi M, Siebenlist U, Young F, Boyce BF. NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis. J Bone Miner Res. 2002 Jul; 17(7):1200-10.
    View in: PubMed
  • Kuzin II, Snyder JE, Ugine GD, Wu D, Lee S, Bushnell T, Insel RA, Young FM, Bottaro A. Tetracyclines inhibit activated B cell function. Int Immunol. 2001 Jul; 13(7):921-31.
    View in: PubMed

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