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Soumya Mitra

TitleResearch Assistant Professor
InstitutionSchool of Medicine and Dentistry
DepartmentImaging Sciences
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 648
Rochester NY 14642
 
 Awards And Honors
2001     Graduate Student Society Merit Award, Awarded by the Graduate student society, University of Rochester Medical Center, Rochester, NY
2002     Gordon Research Conference on Lasers in Medicine and Biology, Poster Presenter
2004     Dean's Award for Outstanding Ph.D. Thesis, University of Rochester School of Medicine and Dentistry, Rochester, NY
 
 Overview
Soumya Mitra received his B.Sc. (1993) and M.Sc. (1995) in Physics from the University of Delhi, India. He came to the University of Rochester in 1997 and received his Ph.D. in Biophysics in 2004. Following that he joined the faculty at the University of Rochester as an Instructor in Radiology in 2004. He was promoted to Research Assistant Professor in 2006.

 
 Selected Publications
List All   |   Timeline
  1. Mitra S, Modi KD, Foster TH. Enzyme-activatable imaging probe reveals enhanced neutrophil elastase activity in tumors following photodynamic therapy. J Biomed Opt. 2013 Oct; 18(10):101314.
    View in: PubMed
  2. Baran TM, Wilson JD, Mitra S, Yao JL, Messing EM, Waldman DL, Foster TH. Optical property measurements establish the feasibility of photodynamic therapy as a minimally invasive intervention for tumors of the kidney. J Biomed Opt. 2012 Sep 28; 17(9):98002-1.
    View in: PubMed
  3. Mitra S, Mironov O, Foster TH. Confocal fluorescence imaging enables noninvasive quantitative assessment of host cell populations in vivo following photodynamic therapy. Theranostics. 2012; 2(9):840-9.
    View in: PubMed
  4. Mitra S, Giesselman BR, De Jesús-Andino FJ, Foster TH. Tumor response to mTHPC-mediated photodynamic therapy exhibits strong correlation with extracellular release of HSP70. Lasers Surg Med. 2011 Sep; 43(7):632-43.
    View in: PubMed
  5. Mitra S, Haidaris CG, Snell SB, Giesselman BR, Hupcher SM, Foster TH. Effective photosensitization and selectivity in vivo of Candida Albicans by meso-tetra (N-methyl-4-pyridyl) porphine tetra tosylate. Lasers Surg Med. 2011 Apr; 43(4):324-32.
    View in: PubMed
  6. Garrier J, Bressenot A, Gräfe S, Marchal S, Mitra S, Foster TH, Guillemin F, Bezdetnaya L. Compartmental targeting for mTHPC-based photodynamic treatment in vivo: Correlation of efficiency, pharmacokinetics, and regional distribution of apoptosis. Int J Radiat Oncol Biol Phys. 2010 Oct 1; 78(2):563-71.
    View in: PubMed
  7. Foster TH, Giesselman BR, Hu R, Kenney ME, Mitra S. Intratumor administration of the photosensitizer pc 4 affords photodynamic therapy efficacy and selectivity at short drug-light intervals. Transl Oncol. 2010 Apr; 3(2):135-41.
    View in: PubMed
  8. Chabrier-Roselló Y, Giesselman BR, De Jesús-Andino FJ, Foster TH, Mitra S, Haidaris CG. Inhibition of electron transport chain assembly and function promotes photodynamic killing of Candida. J Photochem Photobiol B. 2010 Jun 1; 99(3):117-25.
    View in: PubMed
  9. Mitra S, Dolan K, Foster TH, Wellington M. Imaging morphogenesis of Candida albicans during infection in a live animal. J Biomed Opt. 2010 Jan-Feb; 15(1):010504.
    View in: PubMed
  10. Wang KK, Cottrell WJ, Mitra S, Oseroff AR, Foster TH. Simulations of measured photobleaching kinetics in human basal cell carcinomas suggest blood flow reductions during ALA-PDT. Lasers Surg Med. 2009 Nov; 41(9):686-96.
    View in: PubMed
  11. Cummings RJ, Mitra S, Foster TH, Lord EM. Migration of skin dendritic cells in response to ionizing radiation exposure. Radiat Res. 2009 Jun; 171(6):687-97.
    View in: PubMed
  12. Klein MI, Duarte S, Xiao J, Mitra S, Foster TH, Koo H. Structural and molecular basis of the role of starch and sucrose in Streptococcus mutans biofilm development. Appl Environ Microbiol. 2009 Feb; 75(3):837-41.
    View in: PubMed
  13. Wang KK, Mitra S, Foster TH. Photodynamic dose does not correlate with long-term tumor response to mTHPC-PDT performed at several drug-light intervals. Med Phys. 2008 Aug; 35(8):3518-26.
    View in: PubMed
  14. Cummings RJ, Mitra S, Lord EM, Foster TH. Antibody-labeled fluorescence imaging of dendritic cell populations in vivo. J Biomed Opt. 2008 Jul-Aug; 13(4):044041.
    View in: PubMed
  15. Mitra S, Foster TH. In vivo confocal fluorescence imaging of the intratumor distribution of the photosensitizer mono-L-aspartylchlorin-e6. Neoplasia. 2008 May; 10(5):429-38.
    View in: PubMed
  16. Chabrier-Roselló Y, Foster TH, Mitra S, Haidaris CG. Respiratory deficiency enhances the sensitivity of the pathogenic fungus Candida to photodynamic treatment. Photochem Photobiol. 2008 Sep-Oct; 84(5):1141-8.
    View in: PubMed
  17. Wilson JD, Giesselman BR, Mitra S, Foster TH. Lysosome-damage-induced scattering changes coincide with release of cytochrome c. Opt Lett. 2007 Sep 1; 32(17):2517-9.
    View in: PubMed
  18. Wang KK, Wilson JD, Kenney ME, Mitra S, Foster TH. Irradiation-induced enhancement of Pc 4 fluorescence and changes in light scattering are potential dosimeters for Pc 4-PDT. Photochem Photobiol. 2007 Sep-Oct; 83(5):1056-62.
    View in: PubMed
  19. Santos K, Simon DA, Conway E, Bowers WJ, Mitra S, Foster TH, Lugade A, Lord EM, Federoff HJ, Dewhurst S, Frelinger JG. Spatial and temporal expression of herpes simplex virus type 1 amplicon-encoded genes: implications for their use as immunization vectors. Hum Gene Ther. 2007 Feb; 18(2):93-105.
    View in: PubMed
  20. Wang KK, Mitra S, Foster TH. A comprehensive mathematical model of microscopic dose deposition in photodynamic therapy. Med Phys. 2007 Jan; 34(1):282-93.
    View in: PubMed
  21. Mitra S, Cassar SE, Niles DJ, Puskas JA, Frelinger JG, Foster TH. Photodynamic therapy mediates the oxygen-independent activation of hypoxia-inducible factor 1alpha. Mol Cancer Ther. 2006 Dec; 5(12):3268-74.
    View in: PubMed
  22. Foster TH, Pearson BD, Mitra S, Bigelow CE. Fluorescence anisotropy imaging reveals localization of meso-tetrahydroxyphenyl chlorin in the nuclear envelope. Photochem Photobiol. 2005 Nov-Dec; 81(6):1544-7.
    View in: PubMed
  23. Chabrier-Roselló Y, Foster TH, Pérez-Nazario N, Mitra S, Haidaris CG. Sensitivity of Candida albicans germ tubes and biofilms to photofrin-mediated phototoxicity. Antimicrob Agents Chemother. 2005 Oct; 49(10):4288-95.
    View in: PubMed
  24. Mitra S, Maugain E, Bolotine L, Guillemin F, Foster TH. Temporally and spatially heterogeneous distribution of mTHPC in a murine tumor observed by two-color confocal fluorescence imaging and spectroscopy in a whole-mount model. Photochem Photobiol. 2005 Sep-Oct; 81(5):1123-30.
    View in: PubMed
  25. Mitra S, Foster TH. Photophysical parameters, photosensitizer retention and tissue optical properties completely account for the higher photodynamic efficacy of meso-tetra-hydroxyphenyl-chlorin vs Photofrin. Photochem Photobiol. 2005 Jul-Aug; 81(4):849-59.
    View in: PubMed
  26. Finlay JC, Mitra S, Patterson MS, Foster TH. Photobleaching kinetics of Photofrin in vivo and in multicell tumour spheroids indicate two simultaneous bleaching mechanisms. Phys Med Biol. 2004 Nov 7; 49(21):4837-60.
    View in: PubMed
  27. Mitra S, Foster TH. Carbogen breathing significantly enhances the penetration of red light in murine tumours in vivo. Phys Med Biol. 2004 May 21; 49(10):1891-904.
    View in: PubMed
  28. Mitra S, Goren EM, Frelinger JG, Foster TH. Activation of heat shock protein 70 promoter with meso-tetrahydroxyphenyl chlorin photodynamic therapy reported by green fluorescent protein in vitro and in vivo. Photochem Photobiol. 2003 Dec; 78(6):615-22.
    View in: PubMed
  29. Finlay JC, Mitra S, Foster TH. In vivo mTHPC photobleaching in normal rat skin exhibits unique irradiance-dependent features. Photochem Photobiol. 2002 Mar; 75(3):282-8.
    View in: PubMed
  30. Bigelow CE, Mitra S, Knuechel R, Foster TH. ALA- and ALA-hexylester-induced protoporphyrin IX fluorescence and distribution in multicell tumour spheroids. Br J Cancer. 2001 Sep 1; 85(5):727-34.
    View in: PubMed
  31. Mitra S, Finlay JC, McNeill D, Conover DL, Foster TH. Photochemical oxygen consumption, oxygen evolution and spectral changes during UVA irradiation of EMT6 spheroids. Photochem Photobiol. 2001 Jun; 73(6):703-8.
    View in: PubMed
  32. Coutier S, Mitra S, Bezdetnaya LN, Parache RM, Georgakoudi I, Foster TH, Guillemin F. Effects of fluence rate on cell survival and photobleaching in meta-tetra-(hydroxyphenyl)chlorin-photosensitized Colo 26 multicell tumor spheroids. Photochem Photobiol. 2001 Mar; 73(3):297-303.
    View in: PubMed
  33. Mitra S, Foster TH. Photochemical oxygen consumption sensitized by a porphyrin phosphorescent probe in two model systems. Biophys J. 2000 May; 78(5):2597-605.
    View in: PubMed

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