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Jiong Wang

TitleResearch Assistant Professor
InstitutionSchool of Medicine and Dentistry
DepartmentMedicine
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 675
Rochester NY 14642
 
 Awards And Honors
1997     Science and Technology Advancement Award of Yunnan Province, China  | Government
1998     Science and Technology Advancement Award of Yunnan Province, China  | Government
2001     Science and Technology Advancement Award of Yunnan Province, China  | Government
2004     Science and Technology Advancement Award of Yunnan Province, China  | Government
 
 Selected Publications
List All   |   Timeline
  1. Wang J, Li D, Bambara RA, Dykes C. Reverse transcriptase backbone can alter the polymerization and RNase activities of non-nucleoside reverse transcriptase mutants K101E+G190S. J Gen Virol. 2013 Oct; 94(Pt 10):2297-308.
    View in: PubMed
  2. Wang J, Li D, Bambara RA, Yang H, Dykes C. L74V increases the reverse transcriptase content of HIV-1 virions with non-nucleoside reverse transcriptase drug-resistant mutations L100I+K103N and K101E+G190S, which results in increased fitness. J Gen Virol. 2013 Jul; 94(Pt 7):1597-607.
    View in: PubMed
  3. Wang J, Zhang G, Bambara RA, Li D, Liang H, Wu H, Smith HM, Lowe NR, Demeter LM, Dykes C. Nonnucleoside reverse transcriptase inhibitor-resistant HIV is stimulated by efavirenz during early stages of infection. J Virol. 2011 Oct; 85(20):10861-73.
    View in: PubMed
  4. Wang J, Bambara RA, Demeter LM, Dykes C. Reduced fitness in cell culture of HIV-1 with nonnucleoside reverse transcriptase inhibitor-resistant mutations correlates with relative levels of reverse transcriptase content and RNase H activity in virions. J Virol. 2010 Sep; 84(18):9377-89.
    View in: PubMed
  5. Wang J, Jin X. HIV vaccine could use a little help. Hum Vaccin. 2010 Jun; 6(6):476-81.
    View in: PubMed
  6. Wang J, Liang H, Bacheler L, Wu H, Deriziotis K, Demeter LM, Dykes C. The non-nucleoside reverse transcriptase inhibitor efavirenz stimulates replication of human immunodeficiency virus type 1 harboring certain non-nucleoside resistance mutations. Virology. 2010 Jul 5; 402(2):228-37.
    View in: PubMed
  7. Koval CE, Dykes C, Wang J, Demeter LM. Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V. Virology. 2006 Sep 15; 353(1):184-92.
    View in: PubMed
  8. Dykes C, Wang J, Jin X, Planelles V, An DS, Tallo A, Huang Y, Wu H, Demeter LM. Evaluation of a multiple-cycle, recombinant virus, growth competition assay that uses flow cytometry to measure replication efficiency of human immunodeficiency virus type 1 in cell culture. J Clin Microbiol. 2006 Jun; 44(6):1930-43.
    View in: PubMed
  9. Wang J, Dykes C, Domaoal RA, Koval CE, Bambara RA, Demeter LM. The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in replication efficiency. Virology. 2006 May 10; 348(2):462-74.
    View in: PubMed

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