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Randeep Kashyap

TitleAssociate Professor
InstitutionSchool of Medicine and Dentistry
DepartmentSurgery
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box SURG
Rochester NY 14642
 
 Awards And Honors
1981     Prize for standing first in premedical examination with distinction.
1996     Awarded certificate in an advanced transplantation teaching program from University Hospital Birmingham , England
1999     Awarded the Oxford Travel Scholarship Award to attend BAUS Transplantatio Course. Cambridge, England
2009     Awarded Fellowship to the American College of Surgeons
2009     Cambridge WHO's WHO
 
 Overview
Dr. Randeep Kashyap earned his bachelor in medicine and bachelor of surgery (MBBS) in 1986 from Punjab University, Chandigarh, India by graduating with honors. He also pursued his master in surgery from the same university. After completing the residency program in surgery, he joined the University of Pittsburgh Medical Center's transplantation surgery fellowship program and was later appointed a visiting instructor.

Dr. Kashyap began at the University of Rochester Medical Center in 2003 as a post-doctoral research fellow and subsequently, as a clinical fellow in the Solid Organ Transplant and Hepatobiliary Surgery Division. Additionally, Dr. Kashyap has contributed to over 50 publications in peer-reviewed international and national journals, as either first or second/third author. A number of his publications have become landmark papers in the field of transplantation and basic research – supported by grants from the National Institute of Health. He is married and has two sons.

 
 Selected Publications
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  1. Sasson T, Wing RE, Foster TH, Kashyap R, Butani D, Waldman DL. Assisted maturation of native fistula in two patients with a continuous flow left ventricular assist device. J Vasc Interv Radiol. 2014 May; 25(5):781-3.
    View in: PubMed
  2. Connolly GC, Safadjou S, Kashyap R, Chen R, Orloff MS, Hezel AF. Diabetes mellitus impacts risk of macrovascular invasion in patients undergoing transplantation for hepatocellular carcinoma. BMC Gastroenterol. 2013; 13:9.
    View in: PubMed
  3. Katz AW, Chawla S, Qu Z, Kashyap R, Milano MT, Hezel AF. Stereotactic hypofractionated radiation therapy as a bridge to transplantation for hepatocellular carcinoma: clinical outcome and pathologic correlation. Int J Radiat Oncol Biol Phys. 2012 Jul 1; 83(3):895-900.
    View in: PubMed
  4. Jain A, Singhal A, Kashyap R, Safadjou S, Ryan CK, Orloff MS. Comparative analysis of hepatitis C recurrence and fibrosis progression between deceased-donor and living-donor liver transplantation: 8-year longitudinal follow-up. Transplantation. 2011 Aug 27; 92(4):453-60.
    View in: PubMed
  5. Zand MS, Orloff MS, Abt P, Patel S, Tsoulfas G, Kashyap R, Jain A, Safadjou S, Bozorgzadeh A. High mortality in orthotopic liver transplant recipients who require hemodialysis. Clin Transplant. 2011 Mar-Apr; 25(2):213-21.
    View in: PubMed
  6. Agarwal S, Gandhi M, Kashyap R, Liebman S. Spontaneous rupture of a silicone peritoneal dialysis catheter presenting outflow failure and peritonitis. Perit Dial Int. 2011 Mar-Apr; 31(2):204-6.
    View in: PubMed
  7. Udgiri N, Oberoi A, Kashyap R, Raghavan K, Kella V. A new law for allocation of donor organs in Israel. Lancet. 2010 Jul 24; 376(9737):231; author reply 231-2.
    View in: PubMed
  8. Kashyap R, Safadjou S, Chen R, Mantry P, Sharma R, Patil V, Maloo M, Ryan C, Marroquin C, Barry C, Ramaraju G, Maliakkal B, Orloff M. Living donor and deceased donor liver transplantation for autoimmune and cholestatic liver diseases--an analysis of the UNOS database. J Gastrointest Surg. 2010 Sep; 14(9):1362-9.
    View in: PubMed
  9. Jain AB, Patil V, Sheikh B, Apostolakos M, Ryan C, Kashyap R, Orloff M. Effect of liver transplant on pulmonary functions in adult patients with alpha 1 antitrypsin deficiency: 7 cases. Exp Clin Transplant. 2010 Mar; 8(1):4-8.
    View in: PubMed
  10. Sharma R, Kashyap R, Jain A, Safadjou S, Graham M, Dwivedi AK, Orloff M. Surgical complications following liver transplantation in patients with portal vein thrombosis--a single-center perspective. J Gastrointest Surg. 2010 Mar; 14(3):520-7.
    View in: PubMed
  11. Jain A, Nemitz P, Sharma R, Sheikh B, Safadjou S, Vetter M, Brayan L, Batzold P, Kashyap R, Orloff M. Incidence of abdominal wall numbness post-liver transplantation and its complications. Liver Transpl. 2009 Nov; 15(11):1488-92.
    View in: PubMed
  12. Kashyap R, Ryan C, Sharma R, Maloo MK, Safadjou S, Graham M, Tretheway D, Jain A, Orloff M. Liver grafts from donors with central nervous system tumors: a single-center perspective. Liver Transpl. 2009 Oct; 15(10):1204-8.
    View in: PubMed
  13. Jain A, Fiaz O, Sheikh B, Sharma R, Safadjou S, Kashyap R, Bryan L, Batzold P, Orloff M. Recurrent nonhepatic and de novo malignancies after liver transplantation. Transplantation. 2009 Sep 15; 88(5):706-10.
    View in: PubMed
  14. Kashyap R, Mantry P, Sharma R, Maloo MK, Safadjou S, Qi Y, Jain A, Maliakkal B, Ryan C, Orloff M. Comparative analysis of outcomes in living and deceased donor liver transplants for primary sclerosing cholangitis. J Gastrointest Surg. 2009 Aug; 13(8):1480-6.
    View in: PubMed
  15. Jain A, Sharma R, Ryan C, Safadjou S, Kashyap R, Mantry P, Maliakkal B, Orloff M. Response to antiviral therapy in liver transplant recipients with recurrent hepatitis C viral infection: a single center experience. Clin Transplant. 2010 Jan-Feb; 24(1):104-11.
    View in: PubMed
  16. Jain A, Patil VP, Horton P, Patel N, Kashyap R, Tsoulfas G, Orloff M, Bozorgzadeh A. Common iliac artery lying posterior to psoas major identified during kidney transplantation. Transplantation. 2008 Aug 27; 86(4):623-4.
    View in: PubMed
  17. Kashyap R, Bozorgzadeh A, Abt P, Tsoulfas G, Maloo M, Sharma R, Patel S, Dombroski D, Mantry P, Safadjou S, Jain A, Orloff M. Stratifying risk of biliary complications in adult living donor liver transplantation by magnetic resonance cholangiography. Transplantation. 2008 Jun 15; 85(11):1569-72.
    View in: PubMed
  18. Jain A, Venkataramanan R, Sharma R, Kwong T, Abt P, Orloff M, Kashyap R, Tsoulfas G, Bozorgzadeh A. Pharmacokinetics of mycophenolic acid in live donor liver transplant patients vs deceased donor liver transplant patients. J Clin Pharmacol. 2008 May; 48(5):547-52.
    View in: PubMed
  19. Jain A, Venkataramanan R, Sharma R, Kwong T, Orloff M, Abt P, Kashyap R, Tsoulfas G, Batzold P, Williamson M, Bozorgzadeh A. Pharmacokinetics of tacrolimus in living donor liver transplant and deceased donor liver transplant recipients. Transplantation. 2008 Feb 27; 85(4):554-60.
    View in: PubMed
  20. Patel S, Cassuto J, Orloff M, Tsoulfas G, Zand M, Kashyap R, Jain A, Bozorgzadeh A, Abt P. Minimizing morbidity of organ donation: analysis of factors for perioperative complications after living-donor nephrectomy in the United States. Transplantation. 2008 Feb 27; 85(4):561-5.
    View in: PubMed
  21. Jain A, Sharma R, Ryan C, Tsoulfas G, Orloff M, Abt P, Kashyap R, Batzold P, Sauberman L, Safadjou S, Graham M, Bozorgzadeh A. Potential immunological advantage of intravenous mycophenolate mofetil with tacrolimus and steroids in primary deceased donor liver transplantation and live donor liver transplantation without antibody induction. Liver Transpl. 2008 Feb; 14(2):202-9.
    View in: PubMed
  22. Nickels M, Jain A, Sharma R, Orloff M, Tsoulfas G, Kashyap R, Bozorgzadeh A. Polysubstance abuse in liver transplant patients and its impact on survival outcome. Exp Clin Transplant. 2007 Dec; 5(2):680-5.
    View in: PubMed
  23. Patel S, Orloff M, Tsoulfas G, Kashyap R, Jain A, Bozorgzadeh A, Abt P. Living-donor liver transplantation in the United States: identifying donors at risk for perioperative complications. Am J Transplant. 2007 Oct; 7(10):2344-9.
    View in: PubMed
  24. Bozorgzadeh A, Orloff M, Abt P, Tsoulfas G, Younan D, Kashyap R, Jain A, Mantry P, Maliakkal B, Khorana A, Schwartz S. Survival outcomes in liver transplantation for hepatocellular carcinoma, comparing impact of hepatitis C versus other etiology of cirrhosis. Liver Transpl. 2007 Jun; 13(6):807-13.
    View in: PubMed
  25. Jain A, Venkataramanan R, Kwong T, Mohanka R, Orloff M, Abt P, Kashyap R, Tsoulfas G, Mack C, Williamson M, Batzold P, Bozorgzadeh A. Pharmacokinetics of mycophenolic acid in liver transplant patients after intravenous and oral administration of mycophenolate mofetil. Liver Transpl. 2007 Jun; 13(6):791-6.
    View in: PubMed
  26. Abt P, Kashyap R, Orloff M, Jain A, Tsoulfas G, Bozorgzadeh A, Olthoff K. Pediatric liver and kidney transplantation with allografts from DCD donors: A review of UNOS data. Transplantation. 2006 Dec 27; 82(12):1708-11.
    View in: PubMed
  27. Jain A, Orloff M, Abt P, Kashyap R, Mantry P, Bozorgzadeh A. Postoperative impact of intraoperative biochemical changes at the completion of parenchymal division in living-donor liver transplantation. Exp Clin Transplant. 2006 Dec; 4(2):544-8.
    View in: PubMed
  28. Maloo M, Abt P, Kashyap R, Younan D, Zand M, Orloff M, Jain A, Pentland A, Scott G, Bozorgzadeh A. Nephrogenic systemic fibrosis among liver transplant recipients: a single institution experience and topic update. Am J Transplant. 2006 Sep; 6(9):2212-7.
    View in: PubMed
  29. Udgiri N, Kashyap R, Minz M. Nephron dosing and low-grade proteinuria. Am J Transplant. 2006 Jun; 6(6):1494; author reply 1495.
    View in: PubMed
  30. Jain A, Mohanka R, Orloff M, Abt P, Kashyap R, Cullen J, Lansing K, Bozorgzadeh A. University of Wisconsin versus histidine-tryptophan-ketoglutarate for tissue preservation in live-donor liver transplantation. Exp Clin Transplant. 2006 Jun; 4(1):451-7.
    View in: PubMed
  31. Angona R, Abt P, Younan D, Massey T, Marvin M, Kashyap R, Richards D, Jones K, Queschenbach J, Zand M, Jain A, Orloff M, Bozorgzadeh A. Modification of a biventricular assist device to facilitate preservative infusion and organ recovery in a nonheart-beating donor. J Extra Corpor Technol. 2006 Jun; 38(2):157-60.
    View in: PubMed
  32. Jain A, Mohanka R, Orloff M, Abt P, Kashyap R, Kelley M, Burlee K, Bozorgzadeh A. Intravenous mycophenolate mofetil with low-dose oral tacrolimus and steroid induction for live donor liver transplantation. Exp Clin Transplant. 2005 Dec; 3(2):361-5.
    View in: PubMed
  33. Jain A, Orloff M, Abt P, Kashyap R, Mohanka R, Lansing K, Bozorgzadeh A. Transplantation of liver grafts from older donors: impact on recipients with hepatitis C virus infection. Transplant Proc. 2005 Sep; 37(7):3162-4.
    View in: PubMed
  34. Kelley M, Jain A, Kashyap R, Orloff M, Abt P, Wrobble K, Venkataramanan R, Bozorgzadeh A. Change in oral absorption of tacrolimus in a liver transplant recipient after reversal of jejunoileal bypass: case report. Transplant Proc. 2005 Sep; 37(7):3165-7.
    View in: PubMed
  35. Jain A, Orloff M, Kashyap R, Lansing K, Betts R, Mohanka R, Menegus M, Ryan C, Bozorgzadeh A. Does valganciclovir hydrochloride (valcyte) provide effective prophylaxis against cytomegalovirus infection in liver transplant recipients? Transplant Proc. 2005 Sep; 37(7):3182-6.
    View in: PubMed
  36. Jain A, Orloff M, Abt P, Kashyap R, Mohanka R, Lansing K, Kelley M, Bozorgzadeh A. Use of hepatitis B core antibody-positive liver allograft in hepatitis C virus-positive and -negative recipients with use of short course of hepatitis B immunoglobulin and Lamivudine. Transplant Proc. 2005 Sep; 37(7):3187-9.
    View in: PubMed
  37. Jain A, Vekatramanan R, Yelochan B, Kashyap R, Marcos A, Fung J. Ribavirin levels in post liver transplant patients treated for recurrent hepatitis C viral infection. Transplant Proc. 2005 Sep; 37(7):3190-6.
    View in: PubMed
  38. Jain A, Orloff M, Abt P, Kashyap R, Mohanka R, Lansing K, Romano J, Bozorgzadeh A. Survival outcome after hepatic retransplantation for hepatitis C virus-positive and -negative recipients. Transplant Proc. 2005 Sep; 37(7):3159-61.
    View in: PubMed
  39. Jain A, Marcos A, Reyes J, Mazariagos G, Kashyap R, Eghtesad B, Marsh W, Fontas P, De Vera M, Costa G, Patel K, Gadomski M, Starzl T, Fung J. Tacrolimus for primary liver transplantation: 12 to 15 years actual follow-up with safety profile. Transplant Proc. 2005 Mar; 37(2):1207-10.
    View in: PubMed
  40. Minz M, Sharma A, Mahawar K, Heer M, Kashyap R. Successful live related renal transplant in a case of tuberous sclerosis. J Assoc Physicians India. 2005 Jan; 53:43-5.
    View in: PubMed
  41. Thomas R, Minz M, Singh B, Heer M, Kashyap R. Role of postdose cyclosporine monitoring in living renal transplant recipients. Transplant Proc. 2004 Sep; 36(7):2104.
    View in: PubMed
  42. Minz RW, Minz M, Kashyap R, Heer M, Udgiri N, Joshi K, Sakhuja VK. Therapeutic implication of quantitative pp65 antigen assay in living renal transplant in a high seroendemic population. Transplant Proc. 2004 Sep; 36(7):2120-1.
    View in: PubMed
  43. Udgiri N, Minz M, Kashyap R, Heer M, Gupta CS, Mohandas K, Minz RW, Malla N. Intestinal cryptosporidiasis in living related renal transplant recipients. Transplant Proc. 2004 Sep; 36(7):2128-9.
    View in: PubMed
  44. Minz M, Udgiri NK, Heer MK, Kashyap R, Malla N. Cryptosporidiasis in live related renal transplant recipients: a single center experience. Transplantation. 2004 Jun 27; 77(12):1916-7.
    View in: PubMed
  45. Udgiri NR, Kashyap R, Minz M. Effect of obesity on renal transplant outcomes. Transplantation. 2003 Dec 15; 76(11):1652; author reply 1651.
    View in: PubMed
  46. Minz M, Kashyap R, Udgiri NR. Is there a solution to organ commerce in non-directed donors? Lancet. 2003 Oct 18; 362(9392):1335.
    View in: PubMed
  47. Udgiri NR, Kashyap R, Minz M. SA: Re Ross et al. Transplantation. 2003 May 27; 75(10):1763-4; author reply 1762-3.
    View in: PubMed
  48. Minz M, Sharma A, Kashyap R, Udgiri N, Heer M, Kumar V, Vaiphei K. Isolated renal allograft arterial mucormycosis: an extremely rare complication. Nephrol Dial Transplant. 2003 May; 18(5):1034-5.
    View in: PubMed
  49. Udgiri N, Kashyap R, Minz M. Risk factors for late kidney allograft failure. Kidney Int. 2003 May; 63(5):1960-1; author reply 1961.
    View in: PubMed
  50. Jain A, Mazariegos G, Pokharna R, Parizhskaya M, Kashyap R, Kosmach-Park B, Smith A, Fung JJ, Reyes J. The absence of chronic rejection in pediatric primary liver transplant patients who are maintained on tacrolimus-based immunosuppression: a long-term analysis. Transplantation. 2003 Apr 15; 75(7):1020-5.
    View in: PubMed
  51. Udgiri NR, Kashyap R, Minz M. The impact of body mass index on renal transplant outcomes: a significant independent risk factor for graft failure and patient death. Transplantation. 2003 Jan 27; 75(2):249.
    View in: PubMed
  52. Jain AB, Eghtesad B, Venkataramanan R, Fontes PA, Kashyap R, Dvorchik I, Shakil AO, Kingery L, Fung JJ. Ribavirin dose modification based on renal function is necessary to reduce hemolysis in liver transplant patients with hepatitis C virus infection. Liver Transpl. 2002 Nov; 8(11):1007-13.
    View in: PubMed
  53. Jain A, Mazariegos G, Pokharna R, Parizhskaya M, Smith A, Kashyap R, Fung JJ, Reyes J. Almost total absence of chronic rejection in primary pediatric liver transplantation under tacrolimus. Transplant Proc. 2002 Aug; 34(5):1968-9.
    View in: PubMed
  54. Jain A, Pokharna R, Eghtesad B, Potdar S, Kashyap R, Kingery L, Fung J. Steroid withdrawal under tacrolimus for primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis after liver transplantation and long-term survival. Transplant Proc. 2002 Aug; 34(5):1524-5.
    View in: PubMed
  55. Jain A, Mazariegos G, Kashyap R, Kosmach-Park B, Starzl TE, Fung JJ, Reyes J. Pediatric liver transplantation in 808 consecutive children: 20-years experience from a single center. Transplant Proc. 2002 Aug; 34(5):1955-7.
    View in: PubMed
  56. Jain A, Mazariegos G, Kashyap R, Kosmach-Park B, Starzl TE, Fung J, Reyes J. Pediatric liver transplantation. A single center experience spanning 20 years. Transplantation. 2002 Mar 27; 73(6):941-7.
    View in: PubMed
  57. Jain A, Kashyap R, Demetris AJ, Eghstesad B, Pokharna R, Fung JJ. A prospective randomized trial of mycophenolate mofetil in liver transplant recipients with hepatitis C. Liver Transpl. 2002 Jan; 8(1):40-6.
    View in: PubMed
  58. Jain A, Kashyap R, Dodson F, Kramer D, Hamad I, Khan A, Eghestad B, Starzl TE, Fung JJ. A prospective randomized trial of tacrolimus and prednisone versus tacrolimus, prednisone and mycophenolate mofetil in primary adult liver transplantation: a single center report. Transplantation. 2001 Sep 27; 72(6):1091-7.
    View in: PubMed
  59. Jain A, Demetris AJ, Kashyap R, Blakomer K, Ruppert K, Khan A, Rohal S, Starzl TE, Fung JJ. Does tacrolimus offer virtual freedom from chronic rejection after primary liver transplantation? Risk and prognostic factors in 1,048 liver transplantations with a mean follow-up of 6 years. Liver Transpl. 2001 Jul; 7(7):623-30.
    View in: PubMed
  60. Jain A, Kashyap R, Marsh W, Rohal S, Khanna A, Fung JJ. Reasons for long-term use of steroid in primary adult liver transplantation under tacrolimus. Transplantation. 2001 Apr 27; 71(8):1102-6.
    View in: PubMed
  61. Jain A, Mazariegos G, Kashyap R, Marsh W, Khanna A, Iurlano K, Fung J, Reyes J. Reasons why some children receiving tacrolimus therapy require steroids more than 5 years post liver transplantation. Pediatr Transplant. 2001 Apr; 5(2):93-8.
    View in: PubMed
  62. Randhawa P, Blakolmer K, Kashyap R, Raikow R, Nalesnik M, Demetris AJ, Jain A. Allograft liver biopsy in patients with Epstein-Barr virus-associated posttransplant lymphoproliferative disease. Am J Surg Pathol. 2001 Mar; 25(3):324-30.
    View in: PubMed
  63. Jain A, Kashyap R, Kramer D, Dodson F, Hamad I, Starzl TE, Fung JJ. Prospective randomized trial of tacrolimus and prednisone versus tacrolimus, prednisone, and mycophenolate mofetil: complete report on 350 primary adult liver transplantations. Transplant Proc. 2001 Feb-Mar; 33(1-2):1342-4.
    View in: PubMed
  64. Kashyap R, Jain A, Reyes J, Demetris AJ, Elmagd KA, Dodson SF, Marsh W, Madariaga V, Mazariegos G, Geller D, Bonham CA, Cacciarelli T, Fontes P, Starzl TE, Fung JJ. Causes of death after liver transplantation in 4000 consecutive patients: 2 to 19 year follow-up. Transplant Proc. 2001 Feb-Mar; 33(1-2):1482-3.
    View in: PubMed
  65. Kashyap R, Jain A, Reyes J, Demetris AJ, Elmagd KA, Dodson SF, Marsh W, Madariaga V, Mazariegos G, Geller D, Bonham CA, Cacciarelli T, Fontes P, Starzl TE, Fung JJ. Causes of retransplantation after primary liver transplantation in 4000 consecutive patients: 2 to 19 years follow-up. Transplant Proc. 2001 Feb-Mar; 33(1-2):1486-7.
    View in: PubMed
  66. Jain A, DiMartini A, Kashyap R, Youk A, Rohal S, Fung J. Long-term follow-up after liver transplantation for alcoholic liver disease under tacrolimus. Transplantation. 2000 Nov 15; 70(9):1335-42.
    View in: PubMed
  67. Jain A, Reyes J, Kashyap R, Dodson SF, Demetris AJ, Ruppert K, Abu-Elmagd K, Marsh W, Madariaga J, Mazariegos G, Geller D, Bonham CA, Gayowski T, Cacciarelli T, Fontes P, Starzl TE, Fung JJ. Long-term survival after liver transplantation in 4,000 consecutive patients at a single center. Ann Surg. 2000 Oct; 232(4):490-500.
    View in: PubMed
  68. Chang CC, Sakashita N, Ornvold K, Lee O, Chang ET, Dong R, Lin S, Lee CY, Strom SC, Kashyap R, Fung JJ, Farese RV, Patoiseau JF, Delhon A, Chang TY. Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine. J Biol Chem. 2000 Sep 8; 275(36):28083-92.
    View in: PubMed
  69. Jain A, Mazariegos G, Kashyap R, Green M, Gronsky C, Starzl TE, Fung J, Reyes J. Comparative long-term evaluation of tacrolimus and cyclosporine in pediatric liver transplantation. Transplantation. 2000 Aug 27; 70(4):617-25.
    View in: PubMed
  70. Reyes J, Jain A, Mazariegos G, Kashyap R, Green M, Iurlano K, Fung J. Long-term results after conversion from cyclosporine to tacrolimus in pediatric liver transplantation for acute and chronic rejection. Transplantation. 2000 Jun 27; 69(12):2573-80.
    View in: PubMed
  71. Jain A, Reyes J, Kashyap R, Rohal S, Abu-Elmagd K, Starzl T, Fung J. What have we learned about primary liver transplantation under tacrolimus immunosuppression? Long-term follow-up of the first 1000 patients. Ann Surg. 1999 Sep; 230(3):441-8; discussion 448-9.
    View in: PubMed
  72. Jain AB, Kashyap R, Rakela J, Starzl TE, Fung JJ. Primary adult liver transplantation under tacrolimus: more than 90 months actual follow-up survival and adverse events. Liver Transpl Surg. 1999 Mar; 5(2):144-50.
    View in: PubMed
  73. Kashyap R, Shapiro R, Jordan M, Randhawa PS. The clinical significance of cytomegaloviral inclusions in the allograft kidney. Transplantation. 1999 Jan 15; 67(1):98-103.
    View in: PubMed

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