Yoshihiko Murata
| Title | Associate Professor |
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| Institution | School of Medicine and Dentistry |
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| Department | Medicine |
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| Address | University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 689
Rochester NY 14642
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| Buswell Research Fellowship, Department of Medicine, 2007-8 | Univ of Rochester School of Medicine and Dentistry | |
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| Richard O. Burns Award for Outstanding Research | Dept of Microbiology, Duke University, 1995 | |
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| Medical Scientist Training Program Predoctoral Fellowship | Duke University School of Medicine, 1989-1997 | |
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| Honors Program in Biological Sciences, Stanford University, 1988-89 | |
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| Juvenile Diabetes Foundation Summer Fellow, Stanford University, 1988 | |
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| Undergraduate Research Grants, Stanford University, 1987-1989 |
My current research interests include: 1) host immune response and preclinical vaccine development against respiratory syncytial virus (RSV) and related respiratory viruses; 2) clinical studies of respiratory viruses and bacterial infections in adults; and 3) development of novel antimicrobial agents against Acinetobacter baumanni and other Gram-negative ESKAPE pathogens.
Relevant publications:
1. Murata Y, Catherman SC. Antibody response to the central unglycosylated region of the respiratory syncytial virus attachment protein in mice. Vaccine 30: 5382-8, 2012.
2. Murata Y, Lightfoote PM, Biear JN, Falsey AR, Walsh EE. Humoral response to the central unglycosylated region of the respiratory syncytial virus attachment protein. Vaccine 28: 6242-6, 2010.
3. Murata Y, Lightfoote PM, Falsey AR, Walsh EE. Identification of and human serum reactogenicity to neutralizing epitopes within the central unglycosylated region of the respiratory syncytial virus attachment protein. Clin Vaccine Immunol 17: 695-697, 2010.
4. Murata Y, Lightfoote PM, Rose RC, Walsh EE. Antigenic presentation of heterologous epitopes engineered into the outer surface-exposed helix 4 loop region of human papillomavirus L1 capsomeres. Virol J 2009; 6: 81.
5. .Murata Y, Walsh EE, Falsey, AR. Pulmonary complications of inter-pandemic influenza A in hospitalized adults. J Infect Dis 195: 1029-1037, 2007.
6 .Falsey AR, Murata Y, Walsh EE. Impact of rapid diagnosis on management of adults hospitalized with influenza. Arch Intern Med 167: 354-360, 2007.
Review Articles (Peer Reviewed):
1.Murata Y and Falsey AR. Respiratory syncytial virus infection in adults. Antiviral Therapy 12: 659-670, 2007.
2.Murata Y. Respiratory syncytial virus infection in adults. Curr Opin Pulm Med 14: 235-240, 2008.
Book chapters:
1.Murata Y and Falsey AR. RSV Infection in Elderly Adults. In: Cane P ed., Respiratory Syncytial Virus, Perspectives in Medical Virology Vol. 14 (Elsevier, Oxford, UK, 2007), pp. 163-181.
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Murata Y, Catherman SC. Antibody response to the central unglycosylated region of the respiratory syncytial virus attachment protein in mice. Vaccine. 2012 Aug 3; 30(36):5382-8.
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Murata Y, Lightfoote PM, Biear JN, Falsey AR, Walsh EE. Humoral response to the central unglycosylated region of the respiratory syncytial virus attachment protein. Vaccine. 2010 Aug 31; 28(38):6242-6.
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Murata Y, Lightfoote PM, Falsey AR, Walsh EE. Identification of and human serum reactogenicity to neutralizing epitopes within the central unglycosylated region of the respiratory syncytial virus attachment protein. Clin Vaccine Immunol. 2010 Apr; 17(4):695-7.
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Murata Y. Respiratory syncytial virus vaccine development. Clin Lab Med. 2009 Dec; 29(4):725-39.
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Murata Y, Lightfoote PM, Rose RC, Walsh EE. Antigenic presentation of heterologous epitopes engineered into the outer surface-exposed helix 4 loop region of human papillomavirus L1 capsomeres. Virol J. 2009; 6:81.
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Murata Y. Respiratory syncytial virus infection in adults. Curr Opin Pulm Med. 2008 May; 14(3):235-40.
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Murata Y, Walsh EE, Falsey AR. Pulmonary complications of interpandemic influenza A in hospitalized adults. J Infect Dis. 2007 Apr 1; 195(7):1029-37.
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Falsey AR, Murata Y, Walsh EE. Impact of rapid diagnosis on management of adults hospitalized with influenza. Arch Intern Med. 2007 Feb 26; 167(4):354-60.
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Murata Y, Falsey AR. Respiratory syncytial virus infection in adults. Antivir Ther. 2007; 12(4 Pt B):659-70.
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Wharton RP, Sonoda J, Lee T, Patterson M, Murata Y. The Pumilio RNA-binding domain is also a translational regulator. Mol Cell. 1998 May; 1(6):863-72.
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Sterner JM, Murata Y, Kim HG, Kennett SB, Templeton DJ, Horowitz JM. Detection of a novel cell cycle-regulated kinase activity that associates with the amino terminus of the retinoblastoma protein in G2/M phases. J Biol Chem. 1995 Apr 21; 270(16):9281-8.
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Murata Y, Kim HG, Rogers KT, Udvadia AJ, Horowitz JM. Negative regulation of Sp1 trans-activation is correlated with the binding of cellular proteins to the amino terminus of the Sp1 trans-activation domain. J Biol Chem. 1994 Aug 12; 269(32):20674-81.
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Udvadia AJ, Rogers KT, Higgins PD, Murata Y, Martin KH, Humphrey PA, Horowitz JM. Sp-1 binds promoter elements regulated by the RB protein and Sp-1-mediated transcription is stimulated by RB coexpression. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3265-9.
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Arita T, Murata Y, Lin LR, Tsuji T, Reddy VN. Synthesis of lens capsule in long-term culture of human lens epithelial cells. Invest Ophthalmol Vis Sci. 1993 Feb; 34(2):355-62.
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Tavangar K, Murata Y, Pedersen ME, Goers JF, Hoffman AR, Kraemer FB. Regulation of lipoprotein lipase in the diabetic rat. J Clin Invest. 1992 Nov; 90(5):1672-8.
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Tsuji T, Lin LR, Murata Y, Reddy VN. Immunohistochemical localization of Na,K-ATPase in the in situ lens, cultured human lens epithelium and lentoid. Exp Eye Res. 1992 Sep; 55(3):469-78.
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Tavangar K, Murata Y, Patel S, Kalinyak JE, Pedersen ME, Goers JF, Hoffman AR, Kraemer FB. Developmental regulation of lipoprotein lipase in rats. Am J Physiol. 1992 Mar; 262(3 Pt 1):E330-7.
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Murata Y, Behr SR, Kraemer FB. Regulation of macrophage lipoprotein lipase secretion by the scavenger receptor. Biochim Biophys Acta. 1988 Oct 28; 972(1):17-24.
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