Abdellatif Benraiss
| Title | Assistant Professor |
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| Institution | School of Medicine and Dentistry |
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| Department | Neurology in the Center for Translational Neuromedicine |
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| Address | University of Rochester Medical Center School of Medicine and Dentistry 601 Elmwood Ave, Box 645 Rochester NY 14642
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| Title | Assistant Professor |
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| Institution | School of Medicine and Dentistry |
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| Department | Neurosurgery |
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| 2001 |
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| Cornell Medical School Aging Foundation Award. | | 2003 |
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| Gene therapy for metachromatic leukodystrophy by intracerebral adeno-associated virus-mediated gene transfer
Dr Nathalie Cartier and M. Abdelatiff Benraiss – INSERM U 561/Paris-€ 62,000 | | 2004 |
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| Gene therapy for metachromatic leukodystrophy by intracerebral adeno-associated virus-mediated gene transfer
Nathalie Cartier and M. Abdelatif Benraiss – INSERM U 561/Paris- € 85,000 |
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Benraiss A, Bruel-Jungerman E, Lu G, Economides AN, Davidson B, Goldman SA. Sustained induction of neuronal addition to the adult rat neostriatum by AAV4-delivered noggin and BDNF. Gene Ther. 2012 May; 19(5):582.
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Benraiss A, Goldman SA. Cellular Therapy and Induced Neuronal Replacement for Huntington's Disease. Neurotherapeutics. 2011 Oct; 8(4):577-90.
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Benraiss A, Bruel-Jungerman E, Lu G, Economides AN, Davidson B, Goldman SA. Sustained induction of neuronal addition to the adult rat neostriatum by AAV4-delivered noggin and BDNF. Gene Ther. 2012 May; 19(5):483-93.
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Hudry E, Van Dam D, Kulik W, De Deyn PP, Stet FS, Ahouansou O, Benraiss A, Delacourte A, Bougnères P, Aubourg P, Cartier N. Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease. Mol Ther. 2010 Jan; 18(1):44-53.
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Cho SR, Benraiss A, Chmielnicki E, Samdani A, Economides A, Goldman SA. Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease. J Clin Invest. 2007 Oct; 117(10):2889-902.
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Sevin C, Verot L, Benraiss A, Van Dam D, Bonnin D, Nagels G, Fouquet F, Gieselmann V, Vanier MT, De Deyn PP, Aubourg P, Cartier N. Partial cure of established disease in an animal model of metachromatic leukodystrophy after intracerebral adeno-associated virus-mediated gene transfer. Gene Ther. 2007 Mar; 14(5):405-14.
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Sevin C, Benraiss A, Van Dam D, Bonnin D, Nagels G, Verot L, Laurendeau I, Vidaud M, Gieselmann V, Vanier M, De Deyn PP, Aubourg P, Cartier N. Intracerebral adeno-associated virus-mediated gene transfer in rapidly progressive forms of metachromatic leukodystrophy. Hum Mol Genet. 2006 Jan 1; 15(1):53-64.
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Auffray C, Gayon R, Benraiss A, Martin N, Laurendeau I, Garaud J, Lucas B, Boitard C, Krief P. An 8-bp deletion in mNOTCH4 intron 10 leads to its retention in mRNA and to synthesis of a truncated protein. Exp Cell Res. 2006 Feb 1; 312(3):233-44.
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Toublanc E, Benraiss A, Bonnin D, Blouin V, Brument N, Cartier N, Epstein AL, Moullier P, Salvetti A. Identification of a replication-defective herpes simplex virus for recombinant adeno-associated virus type 2 (rAAV2) particle assembly using stable producer cell lines. J Gene Med. 2004 May; 6(5):555-64.
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Chmielnicki E, Benraiss A, Economides AN, Goldman SA. Adenovirally expressed noggin and brain-derived neurotrophic factor cooperate to induce new medium spiny neurons from resident progenitor cells in the adult striatal ventricular zone. J Neurosci. 2004 Mar 3; 24(9):2133-42.
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Packer MA, Stasiv Y, Benraiss A, Chmielnicki E, Grinberg A, Westphal H, Goldman SA, Enikolopov G. Nitric oxide negatively regulates mammalian adult neurogenesis. Proc Natl Acad Sci U S A. 2003 Aug 5; 100(16):9566-71.
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Windrem MS, Roy NS, Wang J, Nunes M, Benraiss A, Goodman R, McKhann GM, Goldman SA. Progenitor cells derived from the adult human subcortical white matter disperse and differentiate as oligodendrocytes within demyelinated lesions of the rat brain. J Neurosci Res. 2002 Sep 15; 69(6):966-75.
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Mziaut H, Korza G, Benraiss A, Ozols J. Selective mutagenesis of lysyl residues leads to a stable and active form of delta 9 stearoyl-CoA desaturase. Biochim Biophys Acta. 2002 Jun 13; 1583(1):45-52.
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Benraiss A, Chmielnicki E, Lerner K, Roh D, Goldman SA. Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain. J Neurosci. 2001 Sep 1; 21(17):6718-31.
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Keyoung HM, Roy NS, Benraiss A, Louissaint A, Suzuki A, Hashimoto M, Rashbaum WK, Okano H, Goldman SA. High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain. Nat Biotechnol. 2001 Sep; 19(9):843-50.
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Roy NS, Wang S, Jiang L, Kang J, Benraiss A, Harrison-Restelli C, Fraser RA, Couldwell WT, Kawaguchi A, Okano H, Nedergaard M, Goldman SA. In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus. Nat Med. 2000 Mar; 6(3):271-7.
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Roy NS, Benraiss A, Wang S, Fraser RA, Goodman R, Couldwell WT, Nedergaard M, Kawaguchi A, Okano H, Goldman SA. Promoter-targeted selection and isolation of neural progenitor cells from the adult human ventricular zone. J Neurosci Res. 2000 Feb 1; 59(3):321-31.
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Wang S, Roy NS, Benraiss A, Goldman SA. Promoter-based isolation and fluorescence-activated sorting of mitotic neuronal progenitor cells from the adult mammalian ependymal/subependymal zone. Dev Neurosci. 2000; 22(1-2):167-76.
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Roy NS, Wang S, Harrison-Restelli C, Benraiss A, Fraser RA, Gravel M, Braun PE, Goldman SA. Identification, isolation, and promoter-defined separation of mitotic oligodendrocyte progenitor cells from the adult human subcortical white matter. J Neurosci. 1999 Nov 15; 19(22):9986-95.
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Benraiss A, Arsanto JP, Coulon J, Thouveny Y. Neurogenesis during caudal spinal cord regeneration in adult newts. Dev Genes Evol. 1999 Jun; 209(6):363-9.
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Benraiss A, Arsanto JP, Coulon J, Thouveny Y. Neural crest-like cells originate from the spinal cord during tail regeneration in adult amphibian urodeles. Dev Dyn. 1997 May; 209(1):15-28.
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Benraiss A, Caubit X, Arsanto JP, Coulon J, Nicolas S, Le Parco Y, Thouveny Y. Clonal cell cultures from adult spinal cord of the amphibian urodele Pleurodeles waltl to study the identity and potentialities of cells during tail regeneration. Dev Dyn. 1996 Feb; 205(2):135-49.
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Caubit X, Riou JF, Coulon J, Arsanto JP, Benraiss A, Boucaut JC, Thouveny Y. Tenascin expression in developing, adult and regenerating caudal spinal cord in the urodele amphibians. Int J Dev Biol. 1994 Dec; 38(4):661-72.
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