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M. Iqbal

TitleAssociate Professor
InstitutionSchool of Medicine and Dentistry
DepartmentPathology and Laboratory Medicine
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 608
Rochester NY 14642
 
 Awards And Honors
2010 - 2011Luminex Award  | American College of Medical Genetics Foundation
 
 Overview
Dr. Iqbal's research is in the area of clinical and molecular cytogenetics. He has a particular interest in the application of cytogenetic and FISH testing in the diagnosis of neoplastic as well as genetic disorders. His interests include the molecular cytogenetics of renal cell carcinoma, small round cell tumors, the cytogenetics of leukemia and lymphomas, and prenatal cytogenetic diagnostics. He has special interest in cryptic rearrangements involving subtelomere regions of human chromosomes in genetic disorders and leukemia. Dr. Iqbal is actively involved in bringing microarray technology into use as the next cytogenomics tool to translate lab innovations into postnatal, prenatal and cancer diagnosis.

 
 Selected Publications
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  1. Johnson MD, O'Connell M, Iqbal MA, Williams JP. Radiation effects on human leptomeningeal cell response to cerebrospinal fluid and PDGF-BB. Int J Radiat Biol. 2012 Jul; 88(7):547-55.
    View in: PubMed
  2. Ahmad A, Iqbal MA. Significance of genome-wide analysis of copy number alterations and UPD in myelodysplastic syndromes using combined CGH - SNP arrays. Curr Med Chem. 2012; 19(22):3739-47.
    View in: PubMed
  3. Al-Owain M, Kaya N, Al-Zaidan H, Bin Hussain I, Al-Manea H, Al-Hindi H, Kennedy S, Iqbal MA, Al-Mojalli H, Al-Bakheet A, Puel A, Casanova JL, Al-Muhsen S. Renal failure associated with APECED and terminal 4q deletion: evidence of autoimmune nephropathy. Clin Dev Immunol. 2010; 2010:586342.
    View in: PubMed
  4. Kaya N, Al-Muhsen S, Al-Saud B, Al-Bakheet A, Colak D, Al-Ghonaium A, Al-Dhekri H, Al-Mousa H, Arnaout R, Al-Owain M, Iqbal M. ICF syndrome in Saudi Arabia: immunological, cytogenetic and molecular analysis. J Clin Immunol. 2011 Apr; 31(2):245-52.
    View in: PubMed
  5. Aljurf M, Al Qurashi F, Al Mohareb F, Sahovic E, Al Sharif F, Al Zahrani H, Al Shanqeeti A, Owaidah T, Iqbal A, Zaidi SZ, Nurgat ZA, Sanz M, Chaudhri N. High efficacy and low toxicity of APL induction with concurrent idarubicin/ATRA followed by a novel and simplified outpatient post-remission therapy using single doses of idarubicin and intermittent ATRA. Med Oncol. 2010 Sep; 27(3):702-7.
    View in: PubMed
  6. Chun K, Hagemeijer A, Iqbal A, Slovak ML. Implementation of standardized international karyotype scoring practices is needed to provide uniform and systematic evaluation for patients with myelodysplastic syndrome using IPSS criteria: An International Working Group on MDS Cytogenetics Study. Leuk Res. 2010 Feb; 34(2):160-5.
    View in: PubMed
  7. Iqbal MA, Al-Owain M. Interstitial del(20)(q11.2q12) - clinical and molecular cytogenetic characterization. Am J Med Genet A. 2007 Aug 15; 143A(16):1880-4.
    View in: PubMed
  8. Szych CM, Liesveld JL, Iqbal MA, Li L, Siebert S, Asmus C, O'Malley J, Lee A, Wang N. Isodicentric Philadelphia chromosomes in imatinib mesylate (Gleevec)-resistant patients. Cancer Genet Cytogenet. 2007 Apr 15; 174(2):132-7.
    View in: PubMed
  9. Owaidah TM, Al Beihany A, Iqbal MA, Elkum N, Roberts GT. Cytogenetics, molecular and ultrastructural characteristics of biphenotypic acute leukemia identified by the EGIL scoring system. Leukemia. 2006 Apr; 20(4):620-6.
    View in: PubMed
  10. Hellani A, Al-Hassan S, Iqbal MA, Coskun S. Y chromosome microdeletions in infertile men with idiopathic oligo- or azoospermia. J Exp Clin Assist Reprod. 2006; 3:1.
    View in: PubMed
  11. Iqbal MA, Ramadan S, Ali FA, Kurdi W. Complex de novo cryptic subtelomeric rearrangements in a fetus with multiple ultrasonographic abnormalities and a normal karyotype at amniocentesis. Prenat Diagn. 2005 Dec; 25(12):1142-9.
    View in: PubMed
  12. Al-Mutair A, Iqbal MA, Sakati N, Ashwal A. Cytogenetics and etiology of ambiguous genitalia in 120 pediatric patients. Ann Saudi Med. 2004 Sep-Oct; 24(5):368-72.
    View in: PubMed
  13. Al-Qurashi FH, Owaidah T, Iqbal MA, Aljurf M. Trisomy 4 as the sole karyotypic abnormality in a case of acute biphenotypic leukemia with T-lineage markers in minimally differentiated acute myelocytic leukemia. Cancer Genet Cytogenet. 2004 Apr 1; 150(1):66-9.
    View in: PubMed
  14. Boumah CE, Meyer B, Aljurf M, Bertilsson PA, Pyle RH, Al-Hussein KA, Iqbal A, Gyger M. Monitoring of donor/recipient T-cell engraftment kinetics in myeloablative allogeneic stem cell transplantation using short tandem repeat amplification from cell lysates. Leuk Lymphoma. 2002 Jun; 43(6):1281-7.
    View in: PubMed
  15. Nounou R, Al-Zahrani H H, Ajarim DS, Martin J, Iqbal A, Naufal R, Stuart R, Roberts G, Gyger M. Extramedullary myeloid cell tumours localised to the mediastinum: a rare clinicopathological entity with unique karyotypic features. J Clin Pathol. 2002 Mar; 55(3):221-5.
    View in: PubMed
  16. Iqbal MA, Sakati N, Nester M, Ozand P. Cytogenetic diagnosis of fragile X syndrome: study of 305 suspected cases in Saudi Arabia. Ann Saudi Med. 2000 May-July; 20(3-4):214-7.
    View in: PubMed
  17. Iqbal MA, Akhtar M, Ulmer C, Al-Dayel F, Paterson MC. FISH analysis in chromophobe renal-cell carcinoma. Diagn Cytopathol. 2000 Jan; 22(1):3-6.
    View in: PubMed
  18. Iqbal MA, Ulmer C, Sakati N. Use of FISH technique in the diagnosis of chromosomal syndromes. East Mediterr Health J. 1999 Nov; 5(6):1218-24.
    View in: PubMed
  19. Iqbal MA, Akhtar M, Al Dayel F, Ulmer C, Paterson MC. Use of FISH analysis for diagnosis of renal cell carcinoma subtypes. Ann Saudi Med. 1999 Nov-Dec; 19(6):495-500.
    View in: PubMed
  20. Akhtar M, Iqbal MA, Mourad W, Ali MA. Fine-needle aspiration biopsy diagnosis of small round cell tumors of childhood: A comprehensive approach. Diagn Cytopathol. 1999 Aug; 21(2):81-91.
    View in: PubMed
  21. Iqbal MA. Chromosome telomeres: The aging clock. Ann Saudi Med. 1998 Nov-Dec; 18(6):495-6.
    View in: PubMed
  22. Iqbal MA, Manko GF, Trabin J, Virelles C, Jackson L. Cytogenetic evaluation of 1000 cases of chorionic villus sampling. Ann Saudi Med. 1998 Nov-Dec; 18(6):506-10.
    View in: PubMed
  23. Akhtar M, Iqbal MA. Genetics of small round cell tumors of children. Ann Saudi Med. 1998 Jul-Aug; 18(4):311-7.
    View in: PubMed
  24. Iqbal MA, Ahmed MZ, Wu D, Sakati N. A case of presumptive monosomy 21 re-diagnosed as unbalanced t(5p;21q) by FISH and review of literature. Am J Med Genet. 1997 May 16; 70(2):174-8.
    View in: PubMed
  25. Iqbal MA, Akhtar M, Ali MA. Cytogenetic findings in renal cell carcinoma. Hum Pathol. 1996 Sep; 27(9):949-54.
    View in: PubMed
  26. Sherwood JB, Bard R, Bhargava M, Burns ER, Iqbal MA. A human adult Wilms' tumor. Histologic, ultrastructural, and cytogenetic analysis. Cancer Genet Cytogenet. 1989 Oct 1; 42(1):35-42.
    View in: PubMed
  27. Hahm SY, Chitayat D, Iqbal MA, Cho S, Nitowsky HM. Partial duplication 16q: report of two affected siblings resulting from a maternal translocation and literature review. Clin Genet. 1987 May; 31(5):343-8.
    View in: PubMed

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