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Joshua Allen

TitleResearch Assistant Professor
InstitutionSchool of Medicine and Dentistry
DepartmentEnvironmental Medicine
AddressUniversity of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box EHSC
Rochester NY 14642
 
 Awards And Honors
2007     Ashland University Outstanding Undergraduate of the Year, 2007
2011     Society of Toxicology Graduate Student Travel Award, 2011
2013     Robert Infurna Award for best research paper as first author in peer-reviewed journal, 2013
 
 Overview
Dr. Allen is a Research Assistant Professor in the Department of Environmental Medicine. As a BIRCWH Scholar, his research will focus on how early life and in utero exposures to ambient air pollutants, including ultrafine particles, adversely affect the central nervous system. He aims to clarify the role of such exposures in the etiology of neurodevelopmental disorders, such as autism. He first became interested neurotoxicology as an undergraduate at Ashland University and continued to pursue those interests during his graduate work in toxicology at the University of Rochester School of Medicine and Dentistry. His dissertation unveiled persistent, sex-dependent neurotoxicity as a result of developmental exposure to human-relevant levels of concentrated ambient ultrafine particles in rodents. Through interactions with environmental epidemiologists while completing his graduate training, Dr. Allen developed an interest in translating his animal model research to human studies, utilizing an epidemiological approach to assess air pollutant-induced neurotoxicity, particularly for neurodevelopmental disorders. He aims to continue to increase the understanding of the role of air pollution in neurotoxicity using both basic neurotoxicological and epidemiological approaches.

 
 Selected Publications
List All   |   Timeline
  1. Weston HI, Sobolewski ME, Allen JL, Weston D, Conrad K, Pelkowski S, Watson GE, Zareba G, Cory-Slechta DA. Sex-dependent and non-monotonic enhancement and unmasking of methylmercury neurotoxicity by prenatal stress. Neurotoxicology. 2014 Mar; 41:123-40.
    View in: PubMed
  2. Allen JL, Liu X, Weston D, Conrad K, Oberdörster G, Cory-Slechta DA. Consequences of developmental exposure to concentrated ambient ultrafine particle air pollution combined with the adult paraquat and maneb model of the Parkinson's disease phenotype in male mice. Neurotoxicology. 2014 Mar; 41:80-8.
    View in: PubMed
  3. Cory-Slechta DA, Weston D, Liu S, Allen JL. Brain hemispheric differences in the neurochemical effects of lead, prenatal stress, and the combination and their amelioration by behavioral experience. Toxicol Sci. 2013 Apr; 132(2):419-30.
    View in: PubMed
  4. Allen JL, Conrad K, Oberdörster G, Johnston CJ, Sleezer B, Cory-Slechta DA. Developmental exposure to concentrated ambient particles and preference for immediate reward in mice. Environ Health Perspect. 2013 Jan; 121(1):32-8.
    View in: PubMed
  5. Cory-Slechta DA, Merchant-Borna K, Allen JL, Liu S, Weston D, Conrad K. Variations in the nature of behavioral experience can differentially alter the consequences of developmental exposures to lead, prenatal stress, and the combination. Toxicol Sci. 2012 Jan; 131(1):194-205.
    View in: PubMed
  6. Cory-Slechta DA, Stern S, Weston D, Allen JL, Liu S. Enhanced learning deficits in female rats following lifetime pb exposure combined with prenatal stress. Toxicol Sci. 2010 Oct; 117(2):427-38.
    View in: PubMed
  7. Dawson DA, Allen JL, Schultz TW, Pöch G. Time-dependence in mixture toxicity with soft-electrophiles: 2. Effects of relative reactivity level on time-dependent toxicity and combined effects for selected Michael acceptors. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2008 Jan; 43(1):43-52.
    View in: PubMed

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